| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Divya Sitaraman, Holly LaFerriere, Serge Birman, Troy Zar. Serotonin is critical for rewarded olfactory short-term memory in Drosophila. Journal of neurogenetics. vol 26. issue 2. 2012-12-07. PMID:22436011. |
examination of the function of serotonin begins to challenge the notion of one amine type per memory because altering serotonin function also reduces aversive olfactory memory and place memory levels. |
2012-12-07 |
2023-08-12 |
human |
| Divya Sitaraman, Holly LaFerriere, Serge Birman, Troy Zar. Serotonin is critical for rewarded olfactory short-term memory in Drosophila. Journal of neurogenetics. vol 26. issue 2. 2012-12-07. PMID:22436011. |
could the function of serotonin be restricted to the aversive domain, suggesting a more specific dopamine/serotonin system interaction? |
2012-12-07 |
2023-08-12 |
human |
| Oliver J Robinson, Cassie Overstreet, Phillip S Allen, Daniel S Pine, Christian Grillo. Acute tryptophan depletion increases translational indices of anxiety but not fear: serotonergic modulation of the bed nucleus of the stria terminalis? Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 8. 2012-11-13. PMID:22491355. |
recent data suggest that serotonin can inhibit aversive responding in humans, but this remains underspecified. |
2012-11-13 |
2023-08-12 |
human |
| Oliver J Robinson, Cassie Overstreet, Phillip S Allen, Daniel S Pine, Christian Grillo. Acute tryptophan depletion increases translational indices of anxiety but not fear: serotonergic modulation of the bed nucleus of the stria terminalis? Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 8. 2012-11-13. PMID:22491355. |
in particular, data in rodents suggest that global serotonin depletion may specifically increase long-duration bed nucleus of the stria terminalis (bnst)-mediated aversive responses (ie, anxiety), but not short-duration bnst-independent responses (ie, fear). |
2012-11-13 |
2023-08-12 |
human |
| S O Ogren, C H Kohler, S B Ross, B Srebr. 5-Hydroxytryptamine depletion and avoidance acquisition in the rat. Antagonism of the long-term effects of p-chloroamphetamine with a selective inhibitor of 5-hydroxytryptamine uptake. Neuroscience letters. vol 3. issue 5-6. 2012-10-02. PMID:19604909. |
5-hydroxytryptamine depletion and avoidance acquisition in the rat. |
2012-10-02 |
2023-08-12 |
rat |
| S O Ogren, C H Kohler, S B Ross, B Srebr. 5-Hydroxytryptamine depletion and avoidance acquisition in the rat. Antagonism of the long-term effects of p-chloroamphetamine with a selective inhibitor of 5-hydroxytryptamine uptake. Neuroscience letters. vol 3. issue 5-6. 2012-10-02. PMID:19604909. |
these results suggest that the impaired learning of the two-way avoidance response may be related to the long-term effects of pca on the 5-ht neurons in the rat brain. |
2012-10-02 |
2023-08-12 |
rat |
| S O Ogren, C H Kohler, S B Ross, B Srebr. 5-Hydroxytryptamine depletion and avoidance acquisition in the rat. Antagonism of the long-term effects of p-chloroamphetamine with a selective inhibitor of 5-hydroxytryptamine uptake. Neuroscience letters. vol 3. issue 5-6. 2012-10-02. PMID:19604909. |
it is concluded that 5-ht neurons may play a role in acquisition of behaviors motivated by aversive events. |
2012-10-02 |
2023-08-12 |
rat |
| J Deaki. The role of serotonin in depression and anxiety. European psychiatry : the journal of the Association of European Psychiatrists. vol 13 Suppl 2. 2012-10-02. PMID:19698674. |
the different coping responses to three types of aversive events - future threats, acute events and chronic stress - may be modulated by 5ht projections. |
2012-10-02 |
2023-08-12 |
Not clear |
| J Deaki. The role of serotonin in depression and anxiety. European psychiatry : the journal of the Association of European Psychiatrists. vol 13 Suppl 2. 2012-10-02. PMID:19698674. |
this theory proposes that dorsal raphe nucleus projections to 5ht(2) and 5ht(1d) receptors mediate anticipatory anxiety and normally motivate avoidance of threats. |
2012-10-02 |
2023-08-12 |
Not clear |
| J Deaki. The role of serotonin in depression and anxiety. European psychiatry : the journal of the Association of European Psychiatrists. vol 13 Suppl 2. 2012-10-02. PMID:19698674. |
the brain aversion system may be held in check by dorsal raphe nucleus 5ht projections to mediate behavioural inhibition during anticipatory anxiety. |
2012-10-02 |
2023-08-12 |
Not clear |
| H Furuya, H Aikawa, T Yoshida, I Okazak. Effects of ethyl alcohol administration to rat dams during the gestation period on learning behavior and on levels of monoamines and metabolites in rat pup brain after birth. Environmental health and preventive medicine. vol 1. issue 2. 2012-10-02. PMID:21432428. |
learning ability (sidman avoidance behavior), the amounts of monoamines (noradrenalin, dopamine, serotonin) and metabolites (3,4-dihydroxyphenyl acetic acid [dopac], homovanillic acid [hva] and 5-hydroxyindole acetic acid [5-hiaa])in whole brain were examined for neurobehavioral and neurochemical effects.there was no effect on sidman avoidance behavior in 56-day-old offspring, but alterations of the amounts of monoamines and their metabolites were observed even in 66-day-old offspring as a result of the dams' exposure to ethanol during pregnancy. |
2012-10-02 |
2023-08-12 |
rat |
| E A Audi, J C de Aguiar, F G Graef. Mediation by serotonin of the antiaversive effect of zimelidine and propranolol injected into the dorsal midbrain central grey. Journal of psychopharmacology (Oxford, England). vol 2. issue 1. 2012-10-02. PMID:22159666. |
previously reported results indicate that serotonin (5-ht) inhibits the neural sub strate of aversion in the dorsal midbrain central grey (dcg) of the rat. |
2012-10-02 |
2023-08-12 |
rat |
| E A Audi, J C de Aguiar, F G Graef. Mediation by serotonin of the antiaversive effect of zimelidine and propranolol injected into the dorsal midbrain central grey. Journal of psychopharmacology (Oxford, England). vol 2. issue 1. 2012-10-02. PMID:22159666. |
in addition, the present results show that microinjection of the 5-ht uptake inhibitor zimelidine (100 nmol) into the dcg of rats with chronically implanted chemitrodes raised the threshold of aversive electrical stimulation. |
2012-10-02 |
2023-08-12 |
rat |
| A Rex, C A Marsden, H Fin. 5-HT 1A receptors and changes in extracellular 5-HT in the guinea-pig prefrontal cortex: involvement in aversive behaviour. Journal of psychopharmacology (Oxford, England). vol 7. issue 4. 2012-10-02. PMID:22290997. |
5-ht 1a receptors and changes in extracellular 5-ht in the guinea-pig prefrontal cortex: involvement in aversive behaviour. |
2012-10-02 |
2023-08-12 |
rat |
| A Rex, C A Marsden, H Fin. 5-HT 1A receptors and changes in extracellular 5-HT in the guinea-pig prefrontal cortex: involvement in aversive behaviour. Journal of psychopharmacology (Oxford, England). vol 7. issue 4. 2012-10-02. PMID:22290997. |
the results show that an increase in cortical extracellular 5-ht occurs in the saline- treated guinea-pig exposed to aversive conditions. |
2012-10-02 |
2023-08-12 |
rat |
| A Rex, H Fink, M Skingle, C A Marsde. Involvement of 5 -HT1D receptors in cortical extracellular 5-HT release in guinea-pigs on exposure to the elevated plus maze. Journal of psychopharmacology (Oxford, England). vol 10. issue 3. 2012-10-02. PMID:22302948. |
under aversive conditions, exposure to the elevated plus maze, the release of extracellular 5-ht increased (155% of basal release), an effect abolished by 5-ct. pre-treatment with the selective 5.ht(1d) antagonist gr 127935 antagonized the effect of 5-ct on the aversion-induced increase in extracellular 5-ht on exposure to the elevated plus maze, but did not change the effects of 5-ct on basal 5-ht release. |
2012-10-02 |
2023-08-12 |
rat |
| A Rex, H Fink, M Skingle, C A Marsde. Involvement of 5 -HT1D receptors in cortical extracellular 5-HT release in guinea-pigs on exposure to the elevated plus maze. Journal of psychopharmacology (Oxford, England). vol 10. issue 3. 2012-10-02. PMID:22302948. |
furthermore, the results indicate that the 5-ht( 1d) receptor in the frontal cortex is functionally active under aversive conditions. |
2012-10-02 |
2023-08-12 |
rat |
| Davide Amato, Sridhar Natesan, Leonid Yavich, Shitij Kapur, Christian P Mülle. Dynamic regulation of dopamine and serotonin responses to salient stimuli during chronic haloperidol treatment. The international journal of neuropsychopharmacology. vol 14. issue 10. 2012-07-30. PMID:21281560. |
dopamine and serotonin basal levels and responses to novelty, appetitive food, and to an aversive tail pinch were measured in the prefrontal cortex, nucleus accumbens and caudate putamen using in-vivo microdialysis, and the behaviour was recorded. |
2012-07-30 |
2023-08-12 |
human |
| Ming Li, Tao Sun, Alexa Mea. Clozapine, but not olanzapine, disrupts conditioned avoidance response in rats by antagonizing 5-HT2A/2C receptors. Journal of neural transmission (Vienna, Austria : 1996). vol 119. issue 4. 2012-07-30. PMID:21986871. |
the present study was designed to assess the role of 5-ht(2a/2c) receptors in the acute and repeated effect of clozapine and olanzapine in a rat conditioned avoidance response model, a validated model of antipsychotic activity. |
2012-07-30 |
2023-08-12 |
rat |
| Ming Li, Tao Sun, Alexa Mea. Clozapine, but not olanzapine, disrupts conditioned avoidance response in rats by antagonizing 5-HT2A/2C receptors. Journal of neural transmission (Vienna, Austria : 1996). vol 119. issue 4. 2012-07-30. PMID:21986871. |
those who acquired avoidance response were administered with clozapine (10.0 mg/kg, sc) or olanzapine (1.0 mg/kg, sc) together with either saline or 1-2,5-dimethoxy-4-iodo-amphetamine (doi, a selective 5-ht(2a/2c) agonist, 1.0 or 2.5 mg/kg, sc), and their conditioned avoidance responses were tested for four consecutive days. |
2012-07-30 |
2023-08-12 |
rat |