| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Matthew W Hale, Christopher E Stamper, Daniel R Staub, Christopher A Lowr. Urocortin 2 increases c-Fos expression in serotonergic neurons projecting to the ventricular/periventricular system. Experimental neurology. vol 224. issue 1. 2010-06-28. PMID:20382145. |
serotonin plays an important role in the regulation of anxiety states and physiological responses to aversive stimuli. |
2010-06-28 |
2023-08-12 |
Not clear |
| G S Kranz, S Kasper, R Lanzenberge. Reward and the serotonergic system. Neuroscience. vol 166. issue 4. 2010-06-17. PMID:20109531. |
pharmacological studies using agonists and antagonists of serotonergic receptor subtypes and approaches investigating an increase or decrease of the extracellular level of serotonin offer strong evidence for a serotonergic mediation, ranging from aversion to pleasure. |
2010-06-17 |
2023-08-12 |
human |
| Ciara McCabe, Zevic Mishor, Philip J Cowen, Catherine J Harme. Diminished neural processing of aversive and rewarding stimuli during selective serotonin reuptake inhibitor treatment. Biological psychiatry. vol 67. issue 5. 2010-05-20. PMID:20034615. |
diminished neural processing of aversive and rewarding stimuli during selective serotonin reuptake inhibitor treatment. |
2010-05-20 |
2023-08-12 |
Not clear |
| Jermaine D Jones, F Scott Hall, George R Uhl, Anthony L Rile. Dopamine, norepinephrine and serotonin transporter gene deletions differentially alter cocaine-induced taste aversion. Pharmacology, biochemistry, and behavior. vol 94. issue 4. 2010-04-29. PMID:19969013. |
dopamine, norepinephrine and serotonin transporter gene deletions differentially alter cocaine-induced taste aversion. |
2010-04-29 |
2023-08-12 |
mouse |
| Jermaine D Jones, F Scott Hall, George R Uhl, Anthony L Rile. Dopamine, norepinephrine and serotonin transporter gene deletions differentially alter cocaine-induced taste aversion. Pharmacology, biochemistry, and behavior. vol 94. issue 4. 2010-04-29. PMID:19969013. |
monoamine transporter knockout mice have been useful in the study of many different aspects of cocaine effects relevant to human drug use and addiction, yet an assessment of the effects of deletion of the genes for the dopamine, norepinephrine and serotonin transporters (dat, net, and sert, respectively) on cocaine's aversive properties has yet to be performed (uhl et al., 2002). |
2010-04-29 |
2023-08-12 |
mouse |
| U Dannlowski, C Konrad, V Arolt, T Suslo. [Neurogenetics of emotional processes. Neuroimaging findings as endophenotypes for depression]. Der Nervenarzt. vol 81. issue 1. 2010-04-08. PMID:20013254. |
a recent study, reporting an association of the risk allele in a serotonin transporter polymorphism (5-httlpr) with increased amygdala responsiveness to aversive stimuli, stimulated the new research field of imaging genetics, which is characterized by the choice of neurobiological activity patterns as endophenotypes. |
2010-04-08 |
2023-08-12 |
Not clear |
| Avishek Adhikari, Mihir A Topiwala, Joshua A Gordo. Synchronized activity between the ventral hippocampus and the medial prefrontal cortex during anxiety. Neuron. vol 65. issue 2. 2010-03-09. PMID:20152131. |
increases in mpfc theta power predicted avoidance of the aversive compartments of each arena and were larger in serotonin 1a receptor knockout mice, a genetic model of increased anxiety-like behavior. |
2010-03-09 |
2023-08-12 |
mouse |
| J M Wheeler, C Reed, S Burkhart-Kasch, N Li, C L Cunningham, A Janowsky, F H Franken, K M Wiren, J G Hashimoto, A C Scibelli, T J Phillip. Genetically correlated effects of selective breeding for high and low methamphetamine consumption. Genes, brain, and behavior. vol 8. issue 8. 2010-02-10. PMID:19689456. |
genes differentially expressed in the drug-naï ve state, including slc6a4 (serotonin transporter), htr3a (serotonin receptor 3a), rela [nuclear factor kappab (nfkappab)] and fos (cfos), represent candidates whose expression levels may predict methamphetamine consumption and susceptibility to methamphetamine reward and aversion. |
2010-02-10 |
2023-08-12 |
mouse |
| Elin Elvander-Tottie, Therese M Eriksson, Johan Sandin, Sven Ove Ogre. 5-HT(1A) and NMDA receptors interact in the rat medial septum and modulate hippocampal-dependent spatial learning. Hippocampus. vol 19. issue 12. 2010-01-28. PMID:19309036. |
intraseptal infusion of the 5-ht(1a) receptor agonist (r)-8-oh-dpat (1 or 4 microg/rat) did not affect spatial learning in the water maze task but impaired emotional memory in the passive avoidance task at the higher dose tested (4 microg/rat). |
2010-01-28 |
2023-08-12 |
rat |
| Saori C Tanaka, Kazuhiro Shishida, Nicolas Schweighofer, Yasumasa Okamoto, Shigeto Yamawaki, Kenji Doy. Serotonin affects association of aversive outcomes to past actions. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 50. 2010-01-26. PMID:20016081. |
serotonin affects association of aversive outcomes to past actions. |
2010-01-26 |
2023-08-12 |
human |
| S O Ogren, S B Ross, A C Holm, L Bauman. 5-Hydroxytryptamine and avoidance performance in the rat. Antagonism of the acute effect of p-chloroamphetamine by zimelidine, an inhibitor of 5-hydroxytryptamine uptake. Neuroscience letters. vol 7. issue 4. 2009-12-16. PMID:19605135. |
5-hydroxytryptamine and avoidance performance in the rat. |
2009-12-16 |
2023-08-12 |
rat |
| Mattie Tops, Sascha Russo, Maarten A S Boksem, Don M Tucke. Serotonin: modulator of a drive to withdraw. Brain and cognition. vol 71. issue 3. 2009-12-09. PMID:19423206. |
one function suggested for serotonin systems is the avoidance of threat. |
2009-12-09 |
2023-08-12 |
human |
| Hirokazu Matsuzaki, Takeshi Izumi, Machiko Matsumoto, Hiroko Togashi, Taku Yamaguchi, Takayuki Yoshida, Masahiko Watanabe, Mitsuhiro Yoshiok. Early postnatal stress affects 5-HT1A receptor function in the medial prefrontal cortex in adult rats. European journal of pharmacology. vol 615. issue 1-3. 2009-11-10. PMID:19470384. |
therefore, aversive stress in the third week of the postnatal period attenuates 5-ht(1a) receptor function in the medial prefrontal cortex in adulthood and produces feedback inhibition of the raphe nuclei via postsynaptic 5-ht(1a) receptors. |
2009-11-10 |
2023-08-12 |
rat |
| Molly J Crockett, Luke Clark, Trevor W Robbin. Reconciling the role of serotonin in behavioral inhibition and aversion: acute tryptophan depletion abolishes punishment-induced inhibition in humans. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 38. 2009-10-09. PMID:19776285. |
reconciling the role of serotonin in behavioral inhibition and aversion: acute tryptophan depletion abolishes punishment-induced inhibition in humans. |
2009-10-09 |
2023-08-12 |
human |
| Molly J Crockett, Luke Clark, Trevor W Robbin. Reconciling the role of serotonin in behavioral inhibition and aversion: acute tryptophan depletion abolishes punishment-induced inhibition in humans. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 38. 2009-10-09. PMID:19776285. |
one influential hypothesis has implicated serotonin in aversive processing; another has proposed a more general role for serotonin in behavioral inhibition. |
2009-10-09 |
2023-08-12 |
human |
| Molly J Crockett, Luke Clark, Trevor W Robbin. Reconciling the role of serotonin in behavioral inhibition and aversion: acute tryptophan depletion abolishes punishment-induced inhibition in humans. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 38. 2009-10-09. PMID:19776285. |
here, we show that serotonin is critical for punishment-induced inhibition but not overall motor response inhibition or reporting aversive outcomes. |
2009-10-09 |
2023-08-12 |
human |
| Molly J Crockett, Luke Clark, Trevor W Robbin. Reconciling the role of serotonin in behavioral inhibition and aversion: acute tryptophan depletion abolishes punishment-induced inhibition in humans. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 38. 2009-10-09. PMID:19776285. |
we used acute tryptophan depletion to temporarily lower brain serotonin in healthy human volunteers as they completed a novel task designed to obtain separate measures of motor response inhibition, punishment-induced inhibition, and sensitivity to aversive outcomes. |
2009-10-09 |
2023-08-12 |
human |
| Molly J Crockett, Luke Clark, Trevor W Robbin. Reconciling the role of serotonin in behavioral inhibition and aversion: acute tryptophan depletion abolishes punishment-induced inhibition in humans. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 38. 2009-10-09. PMID:19776285. |
these findings extend and clarify previous research on the role of serotonin in aversive processing and behavioral inhibition and fit with current theorizing on the involvement of serotonin in predicting aversive outcomes. |
2009-10-09 |
2023-08-12 |
human |
| Jermaine D Jones, F Scott Hall, George R Uhl, Kenner Rice, Anthony L Rile. Differential involvement of the norepinephrine, serotonin and dopamine reuptake transporter proteins in cocaine-induced taste aversion. Pharmacology, biochemistry, and behavior. vol 93. issue 1. 2009-08-19. PMID:19376154. |
differential involvement of the norepinephrine, serotonin and dopamine reuptake transporter proteins in cocaine-induced taste aversion. |
2009-08-19 |
2023-08-12 |
Not clear |
| Jermaine D Jones, F Scott Hall, George R Uhl, Kenner Rice, Anthony L Rile. Differential involvement of the norepinephrine, serotonin and dopamine reuptake transporter proteins in cocaine-induced taste aversion. Pharmacology, biochemistry, and behavior. vol 93. issue 1. 2009-08-19. PMID:19376154. |
combined, the results of these investigations indicate little or no involvement of dopaminergic systems in cocaine's aversive effects while ne appears to contribute most substantially, with a possible modulatory involvement by serotonin. |
2009-08-19 |
2023-08-12 |
Not clear |