| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Yoon, S U Woo, J H Kang, K Kim, H-J Shin, H-S Gwak, S Park, Y-J Chwa. NF-κB and STAT3 cooperatively induce IL6 in starved cancer cells. Oncogene. vol 31. issue 29. 2012-09-25. PMID:22105366. |
the conditioned media from starved cancer cells contained various secretory factors, such as il6, il9, vwf (von willebrand factor), frem1 (fras1 related extracellular matrix 1), saa1 (serum amyloid a1), sdk1 (sidekick homolog 1) and adam12 (adam metallopeptidase domain 12), induced by nf-κb and stat3 and promoted clonogenic capacities of cancer cells, and proliferation and migration of human umbilical vein endothelial cells. |
2012-09-25 |
2023-08-12 |
human |
| Sang-Soo Lee, Ashish R Sharma, Byung-Soo Choi, Jun-Sub Jung, Jun-Dong Chang, Seonghun Park, Eduardo A Salvati, Edward P Purdue, Dong-Keun Song, Ju-Suk Na. The effect of TNFα secreted from macrophages activated by titanium particles on osteogenic activity regulated by WNT/BMP signaling in osteoprogenitor cells. Biomaterials. vol 33. issue 17. 2012-08-13. PMID:22436801. |
it has been demonstrated that conditioned medium of macrophages challenged with titanium particles (ti cm) suppresses early and late differentiation markers of osteoprogenitors, including alkaline phosphatase (alp) activity, collagen synthesis, matrix mineralization and expression of osteocalcin and runx2. |
2012-08-13 |
2023-08-12 |
Not clear |
| Sarah A Piercy-Kotb, Aisha Mousa, Hadil F Al-Jallad, Vamsee D Myneni, Florencia Chicatun, Showan N Nazhat, Mari T Kaartine. Factor XIIIA transglutaminase expression and secretion by osteoblasts is regulated by extracellular matrix collagen and the MAP kinase signaling pathway. Journal of cellular physiology. vol 227. issue 7. 2012-07-19. PMID:21959563. |
secretion of ecmfxiiia, and its enzymatic activity in conditioned medium, were also decreased in osteoblasts treated with the lysyl oxidase inhibitor β-aminopropionitrile, which resulted in a loosely packed col i matrix. |
2012-07-19 |
2023-08-12 |
Not clear |
| Mathieu Dupré, Yannick Coffinier, Rabah Boukherroub, Sonia Cantel, Jean Martinez, Christine Enjalba. Laser desorption ionization mass spectrometry of protein tryptic digests on nanostructured silicon plates. Journal of proteomics. vol 75. issue 7. 2012-07-16. PMID:22282018. |
comparison of the nanosi ms and ms/ms data with those obtained with sample conditioned in organic matrix demonstrated a great behavior for low mass responses. |
2012-07-16 |
2023-08-12 |
Not clear |
| Séverine Lecourt, Valérie Vanneaux, Audrey Cras, Delphine Freida, Djazia Heraoui, Linda Herbi, Catherine Caillaud, Christine Chomienne, Jean-Pierre Marolleau, Nadia Belmatoug, Jérôme Largher. Bone marrow microenvironment in an in vitro model of Gaucher disease: consequences of glucocerebrosidase deficiency. Stem cells and development. vol 21. issue 2. 2012-06-20. PMID:21867425. |
moreover, addition of conditioned media from cbe-treated mscs on monocyte-derived osteoclasts cultured on bone matrix leads to an increase of resorption areas. |
2012-06-20 |
2023-08-12 |
Not clear |
| Elizabeth F Martinez, Ana Paula Dias Demasi, Marcelo Henrique Napimoga, Victor Elias Arana-Chavez, Albina Altemani, Ney Soares de Araújo, Vera Cavalcanti de Araúj. In vitro influence of the extracellular matrix in myoepithelial cells stimulated by malignant conditioned medium. Oral oncology. vol 48. issue 2. 2012-06-04. PMID:21996542. |
in vitro influence of the extracellular matrix in myoepithelial cells stimulated by malignant conditioned medium. |
2012-06-04 |
2023-08-12 |
Not clear |
| Ermanno Bonucc. Bone mineralization. Frontiers in bioscience (Landmark edition). vol 17. 2012-05-24. PMID:22201735. |
as in other hard tissues, bone mineralization occurs in, and is conditioned by, the components of the organic matrix. |
2012-05-24 |
2023-08-12 |
Not clear |
| Alan J Nixon, Ashlee E Watts, Lauren V Schnabe. Cell- and gene-based approaches to tendon regeneration. Journal of shoulder and elbow surgery. vol 21. issue 2. 2012-05-16. PMID:22244071. |
research in several animal species indicates that the concept of gene-primed stem cells, particularly embryonic stem cells, combined with effective culture conditions, transduction with long-term integrating vectors carrying anabolic growth factors, and development of cells conditioned by use of rna interference gene therapy to resist matrix metalloproteinase degradation, may constitute potential advances in rotator cuff repair. |
2012-05-16 |
2023-08-12 |
human |
| Gabriella Pocsfalvi, Giuseppina Votta, Anna De Vincenzo, Immacolata Fiume, Delfin Albert Amal Raj, Giancarlo Marra, Maria Patrizia Stoppelli, Ingram Iaccarin. Analysis of secretome changes uncovers an autocrine/paracrine component in the modulation of cell proliferation and motility by c-Myc. Journal of proteome research. vol 10. issue 12. 2012-03-25. PMID:22011035. |
we also find a marked down-regulation of several structural and regulatory components of the extracellular matrix (ecm), which correlates with an increased chemotactic potency of the conditioned media toward fibroblasts, a major cellular component of tumor stroma. |
2012-03-25 |
2023-08-12 |
human |
| H Y Chiu, C W Chen, H T Lin, C C Hsieh, S S Lin, C M Chen. Study of gastric fluid induced cytokine and chemokine expression in airway smooth muscle cells and airway remodeling. Cytokine. vol 56. issue 3. 2012-03-15. PMID:21996013. |
matrix metalloproteinase 2 expressions in airway smcs was enhanced by gastric fluid and conditioned medium. |
2012-03-15 |
2023-08-12 |
rat |
| Chris S Hughes, Lida Radan, Dean Betts, Lynne M Postovit, Gilles A Lajoi. Proteomic analysis of extracellular matrices used in stem cell culture. Proteomics. vol 11. issue 20. 2012-02-14. PMID:21834137. |
in this study, we performed the proteomic analysis of five previously uncharacterized matrices: cellstart, human basement membrane extract (human bme), stemxvivo, bridge human extracellular matrix (bridgeecm), and mouse embryonic fibroblast conditioned matrix (mef-cmtx). |
2012-02-14 |
2023-08-12 |
mouse |
| Stefan Tholen, Martin L Biniossek, Anna-Lena Gessler, Sebastian Müller, Juliane Weisser, Jayachandran N Kizhakkedathu, Thomas Reinheckel, Oliver Schillin. Contribution of cathepsin L to secretome composition and cleavage pattern of mouse embryonic fibroblasts. Biological chemistry. vol 392. issue 11. 2012-01-23. PMID:21972973. |
quantitative proteomic comparison of cell conditioned media indicated that cathepsin l deficiency affects, albeit in a limited manner, the abundances of extracellular matrix (ecm) components, signaling proteins, and further proteases as well as endogenous protease inhibitors. |
2012-01-23 |
2023-08-12 |
mouse |
| Svetlana Gingis-Velitski, David Loven, Liat Benayoun, Michal Munster, Rotem Bril, Tali Voloshin, Dror Alishekevitz, Francesco Bertolini, Yuval Shake. Host response to short-term, single-agent chemotherapy induces matrix metalloproteinase-9 expression and accelerates metastasis in mice. Cancer research. vol 71. issue 22. 2011-12-27. PMID:21978934. |
conditioned medium from bmdcs and plasma from chemotherapy-treated mice each promoted metastatic properties in tumor cells by inducing matrix metalloproteinase-9 (mmp9) and epithelial-to-mesenchymal transition. |
2011-12-27 |
2023-08-12 |
mouse |
| Kristen A England, Andrew P Price, Kevin V Tram, Steven D Shapiro, Bruce R Blazar, Angela Panoskaltsis-Mortar. Evidence for early fibrosis and increased airway resistance in bone marrow transplant recipient mice deficient in MMP12. American journal of physiology. Lung cellular and molecular physiology. vol 301. issue 4. 2011-12-19. PMID:21784967. |
because matrix metalloproteinase 12 (mmp12) is important for macrophage infiltration and injury in other mouse models of lung disease such as emphysema, lethally conditioned mmp12(-/-) mice were used as allogeneic recipients to determine whether mmp12 plays a similar role in potentiating lung injury in ips. |
2011-12-19 |
2023-08-12 |
mouse |
| Yunyuan Li, Ruhangiz T Kilani, Ryan Hartwell, Aziz Ghahar. MAP kinase mediates silica-induced fibrotic nodule formation and collagen accumulation in fibroblasts. Journal of cellular physiology. vol 227. issue 1. 2011-12-08. PMID:21437902. |
the findings further revealed that silica gel stimulates collagen and fibronectin expression, while down-regulates matrix metalloproteinase-1 and -3 (mmp-1 and mmp-3) released in conditioned medium. |
2011-12-08 |
2023-08-12 |
human |
| Mitsutoshi Tominaga, Suhandy Tengara, Atsuko Kamo, Hideoki Ogawa, Kenji Takamor. Matrix metalloproteinase-8 is involved in dermal nerve growth: implications for possible application to pruritus from in vitro models. The Journal of investigative dermatology. vol 131. issue 10. 2011-11-23. PMID:21697883. |
levels of matrix metalloproteinase-8 (mmp-8) mrna and protein were increased in the cultured neurons and the conditioned medium, respectively. |
2011-11-23 |
2023-08-12 |
rat |
| Evgenios A Neofytou, Edwin Chang, Bhagat Patlola, Lydia-Marie Joubert, Jayakumar Rajadas, Sanjiv S Gambhir, Zhen Cheng, Robert C Robbins, Ramin E Beygu. Adipose tissue-derived stem cells display a proangiogenic phenotype on 3D scaffolds. Journal of biomedical materials research. Part A. vol 98. issue 3. 2011-11-10. PMID:21630430. |
increased vegf levels were seen in conditioned media harvested from co-cultures of ascs and b.end-3 on either matrigel or a 3d matrix. |
2011-11-10 |
2023-08-12 |
mouse |
| Yan Huang, Avis E Simms, Anna Mazur, Sophie Wang, Noel R León, Barry Jones, Nazneen Aziz, Thomas Kell. Fibroblast activation protein-α promotes tumor growth and invasion of breast cancer cells through non-enzymatic functions. Clinical & experimental metastasis. vol 28. issue 6. 2011-09-23. PMID:21604185. |
in vitro studies revealed that cells expressing wild type fap or fap(s624a) degrade extracellular matrix (ecm) more extensively, accumulate higher levels of matrix metalloproteinase-9 (mmp-9) in conditioned medium, are more invasive in type i collagen gels, and have altered signaling compared to control transfectants that do not express fap and form slow growing tumors. |
2011-09-23 |
2023-08-12 |
mouse |
| Gwendolyn Sowa, Paulo Coelho, Nam Vo, Ron Bedison, Andrew Chiao, Cara Davies, Rebecca Studer, James Kan. Determination of annulus fibrosus cell response to tensile strain as a function of duration, magnitude, and frequency. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 29. issue 8. 2011-08-23. PMID:21671263. |
conditioned media were analyzed for matrix metalloprotease activity and production of prostaglandin e(2) . |
2011-08-23 |
2023-08-12 |
rabbit |
| Zhiyong Chen, X-C May Lu, Deborah A Shear, Jitendra R Dave, Angela R Davis, Clifford A Evangelista, Danelle Duffy, Frank C Tortell. Synergism of human amnion-derived multipotent progenitor (AMP) cells and a collagen scaffold in promoting brain wound recovery: pre-clinical studies in an experimental model of penetrating ballistic-like brain injury. Brain research. vol 1368. 2011-06-30. PMID:20951684. |
amp cells suspended in amp cell conditioned medium (accs) or in a liquefied collagen matrix were injected immediately after a pbbi along the penetrating injury tract. |
2011-06-30 |
2023-08-12 |
human |