| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Robyn R Mercer, Chiaki Miyasaka, Andrea M Mastr. Metastatic breast cancer cells suppress osteoblast adhesion and differentiation. Clinical & experimental metastasis. vol 21. issue 5. 2005-03-08. PMID:15672867. |
osteoblasts cultured with mda-mb-231 conditioned medium did not express these mature bone proteins, nor did they mineralize a matrix. |
2005-03-08 |
2023-08-12 |
Not clear |
| Tadahiro Takayama, Naoto Suzuki, Masataka Narukawa, Harvey A Goldberg, Kichibee Otsuka, Koichi It. Enamel matrix derivative is a potent inhibitor of breast cancer cell attachment to bone. Life sciences. vol 76. issue 11. 2005-03-07. PMID:15642592. |
conditioned human osteosarcoma cell (saos-2) medium was used as extracellular bone matrix (ecbm) to measure cell attachment. |
2005-03-07 |
2023-08-12 |
human |
| Aziz Ghahary, Yvonne Marcoux, Feridoun Karimi-Busheri, Yunyaun Li, Edward E Tredget, Ruhangiz T Kilani, Eugene Lam, Michael Weinfel. Differentiated keratinocyte-releasable stratifin (14-3-3 sigma) stimulates MMP-1 expression in dermal fibroblasts. The Journal of investigative dermatology. vol 124. issue 1. 2005-03-07. PMID:15654971. |
to address this hypothesis, in a longitudinal study, keratinocyte differentiation was induced by growing these cells in a medium consisting of 50% keratinocyte serum-free medium (ksfm) and 50% dulbecco's modified eagle's medium without any additives for up to 20 d. when kcm was collected every other day and added to fibroblasts, the level of matrix metalloproteinase (mmp)-1 mrna expression was markedly increased in fibroblasts receiving kcm and this increase was even greater in cells receiving conditioned media collected at later time points relative to that of controls. |
2005-03-07 |
2023-08-12 |
Not clear |
| Natalia Yu Yevdokimova, Sergey V Komisarenk. TGFbeta1 is involved in high glucose-induced accumulation of pericellular chondroitin sulphate in human endothelial cells. Journal of diabetes and its complications. vol 18. issue 5. 2005-02-18. PMID:15337504. |
according to our data, confluent cells exposed to 30 mm glucose for 48 h secrete the increased amount of total and active tgfbeta1 ( approximately 1.4-fold), and accumulate more chondroitin sulphate (cs) in their conditioned medium, pericellular matrix, and cell layer ( approximately 1.6- to 2.0-fold). |
2005-02-18 |
2023-08-12 |
human |
| Jens J Kaden, Carl-Erik Dempfle, Refika Kiliç, Aslihan Sarikoç, Siegfried Hagl, Siegfried Lang, Martina Brueckmann, Martin Borggref. Influence of receptor activator of nuclear factor kappa B on human aortic valve myofibroblasts. Experimental and molecular pathology. vol 78. issue 1. 2005-02-01. PMID:15596058. |
matrix metalloproteinase (mmp)-1 was detectable time-dependently in conditioned media from rankl-stimulated cells, but absent in media from control cells. |
2005-02-01 |
2023-08-12 |
human |
| Xiaoli Shi, Beena Gangadharan, Lawrence F Brass, Wolfram Ruf, Barbara M Muelle. Protease-activated receptors (PAR1 and PAR2) contribute to tumor cell motility and metastasis. Molecular cancer research : MCR. vol 2. issue 7. 2005-01-28. PMID:15280447. |
thrombin also stimulates chemokinesis of human melanoma cells toward fibroblast conditioned media and soluble matrix proteins. |
2005-01-28 |
2023-08-12 |
human |
| S V McLennan, X Y Wang, V Moreno, D K Yue, S M Twig. Connective tissue growth factor mediates high glucose effects on matrix degradation through tissue inhibitor of matrix metalloproteinase type 1: implications for diabetic nephropathy. Endocrinology. vol 145. issue 12. 2004-12-23. PMID:15345671. |
addition of timp-1 antibody to conditioned medium abolished the decrease in degradation caused by rhctgf and partially prevented (by 79%) the glucose-induced inhibition of matrix degradation. |
2004-12-23 |
2023-08-12 |
human |
| Shirly Lahav-Baratz, Hanna Shiloh, Mara Koifman, Zaki Kraiem, Zofnat Wiener-Megnazi, David Ishai, Martha Dirnfel. Early embryo-endometrial signaling modulates the regulation of matrix metalloproteinase-3. Fertility and sterility. vol 82 Suppl 3. 2004-11-19. PMID:15474069. |
to examine matrix metalloproteinase-3 (mmp-3) expression in human stromal cell culture after p stimulation and the effect of conditioned medium from human embryo-epithelial cells coculture on its expression and activity. |
2004-11-19 |
2023-08-12 |
human |
| Natalia Yu Yevdokimov. High glucose-induced alterations of extracellular matrix of human skin fibroblasts are not dependent on TSP-1-TGFbeta1 pathway. Journal of diabetes and its complications. vol 17. issue 6. 2004-07-22. PMID:14583181. |
we investigated the response of human skin fibroblasts to elevated glucose level (11.0 and 30.0 mm) in terms of: (1) the expression and secretion of fibronectin (fn) and plasminogen activator inhibitor-1 (pai-1); (2) the accumulation of hyaluronic acid (ha) in pericellular matrix and in the conditioned medium; (3) tgfbeta1 expression, secretion and activation; (4) tsp-1 expression and secretion. |
2004-07-22 |
2023-08-12 |
human |
| Ursula Mirastschijski, Daniel Konrad, Eva Lundberg, Staale Petter Lyngstadaas, Lars N Jorgensen, Magnus S Agre. Effects of a topical enamel matrix derivative on skin wound healing. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 12. issue 1. 2004-06-22. PMID:14974971. |
in cultured fibroblasts, vascular endothelial growth factor levels in conditioned media were increased more than fivefold (p < 0.001) with enamel matrix derivative treatment (0.1mg/ml) over control, measured by specific enzyme-linked immunosorbent assay. |
2004-06-22 |
2023-08-12 |
Not clear |
| Liviu P Lefter, Makoto Sunamura, Toru Furukawa, Kazunori Takeda, Noriko Kotobuki, Mitsuo Oshimura, Seiki Matsuno, Akira Hori. Inserting chromosome 18 into pancreatic cancer cells switches them to a dormant metastatic phenotype. Clinical cancer research : an official journal of the American Association for Cancer Research. vol 9. issue 13. 2004-06-10. PMID:14581380. |
on the other hand, significantly lower vascular endothelial growth factor and matrix metalloproteinase 2 secretion was observed by measuring levels in the conditioned media (cm); the averages were 22% and 20%, respectively. |
2004-06-10 |
2023-08-12 |
mouse |
| J E Nutt, H P Lazarowicz, J K Mellon, J Lune. Gefitinib ('Iressa', ZD1839) inhibits the growth response of bladder tumour cell lines to epidermal growth factor and induces TIMP2. British journal of cancer. vol 90. issue 8. 2004-05-26. PMID:15083203. |
zymography of the conditioned medium from rt112 cells treated with egf and gefitinib showed a decrease in matrix metalloproteinase 2 (mmp2) concentrations. |
2004-05-26 |
2023-08-12 |
human |
| S Goldman, A Weiss, V Eyali, E Shale. Differential activity of the gelatinases (matrix metalloproteinases 2 and 9) in the fetal membranes and decidua, associated with labour. Molecular human reproduction. vol 9. issue 6. 2004-05-03. PMID:12771238. |
we found that in media conditioned by decidua, following the establishment of uterine contractions, matrix metalloproteinase-2 (mmp-2) activity is increased while the protein tissue inhibitors of matrix metalloproteinase-1 (timp-1) level is decreased. |
2004-05-03 |
2023-08-12 |
human |
| P Elliott, A Hohmann, J Spano. Protease expression in the supernatant of Chinese hamster ovary cells grown in serum-free culture. Biotechnology letters. vol 25. issue 22. 2004-04-06. PMID:14719832. |
immunoblotting of the conditioned medium showed the gelatinase to be the pro- form of matrix metalloprotease-9 (pro-mmp-9), also known as gelatinase b. |
2004-04-06 |
2023-08-12 |
Not clear |
| Diana Campioni, Marina Punturieri, Antonella Bardi, Sabrina Moretti, Elisa Tammiso, Francesco Lanza, Gianluigi Castold. "In vitro" evaluation of bone marrow angiogenesis in myelodysplastic syndromes: a morphological and functional approach. Leukemia research. vol 28. issue 1. 2004-02-17. PMID:14630075. |
in order to test the significance of the endothelial growth in mds patients, two in vitro assays are presented in this study: a long-term culture method for the detection of human bone marrow endothelial colonies (cfu-en) (77 patients) and a human primary model for the evaluation of the influence of a "bone marrow conditioned medium" on the formation of new vessels in a culture matrix ("angio-kit assay") (in 24 out 77 patients). |
2004-02-17 |
2023-08-12 |
human |
| N Yu Yevdokimova, S V Komisarenk. The influence of high ambient glucose level on the production of pericellular glycosaminoglycans by cultured endothelial cells. Ukrains'kyi biokhimichnyi zhurnal (1999 ). vol 75. issue 5. 2004-02-10. PMID:14681993. |
it is demonstrated that 30 mm glucose decreased the accumulation of hs and increased the accumulation of cs and ds in the cell layer, pericellular matrix and conditioned medium in 48 h of incubation. |
2004-02-10 |
2023-08-12 |
human |
| N Yu Yevdokimova, S V Komisarenk. The influence of high ambient glucose level on the production of pericellular glycosaminoglycans by cultured endothelial cells. Ukrains'kyi biokhimichnyi zhurnal (1999 ). vol 75. issue 5. 2004-02-10. PMID:14681993. |
the modulation of the overall metabolism of sulphated gags by high glucose is in contrast to the observed redistribution of ha from the conditioned medium to the pericellular matrix of endothelial cells. |
2004-02-10 |
2023-08-12 |
human |
| Peter Jordan, John A Fitzpatrick, Craig Meskel. Beampattern control of a microphone array to minimize secondary source contamination. The Journal of the Acoustical Society of America. vol 114. issue 4 Pt 1. 2004-01-14. PMID:14587592. |
it is shown that, for the technique to work with actual data, the cross-spectral matrix must be conditioned before array shading is implemented. |
2004-01-14 |
2023-08-12 |
Not clear |
| Y Nishizawa, F Fukai, Y Natori, R Kato, S Tanuma, T Katayam. Mesangial cell apoptosis induced by a fibronectin fragment. Apoptosis : an international journal on programmed cell death. vol 3. issue 6. 2003-12-23. PMID:14646473. |
furthermore, gelatinzymography of the conditioned medium of mesangial cells showed that the 150 k fn fragment induced and/or potentiated the extracellular matrix (ecm)-degrading proteinases including matrix metalloproteinases (mmps) of mesangial cells. |
2003-12-23 |
2023-08-12 |
rat |
| A Sculean, R Junker, N Donos, P Windisch, M Brecx, N Dünke. Immunohistochemical evaluation of matrix molecules associated with wound healing following treatment with an enamel matrix protein derivative in humans. Clinical oral investigations. vol 7. issue 3. 2003-12-09. PMID:12827455. |
application of enamel matrix protein derivative (emd) onto a debrided and conditioned root surface has been shown to promote periodontal regeneration in animals and humans. |
2003-12-09 |
2023-08-12 |
human |