All Relations between conditioned response and matrix compartment

Publication Sentence Publish Date Extraction Date Species
Shreoshi Sengupta, Mainak Mondal, Kaval Reddy Prasasvi, Arani Mukherjee, Prerna Magod, Serge Urbach, Dinorah Friedmann-Morvinski, Philippe Marin, Kumaravel Somasundara. Differentiated glioma cell-derived Fibromodulin activates Integrin-dependent Notch signaling in endothelial cells to promote tumor angiogenesis and growth. eLife. vol 11. 2022-06-01. PMID:35642785. proteomic analysis showed a higher abundance of the extracellular matrix small leucine-rich proteoglycan fibromodulin (fmod) in the conditioned medium of differentiated glioma cells (dgcs), the equivalent of glioma non-cscs, compared to that of glioma stem-like cells (gscs). 2022-06-01 2023-08-13 Not clear
Angelo Savio Calabrese, Tommaso D'Antino, Pierluigi Colombi, Carlo Pogg. Long-Term Behavior of PBO FRCM and Comparison with Other Inorganic-Matrix Composites. Materials (Basel, Switzerland). vol 15. issue 9. 2022-05-20. PMID:35591615. the effect of various aggressive environments on the composite matrix cracking stress, composite tensile strength, ultimate strain, and fully cracked stage slope is investigated by comparing the results of nominally equal conditioned and unconditioned (control) specimens. 2022-05-20 2023-08-13 Not clear
George Hsiao, Wei-Chiung Chi, Chia-Hao Chang, Yin-Ru Chiang, Yan-Jie Fu, Tzong-Huei Le. Bioactive pulvinones from a marine algicolous fungus Aspergillus terreus NTU243. Phytochemistry. 2022-05-14. PMID:35568258. additionally, zymography showed that the conditioned medium of thp-1 cells post-lps challenged significantly enhanced matrix metalloproteinase (mmp)-9-mediated gelatinolysis, and pretreatment with aspulvinones u and v significantly attenuated mmp-9-mediated gelatinolysis by 45.7% and 63.9%, separately. 2022-05-14 2023-08-13 Not clear
Patrisia Mattioli, Olufela Koleoso, Ashley Otto, Twinkle Saini, Christine Shind, Emily Baus, Amy Bhatt, Marina D'Angel. Chronic Obstructive Pulmonary Diseased Human Lung Fibroblasts Secrete Increased Matrix Metalloproteases -12 and -8. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35557474. there were detectable levels of mmp-12 (ng/culture) and mmp-8 (pg/culture) in both the secreted (conditioned media) and incorporated (extracellular matrix) fractions. 2022-05-13 2023-08-13 human
Shen Li, Matthias Zenkel, Friedrich E Kruse, Andreas Gießl, Ursula Schlötzer-Schrehard. Identification, Isolation, and Characterization of Melanocyte Precursor Cells in the Human Limbal Stroma. International journal of molecular sciences. vol 23. issue 7. 2022-04-12. PMID:35409129. in both melanocyte populations, limbus-specific matrix (laminin 511-e8) and soluble factors (lepc-derived conditioned medium) stimulated melanocyte adhesion, dendrite formation, melanogenesis, and expression of genes involved in uv protection and immune regulation. 2022-04-12 2023-08-13 human
b' Lidija Filipovi\\xc4\\x87, Milica Spasojevi\\xc4\\x87, Radivoje Prodanovi\\xc4\\x87, Aleksandra Kora\\xc4\\x87, Suzana Matija\\xc5\\xa1evic, Goran Braju\\xc5\\xa1kovic, Ario de Marco, Milica Popovi\\xc4\\x8. Affinity-based isolation of extracellular vesicles by means of single-domain antibodies bound to macroporous methacrylate-based copolymer. New biotechnology. 2022-03-18. PMID:35301156.' an easy-to-operate chromatography system was set-up for the purification of intact evs based on a single domain (vhh) antibodies-copolymer matrix suitable for biological samples as different as conditioned cell culture medium and human plasma. 2022-03-18 2023-08-13 human
Maria I Falguera Uceda, Silvia Sánchez-Casanova, Clara Escudero-Duch, Nuria Vilabo. A Narrative Review of Cell-Based Approaches for Cranial Bone Regeneration. Pharmaceutics. vol 14. issue 1. 2022-01-21. PMID:35057028. further, we discuss strategies to deliver extracellular matrix, conditioned media and extracellular vesicles derived from cell cultures. 2022-01-21 2023-08-13 human
Shuo Zhang, Peng Wang, Binwu Hu, Weijian Liu, Xiao Lv, Songfeng Chen, Zengwu Sha. HSP90 Inhibitor 17-AAG Attenuates Nucleus Pulposus Inflammation and Catabolism Induced by M1-Polarized Macrophages. Frontiers in cell and developmental biology. vol 9. 2022-01-21. PMID:35059401. the conditioned medium (cm) of inflamed np cells (npcs) enhanced m1 polarization of macrophages, while the cm of m1 macrophages but not m2 macrophages promoted the expression of inflammatory factors and matrix proteases in npcs. 2022-01-21 2023-08-13 human
Whitney M Longmate, Rakshitha Pandulal Miskin, Livingston Van De Water, C Michael DiPersi. Epidermal Integrin α3β1 Regulates Tumor-Derived Proteases BMP-1, Matrix Metalloprotease-9, and Matrix Metalloprotease-3. JID innovations. vol 1. issue 2. 2021-12-15. PMID:34909716. in this study, analysis of immortalized keratinocyte lines and their conditioned media support a role for α3β1 in regulating the expression of several extracellular proteases of the keratinocyte secretome, namely bmp-1, matrix metalloprotease (mmp)-9, and mmp-3. 2021-12-15 2023-08-13 mouse
Zhikui Liu, Huanye Mo, Runkun Liu, Yongshen Niu, Tianxiang Chen, Qiuran Xu, Kangsheng Tu, Nan Yan. Matrix stiffness modulates hepatic stellate cell activation into tumor-promoting myofibroblasts via E2F3-dependent signaling and regulates malignant progression. Cell death & disease. vol 12. issue 12. 2021-12-07. PMID:34873170. on a stiff matrix, hcc cells cultured with conditioned media (cm) from hscs increased hcc cells growth and metastasis by binding fgfr1 to activate pi3k/akt and mek/erk signaling pathways. 2021-12-07 2023-08-13 mouse
Emerito Carlos Rodríguez-Merchá. Anterior Cruciate Ligament Reconstruction: Is Biological Augmentation Beneficial? International journal of molecular sciences. vol 22. issue 22. 2021-11-30. PMID:34830448. they include: (1) growth factors (bone morphogenetic protein, epidermal growth factor, granulocyte colony-stimulating factor, basic fibroblast growth factor, transforming growth factor-β, hepatocyte growth factor, vascular endothelial growth factor, and platelet concentrates such as platelet-rich plasma, fibrin clot, and autologous conditioned serum), (2) mesenchymal stem cells, (3) autologous tissue, (4) various pharmaceuticals (matrix metalloproteinase-inhibitor alpha-2-macroglobulin bisphosphonates), (5) biophysical/environmental methods (hyperbaric oxygen, low-intensity pulsed ultrasound, extracorporeal shockwave therapy), (6) biomaterials (fixation methods, biological coatings, biosynthetic bone substitutes, osteoconductive materials), and (7) gene therapy. 2021-11-30 2023-08-13 Not clear
Yangmengfan Chen, Maximilian M Menger, Benedikt J Braun, Sara Schweizer, Caren Linnemann, Karsten Falldorf, Michael Ronniger, Hongbo Wang, Tina Histing, Andreas K Nussler, Sabrina Ehner. Modulation of Macrophage Activity by Pulsed Electromagnetic Fields in the Context of Fracture Healing. Bioengineering (Basel, Switzerland). vol 8. issue 11. 2021-11-28. PMID:34821733. furthermore, the conditioned medium from macrophages exposed to field b, but not to field a, stimulated the expression of extracellular matrix genes in scp-1 cells, i.e., 2021-11-28 2023-08-13 Not clear
Saumya Mishra, Charul Rajput, Mahendra Pratap Sing. Cypermethrin Induces the Activation of Rat Primary Microglia and Expression of Inflammatory Proteins. Journal of molecular neuroscience : MN. vol 71. issue 6. 2021-11-23. PMID:33230707. cypermethrin augmented the protein kinase c-δ (pkc-δ), inducible nitric oxide synthase (inos), phosphorylated mitogen-activated protein kinase (mapk) p38 and p42/44, matrix metalloproteinase (mmp)-3, and mmp-9 levels in the cell lysate and tumour necrosis factor-α (tnf-α) and interleukin-1β (il-1β) levels in the microglia conditioned media. 2021-11-23 2023-08-13 rat
Liudi Yao, Yilu Zhou, Juanjuan Li, Leanne Wickens, Franco Conforti, Anna Rattu, Fathima Maneesha Ibrahim, Aiman Alzetani, Ben G Marshall, Sophie V Fletcher, David Hancock, Tim Wallis, Julian Downward, Rob M Ewing, Luca Richeldi, Paul Skipp, Donna E Davies, Mark G Jones, Yihua Wan. Bidirectional epithelial-mesenchymal crosstalk provides self-sustaining profibrotic signals in pulmonary fibrosis. The Journal of biological chemistry. vol 297. issue 3. 2021-11-17. PMID:34418430. rna-seq of lung fibroblasts exposed to conditioned media from atii cells undergoing ras-induced epithelial-mesenchymal transition identified many differentially expressed genes including those involved in cell migration and extracellular matrix regulation. 2021-11-17 2023-08-13 human
Pei-Ni Chen, Chiao-Wen Lin, Shun-Fa Yang, Yu-Chao Chan. Oral submucous fibrosis stimulates invasion and epithelial-mesenchymal transition in oral squamous cell carcinoma by activating MMP-2 and IGF-IR. Journal of cellular and molecular medicine. vol 25. issue 20. 2021-11-16. PMID:34528373. the results showed that the conditioned medium (cm) of fibrotic buccal mucosal fibroblasts (fbmfs) strongly induced the invasion of oral cancer cells and increased the activities of matrix metalloproteinase-2. 2021-11-16 2023-08-13 human
Go Itoh, Kurara Takagane, Yuma Fukushi, Sei Kuriyama, Michinobu Umakoshi, Akiteru Goto, Kazuyoshi Yanagihara, Masakazu Yashiro, Masamitsu Tanak. Cancer-associated fibroblasts educate normal fibroblasts to facilitate cancer cell spreading and T-cell suppression. Molecular oncology. 2021-11-06. PMID:34379869. when nfs were incubated with conditioned medium from cafs, the resulting caf-educated fibroblasts (cefs) generated reactive oxygen species, which induced nf-κb-mediated expression of inflammatory cytokines and the extracellular matrix protein asporin (aspn), while expression of a common caf marker gene, α-sma, was not increased. 2021-11-06 2023-08-13 Not clear
Hong Cao, Li Qiang, Jing Chen, Katherine M Johnson, Mark A McNiven, Gina L Razidl. Synergistic metalloproteinase-based remodeling of matrix by pancreatic tumor and stromal cells. PloS one. vol 16. issue 3. 2021-10-14. PMID:33740019. we find that tumor cells co-cultured with the conditioned medium from stromal fibroblasts exhibited a substantial increase in invadopodial-based matrix degradation and transwell invasion. 2021-10-14 2023-08-13 Not clear
Alyaa S Abdel Halim, Hanaa H Ahmed, Hadeer A Aglan, Fatma F Abdel Hamid, Mohamed R Mohame. Role of bone marrow-derived mesenchymal stem cells in alleviating pulmonary epithelium damage and extracellular matrix remodeling in a rat model of lung fibrosis induced by amiodarone. Biotechnic & histochemistry : official publication of the Biological Stain Commission. vol 96. issue 6. 2021-09-17. PMID:32909452. we investigated the potential curative effect of bone marrow-derived mscs (bm-mscs) and conditioned media (cm) from bm-mscs on ad induced pf by focusing on pulmonary epithelium injury and repair, and extracellular matrix (ecm) remodeling. 2021-09-17 2023-08-13 rat
Jiraporn Kantapan, Nampeung Anukul, Nipapan Leetrakool, Gwenaël Rolin, Jackie Vergote, Nathupakorn Dechsup. Iron-Quercetin Complex Preconditioning of Human Peripheral Blood Mononuclear Cells Accelerates Angiogenic and Fibroblast Migration: Implications for Wound Healing. International journal of molecular sciences. vol 22. issue 16. 2021-09-13. PMID:34445558. the conditioned medium obtained from ironq-treated pbmcs contained high levels of interleukin 8 (il-8), il-10, urokinase-type-plasminogen-activator (upa), matrix metalloproteinases-9 (mmp-9), and tumor necrosis factor-alpha (tnf-α), as well as augmented migration and capillary network formation of huvecs and fibroblast cells, in vitro. 2021-09-13 2023-08-13 human
Reaz Vawda, Anna Badner, James Hong, Mirriam Mikhail, Rachel Dragas, Kristiana Xhima, Alejandro Jose, Michael G Fehling. Harnessing the Secretome of Mesenchymal Stromal Cells for Traumatic Spinal Cord Injury: Multicell Comparison and Assessment of In Vivo Efficacy. Stem cells and development. vol 29. issue 22. 2021-09-03. PMID:32962528. in this study, we compare the efficacy of intravenously delivered concentrated conditioned media (cm) from human umbilical cord matrix cells (hucmcs), bone marrow mesenchymal stromal cells, as well as newborn and adult fibroblasts in a rat model of moderately severe cervical clip compression/contusion injury (c7--t1, 35 g). 2021-09-03 2023-08-13 human