| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N Ata, T Oku, M Hattori, H Fujii, M Nakajima, I Saik. Inhibition by galloylglucose (GG6-10) of tumor invasion through extracellular matrix and gelatinase-mediated degradation of type IV collagens by metastatic tumor cells. Oncology research. vol 8. issue 12. 1997-07-21. PMID:9160354. |
the gelatin zymography revealed that gg6-10 was able to inhibit not only the degradation of gelatin mediated by matrix metalloproteinases (mmp)-2 and -9 in conditioned medium of ht-1080 tumor cells but also the production of mmp from the tumor cells in a concentration-dependent manner. |
1997-07-21 |
2023-08-12 |
Not clear |
| Y Koshihara, K Hosh. Vitamin K2 enhances osteocalcin accumulation in the extracellular matrix of human osteoblasts in vitro. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 12. issue 3. 1997-06-06. PMID:9076586. |
with the addition of vitamin k2 (1.5-5.0 microm), osteocalcin accumulation in the extracellular matrix of the osteoblasts was increased, but the osteocalcin content in the conditioned medium decreased, in comparison with that treated with 10-9 m 1,25(oh)2d3 alone. |
1997-06-06 |
2023-08-12 |
human |
| J P Schmitz, D D Dean, Z Schwartz, D L Cochran, G M Grant, R J Klebe, H Nakaya, B D Boya. Chondrocyte cultures express matrix metalloproteinase mRNA and immunoreactive protein; stromelysin-1 and 72 kDa gelatinase are localized in extracellular matrix vesicles. Journal of cellular biochemistry. vol 61. issue 3. 1997-04-29. PMID:8761942. |
substrate gel electrophoresis and western analysis were used to characterize mmp activity in matrix vesicles, media vesicles, or plasma membranes as well as in conditioned media produced by the chondrocyte cultures. |
1997-04-29 |
2023-08-12 |
Not clear |
| C I Sartor, M L Dziubinski, C L Yu, R Jove, S P Ethie. Role of epidermal growth factor receptor and STAT-3 activation in autonomous proliferation of SUM-102PT human breast cancer cells. Cancer research. vol 57. issue 5. 1997-03-28. PMID:9041204. |
conditioned medium from sum-102pt cells contains an egf-like mitogen that binds to a heparin-agarose affinity matrix with high affinity. |
1997-03-28 |
2023-08-12 |
human |
| T Yasuda, S Kondo, T Homma, R C Harri. Regulation of extracellular matrix by mechanical stress in rat glomerular mesangial cells. The Journal of clinical investigation. vol 98. issue 9. 1997-01-03. PMID:8903317. |
gelatinolytic activity in conditioned media was decreased at 24 and 48 h of stretch/relaxation, in association with a significant decrease in levels of mrna for matrix metalloproteinase-2 (68-72 kd type iv collagenase) occurring within 6 h of stretch/relaxation. |
1997-01-03 |
2023-08-12 |
rat |
| N Utoguchi, H Mizuguchi, K Saeki, K Ikeda, S Nakagawa, T Mayum. Effects of rat hepatocytes on macromolecular permeability of bovine aortic endothelial cell monolayer. International journal of microcirculation, clinical and experimental. vol 16. issue 2. 1996-12-05. PMID:8737714. |
the conditioned medium of p-hep did not alter the baec monolayer permeability, nor did the extracellular matrix of p-hep alter baec permeability. |
1996-12-05 |
2023-08-12 |
rat |
| D W Cottam, R H Corbitt, D E Gomez, R C Rees, U P Thorgeirsso. Alterations in endothelial cell proteinase and inhibitor polarized secretion following treatment with interleukin-1, phorbol ester, and human melanoma cell conditioned medium. Journal of cellular biochemistry. vol 60. issue 1. 1996-11-20. PMID:8825424. |
matrix metalloproteinase-9 activity was induced by phorbol 12-myristate 13-acetate (apical), interleukin-1 alpha (basal), and by conditioned medium from dx3 human melanoma cells (basal). |
1996-11-20 |
2023-08-12 |
human |
| D W Cottam, R H Corbitt, D E Gomez, R C Rees, U P Thorgeirsso. Alterations in endothelial cell proteinase and inhibitor polarized secretion following treatment with interleukin-1, phorbol ester, and human melanoma cell conditioned medium. Journal of cellular biochemistry. vol 60. issue 1. 1996-11-20. PMID:8825424. |
the dx3 melanoma conditioned medium also stimulated basal secretion of matrix metalloproteinase-2, urokinase, tissue plasminogen activator, and tissue inhibitors of metalloproteinases. |
1996-11-20 |
2023-08-12 |
human |
| A R Sinning, C C Hewitt, R R Markwal. A subset of SBA lectin-binding proteins isolated from myocardial-conditioned media transforms cardiac endothelium into mesenchyme. Acta anatomica. vol 154. issue 2. 1996-09-23. PMID:8722510. |
in addition, a polyclonal antibody made against this subset of proteins is specific for the in situ particulate matrix and recognizes several proteins in conditioned medium and edta extracts. |
1996-09-23 |
2023-08-12 |
Not clear |
| A R Sinning, C C Hewitt, R R Markwal. A subset of SBA lectin-binding proteins isolated from myocardial-conditioned media transforms cardiac endothelium into mesenchyme. Acta anatomica. vol 154. issue 2. 1996-09-23. PMID:8722510. |
these results provide the most direct evidence to date that conditioned medium is equivalent to the hypothesized inductively active particulate matrix. |
1996-09-23 |
2023-08-12 |
Not clear |
| A R Sinning, C C Hewitt, R R Markwal. A subset of SBA lectin-binding proteins isolated from myocardial-conditioned media transforms cardiac endothelium into mesenchyme. Acta anatomica. vol 154. issue 2. 1996-09-23. PMID:8722510. |
in addition, the data provides evidence that conditioned medium can be used to identify the functional role of the components of the particulate matrix in mesenchyme formation. |
1996-09-23 |
2023-08-12 |
Not clear |
| J Taipale, J Saharinen, K Hedman, J Keski-Oj. Latent transforming growth factor-beta 1 and its binding protein are components of extracellular matrix microfibrils. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 44. issue 8. 1996-09-17. PMID:8756760. |
when isolated matrix components were immobilized on nitrocellulose and incubated with fibroblast conditioned medium, ltbp-1 from the medium associated with cellular fibronectin but not with heparan or chondroitin sulfate, vitronectin, tenascin, laminin, or collagen i or iv. |
1996-09-17 |
2023-08-12 |
human |
| R Felix, J Halasy-Nagy, A Wetterwald, M G Cecchini, H Fleisch, W Hofstette. Synthesis of membrane- and matrix-bound colony-stimulating factor-1 by cultured osteoblasts. Journal of cellular physiology. vol 166. issue 2. 1996-04-01. PMID:8591991. |
much smaller quantities of csf-1 were found in the matrix extract than in the conditioned medium. |
1996-04-01 |
2023-08-12 |
Not clear |
| Y Hakeda, H Kawaguchi, M Hurley, C C Pilbeam, C Abreu, T A Linkhart, S Mohan, M Kumegawa, L G Rais. Intact insulin-like growth factor binding protein-5 (IGFBP-5) associates with bone matrix and the soluble fragments of IGFBP-5 accumulated in culture medium of neonatal mouse calvariae by parathyroid hormone and prostaglandin E2-treatment. Journal of cellular physiology. vol 166. issue 2. 1996-04-01. PMID:8591997. |
igfbp-2 was partitioned between conditioned medium and bone and extracellular matrix (becm), while intact (31-kda) igfbp-5 was most abundant in becm extracts. |
1996-04-01 |
2023-08-12 |
mouse |
| F Roletto, A P Galvani, C Cristiani, B Valsasina, A Landonio, F Bertoler. Basic fibroblast growth factor stimulates hepatocyte growth factor/scatter factor secretion by human mesenchymal cells. Journal of cellular physiology. vol 166. issue 1. 1996-02-26. PMID:8557758. |
hgf/sf secretion was sustained after bfgf treatment for the following 72 h when increased amounts of hgf/sf were detected both in conditioned media as well as associated to the extracellular matrix. |
1996-02-26 |
2023-08-12 |
human |
| P Colburn, C P Dietrich, V Buonassis. Alterations of heparan sulfate moieties in cultured endothelial cells exposed to endotoxin. Archives of biochemistry and biophysics. vol 325. issue 1. 1996-02-16. PMID:8554337. |
in previous studies, we observed that exposure to endotoxin markedly reduces the level of heparan sulfate proteoglycans in the extracellular matrix of cultured endothelial cells and at the same time causes the accumulation of proteoglycans bearing glycosaminoglycan chains of reduced size in the conditioned medium (p. colburn, e. kobayashi, and v. buonassisi, 1994, j. |
1996-02-16 |
2023-08-12 |
Not clear |
| A L Schneyer, H A Hall, G Lambert-Messerlian, Q F Wang, P Sluss, W F Crowle. Follistatin-activin complexes in human serum and follicular fluid differ immunologically and biochemically. Endocrinology. vol 137. issue 1. 1996-02-05. PMID:8536619. |
in contrast, the activin binding peak in human serum elutes at an apparent mr of 60-70 kda, is no precipitated by anti-rhfs288 monoclonal antibodies, and is weakly bound by sulfate cellufine matrix, characteristics shared by rhfs315 conditioned medium. |
1996-02-05 |
2023-08-12 |
human |
| G Salvatori, L Lattanzi, M Coletta, S Aguanno, E Vivarelli, R Kelly, G Ferrari, A J Harris, F Mavilio, M Molinar. Myogenic conversion of mammalian fibroblasts induced by differentiating muscle cells. Journal of cell science. vol 108 ( Pt 8). 1995-12-15. PMID:7593314. |
myogenic conversion ranged from 1 to 10% of the 10t1/2 cell population and required close cell interaction between the different cells types: it was not induced by conditioned medium or extracellular matrix deposited by c2c12 cells. |
1995-12-15 |
2023-08-12 |
mouse |
| M Zanni, A Tamburro, D Rotili. IL-1 beta and TGF-beta 1 modulate the sulphation grade of chondro-disaccharides in porcine articular cartilage: a capillary electrophoresis study. Journal of lipid mediators and cell signalling. vol 12. issue 1. 1995-11-14. PMID:7551687. |
glycosaminoglycans (gags) of conditioned medium and extracellular matrix proteoglycans were digested by chondroitin abc and ac lyase, suggesting that chondroitin sulphate (cs) is the major gag present (80-90%). |
1995-11-14 |
2023-08-12 |
Not clear |
| M Hormia, J Falk-Marzillier, G Plopper, R N Tamura, J C Jones, V Quarant. Rapid spreading and mature hemidesmosome formation in HaCaT keratinocytes induced by incubation with soluble laminin-5r. The Journal of investigative dermatology. vol 105. issue 4. 1995-11-14. PMID:7561158. |
electron microscopy of hacat cells spread by incubation in 804g conditioned medium, but not control medium, revealed mature hemidesmosomes after 24 h. rapid spreading was also observed in wells precoated with 804g conditioned medium or 804g cell-deposited matrix, but not with fibronectin, vitronectin, or laminin-1. |
1995-11-14 |
2023-08-12 |
Not clear |