| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jiraporn Kantapan, Nampeung Anukul, Nipapan Leetrakool, Gwenaël Rolin, Jackie Vergote, Nathupakorn Dechsup. Iron-Quercetin Complex Preconditioning of Human Peripheral Blood Mononuclear Cells Accelerates Angiogenic and Fibroblast Migration: Implications for Wound Healing. International journal of molecular sciences. vol 22. issue 16. 2021-09-13. PMID:34445558. |
the conditioned medium obtained from ironq-treated pbmcs contained high levels of interleukin 8 (il-8), il-10, urokinase-type-plasminogen-activator (upa), matrix metalloproteinases-9 (mmp-9), and tumor necrosis factor-alpha (tnf-α), as well as augmented migration and capillary network formation of huvecs and fibroblast cells, in vitro. |
2021-09-13 |
2023-08-13 |
human |
| Reaz Vawda, Anna Badner, James Hong, Mirriam Mikhail, Rachel Dragas, Kristiana Xhima, Alejandro Jose, Michael G Fehling. Harnessing the Secretome of Mesenchymal Stromal Cells for Traumatic Spinal Cord Injury: Multicell Comparison and Assessment of In Vivo Efficacy. Stem cells and development. vol 29. issue 22. 2021-09-03. PMID:32962528. |
in this study, we compare the efficacy of intravenously delivered concentrated conditioned media (cm) from human umbilical cord matrix cells (hucmcs), bone marrow mesenchymal stromal cells, as well as newborn and adult fibroblasts in a rat model of moderately severe cervical clip compression/contusion injury (c7--t1, 35 g). |
2021-09-03 |
2023-08-13 |
human |
| Honing Huang, Tomomi Nakamura, Toshinori Yasuzawa, Shigeru Ueshim. Effects of Coriandrum sativum on Migration and Invasion Abilities of Cancer Cells. Journal of nutritional science and vitaminology. vol 66. issue 5. 2021-08-25. PMID:33132351. |
the treatment of cancer cells with coriander extract significantly reduced both matrix metalloproteinase 2 (mmp-2) and urokinase-type plasminogen activator (u-pa) activities, which were involved in cell migration and invasion, in their conditioned media. |
2021-08-25 |
2023-08-13 |
mouse |
| Alan Tin-Lun Lam, Alison P Lee, Premkumar Jayaraman, Kah Yong Tan, Deepak Raghothaman, Hsueh Lee Lim, He Cheng, Lihan Zhou, Andy Hee-Meng Tan, Shaul Reuveny, Steve O. Multiomics analyses of cytokines, genes, miRNA, and regulatory networks in human mesenchymal stem cells expanded in stirred microcarrier-spinner cultures. Stem cell research. vol 53. 2021-06-30. PMID:33676128. |
importantly, mc-spinner cultures and conditioned medium showed increased expression of factors that possibly enhance pathways of extracellular matrix dynamics, cellular metabolism, differentiation potential, immunoregulatory function, and wound healing. |
2021-06-30 |
2023-08-13 |
human |
| Chrystelle V Garat, Susan M Majka, Timothy M Sullivan, Joseph T Crossno, Jane E B Reusch, Dwight J Klem. CREB depletion in smooth muscle cells promotes medial thickening, adventitial fibrosis and elicits pulmonary hypertension. Pulmonary circulation. vol 10. issue 2. 2021-06-16. PMID:32313640. |
isolated murine creb-null smooth muscle cells exhibited serum-independent proliferation and hypertrophy in vitro and medium conditioned by creb-null smooth muscle cells stimulated proliferation and expression of extracellular matrix proteins by adventitial fibroblasts. |
2021-06-16 |
2023-08-13 |
mouse |
| Federica Finetti, Irene Schiavo, Jasmine Ercoli, Alessia Zotta, Enrica Boda, Saverio Francesco Retta, Lorenza Trabalzin. KRIT1 loss-mediated upregulation of NOX1 in stromal cells promotes paracrine pro-angiogenic responses. Cellular signalling. vol 68. 2021-06-09. PMID:31917192. |
furthermore and importantly, we show that conditioned media from krit1 null fibroblasts induce proliferation, migration, matrix metalloproteinase 2 (mmp2) activation and ve-cadherin redistribution in wild type human endothelial cells. |
2021-06-09 |
2023-08-13 |
human |
| Weijing Han, Rania El Botty, Elodie Montaudon, Laurent Malaquin, Frederic Deschaseaux, Nicolas Espagnolle, Elisabetta Marangoni, Paul Cottu, Gérard Zalcman, Maria Carla Parrini, Franck Assayag, Luc Sensebe, Pascal Silberzan, Anne Vincent-Salomon, Guillaume Dutertre, Sergio Roman-Roman, Stephanie Descroix, Jacques Camoni. In vitro bone metastasis dwelling in a 3D bioengineered niche. Biomaterials. vol 269. 2021-05-24. PMID:33421710. |
to do so we first 3d printed a bone scaffold that reproduces the trabecular architecture and that can be conditioned with osteoblast-like cells, a collagen matrix, and mineralized calcium. |
2021-05-24 |
2023-08-13 |
Not clear |
| Jun Su Kim, Il-Hoon Cho, Kyung-Hee Kim, Young Sun Hwan. Identification of galectin‑10 as a biomarker for periodontitis based on proteomic analysis of gingival crevicular fluid. Molecular medicine reports. vol 23. issue 2. 2021-05-04. PMID:33300083. |
the levels of interleukin‑8, matrix metalloproteinase 9 and c‑reactive protein were increased in the conditioned media (cm) of rgal‑10‑treated gingival fibroblasts. |
2021-05-04 |
2023-08-13 |
Not clear |
| Seung-Woo Lee, Hyun-Kyung Kim, Purevjargal Naidansuren, Kyung A Ham, Hong Seok Choi, Hyun-Young Ahn, Myungshin Kim, Dong Hoon Kang, Sang Won Kang, Young Ae Jo. Peroxidasin is essential for endothelial cell survival and growth signaling by sulfilimine crosslink-dependent matrix assembly. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 34. issue 8. 2021-02-26. PMID:32543734. |
conditioned medium (cm) containing wild-type pxdn restored the proliferation of pxdn-depleted cells, but cm containing mutant pxdn with deletion of either n-terminal extracellular matrix (ecm) motifs or peroxidase domain failed to restore pxdn function. |
2021-02-26 |
2023-08-13 |
Not clear |
| Shuangpeng Jiang, Guangzhao Tian, Xu Li, Zhen Yang, Fuxin Wang, Zhuang Tian, Bo Huang, Fu Wei, Kangkang Zha, Zhiqiang Sun, Xiang Sui, Shuyun Liu, Weimin Guo, Quanyi Gu. Research Progress on Stem Cell Therapies for Articular Cartilage Regeneration. Stem cells international. vol 2021. 2021-02-26. PMID:33628274. |
the application of stem cell derivatives, such as conditioned media, extracellular vesicles, and extracellular matrix, is an extension of stem cell paracrine theory. |
2021-02-26 |
2023-08-13 |
Not clear |
| Kyung-Eun Lee, Youn-Hwa Nho, Seok Kyun Yun, Sung-Min Park, Seunghyun Kang, Hyeonju Ye. Caviar Extract and Its Constituent DHA Inhibits UVB-Irradiated Skin Aging by Inducing Adiponectin Production. International journal of molecular sciences. vol 21. issue 9. 2021-02-22. PMID:32403430. |
in addition, the mrna expression levels of matrix metalloproteinase-1 (mmp-1) were decreased in uvb-irradiated hs68 fibroblasts that were cultured in conditioned medium from caviar extract or dha-treated differentiated adipocytes. |
2021-02-22 |
2023-08-13 |
Not clear |
| Debolina Chakraborty, K R Ethiraj, N Chandrasekaran, Amitava Mukherje. Mitigating the toxic effects of CdSe quantum dots towards freshwater alga Scenedesmus obliquus: Role of eco-corona. Environmental pollution (Barking, Essex : 1987). vol 270. 2021-01-21. PMID:33213955. |
in the present study, lake water medium conditioned with exudate secreted by scenedesmus obliquus was utilized as an eco-corona forming matrix. |
2021-01-21 |
2023-08-13 |
Not clear |
| Deepti Kannan, Daniel J Sharpe, Thomas D Swinburne, David J Wale. Optimal dimensionality reduction of Markov chains using graph transformation. The Journal of chemical physics. vol 153. issue 24. 2020-12-31. PMID:33380101. |
inversion of the weighted-mfpt matrix, which is better conditioned than the matrices that must be inverted in alternative dimensionality reduction schemes, then yields the optimal reduced markov chain. |
2020-12-31 |
2023-08-13 |
Not clear |
| Tamara Rosell-García, Fernando Rodríguez-Pascua. Boosting collagen deposition with a lysyl oxidase/bone morphogenetic protein-1 cocktail. Methods in cell biology. vol 156. 2020-12-24. PMID:32222222. |
incubation of fibroblast monolayers with these conditioned media strongly increases the capacity of these cells to deposit collagen onto the insoluble extracellular matrix. |
2020-12-24 |
2023-08-13 |
human |
| Annett Klinder, Sophie Kussauer, Bettina Hiemer, Andreas Wree, Rainer Bader, Anika Jonitz-Heinck. Influence of Conditioned Media on the Re-Differentiation Capacity of Human Chondrocytes in 3D Spheroid Cultures. Journal of clinical medicine. vol 9. issue 9. 2020-10-27. PMID:32872610. |
media were conditioned by incubation of 200 mg/ml vital or devitalized cartilage matrix in growth media over 35 days. |
2020-10-27 |
2023-08-13 |
human |
| Thi Yen Loan Le, Hilda A Pickett, Andrian Yang, Joshua W K Ho, Sujitha Thavapalachandran, Sindhu Igoor, Sile F Yang, Melad Farraha, Holly K Voges, James E Hudson, Cristobal G Dos Remedios, Tracy M Bryan, Eddy Kizana, James J H Chon. Enhanced cardiac repair by telomerase reverse transcriptase over-expression in human cardiac mesenchymal stromal cells. Scientific reports. vol 9. issue 1. 2020-10-26. PMID:31332256. |
mass spectrometry on htert + pdgfrα + cmscs conditioned media showed increased proteins associated with matrix modulation, angiogenesis, cell proliferation/survival/adhesion and innate immunity function. |
2020-10-26 |
2023-08-13 |
human |
| Niamh O'Halloran, Sonja Khan, Katie Gilligan, Roisin Dwyer, Michael Kerin, Aoife Lower. Oncological Risk in Autologous Stem Cell Donation for Novel Tissue-Engineering Approaches to Postmastectomy Breast Regeneration. Breast cancer : basic and clinical research. vol 13. 2020-09-30. PMID:31555047. |
a number of cytokines were detected in the cell conditioned media of adscs from different sources, including matrix metalloproteinase-2 (mmp-2), which was detected at higher levels in the secretome of adscs from breast cancer patients compared with noncancer controls. |
2020-09-30 |
2023-08-13 |
Not clear |
| Sarah Libring, Aparna Shinde, Monica K Chanda, Maryam Nuru, Heather George, Aya M Saleh, Ammara Abdullah, Tamara L Kinzer-Ursem, Sarah Calve, Michael K Wendt, Luis Solori. The Dynamic Relationship of Breast Cancer Cells and Fibroblasts in Fibronectin Accumulation at Primary and Metastatic Tumor Sites. Cancers. vol 12. issue 5. 2020-09-28. PMID:32429591. |
in the former, fibroblasts conditioned by bc cultures with high emp resulted in the largest fn matrix accumulation. |
2020-09-28 |
2023-08-13 |
Not clear |
| Sarah Libring, Aparna Shinde, Monica K Chanda, Maryam Nuru, Heather George, Aya M Saleh, Ammara Abdullah, Tamara L Kinzer-Ursem, Sarah Calve, Michael K Wendt, Luis Solori. The Dynamic Relationship of Breast Cancer Cells and Fibroblasts in Fibronectin Accumulation at Primary and Metastatic Tumor Sites. Cancers. vol 12. issue 5. 2020-09-28. PMID:32429591. |
in contrast, mesenchymal bc cells produced extracellular vesicles (ev) that resulted in the highest levels of matrix formation by conditioned fibroblasts. |
2020-09-28 |
2023-08-13 |
Not clear |
| Mohsen Abbasi-Kangevari, Seyyed-Hadi Ghamari, Fahimeh Safaeinejad, Soheyl Bahrami, Hassan Nikneja. Potential Therapeutic Features of Human Amniotic Mesenchymal Stem Cells in Multiple Sclerosis: Immunomodulation, Inflammation Suppression, Angiogenesis Promotion, Oxidative Stress Inhibition, Neurogenesis Induction, MMPs Regulation, and Remyelination Stimulation. Frontiers in immunology. vol 10. 2020-07-21. PMID:30842772. |
considering the mentioned evidences, we hypothesized here that hamscs and their conditioned medium could be of therapeutic value in ms therapy due to their unique properties, including immunomodulation and inflammation suppression; angiogenesis promotion; oxidative stress inhibition; neurogenesis induction and neuroprotection; matrix metalloproteinases regulation; and remyelination stimulation. |
2020-07-21 |
2023-08-13 |
human |