| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sridhar Natesan, Greg E Reckless, Karen B L Barlow, José N Nobrega, Shitij Kapu. Evaluation of N-desmethylclozapine as a potential antipsychotic--preclinical studies. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 7. 2007-08-31. PMID:17164815. |
the comparison was carried out using: brain d(2) and 5-ht(2) receptor occupancy; animal models predictive of antipsychotic efficacy (amphetamine-induced hyperlocomotion (ail) and conditioned avoidance response (car) models); measures predictive of side effects (catalepsy and prolactin elevation); and molecular markers predictive of antipsychotic action (striatal fos induction). |
2007-08-31 |
2023-08-12 |
Not clear |
| Sabiha K Barot, Susan M Ferguson, John F Neumaie. 5-HT(1B) receptors in nucleus accumbens efferents enhance both rewarding and aversive effects of cocaine. The European journal of neuroscience. vol 25. issue 10. 2007-08-17. PMID:17509084. |
in this study we further examined the contribution of 5-ht(1b) receptors on the effect of cocaine under conditions intended to selectively influence either conditioned place preference or avoidance (cpp or cpa, respectively). |
2007-08-17 |
2023-08-12 |
rat |
| Weiqing Ji, Nobuo Sug. Serotonergic modulation of plasticity of the auditory cortex elicited by fear conditioning. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 18. 2007-06-06. PMID:17475799. |
we applied 5-ht, an agonist (alpha-methyl-5-ht), or an antagonist (ritanserin) of 5-ht(2a) receptors to the primary auditory cortex and discovered the following drug effects: (1) 5-ht had no effect on the conditioned heart rate change, although it reduced the auditory responses; (2) 4 mm 5-ht augmented the subthreshold bf shifts, whereas 20 mm 5-ht did not; (3) 20 mm 5-ht reduced the long-term bf shifts and changed them into short-term; (4) alpha-methyl-5-ht increased the auditory responses and augmented the subthreshold bf shifts as well as the long-term bf shifts; (5) in contrast, ritanserin reduced the auditory responses and reversed the direction of the bf shifts. |
2007-06-06 |
2023-08-12 |
Not clear |
| Kevin F Foley, Cristen Pantano, Allison Ciolino, Gary M Maw. IFN-gamma and TNF-alpha decrease serotonin transporter function and expression in Caco2 cells. American journal of physiology. Gastrointestinal and liver physiology. vol 292. issue 3. 2007-04-24. PMID:17170025. |
application of the conditioned medium caused a decrease in fluoxetine-sensitive [(3)h]5-ht uptake. |
2007-04-24 |
2023-08-12 |
human |
| Carlos Eduardo Macedo, Raquel Chacon Ruiz Martinez, Lucas Albrechet-Souza, Victor Alejandro Molina, Marcus Lira Brandã. 5-HT2- and D1-mechanisms of the basolateral nucleus of the amygdala enhance conditioned fear and impair unconditioned fear. Behavioural brain research. vol 177. issue 1. 2007-03-27. PMID:17126419. |
based on this, we examined the effects of ketanserin and sch-23390, antagonists of the 5ht(2) and d(1) receptors, respectively, on the conditioned and unconditioned fear elicited by ic stimulation with smc. |
2007-03-27 |
2023-08-12 |
Not clear |
| Yukio Takamatsu, Hideko Yamamoto, Yasukazu Ogai, Yoko Hagino, Athina Markou, Kazutaka Iked. Fluoxetine as a potential pharmacotherapy for methamphetamine dependence: studies in mice. Annals of the New York Academy of Sciences. vol 1074. 2007-01-10. PMID:17105925. |
interestingly, the rewarding effects of cocaine are retained in dopamine transporter (dat) knockout (ko) mice, while serotonin transporter (sert) and dat double ko mice do not exhibit conditioned place preference (cpp) to cocaine. |
2007-01-10 |
2023-08-12 |
mouse |
| Takeshi Inoue, Shin Nakagawa, Takeshi Izumi, Yuji Kitaichi, Tsukasa Koyam. Effect of combined treatment with noradrenaline and serotonin reuptake inhibitors on conditioned freezing. European journal of pharmacology. vol 540. issue 1-3. 2006-12-11. PMID:16714013. |
effect of combined treatment with noradrenaline and serotonin reuptake inhibitors on conditioned freezing. |
2006-12-11 |
2023-08-12 |
rat |
| Małgorzata Lehner, Ewa Taracha, Anna Skórzewska, Piotr Maciejak, Aleksandra Wisłowska-Stanek, Małgorzata Zienowicz, Janusz Szyndler, Andrzej Bidziński, Adam Płaźni. Behavioral, immunocytochemical and biochemical studies in rats differing in their sensitivity to pain. Behavioural brain research. vol 171. issue 2. 2006-09-25. PMID:16707171. |
the different patterns of behavioral coping strategies (a conditioned freezing response and ultrasonic vocalization) were analyzed in animals differing in their response to the acute painful stimulation, a foot-shock (hs: high sensitivity rats, ls: low sensitivity rats, and ms: medium sensitivity rats, according to their behavior in the flinch-jump pre-test), and correlated with plasma corticosterone levels, expression of c-fos protein, and distribution of 5-ht innervation, in different brain structures. |
2006-09-25 |
2023-08-12 |
rat |
| Saak V Ovsepian, Nikolai P Vesselki. Serotonergic modulation of synaptic transmission and action potential firing in frog motoneurons. Brain research. vol 1102. issue 1. 2006-09-19. PMID:16806121. |
contrasting to dr evoked responses 5-ht did not affect the descending monosynaptic epsp conditioned by ventrolateral column (vlc) stimulation. |
2006-09-19 |
2023-08-12 |
Not clear |
| Petr Zach, Zach Petr, Jiri Krivanek, Krivanek Jiri, Karel Vales, Vales Kare. Serotonin and dopamine in the parabrachial nucleus of rats during conditioned taste aversion learning. Behavioural brain research. vol 170. issue 2. 2006-09-14. PMID:16603254. |
serotonin and dopamine in the parabrachial nucleus of rats during conditioned taste aversion learning. |
2006-09-14 |
2023-08-12 |
rat |
| Petr Zach, Zach Petr, Jiri Krivanek, Krivanek Jiri, Karel Vales, Vales Kare. Serotonin and dopamine in the parabrachial nucleus of rats during conditioned taste aversion learning. Behavioural brain research. vol 170. issue 2. 2006-09-14. PMID:16603254. |
a microdialysis technique was used to monitor changes in serotonin (5-ht), 5-hydroxyindole acetic acid (5-hiaa) and dopamine (da) in the extracellular space of the parabrachial nucleus (pbn) of rats to estimate the contribution of these neurotransmitter systems to the acquisition of conditioned taste aversion (cta). |
2006-09-14 |
2023-08-12 |
rat |
| G F Molodtsov. [Different roles of dopamine and serotonin in conditioned passive avoidance response of rats]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 56. issue 2. 2006-07-12. PMID:16756132. |
[different roles of dopamine and serotonin in conditioned passive avoidance response of rats]. |
2006-07-12 |
2023-08-12 |
rat |
| G F Molodtsov. [Different roles of dopamine and serotonin in conditioned passive avoidance response of rats]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 56. issue 2. 2006-07-12. PMID:16756132. |
deamination of dopamine and serotonin by monoamine oxidase was studied in the prefrontal cortex, striatum, hippocampus and amygdaloid complex of the brain of rats during retrieval of conditioned passive avoidance response. |
2006-07-12 |
2023-08-12 |
rat |
| XiaoBai Li, Takeshi Inoue, Tomohiro Abekawa, ShiMin Weng, Shin Nakagawa, Takeshi Izumi, Tsukasa Koyam. 5-HT1A receptor agonist affects fear conditioning through stimulations of the postsynaptic 5-HT1A receptors in the hippocampus and amygdala. European journal of pharmacology. vol 532. issue 1-2. 2006-06-02. PMID:16460727. |
in the present study, we investigated the effects of bilateral microinjections of flesinoxan, a selective 5-ht(1a) receptor agonist, into the hippocampus, amygdala and medial prefrontal cortex on the expression of contextual conditioned freezing and the defecation induced by conditioned fear stress in rats. |
2006-06-02 |
2023-08-12 |
rat |
| Linda A Parker, Magdalena Kwiatkowska, Raphael Mechoula. Delta-9-tetrahydrocannabinol and cannabidiol, but not ondansetron, interfere with conditioned retching reactions elicited by a lithium-paired context in Suncus murinus: An animal model of anticipatory nausea and vomiting. Physiology & behavior. vol 87. issue 1. 2006-03-09. PMID:16197970. |
on the other hand, pretreatment with a dose of ondansetron (a 5-ht(3) antagonist) that interferes with acute vomiting in this species, did not suppress the expression of conditioned retching during re-exposure to the lithium-paired context. |
2006-03-09 |
2023-08-12 |
Not clear |
| Kevin B Freeman, Kenner C Rice, Anthony L Rile. Assessment of monoamine transporter inhibition in the mediation of cocaine-induced conditioned taste aversion. Pharmacology, biochemistry, and behavior. vol 82. issue 3. 2006-03-02. PMID:16337262. |
using the conditioned taste aversion (cta) preparation, the present study examined the role of monoamine uptake inhibition in cocaine's aversive effects by comparing cocaine to three reuptake inhibitors with relative specificity for the transporters of dopamine (dat; gbr 12909), norepinephrine (net; desipramine) and serotonin (sert; clomipramine). |
2006-03-02 |
2023-08-12 |
rat |
| G F Molodtsov. Metabolism and receptor binding of serotonin in brain structures during performance of a conditioned passive avoidance response. Neuroscience and behavioral physiology. vol 35. issue 7. 2006-03-02. PMID:16433063. |
metabolism and receptor binding of serotonin in brain structures during performance of a conditioned passive avoidance response. |
2006-03-02 |
2023-08-12 |
rat |
| G F Molodtsov. Metabolism and receptor binding of serotonin in brain structures during performance of a conditioned passive avoidance response. Neuroscience and behavioral physiology. vol 35. issue 7. 2006-03-02. PMID:16433063. |
the levels of serotonin and its metabolite 5-hydroxyindoleacetic acid, monoamine oxidase activity, and the specific binding of the radioligand [3h]serotonin were measured in the prefrontal cortex, striatum, amygdaloid complex, hippocampus, and periacqueductal gray matter of the midbrain in rats at different time points after training to a conditioned passive avoidance reaction. |
2006-03-02 |
2023-08-12 |
rat |
| G F Molodtsov. Metabolism and receptor binding of serotonin in brain structures during performance of a conditioned passive avoidance response. Neuroscience and behavioral physiology. vol 35. issue 7. 2006-03-02. PMID:16433063. |
the involvement of the brain serotoninergic system in the process of performing the conditioned reaction was found to demonstrate a spatial-structural selectivity: the metabolism and receptor binding of serotonin changed in the amygdaloid complex, periacqueductal gray matter, and the striatum, while no changes were seen in the hippocampus or prefrontal cortex. |
2006-03-02 |
2023-08-12 |
rat |
| Ellen A Walker, Stephen J Kohut, Richard W Hass, Edward K Brown, Anupama Prabandham, Timothy Lefeve. Selective and nonselective serotonin antagonists block the aversive stimulus properties of MK212 and m-chlorophenylpiperazine (mCPP) in mice. Neuropharmacology. vol 49. issue 8. 2006-01-17. PMID:16165167. |
in the present study, the capacities of two 5-ht(2c) agonists, mk212 and mcpp, to produce conditioned taste aversions in mice were evaluated. |
2006-01-17 |
2023-08-12 |
mouse |