| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cassandre Morel, Ines Martinez Sanchez, Yamina Cherifi, Nicolas Chartrel, Rochellys Diaz Heijt. Perturbation of maternal gut microbiota in mice during a critical perinatal window influences early neurobehavioral outcomes in offspring. Neuropharmacology vol issue 2023 36870672 |
this behavioral phenotype of exposed juvenile males was associated with reduced gene expression of the oxytocin receptor (oxtr) and several tight-junction proteins in the prefrontal cortex, a key region involved in the regulation of social and emotional behavior, as well as a mild inflammatory response in the colon. |
2023-03-04 |
2023-03-06 |
mouse |
| Birgit Ludwig, Laura Carlberg, Klemens Kienesberger, Patrick Swoboda, Marleen M M Swoboda, Alexandra Bernegger, Romina Koller, Michelle Inaner, Monika Fuxj\\xc3\\xa4ger, Melanie Zotter, Nicolas Schmelzle, Birgit Senft, Lisa Meisner, Daniela Fischer-Hansal, Jasmin Huber, Silvia Schoenthaler, Nestor D Kapusta, Helmuth Haslacher, Martin Aigner, Andreas Weinhaeusel, Siegfried Kasper, Alexandra Schosse. Oxytocin receptor gene methylation as a molecular marker for severity of depressive symptoms in affective disorder patients. BMC psychiatry vol 22 issue 1 2022 35672748 |
both preclinical and clinical studies point to an increased methylation status of the oxytocin receptor (oxtr) promoter region with concomitant deficits in social, cognitive and emotional functioning. |
2022-06-07 |
2023-01-27 |
Not clear |
| Jane Kohlhoff, Sara Cibralic, David Hawes, Valsamma Eape. Oxytocin receptor gene (OXTR) polymorphisms and social, emotional and behavioral functioning in children and adolescents: a systematic narrative review. Neuroscience and biobehavioral reviews vol issue 2022 35149102 |
oxytocin receptor gene (oxtr) polymorphisms and social, emotional and behavioral functioning in children and adolescents: a systematic narrative review. |
2022-02-12 |
2023-01-27 |
Not clear |
| Jane Kohlhoff, Sara Cibralic, David Hawes, Valsamma Eape. Oxytocin receptor gene (OXTR) polymorphisms and social, emotional and behavioral functioning in children and adolescents: a systematic narrative review. Neuroscience and biobehavioral reviews vol issue 2022 35149102 |
results suggest that oxtr polymorphisms are associated with social, emotional or behavioural functioning in children and adolescents. |
2022-02-12 |
2023-01-27 |
Not clear |
| Luoyang Ding, Shane K Maloney, Mengzhi Wang, Jennifer Rodger, Lianmin Chen, Dominique Blach. Association between temperament related traits and single nucleotide polymorphisms in the serotonin and oxytocin systems in Merino sheep. Genes, brain, and behavior vol 20 issue 3 2021 33161622 |
using ewes from the university of western australia temperament flock, which has been selected on emotional reactivity for more than 20 generations, eight snps (rs107856757, rs107856818, rs107856856 and rs107857156 in tph2, rs20917091 in slc6a4, rs17196799 and rs17193181 in htr2a, and rs17664565 in oxtr) were found to be distributed differently between calm and nervous sheep. |
2021-11-09 |
2023-01-26 |
Not clear |
| Amy L Byrd, Irene Tung, Stephen D Manuck, Vera Vine, Michelle Horner, Alison E Hipwell, Stephanie D Step. An interaction between early threat exposure and the oxytocin receptor in females: Disorder-specific versus general risk for psychopathology and social-emotional mediators. Development and psychopathology vol 33 issue 4 2021 32693857 |
the current study utilized a prospective, longitudinal sample of females (n = 2,020) to examine: (a) whether the interaction between early threat exposure and oxtr variation (rs53576, rs2254298) confers risk for disorder-specific outcomes (depression, anxiety, borderline and antisocial personality disorders) and/or general psychopathology in early adulthood; and (b) whether social-emotional deficits (emotion dysregulation, callousness, attachment quality) during adolescence constitute mediating mechanisms. |
2021-11-04 |
2023-01-26 |
Not clear |
| Laura Lemel, Katarzyna Nie\\xc5\\x9bcierowicz, M Dolores Garc\\xc3\\xada-Fern\\xc3\\xa1ndez, Leonardo Darr\\xc3\\xa9, Thierry Durroux, Marta Busnelli, Myl\\xc3\\xa8ne Pezet, Fabrice R\\xc3\\xa9beill\\xc3\\xa9, Juliette Jouhet, Bernard Mouillac, Carmen Domene, Bice Chini, Vadim Cherezov, Christophe J Morea. The ligand-bound state of a G protein-coupled receptor stabilizes the interaction of functional cholesterol molecules. Journal of lipid research vol 62 issue 2021 33647276 |
the oxytocin receptor (oxtr) is involved in parturition and lactation of mammals and in their emotional and social behaviors. |
2021-10-12 |
2023-01-26 |
Not clear |
| Jin Liu, Siyuan Shang, Meng Pei, Yanjie S. Influence of Two Single-Nucleotide Polymorphisms of the Oxytocin Receptor Gene (OXTR) on Empathy: the Mediation Role of a Primary Emotion, CARE. Journal of molecular neuroscience : MN vol 71 issue 2 2021 32607757 |
influence of two single-nucleotide polymorphisms of the oxytocin receptor gene (oxtr) on empathy: the mediation role of a primary emotion, care. |
2021-10-05 |
2023-01-26 |
human |
| Ling Huang, Chengxing Duan, Xiuwen Xia, Huaifu Wang, Yili Wang, Zhanqiong Zhong, Baojia Wang, Weijun Ding, Youjun Yan. Commensal microbe-derived propionic acid mediates juvenile social isolation-induced social deficits and anxiety-like behaviors. Brain research bulletin vol 166 issue 2021 33279588 |
collectively, our findings reveal that juvenile social experience regulates prefrontal cortical oxtr expression through gut microbiota-produced pa and that is essential for normal social and emotional behaviors, thus providing a cellular and molecular context to understand the consequences of juvenile social deprivation. |
2021-08-11 |
2023-01-26 |
mouse |
| Hongjian Cao, Nan Zhou, Esther M Leerkes, Jinni S. The etiology of maternal postpartum depressive symptoms: Childhood emotional maltreatment, couple relationship satisfaction, and genes. Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43) vol 35 issue 1 2021 32463265 |
using longitudinal data from 198 primiparous mothers, we tested a biopsychosocial model for the etiology of maternal postpartum depressive symptoms that integrated childhood emotional maltreatment, couple relationship satisfaction, and oxytocin and dopamine d4 receptor genes (i.e., oxtr rs53576 and drd4). |
2021-06-14 |
2023-01-26 |
Not clear |
| Hongjian Cao, Nan Zhou, Esther M Leerkes, Jinni S. The etiology of maternal postpartum depressive symptoms: Childhood emotional maltreatment, couple relationship satisfaction, and genes. Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43) vol 35 issue 1 2021 32463265 |
results indicate (a) two indirect effects from childhood emotional maltreatment and drd4 to depressive symptoms at 1 year postpartum through couple relationship satisfaction at 6 months postpartum; (b) an interactive effect between drd4 and couple relationship satisfaction at 6 months postpartum in predicting depressive symptoms at 1 year postpartum, which is in concert with the differential susceptibility hypotheses; and (c) no mediating effects or moderating effects (after adjusting for multiple testing with bonferroni correction) involving oxtr rs53576. |
2021-06-14 |
2023-01-26 |
Not clear |
| Gin S Malhi, Pritha Das, Tim Outhred, Carol Dobson-Stone, Erica Bell, Danielle Gessler, Richard Bryant, Zola Manni. Interactions of OXTR rs53576 and emotional trauma on hippocampal volumes and perceived social support in adolescent girls. Psychoneuroendocrinology vol 115 issue 2021 32199286 |
interactions of oxtr rs53576 and emotional trauma on hippocampal volumes and perceived social support in adolescent girls. |
2021-04-19 |
2023-01-26 |
Not clear |
| Marina Butovskaya, Victoria Rostovtseva, Polina Butovskaya, Valentina Burkova, Daria Dronova, Vasilisa Filatova, Eugenia Sukhodolskaya, Vasiliy Vasiliev, Tania Mesa, Araceli Rosa, Oleg Lazebn. Oxytocin receptor gene polymorphism (rs53576) and digit ratio associates with aggression: comparison in seven ethnic groups. Journal of physiological anthropology vol 39 issue 1 2021 32795360 |
the specific role of the oxytocin receptor (oxtr) gene polymorphisms in emotional support seeking, related to social norms and culturally normative behavior, has been discussed in several studies. |
2021-02-02 |
2023-01-26 |
Not clear |
| Friedrich Meixner, Christian Montag, Cornelia Herber. Affective Language, Interpretation Bias and Its Molecular Genetic Variations: Exploring the Relationship Between Genetic Variations of the OXTR Gene (rs53576 and rs2268498) and the Emotional Evaluation of Words Related to the Self or the Other. Frontiers in psychology vol 10 issue 2020 30873056 |
affective language, interpretation bias and its molecular genetic variations: exploring the relationship between genetic variations of the oxtr gene (rs53576 and rs2268498) and the emotional evaluation of words related to the self or the other. |
2020-10-01 |
2023-01-26 |
human |
| Jing Zhao, Yafang Yang, Xiaohan Li, Linfeng Zheng, Mengying Xue, Mengfei Zhang, Chunlan Wang, Rongjun Yu, Pingyuan Gon. OXTR rs53576 polymorphism impacts interpersonal adaptability: Dispositional forgiveness as a mediator. Psychoneuroendocrinology vol 103 issue 2020 30605805 |
polymorphisms in the oxytocin receptor (oxtr) gene have been shown to be related to individual differences in social skills that are important for building and maintaining social relationships, such as the capability to efficiently process social information and regulate emotions. |
2020-04-23 |
2023-01-26 |
Not clear |
| Kateryna Savelieva, Mirka Hintsanen, Henrik Dobewall, Markus Jokela, Laura Pulkki-R\\xc3\\xa5back, Marko Elovainio, Ilkka Sepp\\xc3\\xa4l\\xc3\\xa4, Terho Lehtim\\xc3\\xa4ki, Olli Raitakari, Liisa Keltikangas-J\\xc3\\xa4rvine. The role of oxytocinergic genes in the intergenerational transmission of parent-child relationship qualities. Hormones and behavior vol 114 issue 2020 31202819 |
g1 maternal emotional warmth was associated with higher g2 emotional warmth among g2 participants with the oxtr rs53576 aa/ag genotype, but not among those with the gg genotype. |
2020-02-03 |
2023-01-26 |
human |
| Patrick Vizeli, Matthias E Liecht. Oxytocin receptor gene variations and socio-emotional effects of MDMA: A pooled analysis of controlled studies in healthy subjects. PloS one vol 13 issue 6 2019 29912955 |
genetic variants, such as single-nucleotide polymorphisms (snps), of the oxytocin receptor (oxtr) may influence the emotional and social effects of mdma in humans. |
2019-04-11 |
2023-01-26 |
human |
| Patrick Vizeli, Matthias E Liecht. Oxytocin receptor gene variations and socio-emotional effects of MDMA: A pooled analysis of controlled studies in healthy subjects. PloS one vol 13 issue 6 2019 29912955 |
the effects of common genetic variants of the oxtr (rs53576, rs1042778, and rs2254298 snps) on the emotional, empathogenic, and prosocial effects of mdma were characterized in up to 132 healthy subjects in a pooled analysis of eight double-blind, placebo-controlled studies. |
2019-04-11 |
2023-01-26 |
human |
| Catherine Maud, Joanne Ryan, Jennifer E McIntosh, Craig A Olsso. The role of oxytocin receptor gene (OXTR) DNA methylation (DNAm) in human social and emotional functioning: a systematic narrative review. BMC psychiatry vol 18 issue 1 2019 29843655 |
the role of oxytocin receptor gene (oxtr) dna methylation (dnam) in human social and emotional functioning: a systematic narrative review. |
2019-03-01 |
2023-01-26 |
human |
| Catherine Maud, Joanne Ryan, Jennifer E McIntosh, Craig A Olsso. The role of oxytocin receptor gene (OXTR) DNA methylation (DNAm) in human social and emotional functioning: a systematic narrative review. BMC psychiatry vol 18 issue 1 2019 29843655 |
this review brings together early findings in a rapidly developing field of research, examining relationships between dna methylation (dnam) of the oxytocin receptor gene (oxtr) and social and emotional behaviour in human populations. |
2019-03-01 |
2023-01-26 |
human |