All Relations between executive functions and microtubule-associated protein tau

Reference Sentence Publish Date Extraction Date Species
Shraddha Sapkota, Kelsey Erickson, Danielle Harvey, Sarah E Tomaszewski-Farias, John M Olichney, David K Johnson, Brittany N Dugger, Dan M Mungas, Evan Fletcher, Pauline Maillard, Sudha Seshadri, Claudia L Satizabal, Tiffany Kautz, Danielle Parent, Russell P Tracy, Izumi Maezawa, Lee-Way Jin, Charles DeCarl. Plasma biomarkers predict cognitive trajectories in an ethnoracially and clinically diverse cohort: Mediation with hippocampal volume. Alzheimer's & dementia (Amsterdam, Netherlands) vol 14 issue 1 2022 36092690 we examine whether the association between key plasma biomarkers (amyloid \xce\xb2 [a\xce\xb2] 42/40, total tau (t-tau), neurofilament light [nfl]) and cognitive trajectories (executive function [ef] and episodic memory [em]) is mediated through neurodegeneration. 2022-09-12 2022-09-14 Not clear
Cathryn McKenzie, Romola S Bucks, Michael Weinborn, Pierrick Bourgeat, Olivier Salvado, Brandon E Gavet. Tau and amyloid biomarkers modify the degree to which cognitive reserve and brain reserve predict cognitive decline. Journal of the International Neuropsychological Society : JINS vol issue 2022 36039968 we sought to determine whether the influence of these protective factors on executive function (ef) and daily function decline was dependent upon alzheimer's disease (ad) pathology severity, as measured by the total tau to beta-amyloid (t-\xcf\x84/a\xce\xb2 2022-08-30 2022-08-31 Not clear
Cathryn McKenzie, Romola S Bucks, Michael Weinborn, Pierrick Bourgeat, Olivier Salvado, Brandon E Gavet. Residual reserve index modifies the effect of amyloid pathology on fluorodeoxyglucose metabolism: Implications for efficiency and capacity in cognitive reserve. Frontiers in aging neuroscience vol 14 issue 2022 36034126 we sought to distinguish between brain and cognitive resilience by comparing interactions between the residual reserve index and amyloid, tau, and neurodegeneration ["at(n)"] biomarkers when predicting executive function. 2022-08-29 2022-08-31 Not clear
Paula Duarte-Guterman, Arianne Y Albert, Cindy K Barha, Liisa A M Galea, On Behalf Of The Alzheimer's Disease Neuroimaging Initiativ. Sex influences the effects of APOE genotype and Alzheimer's diagnosis on neuropathology and memory. Psychoneuroendocrinology vol 129 issue 2021 33962245 using the adni database (n\xc2\xa0=\xc2\xa0630 females, n\xc2\xa0=\xc2\xa0830 males), we analyzed the effect of sex, apoe genotype (non-carriers or carriers of apoe\xce\xb54 alleles), and diagnosis (cognitively normal (cn), early amci (emci), late amci (lmci), probable ad) on cognition (memory and executive function), hippocampal volume, and ad biomarkers (csf levels of amyloid beta, tau, and ptau). 2021-10-11 2022-01-13 Not clear
Shi-Dong Chen, Yu-Yuan Huang, Xue-Ning Shen, Yu Guo, Lan Tan, Qiang Dong, Jin-Tai Y. Longitudinal plasma phosphorylated tau 181 tracks disease progression in Alzheimer's disease. Translational psychiatry vol 11 issue 1 2021 34120152 a longitudinal increase of plasma p-tau181 was associated with abnormal cerebrospinal fluid biomarker levels (low a\xce\xb242, high phosphorylated tau, and high total tau, all p\xe2\x80\x89<\xe2\x80\x890.001), amyloid accumulation (p\xe2\x80\x89<\xe2\x80\x890.001) and hypometabolism (p\xe2\x80\x89=\xe2\x80\x890.002) on positron emission tomography, atrophy in structure imaging (small hippocampal (p\xe2\x80\x89=\xe2\x80\x890.030), middle temporal (p\xe2\x80\x89=\xe2\x80\x890.008), and whole brain (p\xe2\x80\x89=\xe2\x80\x890.027) volume, and large ventricular volume (p\xe2\x80\x89=\xe2\x80\x890.008)), and deteriorated cognitive performance (global cognition and memory, language, executive function, and visuospatial function, all p\xe2\x80\x89<\xe2\x80\x890.050) at baseline. 2021-07-14 2022-01-13 Not clear
Sheina Emrani, Hirra A Arain, Cassandra DeMarshall, Tal Nurie. APOE4 is associated with cognitive and pathological heterogeneity in patients with Alzheimer's disease: a systematic review. Alzheimer's research & therapy vol 12 issue 1 2021 33148345 on the other hand, apoe4- ad patients appear to possess more tau accumulation and brain atrophy in the frontal and parietal lobes, resulting in greater impairment in executive function, visuospatial abilities, and language, compared to apoe4+ ad patients. 2021-06-24 2022-01-13 Not clear
Yongxia Zhou, Bing Ba. Tau and Pet/Mri Imaging Biomarkers for Detecting and Diagnosing Early Dementia. Jacobs journal of medical diagnosis and medical imaging vol 2 issue 1 2020 29026896 significant correlations were found between tau deposition and memory as well as executive function scores, especially from middle and inferior temporal cortex; and significant correlations between tau and mri metrics including diffusion, perfusion, functional and structural connectivities. 2020-10-01 2022-01-13 Not clear
Isabelle Bos, Stephanie J B Vos, Willemijn J Jansen, Rik Vandenberghe, Silvy Gabel, Ainara Estanga, Mirian Ecay-Torres, Jori Tomassen, Anouk den Braber, Alberto Lle\\xc3\\xb3, Isabel Sala, Anders Wallin, Petronella Kettunen, Jos\\xc3\\xa9 L Molinuevo, Lorena Rami, Ga\\xc3\\xabl Chetelat, Vincent de la Sayette, Magda Tsolaki, Yvonne Freund-Levi, Peter Johannsen, Gerald P Novak, Inez Ramakers, Frans R Verhey, Pieter Jelle Visse. Amyloid-\\xce\\xb2, Tau, and Cognition in Cognitively Normal Older Individuals: Examining the Necessity to Adjust for Biomarker Status in Normative Data. Frontiers in aging neuroscience vol 10 issue 2020 29988624 linear mixed models were used to assess the associations of a\xce\xb2 and tau with five neuropsychological tests assessing memory (immediate and delayed recall of auditory verbal learning test, avlt), verbal fluency (verbal fluency test, vft), attention and executive functioning (trail making test, tmt, part a and b). 2020-10-01 2022-01-13 Not clear
Sarah Gourmaud, Haochang Shou, David J Irwin, Kimberly Sansalone, Leah M Jacobs, Timothy H Lucas, Eric D Marsh, Kathryn A Davis, Frances E Jensen, Delia M Talo. Alzheimer-like amyloid and tau alterations associated with cognitive deficit in temporal lobe epilepsy. Brain : a journal of neurology vol 143 issue 1 2020 31834353 in temporal lobe epilepsy cases, hippocampal levels of phosphorylated amyloid precursor protein, its pro-amyloidogenic processing enzyme beta-site amyloid precursor protein cleaving enzyme 1, and both total and hyperphosphorylated tau expression, correlated with impaired preoperative executive function. 2020-08-18 2022-01-13 Not clear
S Imindu Liyanage, Donald F Weave. Misfolded proteins as a therapeutic target in Alzheimer's disease. Advances in protein chemistry and structural biology vol 118 issue 2020 31928732 in particular, the extracellular peptide fragment: amyloid-\xce\xb2 (a\xce\xb2), and the intracellular microtubule-associated protein: tau, were thought to initiate a neurodegenerative cascade which culminated in ad's progressive loss of memory and executive function. 2020-04-02 2022-01-13 Not clear
Mary Ellen I Koran, Madison Wagener, Timothy J Hohma. Sex differences in the association between AD biomarkers and cognitive decline. Brain imaging and behavior vol 11 issue 1 2018 26843008 similarly, we observed an interaction between sex and total tau level on longitudinal hippocampal atrophy (p\xc2\xa0=\xc2\xa00.008), and longitudinal decline in executive function (p\xc2\xa0=\xc2\xa00.034). 2018-01-25 2022-01-12 Not clear
Brandon P Vasquez, Malcolm A Binns, Nicole D Anderso. Staying on Task: Age-Related Changes in the Relationship Between Executive Functioning and Response Time Consistency. The journals of gerontology. Series B, Psychological sciences and social sciences vol 71 issue 2 2016 25395345 little is known about the relationship of executive functioning with age-related increases in response time (rt) distribution indices (intraindividual standard deviation [isd], and ex-gaussian parameters mu, sigma, tau). 2016-06-16 2022-01-12 Not clear
Aamena Valiji Bharmal, Brianne A Kent, Timothy J Bussey, Lisa M Saksid. Performance of transgenic TgTau-P301L mice in a 5-choice serial reaction time task (5-CSRTT) as a model of Alzheimer's disease. Psychiatria Danubina vol 27 Suppl 1 issue 2015 26540742 the aim of the investigation is to observe if tau pathology in the tgtaup301l mice causes a cognitive impairment in attention and executive function and at what stage this can be identified by the 5-csrtt task. 2015-12-17 2022-01-12 Not clear
S Duke Han, Jonathan Gruhl, Laurel Beckett, Hiroko H Dodge, Nikki H Stricker, Sarah Farias, Dan Munga. Beta amyloid, tau, neuroimaging, and cognition: sequence modeling of biomarkers for Alzheimer's Disease. Brain imaging and behavior vol 6 issue 4 2013 22648764 we examined temporal relations among four classes of biomarkers: csf a\xce\xb2, csf tau, neuroimaging variables (hippocampal volume, ventricular volume, fdg pet), and cognitive variables (memory and executive function). 2013-08-02 2022-01-12 Not clear
Adriana Borriello, Andrea Balbi, Claudio Iannucci, Paola Recchioni, Patrizia Vincenzoni, Fiorino Mirabell. [A trial to measure the effectiveness of an intervention in the assessment and rehabilitation of cognitive functions in psychotic individuals]. Rivista di psichiatria vol 45 issue 5 2011 21268414 the present study aims to evaluate the outcome of two different approach in rehabilitation: ipt cognitive training (brenner's) administered in conjunction with treatment as usual (tau) versus tau as a sole intervention, on cognitive functions such as attention, memory, and executive functioning in a sample of participants with a diagnosis of a schizophrenia spectrum disorder. 2011-03-31 2022-01-12 Not clear