| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kyan Younes, Viktorija Smith, Emily Johns, Mackenzie L Carlson, Joseph Winer, Zihuai He, Victor W Henderson, Michael D Greicius, Christina B Young, Elizabeth C Mormin. Temporal tau asymmetry spectrum influences divergent behavior and language patterns in Alzheimer's disease. medRxiv : the preprint server for health sciences. 2023-11-21. PMID:37986964. |
this cross-sectional study investigated the correlation between temporal tau pet asymmetry and behavior assessed using the neuropsychiatric inventory, and composite scores for memory, executive function, and language; using data from the alzheimer's disease neuroimaging initiative (adni) dataset. |
2023-11-21 |
2023-11-29 |
human |
| Shanshan Wang, Suzhi Liu, Shaofa Ke, Wenjun Zhou, Tengwei Pa. APOEɛ4 Status and Plasma p-tau181 Levels May Influence Memory and Executive Function Decline in Older Adults Without Dementia. Journal of Alzheimer's disease : JAD. 2023-09-18. PMID:37718807. |
however, it is uncertain whether the impact of increased plasma tau phosphorylated at threonine 181 (p-tau181) on memory and executive function decline would be greater among apoeɛ4 carriers. |
2023-09-18 |
2023-10-07 |
Not clear |
| Shraddha Sapkota, Kelsey Erickson, Danielle Harvey, Sarah E Tomaszewski-Farias, John M Olichney, David K Johnson, Brittany N Dugger, Dan M Mungas, Evan Fletcher, Pauline Maillard, Sudha Seshadri, Claudia L Satizabal, Tiffany Kautz, Danielle Parent, Russell P Tracy, Izumi Maezawa, Lee-Way Jin, Charles DeCarl. Plasma biomarkers predict cognitive trajectories in an ethnoracially and clinically diverse cohort: Mediation with hippocampal volume. Alzheimer's & dementia (Amsterdam, Netherlands). vol 14. issue 1. 2022-09-12. PMID:36092690. |
we examine whether the association between key plasma biomarkers (amyloid β [aβ] 42/40, total tau (t-tau), neurofilament light [nfl]) and cognitive trajectories (executive function [ef] and episodic memory [em]) is mediated through neurodegeneration. |
2022-09-12 |
2023-08-14 |
Not clear |
| Cathryn McKenzie, Romola S Bucks, Michael Weinborn, Pierrick Bourgeat, Olivier Salvado, Brandon E Gavet. Tau and amyloid biomarkers modify the degree to which cognitive reserve and brain reserve predict cognitive decline. Journal of the International Neuropsychological Society : JINS. 2022-08-30. PMID:36039968. |
we sought to determine whether the influence of these protective factors on executive function (ef) and daily function decline was dependent upon alzheimer's disease (ad) pathology severity, as measured by the total tau to beta-amyloid (t-τ/aβ |
2022-08-30 |
2023-08-14 |
Not clear |
| Cathryn McKenzie, Romola S Bucks, Michael Weinborn, Pierrick Bourgeat, Olivier Salvado, Brandon E Gavet. Residual reserve index modifies the effect of amyloid pathology on fluorodeoxyglucose metabolism: Implications for efficiency and capacity in cognitive reserve. Frontiers in aging neuroscience. vol 14. 2022-08-29. PMID:36034126. |
we sought to distinguish between brain and cognitive resilience by comparing interactions between the residual reserve index and amyloid, tau, and neurodegeneration ["at(n)"] biomarkers when predicting executive function. |
2022-08-29 |
2023-08-14 |
Not clear |
| Paula Duarte-Guterman, Arianne Y Albert, Cindy K Barha, Liisa A M Galea, On Behalf Of The Alzheimer's Disease Neuroimaging Initiativ. Sex influences the effects of APOE genotype and Alzheimer's diagnosis on neuropathology and memory. Psychoneuroendocrinology. vol 129. 2021-10-11. PMID:33962245. |
using the adni database (n = 630 females, n = 830 males), we analyzed the effect of sex, apoe genotype (non-carriers or carriers of apoeε4 alleles), and diagnosis (cognitively normal (cn), early amci (emci), late amci (lmci), probable ad) on cognition (memory and executive function), hippocampal volume, and ad biomarkers (csf levels of amyloid beta, tau, and ptau). |
2021-10-11 |
2023-08-13 |
Not clear |
| Shi-Dong Chen, Yu-Yuan Huang, Xue-Ning Shen, Yu Guo, Lan Tan, Qiang Dong, Jin-Tai Y. Longitudinal plasma phosphorylated tau 181 tracks disease progression in Alzheimer's disease. Translational psychiatry. vol 11. issue 1. 2021-07-14. PMID:34120152. |
a longitudinal increase of plasma p-tau181 was associated with abnormal cerebrospinal fluid biomarker levels (low aβ42, high phosphorylated tau, and high total tau, all p < 0.001), amyloid accumulation (p < 0.001) and hypometabolism (p = 0.002) on positron emission tomography, atrophy in structure imaging (small hippocampal (p = 0.030), middle temporal (p = 0.008), and whole brain (p = 0.027) volume, and large ventricular volume (p = 0.008)), and deteriorated cognitive performance (global cognition and memory, language, executive function, and visuospatial function, all p < 0.050) at baseline. |
2021-07-14 |
2023-08-13 |
human |
| Sheina Emrani, Hirra A Arain, Cassandra DeMarshall, Tal Nurie. APOE4 is associated with cognitive and pathological heterogeneity in patients with Alzheimer's disease: a systematic review. Alzheimer's research & therapy. vol 12. issue 1. 2021-06-24. PMID:33148345. |
on the other hand, apoe4- ad patients appear to possess more tau accumulation and brain atrophy in the frontal and parietal lobes, resulting in greater impairment in executive function, visuospatial abilities, and language, compared to apoe4+ ad patients. |
2021-06-24 |
2023-08-13 |
Not clear |
| Yongxia Zhou, Bing Ba. Tau and Pet/Mri Imaging Biomarkers for Detecting and Diagnosing Early Dementia. Jacobs journal of medical diagnosis and medical imaging. vol 2. issue 1. 2020-10-01. PMID:29026896. |
significant correlations were found between tau deposition and memory as well as executive function scores, especially from middle and inferior temporal cortex; and significant correlations between tau and mri metrics including diffusion, perfusion, functional and structural connectivities. |
2020-10-01 |
2023-08-13 |
Not clear |
| Isabelle Bos, Stephanie J B Vos, Willemijn J Jansen, Rik Vandenberghe, Silvy Gabel, Ainara Estanga, Mirian Ecay-Torres, Jori Tomassen, Anouk den Braber, Alberto Lleó, Isabel Sala, Anders Wallin, Petronella Kettunen, José L Molinuevo, Lorena Rami, Gaël Chetelat, Vincent de la Sayette, Magda Tsolaki, Yvonne Freund-Levi, Peter Johannsen, Gerald P Novak, Inez Ramakers, Frans R Verhey, Pieter Jelle Visse. Amyloid-β, Tau, and Cognition in Cognitively Normal Older Individuals: Examining the Necessity to Adjust for Biomarker Status in Normative Data. Frontiers in aging neuroscience. vol 10. 2020-10-01. PMID:29988624. |
linear mixed models were used to assess the associations of aβ and tau with five neuropsychological tests assessing memory (immediate and delayed recall of auditory verbal learning test, avlt), verbal fluency (verbal fluency test, vft), attention and executive functioning (trail making test, tmt, part a and b). |
2020-10-01 |
2023-08-13 |
Not clear |
| Sarah Gourmaud, Haochang Shou, David J Irwin, Kimberly Sansalone, Leah M Jacobs, Timothy H Lucas, Eric D Marsh, Kathryn A Davis, Frances E Jensen, Delia M Talo. Alzheimer-like amyloid and tau alterations associated with cognitive deficit in temporal lobe epilepsy. Brain : a journal of neurology. vol 143. issue 1. 2020-08-18. PMID:31834353. |
in temporal lobe epilepsy cases, hippocampal levels of phosphorylated amyloid precursor protein, its pro-amyloidogenic processing enzyme beta-site amyloid precursor protein cleaving enzyme 1, and both total and hyperphosphorylated tau expression, correlated with impaired preoperative executive function. |
2020-08-18 |
2023-08-13 |
Not clear |
| S Imindu Liyanage, Donald F Weave. Misfolded proteins as a therapeutic target in Alzheimer's disease. Advances in protein chemistry and structural biology. vol 118. 2020-04-02. PMID:31928732. |
in particular, the extracellular peptide fragment: amyloid-β (aβ), and the intracellular microtubule-associated protein: tau, were thought to initiate a neurodegenerative cascade which culminated in ad's progressive loss of memory and executive function. |
2020-04-02 |
2023-08-13 |
Not clear |
| Mary Ellen I Koran, Madison Wagener, Timothy J Hohma. Sex differences in the association between AD biomarkers and cognitive decline. Brain imaging and behavior. vol 11. issue 1. 2018-01-25. PMID:26843008. |
similarly, we observed an interaction between sex and total tau level on longitudinal hippocampal atrophy (p = 0.008), and longitudinal decline in executive function (p = 0.034). |
2018-01-25 |
2023-08-13 |
human |
| Brandon P Vasquez, Malcolm A Binns, Nicole D Anderso. Staying on Task: Age-Related Changes in the Relationship Between Executive Functioning and Response Time Consistency. The journals of gerontology. Series B, Psychological sciences and social sciences. vol 71. issue 2. 2016-06-16. PMID:25395345. |
little is known about the relationship of executive functioning with age-related increases in response time (rt) distribution indices (intraindividual standard deviation [isd], and ex-gaussian parameters mu, sigma, tau). |
2016-06-16 |
2023-08-13 |
Not clear |
| Aamena Valiji Bharmal, Brianne A Kent, Timothy J Bussey, Lisa M Saksid. Performance of transgenic TgTau-P301L mice in a 5-choice serial reaction time task (5-CSRTT) as a model of Alzheimer's disease. Psychiatria Danubina. vol 27 Suppl 1. 2015-12-17. PMID:26540742. |
the aim of the investigation is to observe if tau pathology in the tgtaup301l mice causes a cognitive impairment in attention and executive function and at what stage this can be identified by the 5-csrtt task. |
2015-12-17 |
2023-08-13 |
mouse |
| S Duke Han, Jonathan Gruhl, Laurel Beckett, Hiroko H Dodge, Nikki H Stricker, Sarah Farias, Dan Munga. Beta amyloid, tau, neuroimaging, and cognition: sequence modeling of biomarkers for Alzheimer's Disease. Brain imaging and behavior. vol 6. issue 4. 2013-08-02. PMID:22648764. |
we examined temporal relations among four classes of biomarkers: csf aβ, csf tau, neuroimaging variables (hippocampal volume, ventricular volume, fdg pet), and cognitive variables (memory and executive function). |
2013-08-02 |
2023-08-12 |
Not clear |
| Adriana Borriello, Andrea Balbi, Claudio Iannucci, Paola Recchioni, Patrizia Vincenzoni, Fiorino Mirabell. [A trial to measure the effectiveness of an intervention in the assessment and rehabilitation of cognitive functions in psychotic individuals]. Rivista di psichiatria. vol 45. issue 5. 2011-03-31. PMID:21268414. |
the present study aims to evaluate the outcome of two different approach in rehabilitation: ipt cognitive training (brenner's) administered in conjunction with treatment as usual (tau) versus tau as a sole intervention, on cognitive functions such as attention, memory, and executive functioning in a sample of participants with a diagnosis of a schizophrenia spectrum disorder. |
2011-03-31 |
2023-08-12 |
human |