| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hong-Jin Shu, Luke H Ziolkowski, Sofia V Salvatore, Ann M Benz, David F Wozniak, Carla M Yuede, Steven M Paul, Charles F Zorumski, Steven Menneric. Effects of Complete and Partial Loss of the 24S-Hydroxycholesterol-Generating Enzyme Biomolecules. vol 14. issue 3. 2024-03-28. PMID:38540675. |
mice that are globally deficient in cyp46a1 exhibited hypoactivity at young ages and unexpected increases in conditioned fear memory. |
2024-03-28 |
2024-03-30 |
mouse |
| Hiroko Ikeda, Aimi Yamagishi, Naomi Yonemochi, Shogo Yamamoto, Takatsune Shimizu, Akihiro Muto, John L Waddington, Junzo Kame. Keratinocyte-Derived Cytokine in the Hippocampus Disrupts Extinction of Conditioned Fear Memory in Tumor-Bearing Mice. Molecular neurobiology. 2024-02-03. PMID:38308664. |
keratinocyte-derived cytokine in the hippocampus disrupts extinction of conditioned fear memory in tumor-bearing mice. |
2024-02-03 |
2024-02-06 |
mouse |
| Hiroko Ikeda, Aimi Yamagishi, Naomi Yonemochi, Shogo Yamamoto, Takatsune Shimizu, Akihiro Muto, John L Waddington, Junzo Kame. Keratinocyte-Derived Cytokine in the Hippocampus Disrupts Extinction of Conditioned Fear Memory in Tumor-Bearing Mice. Molecular neurobiology. 2024-02-03. PMID:38308664. |
the microglia inhibitor minocycline, but not the astrocyte inhibitor fluorocitrate, alleviated disruption in extinction of conditioned fear memory in tb mice. |
2024-02-03 |
2024-02-06 |
mouse |
| Stephanie Boehme, Martin J Herrmann, Andreas Mühlberge. Good Moments to Stimulate the Brain - A randomized controlled double-blinded study on anodal transcranial direct current stimulation of the ventromedial prefrontal cortex on two different time points in a two-day fear conditioning paradigm. Behavioural brain research. 2023-12-16. PMID:38103872. |
therefore, we investigated in a 2-day fear conditioning experiment, whether anodal transcranial direct current stimulation (tdcs) of the ventromedial prefrontal cortex (vmpfc) modulates either fear memory consolidation or dampened fear reaction during fear extinction. |
2023-12-16 |
2023-12-21 |
human |
| Miki Hashizume, Rina Ito, Rie Suge, Yasushi Hojo, Gen Murakami, Takayuki Murakosh. Correlation between cue fear memory retrieval and oscillatory network inhibition in the amygdala is disrupted by acute REM sleep deprivation. Neuroscience. 2023-11-09. PMID:37944580. |
in particular, fear memory after cued fear conditioning is strongly associated with the bla, whereas both the bla and hippocampus are essential for contextual fear memory formation. |
2023-11-09 |
2023-11-20 |
rat |
| Miki Hashizume, Rina Ito, Rie Suge, Yasushi Hojo, Gen Murakami, Takayuki Murakosh. Correlation between cue fear memory retrieval and oscillatory network inhibition in the amygdala is disrupted by acute REM sleep deprivation. Neuroscience. 2023-11-09. PMID:37944580. |
in the present study, sd either before or after fear conditioning (fc) disturbed the acquisition of tone-associated fear memory without significant effects on contextual fear memory. |
2023-11-09 |
2023-11-20 |
rat |
| Casagrande, R R Porto, J Haubrich, A Kautzmann, L de Oliveira Álvare. EMOTIONAL VALUE OF FEAR MEMORY AND THE ROLE OF THE VENTRAL HIPPOCAMPUS IN SYSTEMS CONSOLIDATION. Neuroscience. 2023-11-09. PMID:37944583. |
here, we investigatedhow distinct training intensities, with strong or weakcontextual fear conditioning, affect activation of the dorsal hippocampus (dhpc) and the vhpc.we foundthatthe time course of memory consolidation differs in fear memories of different training intensities in both the dhpc and vhpc.our results also indicate that memory generalization happens alongside greater activation of the vhpc, and these processes occur faster with stronger fear memories.the vhpc is required for the expression of remote fear memory andmay controlcontextual fear generalization,a view corroborated by the fact that inactivation of the vhpc suppresses generalized fear expression, making memory more precise again. |
2023-11-09 |
2023-11-20 |
Not clear |
| Jennyfer M Payet, Laura Stevens, Adrian M Russo, Emily Jaehne, Maarten van den Buuse, Stephen Kent, Christopher A Lowry, Michael V Baratta, Matthew W Hal. The Role of Dorsal Raphe Nucleus Serotonergic Systems in Emotional Learning and Memory in Male BALB/c Mice. Neuroscience. 2023-10-23. PMID:37852412. |
activation of dr serotonergic neurons during fear conditioning (experiment 1) or fear memory recall (experiment 2), was measured using dual-label immunohistochemistry for tph2 and c-fos. |
2023-10-23 |
2023-11-08 |
mouse |
| Rebecca Ravenelle, Carolina Fernandes-Henriques, Jinah Lee, Jia Liu, Ekaterina Likhtik, Nesha S Burghard. Serotonergic Modulation of the BNST-CeA Circuit Promotes Sex Differences in Fear Learning. bioRxiv : the preprint server for biology. 2023-07-18. PMID:37461483. |
females showed higher sensitivity to the effects of pharmacologically increasing serotonin during auditory fear conditioning, which enhanced fear memory recall in both sexes. |
2023-07-18 |
2023-08-14 |
mouse |
| Rebecca Ravenelle, Carolina Fernandes-Henriques, Jinah Lee, Jia Liu, Ekaterina Likhtik, Nesha S Burghard. Serotonergic Modulation of the BNST-CeA Circuit Promotes Sex Differences in Fear Learning. bioRxiv : the preprint server for biology. 2023-07-18. PMID:37461483. |
optogenetic stimulation of dorsal raphe terminals in the anterior dorsal bed nucleus of the stria terminalis (adbnst) during fear conditioning increased c-fos expression in the bnst and central nucleus of the amygdala (cea), and enhanced fear memory recall via activation of adbnst 5-ht2c receptors in females only. |
2023-07-18 |
2023-08-14 |
mouse |
| Youjia Yu, Yan Li, Dan Han, Chuhao Gong, Liwei Wang, Beiping Li, Rui Yao, Yangzi Zh. Effect of Dexmedetomidine on Posttraumatic Stress Disorder in Patients Undergoing Emergency Trauma Surgery: A Randomized Clinical Trial. JAMA network open. vol 6. issue 6. 2023-06-16. PMID:37326991. |
dexmedetomidine may reduce or reverse the early consolidation and formation of conditioned fear memory and prevent the occurrence of postoperative ptsd. |
2023-06-16 |
2023-08-14 |
Not clear |
| Austin M Adkins, Emily M Colby, Woong-Ki Kim, Laurie L Wellman, Larry D Sanfor. Stressor control and regional inflammatory responses in the brain: regulation by the basolateral amygdala. Journal of neuroinflammation. vol 20. issue 1. 2023-05-27. PMID:37244986. |
we have also demonstrated that the basolateral amygdala (bla) regulates stress- and fear memory-induced alterations in sleep, and that differential sleep and immune responses in the brain to es and is appear to be integrated during fear conditioning and then reproduced by fear memory recall. |
2023-05-27 |
2023-08-14 |
mouse |
| Tianyu Wang, Rongzhen Yan, Xinyang Zhang, Zongliang Wang, Haoyu Duan, Zeyi Wang, Qiang Zho. Paraventricular thalamus dynamically modulates aversive memory via tuning prefrontal inhibitory circuitry. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-04-17. PMID:37068932. |
here, we used male c57bl6/j mice in an auditory fear conditioning as a model system to examine this question and focused on the impact of stress on dorsomedial prefrontal cortex (dmpfc) neurons which play an important role in probabilistic fear memory. |
2023-04-17 |
2023-08-14 |
mouse |
| Cemal Akmese, Cem Sevinc, Sahar Halim, Gunes Una. Differential role of GABAergic and cholinergic ventral pallidal neurons in behavioral despair, conditioned fear memory and active coping. Progress in neuro-psychopharmacology & biological psychiatry. 2023-04-09. PMID:37031946. |
differential role of gabaergic and cholinergic ventral pallidal neurons in behavioral despair, conditioned fear memory and active coping. |
2023-04-09 |
2023-08-14 |
rat |
| Francisca Silva, Gianluca Masella, Maria Francisca Madeira, Carlos B Duarte, Mónica Santo. TrkC Intracellular Signalling in the Brain Fear Network During the Formation of a Contextual Fear Memory. Molecular neurobiology. 2023-03-07. PMID:36882590. |
here, we put wild-type c57bl/6j mice through a contextual fear conditioning paradigm in order to characterize trkc activation and expression in the main brain regions involved in (learned) fear - amygdala, hippocampus, and prefrontal cortex - during the formation of a fear memory. |
2023-03-07 |
2023-08-14 |
mouse |
| Meilun Shen, Mengjuan Shang, Ruofei Tian, Yang Hu, Qian Han, Junfeng Hu, Guangzhou An, Bingxia Wang, Zhi Cao, Xiaoyu Lin, Hao Yang, Junling Xin. Single Cell Molecular Alterations Reveal Target Cells and Pathways of Conditioned Fear Memory. Brain research. 2023-03-04. PMID:36870465. |
recent evidence indicates that hippocampus is important for conditioned fear memory (cfm). |
2023-03-04 |
2023-08-14 |
Not clear |
| Joana Freitas Costa, Monica Dines, Karishma Agarwal, Raphael Lamprech. Rac1 GTPase activation impairs fear conditioning-induced structural changes in basolateral amygdala neurons and long-term fear memory formation. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2022-12-15. PMID:36522403. |
these results show that fear conditioning induces changes known to reduce the inhibition of signal propagation along the dendrite and the increase in synaptic efficacy whereas preventing these changes, by rac1 activation, impairs fear memory formation. |
2022-12-15 |
2023-08-14 |
Not clear |
| Or Ilovich, Monica Dines, Blesson K Paul, Edi Barkai, Raphael Lamprech. Nck1 activity in lateral amygdala regulates long-term fear memory formation. Translational psychiatry. vol 12. issue 1. 2022-11-12. PMID:36371406. |
fear conditioning leads to long-term fear memory formation and is a model for studying fear-related psychopathological conditions such as phobias and post-traumatic stress disorder. |
2022-11-12 |
2023-08-14 |
Not clear |
| Or Ilovich, Monica Dines, Blesson K Paul, Edi Barkai, Raphael Lamprech. Nck1 activity in lateral amygdala regulates long-term fear memory formation. Translational psychiatry. vol 12. issue 1. 2022-11-12. PMID:36371406. |
activation of nck1, by using a photoactivatable nck1 (pa-nck1), during auditory fear conditioning in excitatory neurons in la impaired long-term, but not short-term, fear memory. |
2022-11-12 |
2023-08-14 |
Not clear |
| Or Ilovich, Monica Dines, Blesson K Paul, Edi Barkai, Raphael Lamprech. Nck1 activity in lateral amygdala regulates long-term fear memory formation. Translational psychiatry. vol 12. issue 1. 2022-11-12. PMID:36371406. |
activation of nck1 immediately or a day after fear conditioning did not affect fear memory. |
2022-11-12 |
2023-08-14 |
Not clear |