All Relations between feeding and 5-ht receptor 6

Reference Sentence Publish Date Extraction Date Species
Grace E Anderson, Alexandra Sharp, Wayne E Prat. Stimulation of nucleus accumbens 5-HT6 receptors increases both appetitive and consummatory motivation in an effort-based choice task. Neuroreport vol 34 issue 2 2023 36608167 activity of the serotonin 6(5-ht6) receptor impacts food intake and body weight in animal models and has also shown potential as a target for treatment of anhedonia, a symptom of major depressive disorder. 2023-01-06 2023-01-08 Not clear
Amanda Alves Marcelino da Silva, Mayara Matias Oliveira, Taisy Cinthia Ferro Cavalcante, Larissa Cavalcanti do Amaral Almeida, Paula Luiza Menezes Cruz, Sandra Lopes de Souz. Undernutrition during pregnancy and lactation increases the number of fos-cells in the reward system in response to a 5-HT6 receptor agonist in male adolescent rats. International journal of food sciences and nutrition vol 69 issue 4 2018 28958176 therefore, we aimed to evaluate the effect of a 5-ht6 receptor agonist on food intake and neuronal activation in areas of the reward system in adolescent rats subjected to perinatal protein undernutrition. 2018-09-12 2022-01-13 Not clear
D J Heal, S L Smith, A Fisas, X Codony, H Buschman. Selective 5-HT6 receptor ligands: progress in the development of a novel pharmacological approach to the treatment of obesity and related metabolic disorders. Pharmacology & therapeutics vol 117 issue 2 2008 18068807 in animal models, 5-ht6 receptor ligands of all functional types have been shown to decrease food intake when given acutely and chronically, to evoke profound and sustained weight-loss in obese animals, and concomitantly to improve a number of cardio-metabolic risk factors. 2008-03-27 2022-01-13 Not clear
Remigiusz Zieb. [Obesity: a review of currently used antiobesity drugs and new compounds in clinical development]. Postepy higieny i medycyny doswiadczalnej (Online) vol 61 issue 2008 17971763 the new antiobesity drugs under clinical development include: 1) agents that affect neurotransmitters in the central nervous system, including noradrenaline and dopamine reuptake inhibitors (bupropion, radafaxine), selective 5ht2c receptor agonists (lorcaserin), and selective 5ht6 receptor antagonists, 2) agents that modulate the activity of neuropeptides influencing food intake, including leptin analogues, human ciliary neurotrophic factor (axokine), neuropeptide y antagonists, and melanine-concentrating hormone antagonists, 3) agents that affect the peripheral satiety signals and brain-gut axis, e.g. 2008-02-04 2022-01-12 Not clear
Jason C G Halford, Joanne A Harrold, Emma J Boyland, Clare L Lawton, John E Blundel. Serotonergic drugs : effects on appetite expression and use for the treatment of obesity. Drugs vol 67 issue 1 2007 17209663 in addition, 5-ht6 receptor antagonists such as prx-07034 and bvt74316 have been shown to potently reduce food intake and bodyweight gain in rodent models and have recently entered clinical trials. 2007-03-21 2022-01-12 Not clear
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