| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Swen Hesse, Elsmarieke van de Giessen, Franziska Zientek, David Petroff, Karsten Winter, John C Dickson, Livia Tossici-Bolt, Terez Sera, Susanne Asenbaum, Jacques Darcourt, Umit O Akdemir, Gitte M Knudsen, Flavio Nobili, Marco Pagani, Thierry Vander Borght, Koen Van Laere, Andrea Varrone, Klaus Tatsch, Osama Sabri, Jan Booi. Association of central serotonin transporter availability and body mass index in healthy Europeans. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 24. issue 8. 2015-03-30. PMID:24976619. |
serotonin-mediated mechanisms, in particular via the serotonin transporter (sert), are thought to have an effect on food intake and play an important role in the pathophysiology of obesity. |
2015-03-30 |
2023-08-13 |
human |
| Oleg Otlivanchik, Christelle Le Foll, Barry E Levi. Perifornical hypothalamic orexin and serotonin modulate the counterregulatory response to hypoglycemic and glucoprivic stimuli. Diabetes. vol 64. issue 1. 2015-03-11. PMID:25114294. |
depleting pfh 5-ht blunted the epi (but not feeding) response to focal pfh (69%) and systemic glucoprivation (39%), while increasing pfh 5-ht levels amplified the epi response to hypoglycemia by 32%. |
2015-03-11 |
2023-08-13 |
rat |
| Oleg Otlivanchik, Christelle Le Foll, Barry E Levi. Perifornical hypothalamic orexin and serotonin modulate the counterregulatory response to hypoglycemic and glucoprivic stimuli. Diabetes. vol 64. issue 1. 2015-03-11. PMID:25114294. |
thus we have identified the pfh as a glucoregulatory region where both 5-ht and orexin modulate the crr and feeding responses to glucoprivation. |
2015-03-11 |
2023-08-13 |
rat |
| Yvette Taché, David Adelson, Hong Yan. TRH/TRH-R1 receptor signaling in the brain medulla as a pathway of vagally mediated gut responses during the cephalic phase. Current pharmaceutical design. vol 20. issue 16. 2015-01-26. PMID:23886382. |
the gastric response to trh injected into the dmn is potentiated by serotonin and the protrh flanking peptide, ps4 and suppressed by a number of brainstem peptides and cytokines activated during stress or immune response and inhibiting food intake and gastric acid secretion. |
2015-01-26 |
2023-08-12 |
rat |
| Luke K Burke, Barbora Doslikova, Giuseppe D'Agostino, Alastair S Garfield, Gala Farooq, Denis Burdakov, Malcolm J Low, Marcelo Rubinstein, Mark L Evans, Brian Billups, Lora K Heisle. 5-HT obesity medication efficacy via POMC activation is maintained during aging. Endocrinology. vol 155. issue 10. 2015-01-05. PMID:25051442. |
we next investigated whether age-related diminished arc pomc activity therefore impacts the potency of 5-ht obesity pharmacotherapies, lorcaserin, d-fenfluramine, and sibutramine and report that all compounds reduced food intake to a comparable extent in both chow-fed young lean (3-5 months old) and middle-aged obese (12-14 months old) male and female mice. |
2015-01-05 |
2023-08-13 |
mouse |
| Martha León-Olea, Christopher J Martyniuk, Edward F Orlando, Mary Ann Ottinger, Cheryl Rosenfeld, Jennifer Wolstenholme, Vance L Trudea. Current concepts in neuroendocrine disruption. General and comparative endocrinology. vol 203. 2014-12-16. PMID:24530523. |
fluoxetine is a selective serotonin reuptake inhibitor that can affect multiple neuroendocrine pathways and behavioral circuits, including disruptive effects on reproduction and feeding in fish. |
2014-12-16 |
2023-08-12 |
Not clear |
| Jorge J Pérez Maceira, María J Mancebo, Manuel Aldegund. The involvement of 5-HT-like receptors in the regulation of food intake in rainbow trout (Oncorhynchus mykiss). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. vol 161. 2014-10-29. PMID:24365333. |
it is known that in fish the serotonergic system is part of the neural network that controls feeding and that a pharmacologically induced increase in the brain 5-ht inhibits food intake. |
2014-10-29 |
2023-08-12 |
Not clear |
| Alice S French, Kerry L Simcock, Daniel Rolke, Sarah E Gartside, Wolfgang Blenau, Geraldine A Wrigh. The role of serotonin in feeding and gut contractions in the honeybee. Journal of insect physiology. vol 61. 2014-09-30. PMID:24374107. |
although feeding with sucrose caused a small elevation of endogenous 5-ht levels in the haemolymph, injection of exogenous 5-ht directly into the abdomen of the bee to elevate 5-ht in the haemolymph did not alter food intake. |
2014-09-30 |
2023-08-12 |
bee |
| Alice S French, Kerry L Simcock, Daniel Rolke, Sarah E Gartside, Wolfgang Blenau, Geraldine A Wrigh. The role of serotonin in feeding and gut contractions in the honeybee. Journal of insect physiology. vol 61. 2014-09-30. PMID:24374107. |
our data demonstrate that 5-ht inhibits feeding in the brain and excites muscle contractions in the gut, but general elevation of 5-ht in the bee's haemolymph does not affect food intake. |
2014-09-30 |
2023-08-12 |
bee |
| C Yang, R E Brow. The cholinergic agonist carbachol increases the frequency of spontaneous GABAergic synaptic currents in dorsal raphe serotonergic neurons in the mouse. Neuroscience. vol 258. 2014-09-29. PMID:24231737. |
dorsal raphe nucleus (drn) serotonin (5-ht) neurons play an important role in feeding, mood control and stress responses. |
2014-09-29 |
2023-08-12 |
mouse |
| Antonella Gasbarri, Assunta Pompil. Serotonergic 5-HT7 receptors and cognition. Reviews in the neurosciences. vol 25. issue 3. 2014-09-25. PMID:24486730. |
the abundant distribution of serotonin (5-ht) in different areas of the central nervous system can explain the involvement of this neurotransmitter in the regulation of several functions, such as sleep, pain, feeding, and sexual and emotional behaviors. |
2014-09-25 |
2023-08-12 |
Not clear |
| Yumi Harada, Kiyoshige Takayama, Shoki Ro, Mitsuko Ochiai, Masamichi Noguchi, Seiichi Iizuka, Tomohisa Hattori, Koji Yakab. Urocortin1-induced anorexia is regulated by activation of the serotonin 2C receptor in the brain. Peptides. vol 51. 2014-09-02. PMID:24269295. |
this study was conducted to determine the mechanisms by which serotonin (5-hydroxytryptamine, 5-ht) receptors are involved in the suppression of food intake in a rat stress model and to observe the degree of activation in the areas of the brain involved in feeding. |
2014-09-02 |
2023-08-12 |
rat |
| Luigi Brunetti, Giustino Orlando, Claudio Ferrante, Lucia Recinella, Sheila Leone, Annalisa Chiavaroli, Chiara Di Nisio, Rugia Shohreh, Fabio Manippa, Adriana Ricciuti, Michele Vacc. Peripheral chemerin administration modulates hypothalamic control of feeding. Peptides. vol 51. 2014-09-02. PMID:24269538. |
chemerin administration (8 and 16μg/kg) decreased both food intake and body weight compared to vehicle, possibly associated with a significant increase in serotonin synthesis and release, in the hypothalamus. |
2014-09-02 |
2023-08-12 |
rat |
| M Conde-Sieira, J L P Muñoz, M A López-Patiño, M Gesto, J L Soengas, J M Mígue. Oral administration of melatonin counteracts several of the effects of chronic stress in rainbow trout. Domestic animal endocrinology. vol 46. 2014-08-27. PMID:24411181. |
to assess a possible antistress role of melatonin in fish, we orally administered melatonin to rainbow trout for 10 d and then kept the fish under normal or high stocking density conditions during the last 4 d. food intake; biochemical parameters in plasma (cortisol, glucose, and lactate concentrations); liver (glucose and glycogen concentrations, and glycogen synthase activity); enzyme activities of amylase, lipase, and protease in foregut and midgut; and content of the hypothalamic neurotransmitters dopamine and serotonin, as well as their oxidized metabolites, 3,4-dihydroxyphenylacetic acid and 5-hydroxy-3-indoleacetic acid, were evaluated under those conditions. |
2014-08-27 |
2023-08-12 |
Not clear |
| Leticia Manuel-Apolinar, Luisa Rocha, Leticia Damasio, Emiliano Tesoro-Cruz, Arturo Zarat. Role of prenatal undernutrition in the expression of serotonin, dopamine and leptin receptors in adult mice: implications of food intake. Molecular medicine reports. vol 9. issue 2. 2014-08-26. PMID:24337628. |
role of prenatal undernutrition in the expression of serotonin, dopamine and leptin receptors in adult mice: implications of food intake. |
2014-08-26 |
2023-08-12 |
mouse |
| I M Szeto, M E Payne, A Jahan-Mihan, J Duan, G H Anderso. Multivitamin supplementation during pregnancy alters body weight and macronutrient selection in Wistar rat offspring. Journal of developmental origins of health and disease. vol 1. issue 6. 2014-08-22. PMID:25142010. |
the hypothesis that vitamin content of the diet during gestation alters macronutrient choice, food intake and the expression of serotonin receptors and proopiomelanocortin (pomc) in the hypothalamus of the offspring was investigated. |
2014-08-22 |
2023-08-13 |
rat |
| I M Szeto, M E Payne, A Jahan-Mihan, J Duan, G H Anderso. Multivitamin supplementation during pregnancy alters body weight and macronutrient selection in Wistar rat offspring. Journal of developmental origins of health and disease. vol 1. issue 6. 2014-08-22. PMID:25142010. |
in conclusion, intake of multivitamins above the requirements during pregnancy affected macronutrient choice, food intake and the expression of serotonin receptors and pomc in the hypothalamus. |
2014-08-22 |
2023-08-13 |
rat |
| Katherine M Serafine, Charles P Franc. Restricted access to standard or high fat chow alters sensitivity of rats to the 5-HT(2A/2C) receptor agonist 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane. Behavioural pharmacology. vol 25. issue 1. 2014-08-11. PMID:24346289. |
feeding conditions can impact sensitivity to drugs acting on dopamine receptors; less is known about the impact of feeding conditions on the effects of drugs acting on serotonin (5-ht) receptors. |
2014-08-11 |
2023-08-12 |
rat |
| Katherine M Serafine, Charles P Franc. Restricted access to standard or high fat chow alters sensitivity of rats to the 5-HT(2A/2C) receptor agonist 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane. Behavioural pharmacology. vol 25. issue 1. 2014-08-11. PMID:24346289. |
this study examined the effects of feeding conditions on sensitivity to the direct-acting 5-ht(2a/2c) receptor agonist 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane (dom; 0.1-3.2 mg/kg) and the direct-acting dopamine d3/d2 receptor agonist quinpirole (0.0032-0.32 mg/kg). |
2014-08-11 |
2023-08-12 |
rat |
| Katherine M Serafine, Charles P Franc. Restricted access to standard or high fat chow alters sensitivity of rats to the 5-HT(2A/2C) receptor agonist 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane. Behavioural pharmacology. vol 25. issue 1. 2014-08-11. PMID:24346289. |
some drugs of abuse and many therapeutic drugs act on 5-ht and dopamine systems; these results show that feeding conditions impact sensitivity to drugs acting on these systems, thereby possibly affecting vulnerability to abuse, as well as the therapeutic effectiveness of drugs. |
2014-08-11 |
2023-08-12 |
rat |