| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pol Bech, Sylvain Crochet, Robin Dard, Parviz Ghaderi, Yanqi Liu, Meriam Malekzadeh, Carl C H Petersen, Mauro Pulin, Anthony Renard, Christos Sourmpi. Striatal Dopamine Signals and Reward Learning. Function (Oxford, England). vol 4. issue 6. 2023-10-16. PMID:37841525. |
neuronal circuits of the basal ganglia have been strongly implicated in action selection, as well as the learning and execution of goal-directed behaviors, with accumulating evidence supporting the hypothesis that midbrain dopamine neurons might encode a reward signal useful for learning. |
2023-10-16 |
2023-11-08 |
Not clear |
| Paula A Zamudio, Dominic Gioia, Christina Glaser, John J Woodwar. Chemogenetic perturbation of the posterior but not anterior cerebellum reduces voluntary ethanol consumption. eNeuro. 2023-09-07. PMID:37679043. |
the cerebellum communicates with brain areas critically involved in control of goal-directed behaviors including the prefrontal and orbitofrontal cortices and midbrain and basal ganglia structures. |
2023-09-07 |
2023-10-07 |
mouse |
| Virginie J Oberto, Jumpei Matsumoto, Marco N Pompili, Ralitsa Todorova, Francesco Papaleo, Hisao Nishijo, Laurent Venance, Marie Vandecasteele, Sidney I Wiene. Rhythmic oscillations in the midbrain dopaminergic nuclei in mice. Frontiers in cellular neuroscience. vol 17. 2023-07-10. PMID:37426551. |
dopamine release in the forebrain by midbrain ventral tegmental nucleus (vta) and substantia nigra pars compacta (snc) neurons is implicated in reward processing, goal-directed learning, and decision-making. |
2023-07-10 |
2023-08-14 |
mouse |
| Kyna-Anne Conn, Simin Zou, Joyosmita Das, Suzy Alexander, Thomas Hj Burne, James P Kesb. Activating the dorsomedial and ventral midbrain projections to the striatum differentially impairs goal-directed action in male mice. Neuropharmacology. 2023-04-21. PMID:37085011. |
activating the dorsomedial and ventral midbrain projections to the striatum differentially impairs goal-directed action in male mice. |
2023-04-21 |
2023-08-14 |
mouse |
| Susanna Molas, Rubing Zhao-Shea, Timothy G Freels, Andrew R Tappe. Viral tracing confirms paranigral ventral tegmental area dopaminergic inputs to the interpeduncular nucleus where dopamine release encodes motivated exploration. eNeuro. 2023-01-04. PMID:36599671. |
midbrain dopaminergic (daergic) neurons of the ventral tegmental area (vta) are engaged by rewarding stimuli and encode reward prediction error to update goal-directed learning. |
2023-01-04 |
2023-08-14 |
mouse |
| Karolina Farrell, Armin Lak, Aman B Salee. Midbrain dopamine neurons signal phasic and ramping reward prediction error during goal-directed navigation. Cell reports. vol 41. issue 2. 2022-10-12. PMID:36223748. |
our results suggest that midbrain dopamine neurons encode phasic and ramping reward prediction error signals to improve goal-directed navigation. |
2022-10-12 |
2023-08-14 |
mouse |
| Karolina Farrell, Armin Lak, Aman B Salee. Midbrain dopamine neurons signal phasic and ramping reward prediction error during goal-directed navigation. Cell reports. vol 41. issue 2. 2022-10-12. PMID:36223748. |
midbrain dopamine neurons signal phasic and ramping reward prediction error during goal-directed navigation. |
2022-10-12 |
2023-08-14 |
mouse |
| Mengjiao Chen, Fangqing Liu, Longying Wen, Xia H. Nonlinear relationship between CAN current and Cognitive neurodynamics. vol 16. issue 3. 2022-05-23. PMID:35603052. |
nonlinear relationship between can current and bursting of midbrain dopamine (da) neurons is believed to represent an important reward signal that instructs and reinforces goal-directed behaviors. |
2022-05-23 |
2023-08-13 |
Not clear |
| Mikhail U Inyushin, Francisco Arencibia-Albite, Angel de la Cruz, Rafael Vázquez-Torres, Katiria Colon, Priscila Sanabria, Carlos A Jiménez-River. New method to visualize neurons with DAT in slices of rat VTA using fluorescent substrate for DAT, ASP+ Journal of neuroscience and neuroengineering. vol 2. issue 2. 2021-10-21. PMID:24052926. |
new method to visualize neurons with dat in slices of rat vta using fluorescent substrate for dat, asp+ the ventral tegmental area (vta), and in particular dopamine (da) neurons in this region of midbrain, has been shown to play an important role in motivation (goal-directed behavior), reward, and drug addiction. |
2021-10-21 |
2023-08-12 |
rat |
| Aurélie De Groote, Alban de Kerchove d'Exaerd. Thalamo-Nucleus Accumbens Projections in Motivated Behaviors and Addiction. Frontiers in systems neuroscience. vol 15. 2021-08-03. PMID:34335197. |
the ventral striatum, also called nucleus accumbens (nac), has long been known to integrate information from cortical, thalamic, midbrain and limbic nuclei to mediate goal-directed behaviors. |
2021-08-03 |
2023-08-13 |
Not clear |
| Salvatore Lecca, Frank Julius Meye, Massimo Trusel, Anna Tchenio, Julia Harris, Martin Karl Schwarz, Denis Burdakov, Francois Georges, Manuel Mamel. Aversive stimuli drive hypothalamus-to-habenula excitation to promote escape behavior. eLife. vol 6. 2018-05-14. PMID:28871962. |
nuclei including the lateral habenula (lhb), the lateral hypothalamus (lh), and the midbrain are not only reciprocally connected, but also respond to negative events contributing to goal-directed behaviors. |
2018-05-14 |
2023-08-13 |
mouse |
| Kim L Hoke, Eileen A Hebets, Daizaburo Shizuk. Neural Circuitry for Target Selection and Action Selection in Animal Behavior. Integrative and comparative biology. vol 57. issue 4. 2018-05-04. PMID:29048534. |
we use two examples-(1) spatial attention as an example of target selection in the vertebrate midbrain and (2) goal-directed locomotion as an example of action selection in the insect central complex-to further clarify neural circuit dynamics as they relate to target and action selection, and their interaction. |
2018-05-04 |
2023-08-13 |
Not clear |
| S N Habe. The place of dopamine in the cortico-basal ganglia circuit. Neuroscience. vol 282. 2018-01-26. PMID:25445194. |
the midbrain dopamine (da) neurons play a central role in developing appropriate goal-directed behaviors, including the motivation and cognition to develop appropriate actions to obtain a specific outcome. |
2018-01-26 |
2023-08-13 |
Not clear |
| Sarah X Luo, Leah Timbang, Jae-Ick Kim, Yulei Shang, Kadellyn Sandoval, Amy A Tang, Jennifer L Whistler, Jun B Ding, Eric J Huan. TGF-β Signaling in Dopaminergic Neurons Regulates Dendritic Growth, Excitatory-Inhibitory Synaptic Balance, and Reversal Learning. Cell reports. vol 17. issue 12. 2017-11-20. PMID:28009292. |
neural circuits involving midbrain dopaminergic (da) neurons regulate reward and goal-directed behaviors. |
2017-11-20 |
2023-08-13 |
mouse |
| Ruben A Tikidji-Hamburyan, Tarek A El-Ghazawi, Jason W Triplet. Novel Models of Visual Topographic Map Alignment in the Superior Colliculus. PLoS computational biology. vol 12. issue 12. 2017-05-22. PMID:28027309. |
the superior colliculus (sc) is a midbrain nucleus that integrates visual inputs from the retina and primary visual cortex (v1) to regulate goal-directed eye movements. |
2017-05-22 |
2023-08-13 |
mouse |
| Rachel J Sizemore, Rong Zhang, Naili Lin, Liping Goddard, Timothy Wastney, Louise C Parr-Brownlie, John N J Reynolds, Dorothy E Oorscho. Marked differences in the number and type of synapses innervating the somata and primary dendrites of midbrain dopaminergic neurons, striatal cholinergic interneurons, and striatal spiny projection neurons in the rat. The Journal of comparative neurology. vol 524. issue 5. 2016-10-24. PMID:26355230. |
elucidating the link between cellular activity and goal-directed behavior requires a fuller understanding of the mechanisms underlying burst firing in midbrain dopaminergic neurons and those that suppress activity during aversive or non-rewarding events. |
2016-10-24 |
2023-08-13 |
rat |
| Claudia Distler, Klaus-Peter Hoffman. Direct projections from the dorsal premotor cortex to the superior colliculus in the macaque (macaca mulatta). The Journal of comparative neurology. vol 523. issue 16. 2016-06-21. PMID:25921755. |
here we investigate the neuronal projections from the pmd to the midbrain superior colliculus (sc), which also contains reach-related neurons, to investigate how the sc integrates into a cortico-subcortical network responsible for initiation and modulation of goal-directed arm movements. |
2016-06-21 |
2023-08-13 |
monkey |
| Carmen N Lukie, Somayyeh Montazer-Hojat, Clay B Holroy. Developmental changes in the reward positivity: an electrophysiological trajectory of reward processing. Developmental cognitive neuroscience. vol 9. 2015-05-28. PMID:24879113. |
we propose that early development of the midbrain dopamine system facilitates the development of extended goal-directed behaviors in anterior cingulate cortex. |
2015-05-28 |
2023-08-13 |
Not clear |
| Brian J White, Robert A Marino, Susan E Boehnke, Laurent Itti, Jan Theeuwes, Douglas P Muno. Competitive integration of visual and goal-related signals on neuronal accumulation rate: a correlate of oculomotor capture in the superior colliculus. Journal of cognitive neuroscience. vol 25. issue 10. 2014-03-25. PMID:23691982. |
here, we examined how spatial proximity of competing stimuli shapes goal-directed responses in the superior colliculus (sc), a midbrain structure closely associated with the control of visual attention and eye movements. |
2014-03-25 |
2023-08-12 |
human |
| David M Cole, Christian F Beckmann, Graham E Searle, Christophe Plisson, Andri C Tziortzi, Thomas E Nichols, Roger N Gunn, Paul M Matthews, Eugenii A Rabiner, John D Beave. Orbitofrontal connectivity with resting-state networks is associated with midbrain dopamine D3 receptor availability. Cerebral cortex (New York, N.Y. : 1991). vol 22. issue 12. 2013-04-29. PMID:22186675. |
these findings demonstrate that differential interactions between ofc and networks implicated in cognitive control and reward are associated with midbrain d3r availability, consistent with the hypothesis that dopamine d3r signaling is an important molecular pathway underlying goal-directed behavior. |
2013-04-29 |
2023-08-12 |
human |