| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aqilah M McCane, Lo Kronheim, Alejandro Torrado Pacheco, Bita Moghadda. Adolescents rats engage the orbitofrontal-striatal pathway differently than adults during impulsive actions. Scientific reports. vol 14. issue 1. 2024-04-13. PMID:38615065. |
using chemogenetics, we identified orbitofrontal cortex (ofc) projections to the dorsomedial striatum (dms) as a critical pathway for age-related execution of impulsive actions. |
2024-04-13 |
2024-04-16 |
rat |
| Murad Atmaca, Muhammed Fatih Tabara, Mustafa Koc, Mehmet Gurkan Gurok, Sema Baykara, Sevda Korkmaz, Osman Merm. Cortical Thickness of the Orbitofrontal Cortex in Patients with Alcohol Use Disorder. Brain sciences. vol 13. issue 4. 2023-05-16. PMID:37190518. |
in the present study, it was hypothesised that compared to healthy control subjects, significant differences in the cortical thickness of the orbitofrontal cortex (ofc) region of the brain, which is relevant to both impulsivity and decision making, would be identified. |
2023-05-16 |
2023-08-14 |
human |
| Nicolò Trevisan, Fabio Di Camillo, Niccolò Ghiotto, Giulia Cattarinussi, Maddalena Sala, Fabio Sambatar. The complexity of cortical folding is reduced in chronic cocaine users. Addiction biology. vol 28. issue 3. 2023-02-24. PMID:36825487. |
we found that patients with cocaine addiction had greater impulsivity and showed reduced ccf in a cluster that encompassed the left insula and the supramarginal gyrus (smg) and in one in the left medial orbitofrontal cortex. |
2023-02-24 |
2023-08-14 |
Not clear |
| Nicolò Trevisan, Fabio Di Camillo, Niccolò Ghiotto, Giulia Cattarinussi, Maddalena Sala, Fabio Sambatar. The complexity of cortical folding is reduced in chronic cocaine users. Addiction biology. vol 28. issue 3. 2023-02-24. PMID:36825487. |
finally, the ccf in the left medial orbitofrontal cortex was correlated with the age of onset of cocaine addiction and with attentional impulsivity. |
2023-02-24 |
2023-08-14 |
Not clear |
| Hisashi Kamimura, Takahiro Matsuoka, Hiroshi Okai, Naoki Shimizu, Shu Harada, Koji Matsu. The associations between suicide-related behaviors, prefrontal dysfunction in emotional cognition, and personality traits in mood disorders. Scientific reports. vol 12. issue 1. 2022-10-17. PMID:36253452. |
the mdsa patients showed significantly high impulsivity and hopeless compared to healthy subjects, great response to the thread word task in the orbitofrontal cortex (ofc) and dorsolateral prefrontal cortex (dlpfc) compared to mdnsa patients, and the significant correlation between the personality traits and brain activation. |
2022-10-17 |
2023-08-14 |
human |
| Milena Girotti, Flavia R Carreno, David A Morila. Role of orbitofrontal cortex and differential effects of acute and chronic stress on motor impulsivity measured with the 1-choice serial reaction time test in male rats. The international journal of neuropsychopharmacology. 2022-09-10. PMID:36087292. |
role of orbitofrontal cortex and differential effects of acute and chronic stress on motor impulsivity measured with the 1-choice serial reaction time test in male rats. |
2022-09-10 |
2023-08-14 |
rat |
| Sara Garofalo, Luigi A E Degni, Manuela Sellitto, Davide Braghittoni, Francesca Starita, Sara Giovagnoli, Giuseppe di Pellegrino, Mariagrazia Benass. Unifying Evidence on Delay Discounting: Open Task, Analysis Tutorial, and Normative Data from an Italian Sample. International journal of environmental research and public health. vol 19. issue 4. 2022-02-25. PMID:35206238. |
the most used parameters in the literature to assess the delay discount rate were compared to find the most valid index to discriminate between normative data and a clinical population who typically present impulsivity issues, i.e., patients with a lesion to the medial orbitofrontal cortex (mofc). |
2022-02-25 |
2023-08-13 |
human |
| Kfir Feffer, Hyewon Helen Lee, Wei Wu, Amit Etkin, Ilya Demchenko, Terri Cairo, Frank Mazza, Peter Fettes, Farrokh Mansouri, Kamaldeep Bhui, Zafiris J Daskalakis, Daniel M Blumberger, Peter Giacobbe, Jonathan Downa. Dorsomedial prefrontal rTMS for depression in borderline personality disorder: a pilot randomized crossover trial. Journal of affective disorders. 2021-12-23. PMID:34942227. |
this study aimed primarily to assess the therapeutic effects of dorsomedial prefrontal cortex (dmpfc)-rtms against mdd symptoms in bpd patients, and secondarily to assess whether the therapeutic effects ensued via mechanisms of reduced impulsivity and core bpd pathology on clinical scales (bis-11, zan-bpd) or of reduced alpha- and theta-band activity on eeg recordings of right orbitofrontal cortex.. |
2021-12-23 |
2023-08-13 |
Not clear |
| Wendy K Adams, Dominique L Levesque, Paul J Cocker, Sukhbir Kaur, Tamara S Bodnar, Allan H Young, Catharine A Winstanle. Decreased motor impulsivity following chronic lithium treatment in male rats is associated with reduced levels of pro-inflammatory cytokines in the orbitofrontal cortex. Brain, behavior, and immunity. vol 89. 2021-04-27. PMID:32688024. |
decreased motor impulsivity following chronic lithium treatment in male rats is associated with reduced levels of pro-inflammatory cytokines in the orbitofrontal cortex. |
2021-04-27 |
2023-08-13 |
human |
| Hiroshi Kuniishi, Satoshi Ichisaka, Sae Matsuda, Eri Futora, Riho Harada, Yoshio Hat. Chronic Inactivation of the Orbitofrontal Cortex Increases Anxiety-Like Behavior and Impulsive Aggression, but Decreases Depression-Like Behavior in Rats. Frontiers in behavioral neuroscience. vol 10. 2020-10-01. PMID:28167902. |
chronic inactivation of the orbitofrontal cortex increases anxiety-like behavior and impulsive aggression, but decreases depression-like behavior in rats. |
2020-10-01 |
2023-08-13 |
rat |
| Marcos Ucha, David Roura-Martínez, Ana Contreras, Sheyla Pinto-Rivero, Javier Orihuel, Emilio Ambrosio, Alejandro Higuera-Mata. Impulsive Action and Impulsive Choice Are Differentially Associated With Gene Expression Variations of the GABA Frontiers in behavioral neuroscience. vol 13. 2020-10-01. PMID:30842730. |
impulsive action and impulsive choice are differentially associated with gene expression variations of the gaba the orbitofrontal cortex (ofc) is a key brain region for decision-making, action control and impulsivity. |
2020-10-01 |
2023-08-13 |
rat |
| Jin-Young Kim, Ji-Won Chun, Chang-Hyun Park, Hyun Cho, Jihye Choi, Siyun Yang, Kook-Jin Ahn, Dai Jin Ki. The Correlation between the Frontostriatal Network and Impulsivity in Internet Gaming Disorder. Scientific reports. vol 9. issue 1. 2020-08-19. PMID:30718701. |
this study was designed to investigate the altered resting-state functional connectivity (fc) of the bilateral orbitofrontal cortex (ofc) in igd participants and to examine its relationship with impulsivity compared with the normal controls (nc). |
2020-08-19 |
2023-08-13 |
human |
| Márcio Bonesso Alves, Daniela Pereira Laureano, Roberta Dalle Molle, Tania Diniz Machado, Ana Paula de Ascenção Salvador, Patrícia Maidana Miguel, Derek Lupinsky, Carla Dalmaz, Patrícia Pelufo Silveir. Intrauterine growth restriction increases impulsive behavior and is associated with altered dopamine transmission in both medial prefrontal and orbitofrontal cortex in female rats. Physiology & behavior. vol 204. 2020-05-04. PMID:30880239. |
intrauterine growth restriction increases impulsive behavior and is associated with altered dopamine transmission in both medial prefrontal and orbitofrontal cortex in female rats. |
2020-05-04 |
2023-08-13 |
rat |
| Wei Cheng, Edmund T Rolls, Trevor W Robbins, Weikang Gong, Zhaowen Liu, Wujun Lv, Jingnan Du, Hongkai Wen, Liang Ma, Erin Burke Quinlan, Hugh Garavan, Eric Artiges, Dimitri Papadopoulos Orfanos, Michael N Smolka, Gunter Schumann, Keith Kendrick, Jianfeng Fen. Decreased brain connectivity in smoking contrasts with increased connectivity in drinking. eLife. vol 8. 2020-04-10. PMID:30616717. |
increased impulsivity was found in smokers, associated with decreased functional connectivity of the non-reward-related lateral orbitofrontal cortex; and increased impulsivity was found in high amount drinkers, associated with increased functional connectivity of the reward-related medial orbitofrontal cortex. |
2020-04-10 |
2023-08-13 |
human |
| Zhiyan Wang, Lupeng Yue, Cailian Cui, Shuli Liu, Xuewei Wang, Yijing Li, Longyu M. Top-down control of the medial orbitofrontal cortex to nucleus accumbens core pathway in decisional impulsivity. Brain structure & function. vol 224. issue 7. 2020-02-18. PMID:31263945. |
top-down control of the medial orbitofrontal cortex to nucleus accumbens core pathway in decisional impulsivity. |
2020-02-18 |
2023-08-13 |
rat |
| Zhiyan Wang, Lupeng Yue, Cailian Cui, Shuli Liu, Xuewei Wang, Yijing Li, Longyu M. Top-down control of the medial orbitofrontal cortex to nucleus accumbens core pathway in decisional impulsivity. Brain structure & function. vol 224. issue 7. 2020-02-18. PMID:31263945. |
decisional impulsivity is one of the risk factors for occurrence and development of many mental disorders, and that the dysfunctions of orbitofrontal cortex (ofc) and nucleus accumbens core (nacc) are at least involved. |
2020-02-18 |
2023-08-13 |
rat |
| Emil F Coccaro, Daniel A Fitzgerald, Royce Lee, Michael McCloskey, K Luan Pha. Frontolimbic Morphometric Abnormalities in Intermittent Explosive Disorder and Aggression. Biological psychiatry. Cognitive neuroscience and neuroimaging. vol 1. issue 1. 2019-11-20. PMID:29560894. |
converging evidence from neuroimaging studies suggests that impulsive aggression, the core behavior in the dsm-5 diagnosis intermittent explosive disorder (ied), is regulated by frontolimbic brain structures, particularly orbitofrontal cortex, ventral medial prefrontal cortex, anterior cingulate cortex, amygdala, insula, and uncus. |
2019-11-20 |
2023-08-13 |
human |
| Luyi Zhou, Miranda L Fisher, Robert D Cole, Thomas J Gould, Vinay Parikh, Pavel I Ortinski, Jill R Turne. Neuregulin 3 Signaling Mediates Nicotine-Dependent Synaptic Plasticity in the Orbitofrontal Cortex and Cognition. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 43. issue 6. 2019-03-04. PMID:29114105. |
recent literature suggests that relapse to smoking is due to a lack of impulsive control, which is thought to be due to altered functioning within the orbitofrontal cortex (ofc). |
2019-03-04 |
2023-08-13 |
Not clear |
| Zahra Fatahi, Zahra Reisi, Gregor Rainer, Abbas Haghparast, Abbas Khan. Cannabinoids induce apathetic and impulsive patterns of choice through CB1 receptors and TRPV1 channels. Neuropharmacology. vol 133. 2018-11-13. PMID:29355640. |
in this study, we used effort-based and delay-based decision tasks and showed that acea, a potent cannabinoid agonist induced apathetic and impulsive patterns of choice in rats in a dose-dependent manner when locally injected into the anterior cingulate cortex (acc) and orbitofrontal cortex (ofc), respectively. |
2018-11-13 |
2023-08-13 |
rat |
| Cole Korponay, Daniela Dentico, Tammi Kral, Martina Ly, Ayla Kruis, Robin Goldman, Antoine Lutz, Richard J Davidso. Neurobiological correlates of impulsivity in healthy adults: Lower prefrontal gray matter volume and spontaneous eye-blink rate but greater resting-state functional connectivity in basal ganglia-thalamo-cortical circuitry. NeuroImage. vol 157. 2018-05-28. PMID:28602816. |
overall, we found that less gray matter in medial orbitofrontal cortex and paracingulate gyrus, greater resting-state functional connectivity between nodes of the basal ganglia-thalamo-cortical network, and lower spontaneous eye-blink rate were associated with greater impulsivity. |
2018-05-28 |
2023-08-13 |
Not clear |