| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Stefan Klöppel, Cynthia M Stonnington, Predrag Petrovic, Dean Mobbs, Oliver Tüscher, David Craufurd, Sarah J Tabrizi, Richard S J Frackowia. Irritability in pre-clinical Huntington's disease. Neuropsychologia. vol 48. issue 2. 2010-04-06. PMID:19878688. |
factor analysis suggests that irritability is related to impulsivity and aggression and is likely to engage the same neuronal circuits as these behaviours, including areas such as medial orbitofrontal cortex (ofc) and amygdala. |
2010-04-06 |
2023-08-12 |
human |
| Antonia S New, Erin A Hazlett, Randall E Newmark, Jane Zhang, Joseph Triebwasser, David Meyerson, Sophie Lazarus, Roanna Trisdorfer, Kim E Goldstein, Marianne Goodman, Harold W Koenigsberg, Janine D Flory, Larry J Siever, Monte S Buchsbau. Laboratory induced aggression: a positron emission tomography study of aggressive individuals with borderline personality disorder. Biological psychiatry. vol 66. issue 12. 2010-02-03. PMID:19748078. |
preclinical studies show that orbital frontal cortex (ofc) plays a role in regulating impulsive aggression. |
2010-02-03 |
2023-08-12 |
Not clear |
| Dawn M Eagle, Christelle Baune. Is there an inhibitory-response-control system in the rat? Evidence from anatomical and pharmacological studies of behavioral inhibition. Neuroscience and biobehavioral reviews. vol 34. issue 1. 2010-01-21. PMID:19615404. |
integration of these findings has pinpointed the orbitofrontal cortex (of), dorsomedial striatum (dmstr) and stn within a network that normally inhibits many forms of behavior, including both impulsive and compulsive forms. |
2010-01-21 |
2023-08-12 |
rat |
| Heather C Lasseter, Donna R Ramirez, Xiaohu Xie, Rita A Fuch. Involvement of the lateral orbitofrontal cortex in drug context-induced reinstatement of cocaine-seeking behavior in rats. The European journal of neuroscience. vol 30. issue 7. 2010-01-18. PMID:19769591. |
orbitofrontal cortex (ofc) damage produces impaired decision-making, impulsivity and perseveration and potentially contributes to compulsive drug seeking in cocaine users. |
2010-01-18 |
2023-08-12 |
rat |
| Koji Matsuo, Mark A Nicoletti, Marco A M Peluso, John P Hatch, Kiyotaka Nemoto, Yoshifumi Watanabe, Fabiano G Nery, E Serap Monkul, Giovana B Zunta-Soares, Charles L Bowden, Jair C Soare. Anterior cingulate volumes associated with trait impulsivity in individuals with bipolar disorder. Bipolar disorders. vol 11. issue 6. 2009-11-05. PMID:19689505. |
our previous study showed an inverse relationship between impulsivity and orbitofrontal cortex (ofc) volume in healthy subjects. |
2009-11-05 |
2023-08-12 |
human |
| Veena Kumari, Ian Barkataki, Sangeeta Goswami, Satinder Flora, Mrigendra Das, Pamela Taylo. Dysfunctional, but not functional, impulsivity is associated with a history of seriously violent behaviour and reduced orbitofrontal and hippocampal volumes in schizophrenia. Psychiatry research. vol 173. issue 1. 2009-08-19. PMID:19442493. |
our findings suggest that dysfunctional, but not functional, impulsivity is elevated in patients with schizophrenia with a propensity for repetitive violence, and this in turn appears to be associated with reduce volumes of both the orbitofrontal cortex grey matter and the hippocampus. |
2009-08-19 |
2023-08-12 |
human |
| Gerardo Maria de Araújo Filho, Andrea Parolin Jackowski, Katia Lin, Mirian S B Guaranha, Laura M F F Guilhoto, Henrique Hattori da Silva, Luís Otávio Sales Ferreira Caboclo, Henrique Carrete Júnior, Rodrigo Affonseca Bressan, Elza Márcia T Yacubia. Personality traits related to juvenile myoclonic epilepsy: MRI reveals prefrontal abnormalities through a voxel-based morphometry study. Epilepsy & behavior : E&B. vol 15. issue 2. 2009-08-11. PMID:19303459. |
structural alterations of the orbitofrontal cortex (ofc), involved in regulation of mood reactivity, impulsivity, and social behavior, were also observed. |
2009-08-11 |
2023-08-12 |
Not clear |
| Tim Hahn, Thomas Dresler, Ann-Christine Ehlis, Michael M Plichta, Sebastian Heinzel, Thomas Polak, Klaus-Peter Lesch, Felix Breuer, Peter M Jakob, Andreas J Fallgatte. Neural response to reward anticipation is modulated by Gray's impulsivity. NeuroImage. vol 46. issue 4. 2009-07-29. PMID:19328237. |
interindividual differences in gray's impulsivity accounted for a significant amount of variance of the reward-related bold-response in the ventral striatum and the orbitofrontal cortex. |
2009-07-29 |
2023-08-12 |
human |
| Koji Matsuo, Mark Nicoletti, Kiyotaka Nemoto, John P Hatch, Marco A M Peluso, Fabiano G Nery, Jair C Soare. A voxel-based morphometry study of frontal gray matter correlates of impulsivity. Human brain mapping. vol 30. issue 4. 2009-06-10. PMID:18465751. |
lesion and functional neuroimaging studies indicate that the ventromedial prefrontal region (vmpfc), including the orbitofrontal cortex (ofc), anterior cingulate cortex (acc) and medial prefrontal cortex, and the amygdala may modulate impulsivity and aggression. |
2009-06-10 |
2023-08-12 |
human |
| N D Volkow, J S Fowler, G J Wang, R Baler, F Telan. Imaging dopamine's role in drug abuse and addiction. Neuropharmacology. vol 56 Suppl 1. 2009-04-15. PMID:18617195. |
this decrease in dopamine function is associated with reduced regional activity in orbitofrontal cortex (involved in salience attribution; its disruption results in compulsive behaviors), cingulate gyrus (involved in inhibitory control; its disruption results in impulsivity) and dorsolateral prefrontal cortex (involved in executive function; its disruption results in impaired regulation of intentional actions). |
2009-04-15 |
2023-08-12 |
human |
| Catharine A Winstanley, Ryan K Bachtell, David E H Theobald, Samuel Laali, Thomas A Green, Arvind Kumar, Sumana Chakravarty, David W Self, Eric J Nestle. Increased impulsivity during withdrawal from cocaine self-administration: role for DeltaFosB in the orbitofrontal cortex. Cerebral cortex (New York, N.Y. : 1991). vol 19. issue 2. 2009-04-10. PMID:18539927. |
increased impulsivity during withdrawal from cocaine self-administration: role for deltafosb in the orbitofrontal cortex. |
2009-04-10 |
2023-08-12 |
rat |
| Catharine A Winstanley, Ryan K Bachtell, David E H Theobald, Samuel Laali, Thomas A Green, Arvind Kumar, Sumana Chakravarty, David W Self, Eric J Nestle. Increased impulsivity during withdrawal from cocaine self-administration: role for DeltaFosB in the orbitofrontal cortex. Cerebral cortex (New York, N.Y. : 1991). vol 19. issue 2. 2009-04-10. PMID:18539927. |
increased impulsivity caused by addictive drugs is believed to contribute to the maintenance of addiction and has been linked to hypofunction within the orbitofrontal cortex (ofc). |
2009-04-10 |
2023-08-12 |
rat |
| Lígia Aline Centenaro, Karin Vieira, Nicolle Zimmermann, Klaus A Miczek, Aldo Bolten Lucion, Rosa Maria Martins de Almeid. Social instigation and aggressive behavior in mice: role of 5-HT1A and 5-HT1B receptors in the prefrontal cortex. Psychopharmacology. vol 201. issue 2. 2009-03-24. PMID:18688602. |
an important site of action for these drugs is the ventral orbitofrontal cortex (vo pfc), an area of the brain which is particularly relevant in the inhibitory control of aggressive and impulsive behavior. |
2009-03-24 |
2023-08-12 |
mouse |
| Shirley Y Hill, Shuhui Wang, Bryan Kostelnik, Howard Carter, Brian Holmes, Michael McDermott, Nicholas Zezza, Scott Stiffler, Matcheri S Keshava. Disruption of orbitofrontal cortex laterality in offspring from multiplex alcohol dependence families. Biological psychiatry. vol 65. issue 2. 2009-03-20. PMID:18986649. |
the role of the orbitofrontal cortex (ofc) in regulating emotional processing is increasingly being recognized along with its association with impulsive behavior. |
2009-03-20 |
2023-08-12 |
Not clear |
| Ingmar H A Franken, Jan W van Strien, Ilse Nijs, Peter Muri. Impulsivity is associated with behavioral decision-making deficits. Psychiatry research. vol 158. issue 2. 2008-07-24. PMID:18215765. |
the findings add further evidence to the notion that trait impulsivity is associated with decision-making, a function of the orbitofrontal cortex. |
2008-07-24 |
2023-08-12 |
human |
| Mary M Torregrossa, Jennifer J Quinn, Jane R Taylo. Impulsivity, compulsivity, and habit: the role of orbitofrontal cortex revisited. Biological psychiatry. vol 63. issue 3. 2008-02-27. PMID:18194683. |
impulsivity, compulsivity, and habit: the role of orbitofrontal cortex revisited. |
2008-02-27 |
2023-08-12 |
Not clear |
| Catharine A Winstanle. The orbitofrontal cortex, impulsivity, and addiction: probing orbitofrontal dysfunction at the neural, neurochemical, and molecular level. Annals of the New York Academy of Sciences. vol 1121. 2008-02-04. PMID:17846162. |
the orbitofrontal cortex, impulsivity, and addiction: probing orbitofrontal dysfunction at the neural, neurochemical, and molecular level. |
2008-02-04 |
2023-08-12 |
Not clear |
| Nora D Volkow, Joanna S Fowler, Gene-Jack Wang, James M Swanson, Frank Telan. Dopamine in drug abuse and addiction: results of imaging studies and treatment implications. Archives of neurology. vol 64. issue 11. 2008-01-24. PMID:17998440. |
moreover, the reductions in d2 da receptors in the striatum are associated with reduced activity of the orbitofrontal cortex (region involved with salience attribution and motivation and with compulsive behaviors) and of the cingulate gyrus (region involved with inhibitory control and impulsivity), which implicates deregulation of frontal regions by da in the loss of control and compulsive drug intake that characterizes addiction. |
2008-01-24 |
2023-08-12 |
human |
| b' Vegard \\xc3\\x98ksendal Haaland, Nils Inge Landr\\xc3\\xb. Decision making as measured with the Iowa Gambling Task in patients with borderline personality disorder. Journal of the International Neuropsychological Society : JINS. vol 13. issue 4. 2007-08-31. PMID:17521489.' |
future studies should address whether those deficits are related to the behavioral characteristics of affective dysregulation and/or impulsivity, to the proposed dysfunctions and reduced volume of the orbitofrontal cortex and/or the amygdala, and to other neuropsychological functions. |
2007-08-31 |
2023-08-12 |
human |
| Bryon Adinoff, Mark J Williams, Susan E Best, Thomas S Harris, Patricia Chandler, Michael D Devou. Sex differences in medial and lateral orbitofrontal cortex hypoperfusion in cocaine-dependent men and women. Gender medicine. vol 3. issue 3. 2007-01-09. PMID:17081954. |
hypoperfusion of the orbitofrontal cortex (ofc) has previously been reported in individuals addicted to cocaine and has been posited as a biological mediator of relapse due to impulsivity or impaired decision making. |
2007-01-09 |
2023-08-12 |
Not clear |