| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shunta Goto, Natsuki Kojima, Miyu Komori, Noe Kawade, Kenzi Oshima, Daita Nadano, Nobumitsu Sasaki, Fumihiko Horio, Tsukasa Matsuda, Shinji Miyat. Vitamin C deficiency alters the transcriptome of the rat brain in a glucocorticoid-dependent manner, leading to microglial activation and reduced neurogenesis. The Journal of nutritional biochemistry. 2024-03-08. PMID:38458474. |
furthermore, vitc deficiency decreased the number of newly born neurons in the dentate gyrus of the hippocampus, suggesting that vitc was required for adult neurogenesis that plays a crucial role in learning and memory. |
2024-03-08 |
2024-03-11 |
rat |
| Daymara Mercerón-Martínez, Laura Alacán Ricardo, Arturo Bejerano Pina, Norma Orama Rojo, Ariel Expósito Seco, Yamilé Vega Hurtado, Bárbara Estupiñán Días, Isabel Fernández, Laura García Pupo, Marquiza Sablón Carrazana, Chryslaine Rodríguez-Tanty, Roberto Menéndez Soto Del Valle, William Almaguer-Melia. Amylovis-201 enhances physiological memory formation and rescues memory and hippocampal cell loss in a streptozotocin-induced Alzheimer's disease animal model. Brain research. 2024-03-03. PMID:38432261. |
in the first and third experiment, animals received a bilateral administration of streptozotocin and, starting 24 h after injection, a daily dose of amylovis-201 (orally), for 17 days or for the whole time of the experiment respectively (28 days), after which learning and memory, as well as the number of hippocampal dentate gyrus cells, were assessed. |
2024-03-03 |
2024-03-06 |
Not clear |
| Dingding Lv, Bin Xiao, Huaying Liu, Linping Wang, Yingshun Li, Yin Hua Zhang, Qinghua Ji. Enhanced NMDA receptor pathway and glutamate transmission in the hippocampal dentate gyrus mediate the spatial learning and memory impairment of obese rats. Pflugers Archiv : European journal of physiology. 2024-02-28. PMID:38416255. |
enhanced nmda receptor pathway and glutamate transmission in the hippocampal dentate gyrus mediate the spatial learning and memory impairment of obese rats. |
2024-02-28 |
2024-03-01 |
rat |
| Dingding Lv, Bin Xiao, Huaying Liu, Linping Wang, Yingshun Li, Yin Hua Zhang, Qinghua Ji. Enhanced NMDA receptor pathway and glutamate transmission in the hippocampal dentate gyrus mediate the spatial learning and memory impairment of obese rats. Pflugers Archiv : European journal of physiology. 2024-02-28. PMID:38416255. |
since glutamatergic transmission and nmda receptor neural pathways in hippocampal dentate gyrus (dg) are essential in the learning and memory, we aimed to investigate glutamate (glu) and nmda receptor signaling of dg in spatial learning and memory in diet-induced obesity (dio) rats. |
2024-02-28 |
2024-03-01 |
rat |
| Rebecca L Suthard, Ryan A Senne, Michelle D Buzharsky, Anh H Diep, Angela Y Pyo, Steve Ramire. Engram reactivation mimics cellular signatures of fear. Cell reports. vol 43. issue 3. 2024-02-24. PMID:38401120. |
to understand how artificial stimulation of fear affects intra-hippocampal neuron-astrocyte dynamics as well as their behavioral consequences, we express channelrhodopsin-2 in an activity-dependent manner within dentate gyrus neurons while recording both cell types with fiber photometry in hippocampal ventral ca1 across learning and memory. |
2024-02-24 |
2024-02-27 |
Not clear |
| Pan-Yue Deng, Ajeet Kumar, Valeria Cavalli, Vitaly A Klyachk. Circuit-based intervention corrects excessive dentate gyrus output in the fragile X mouse model. eLife. vol 12. 2024-02-13. PMID:38345852. |
the dentate gyrus is a brain area performing critical computations essential for learning and memory. |
2024-02-13 |
2024-02-15 |
mouse |
| Yue Qiao, Hang Liu, Chaoying He, Ying M. ApoE Mimic Peptide COG1410 reduces Aβ deposition and improves cognitive function by inducing the transformation of A1/ A2 reactive astrocytes and increasing the BDNF concentration in brain of APP/PS1 double transgenic mice. Neuroscience. 2023-11-25. PMID:38006963. |
in this study, we studied the effect of apoe mimetic peptide cog1410 on spatial learning and memory functions, deposition of aβ in the dentate gyrus (dg) of app/ps1 transgenic mice, and the different effects of a1 and a2 subtypes of reactive astrocytes. |
2023-11-25 |
2023-11-28 |
mouse |
| Pan-Yue Deng, Ajeet Kumar, Valeria Cavalli, Vitaly A Klyachk. Circuit-based intervention corrects excessive dentate gyrus output in the Fragile X mouse model. bioRxiv : the preprint server for biology. 2023-10-09. PMID:37808793. |
the dentate gyrus is a brain area performing critical computations essential for learning and memory. |
2023-10-09 |
2023-10-15 |
mouse |
| Xiaowei Li, Hong Wang, Qidi Zhang, Xiaobin Sun, Mengyuan Zhang, Gongming Wan. Inhibition of adult hippocampal neurogenesis induced by postoperative CD8 + T-cell infiltration is associated with cognitive decline later following surgery in adult mice. Journal of neuroinflammation. vol 20. issue 1. 2023-10-05. PMID:37798730. |
the subgranular zone of the dentate gyrus exhibits life-long neurogenesis, supporting hippocampus-dependent learning and memory. |
2023-10-05 |
2023-10-07 |
mouse |
| Gabriel Berdugo-Vega, Shonali Dhingra, Federico Calegar. Sharpening the blades of the dentate gyrus: how adult-born neurons differentially modulate diverse aspects of hippocampal learning and memory. The EMBO journal. 2023-09-25. PMID:37743770. |
sharpening the blades of the dentate gyrus: how adult-born neurons differentially modulate diverse aspects of hippocampal learning and memory. |
2023-09-25 |
2023-10-07 |
Not clear |
| Mikhail Stepanichev, Victor Aniol, Natalia Lazareva, Natalia Gulyaev. Decreased Hippocampal Neurogenesis in Aged Male Wistar Rats Is Not Associated with Memory Acquisition in a Water Maze. International journal of molecular sciences. vol 24. issue 17. 2023-09-09. PMID:37686083. |
this brain region is essential for learning and memory, and the lifelong neurogenesis occurring in the subgranular zone of the dentate gyrus may be a key event mediating the mnemonic functions of the hippocampus. |
2023-09-09 |
2023-10-07 |
rat |
| Mia Borzello, Steve Ramirez, Alessandro Treves, Inah Lee, Helen Scharfman, Craig Stark, James J Knierim, Lara M Range. Assessments of dentate gyrus function: discoveries and debates. Nature reviews. Neuroscience. 2023-06-14. PMID:37316588. |
there has been considerable speculation regarding the function of the dentate gyrus (dg) - a subregion of the mammalian hippocampus - in learning and memory. |
2023-06-14 |
2023-08-14 |
Not clear |
| Huimin Wei, Huimin Jiang, Yifan Zhou, Xuechun Xiao, Chen Zhou, Xunming J. Cerebral venous congestion alters brain metabolite profiles, impairing cognitive function. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2023-06-13. PMID:37309740. |
using cerebral venous congestion rat models, we found these rats exhibited decreased long-term potentiation (ltp) in the hippocampal dentate gyrus and impaired spatial learning and memory. |
2023-06-13 |
2023-08-14 |
rat |
| Camille M Fun. Effects of intrauterine growth restriction on embryonic hippocampal dentate gyrus neurogenesis and postnatal critical period of synaptic plasticity that govern learning and memory function. Frontiers in neuroscience. vol 17. 2023-04-03. PMID:37008232. |
effects of intrauterine growth restriction on embryonic hippocampal dentate gyrus neurogenesis and postnatal critical period of synaptic plasticity that govern learning and memory function. |
2023-04-03 |
2023-08-14 |
mouse |
| Camille M Fun. Effects of intrauterine growth restriction on embryonic hippocampal dentate gyrus neurogenesis and postnatal critical period of synaptic plasticity that govern learning and memory function. Frontiers in neuroscience. vol 17. 2023-04-03. PMID:37008232. |
the hippocampus, composed of the dentate gyrus (dg) and cornu ammonis (ca) subregions, is an important gray matter structure critical to learning and memory, and is particularly vulnerable to the chronic hypoxic-ischemic effects of upi. |
2023-04-03 |
2023-08-14 |
mouse |
| Yujuan Zhou, Xu Wang, Yingying Liu, Yulu Gu, Renjun Gu, Geng Zhang, Qing Li. Mechanisms of abnormal adult hippocampal neurogenesis in Alzheimer's disease. Frontiers in neuroscience. vol 17. 2023-03-06. PMID:36875663. |
the dentate gyrus of the hippocampus is a key area for learning and memory functions, and an important site of adult hippocampal neurogenesis (ahn) in normal mammals. |
2023-03-06 |
2023-08-14 |
Not clear |
| Qiaoyi Sun, Li Ma, Jing Qiao, Xing Wang, Jianguo Li, Yuxi Wang, Ailing Tan, Zihui Ye, Yukang Wu, Jiajie Xi, Jiuhong Kan. MiR-181a-5p promotes neural stem cell proliferation and enhances the learning and memory of aged mice. Aging cell. 2023-02-16. PMID:36797653. |
moreover, overexpression of mir-181a-5p in the dentate gyrus enhanced the proliferation of nscs and ameliorated learning and memory impairments in aged mice. |
2023-02-16 |
2023-08-14 |
mouse |
| Kathrin Barth, Verica Vasić, Brennan McDonald, Nora Heinig, Marc-Christoph Wagner, Ulrike Schumann, Cora Röhlecke, Frank Bicker, Lana Schumann, Konstantin Radyushkin, Jan Baumgart, Stefan Tenzer, Frauke Zipp, Matthias Meinhardt, Kari Alitalo, Irmgard Tegeder, Mirko H H Schmid. EGFL7 loss correlates with increased VEGF-D expression, upregulating hippocampal adult neurogenesis and improving spatial learning and memory. Cellular and molecular life sciences : CMLS. vol 80. issue 2. 2023-01-30. PMID:36715759. |
throughout adulthood, these cells give rise to neurons in the dentate gyrus, playing an important role in learning and memory. |
2023-01-30 |
2023-08-14 |
mouse |
| Qi Zhang, Shun-Jiang X. [Contributions of impaired adult hippocampal neurogenesis to occurrence and development of diabetic encephalopathy]. Sheng li xue bao : [Acta physiologica Sinica]. vol 74. issue 5. 2022-11-01. PMID:36319106. |
the dentate gyrus (dg) of hippocampus is a crucial region for learning and memory, as well as adult neurogenesis in mammals. |
2022-11-01 |
2023-08-14 |
Not clear |
| Jing Lyu, Cong Min Wang, Xin Liu, Ji Lin Ya. [Effects of beta adrenergic receptor in hippocampal dentate gyrus on spatial learning and memory in sleep deprived rats and its mechanisms]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 38. issue 3. 2022-09-05. PMID:36062792. |
[effects of beta adrenergic receptor in hippocampal dentate gyrus on spatial learning and memory in sleep deprived rats and its mechanisms]. |
2022-09-05 |
2023-08-14 |
rat |