| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jun Li, Anping Chai, Lifang Wang, Yuanlin Ma, Zhiliu Wu, Hao Yu, Liwei Mei, Lin Lu, Chen Zhang, Weihua Yue, Lin Xu, Yi Rao, Dai Zhan. Synaptic P-Rex1 signaling regulates hippocampal long-term depression and autism-like social behavior. Proceedings of the National Academy of Sciences of the United States of America. vol 112. issue 50. 2016-06-03. PMID:26621702. |
genetic deletion or knockdown of p-rex1 in the ca1 region of the hippocampus in mice resulted in autism-like social behavior that was specifically linked to the defect of long-term depression (ltd) in the ca1 region through alteration of ampa receptor endocytosis mediated by the postsynaptic pp1α (protein phosphase 1α)-p-rex1-rac1 (ras-related c3 botulinum toxin substrate 1) signaling pathway. |
2016-06-03 |
2023-08-13 |
mouse |
| Andrew R Gallimore, A Radu Aricescu, Michisuke Yuzaki, Radu Calinesc. A Computational Model for the AMPA Receptor Phosphorylation Master Switch Regulating Cerebellar Long-Term Depression. PLoS computational biology. vol 12. issue 1. 2016-05-11. PMID:26807999. |
a computational model for the ampa receptor phosphorylation master switch regulating cerebellar long-term depression. |
2016-05-11 |
2023-08-13 |
Not clear |
| Felipe C Ribeiro, Luis E Santos, Sergio T Ferreir. USP46: a new piece of the memory puzzle? Journal of neurochemistry. vol 134. issue 6. 2015-12-15. PMID:26237995. |
long-term potentiation (ltp) and long-term depression (ltd) are crucial for synaptic plasticity, and are driven by ampa receptor (ampar) trafficking. |
2015-12-15 |
2023-08-13 |
Not clear |
| Y Yu, D-Q Cao, H-Y Xu, M Sun, Z-L Huang, W-H Yung, N Lu, Y Huan. 5-HT3A receptors are required in long-term depression and AMPA receptor internalization. Neuroscience. vol 278. 2015-10-20. PMID:25130560. |
5-ht3a receptors are required in long-term depression and ampa receptor internalization. |
2015-10-20 |
2023-08-13 |
mouse |
| Yan Li, Alan L Pehrson, Jessica A Waller, Elena Dale, Connie Sanchez, Maria Gulinell. A critical evaluation of the activity-regulated cytoskeleton-associated protein (Arc/Arg3.1)'s putative role in regulating dendritic plasticity, cognitive processes, and mood in animal models of depression. Frontiers in neuroscience. vol 9. 2015-08-31. PMID:26321903. |
the effects on ampa receptor trafficking are likely related to arc's ability to modulate phenomena such as long-term potentiation, long-term depression, and synaptic scaling, each of which are important for maintaining proper cognitive function. |
2015-08-31 |
2023-08-13 |
Not clear |
| Boeke J van Beugen, Xin Qiao, Dana H Simmons, Chris I De Zeeuw, Christian Hanse. Enhanced AMPA receptor function promotes cerebellar long-term depression rather than potentiation. Learning & memory (Cold Spring Harbor, N.Y.). vol 21. issue 12. 2015-07-16. PMID:25403454. |
enhanced ampa receptor function promotes cerebellar long-term depression rather than potentiation. |
2015-07-16 |
2023-08-13 |
Not clear |
| Z M Jeanes, T R Buske, R A Morriset. Cell type-specific synaptic encoding of ethanol exposure in the nucleus accumbens shell. Neuroscience. vol 277. 2015-06-08. PMID:25003712. |
we observed low frequency-induced long-term depression (1hz-ltd) of α-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid (ampa)-mediated excitatory postsynaptic currents (epscs) solely in d1+ msns. |
2015-06-08 |
2023-08-13 |
mouse |
| Chien-Wei Lin, Lun-Ching Chang, George C Tseng, Caitlin M Kirkwood, Etienne L Sibille, Robert A Swee. VSNL1 Co-Expression Networks in Aging Include Calcium Signaling, Synaptic Plasticity, and Alzheimer's Disease Pathways. Frontiers in psychiatry. vol 6. 2015-03-25. PMID:25806004. |
vsnl1 was significantly co-expressed with genes in pathways for calcium signaling, ad, long-term potentiation, long-term depression, and trafficking of ampa receptors. |
2015-03-25 |
2023-08-13 |
human |
| G A Grigorya. [Role of glycogen synthase kinase-3 in mechanisms of learning and memory]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 63. issue 5. 2014-12-31. PMID:25438579. |
the data on participation of gsk-3b in regulation of nmda-dependent long-term depression and potentiation, and the possible mechanisms of enzyme's influence through nmda receptors and ampa endocytosis are shown. |
2014-12-31 |
2023-08-13 |
Not clear |
| Fergil Mills, Thomas E Bartlett, Lasse Dissing-Olesen, Marta B Wisniewska, Jacek Kuznicki, Brian A Macvicar, Yu Tian Wang, Shernaz X Bamj. Cognitive flexibility and long-term depression (LTD) are impaired following β-catenin stabilization in vivo. Proceedings of the National Academy of Sciences of the United States of America. vol 111. issue 23. 2014-09-30. PMID:24912177. |
in accordance with these deficits, β-catenin stabilization was found to abolish long-term depression by stabilizing cadherin at the synaptic membrane and impairing ampa receptor endocytosis, while leaving basal synaptic transmission and long-term potentiation unaffected. |
2014-09-30 |
2023-08-13 |
mouse |
| Hyejin Lee, Eun-Jae Lee, Yoo Sung Song, Eunjoon Ki. Long-term depression-inducing stimuli promote cleavage of the synaptic adhesion molecule NGL-3 through NMDA receptors, matrix metalloproteinases and presenilin/γ-secretase. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 369. issue 1633. 2014-08-11. PMID:24298159. |
long-term depression (ltd) reduces the functional strength of excitatory synapses through mechanisms that include the removal of ampa glutamate receptors from the postsynaptic membrane. |
2014-08-11 |
2023-08-12 |
Not clear |
| Meng-Hsuan Han, Song Jiao, Jie-Min Jia, Yong Chen, Cai Yun Chen, Marjan Gucek, Sanford P Markey, Zheng L. The novel caspase-3 substrate Gap43 is involved in AMPA receptor endocytosis and long-term depression. Molecular & cellular proteomics : MCP. vol 12. issue 12. 2014-07-31. PMID:24023391. |
the novel caspase-3 substrate gap43 is involved in ampa receptor endocytosis and long-term depression. |
2014-07-31 |
2023-08-12 |
Not clear |
| Meng-Hsuan Han, Song Jiao, Jie-Min Jia, Yong Chen, Cai Yun Chen, Marjan Gucek, Sanford P Markey, Zheng L. The novel caspase-3 substrate Gap43 is involved in AMPA receptor endocytosis and long-term depression. Molecular & cellular proteomics : MCP. vol 12. issue 12. 2014-07-31. PMID:24023391. |
the cysteine protease caspase-3, best known as an executioner of cell death in apoptosis, also plays a non-apoptotic role in n-methyl-d-aspartate receptor-dependent long-term depression of synaptic transmission (nmdar-ltd) and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) receptor endocytosis in neurons. |
2014-07-31 |
2023-08-12 |
Not clear |
| Shinji Matsuda, Wataru Kakegawa, Timotheus Budisantoso, Toshihiro Nomura, Kazuhisa Kohda, Michisuke Yuzak. Stargazin regulates AMPA receptor trafficking through adaptor protein complexes during long-term depression. Nature communications. vol 4. 2014-06-19. PMID:24217640. |
stargazin regulates ampa receptor trafficking through adaptor protein complexes during long-term depression. |
2014-06-19 |
2023-08-12 |
Not clear |
| Graham L Collingridge, Stephane Peinea. Strippers reveal their depressing secrets: removing AMPA receptors. Neuron. vol 82. issue 1. 2014-06-02. PMID:24698263. |
(2014) describe a novel form of long-term depression of ampa receptor-mediated synaptic transmission in the hippocampus involving the activation of microglia. |
2014-06-02 |
2023-08-13 |
Not clear |
| Erica W Taylor, Kai Wang, Amy R Nelson, Teruko M Bredemann, Kyle B Fraser, Sarah M Clinton, Rosemary Puckett, Richard B Marchase, John C Chatham, Lori L McMaho. O-GlcNAcylation of AMPA receptor GluA2 is associated with a novel form of long-term depression at hippocampal synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 1. 2014-02-24. PMID:24381264. |
o-glcnacylation of ampa receptor glua2 is associated with a novel form of long-term depression at hippocampal synapses. |
2014-02-24 |
2023-08-12 |
rat |
| Silvia Middei, Gry Houeland, Virve Cavallucci, Martine Ammassari-Teule, Marcello D'Amelio, Hélène Mari. CREB is necessary for synaptic maintenance and learning-induced changes of the AMPA receptor GluA1 subunit. Hippocampus. vol 23. issue 6. 2014-02-10. PMID:23504989. |
these molecular alterations correlated with a reduction in ampa receptors mepsc frequency, with a decrease in long-term potentiation (ltp), and with an increase in long-term depression (ltd). |
2014-02-10 |
2023-08-12 |
mouse |
| Victor Anggono, Yeliz Koç-Schmitz, Jocelyn Widagdo, Jan Kormann, Annie Quan, Chih-Ming Chen, Phillip J Robinson, Se-Young Choi, David J Linden, Markus Plomann, Richard L Hugani. PICK1 interacts with PACSIN to regulate AMPA receptor internalization and cerebellar long-term depression. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 34. 2013-11-26. PMID:23918399. |
pick1 interacts with pacsin to regulate ampa receptor internalization and cerebellar long-term depression. |
2013-11-26 |
2023-08-12 |
Not clear |
| Julien Pierre Dupuis, Michael Feyder, Cristina Miguelez, Liliana Garcia, Stéphanie Morin, Daniel Choquet, Eric Hosy, Erwan Bezard, Gilberto Fisone, Bernard H Bioulac, Jérôme Baufreto. Dopamine-dependent long-term depression at subthalamo-nigral synapses is lost in experimental parkinsonism. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 36. 2013-11-15. PMID:24005286. |
using whole-cell patch-clamp in acute rat brain slices, we describe a molecular pathway supporting an activity-dependent long-term depression of stn-snr synapses through an nmdar-and d1/5 dopamine receptor-mediated endocytosis of synaptic ampa glutamate receptors. |
2013-11-15 |
2023-08-12 |
rat |
| Marion Benoist, Rocío Palenzuela, Carlos Rozas, Patricio Rojas, Elena Tortosa, Bernardo Morales, Christian González-Billault, Jesús Ávila, José A Esteba. MAP1B-dependent Rac activation is required for AMPA receptor endocytosis during long-term depression. The EMBO journal. vol 32. issue 16. 2013-10-31. PMID:23881099. |
map1b-dependent rac activation is required for ampa receptor endocytosis during long-term depression. |
2013-10-31 |
2023-08-12 |
mouse |