| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daniel L Rocca, Mascia Amici, Anna Antoniou, Elena Blanco Suarez, Nagaraj Halemani, Kai Murk, Jennifer McGarvey, Nadia Jaafari, Jack R Mellor, Graham L Collingridge, Jonathan G Hanle. The small GTPase Arf1 modulates Arp2/3-mediated actin polymerization via PICK1 to regulate synaptic plasticity. Neuron. vol 79. issue 2. 2013-10-17. PMID:23889934. |
inhibition of arp2/3-mediated actin polymerization by pick1 is a central mechanism to ampa receptor (ampar) internalization and long-term depression (ltd), although the signaling pathways that modulate this process in response to nmda receptor (nmdar) activation are unknown. |
2013-10-17 |
2023-08-12 |
Not clear |
| Roger L Clem, Richard L Hugani. Norepinephrine enhances a discrete form of long-term depression during fear memory storage. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 29. 2013-09-27. PMID:23864672. |
previous work identified lateral amygdala (la) calcium-permeable ampa receptors (cp-ampars) as a key target for synaptic removal in long-term depression (ltd) and persistent fear attenuation. |
2013-09-27 |
2023-08-12 |
mouse |
| Ying-Lin Chen, Che-Kun James She. Modulation of mGluR-dependent MAP1B translation and AMPA receptor endocytosis by microRNA miR-146a-5p. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 21. 2013-08-09. PMID:23699512. |
the translation of dendritic microtubule-associated protein 1b (map1b) is exaggerated upon group i mglur activation leading to ampa receptor (ampar) endocytosis and consequent long-term depression. |
2013-08-09 |
2023-08-12 |
mouse |
| Kazuhisa Kohda, Wataru Kakegawa, Shinji Matsuda, Tadashi Yamamoto, Hisashi Hirano, Michisuke Yuzak. The δ2 glutamate receptor gates long-term depression by coordinating interactions between two AMPA receptor phosphorylation sites. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 10. 2013-05-02. PMID:23431139. |
the δ2 glutamate receptor gates long-term depression by coordinating interactions between two ampa receptor phosphorylation sites. |
2013-05-02 |
2023-08-12 |
Not clear |
| Gayle H Doherty, Dayne Beccano-Kelly, Shi Du Yan, Frank J Gunn-Moore, Jenni Harve. Leptin prevents hippocampal synaptic disruption and neuronal cell death induced by amyloid β. Neurobiology of aging. vol 34. issue 1. 2013-04-23. PMID:22921154. |
moreover leptin inhibits aβ(1-42)-driven facilitation of long-term depression and internalization of the 2-amino-3-(5-methyl-3-oxo-1,2- oxazol-4-yl)propanoic acid (ampa) receptor subunit, glur1, via activation of pi3-kinase. |
2013-04-23 |
2023-08-12 |
rat |
| Jian-Ping Zhao, Yasunobu Murata, Martha Constantine-Pato. Eye opening and PSD95 are required for long-term potentiation in developing superior colliculus. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 2. 2013-03-07. PMID:23267080. |
psd95 knockdown (kd) in vivo blocks this ltp, but not long-term depression, and reduces frequencies of miniature ampa receptor and nmdar currents with no change in presynaptic release. |
2013-03-07 |
2023-08-12 |
Not clear |
| Takuya Sasaki, Kaoru Beppu, Kenji F Tanaka, Yugo Fukazawa, Ryuichi Shigemoto, Ko Matsu. Application of an optogenetic byway for perturbing neuronal activity via glial photostimulation. Proceedings of the National Academy of Sciences of the United States of America. vol 109. issue 50. 2013-02-28. PMID:23185019. |
using slice preparations, we show that glial photostimulation leads to release of glutamate, which was sufficient to activate ampa receptors on purkinje cells and to induce long-term depression of parallel fiber-to-purkinje cell synapses through activation of metabotropic glutamate receptors. |
2013-02-28 |
2023-08-12 |
mouse |
| Mohammad Shehata, Hiroyuki Matsumura, Reiko Okubo-Suzuki, Noriaki Ohkawa, Kaoru Inokuch. Neuronal stimulation induces autophagy in hippocampal neurons that is involved in AMPA receptor degradation after chemical long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 30. 2012-10-29. PMID:22836274. |
neuronal stimulation induces autophagy in hippocampal neurons that is involved in ampa receptor degradation after chemical long-term depression. |
2012-10-29 |
2023-08-12 |
mouse |
| Mohammad Shehata, Hiroyuki Matsumura, Reiko Okubo-Suzuki, Noriaki Ohkawa, Kaoru Inokuch. Neuronal stimulation induces autophagy in hippocampal neurons that is involved in AMPA receptor degradation after chemical long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 30. 2012-10-29. PMID:22836274. |
brief low-dose nmda, a model of chemical long-term depression (chem-ltd), increased lc3-ii with a time course coincident with akt and mammalian target of rapamycin (mtor) dephosphorylation and degradation of glur1, an ampa receptor (ampar) subunit. |
2012-10-29 |
2023-08-12 |
mouse |
| Kathryn M Murphy, Lilia Tcharnaia, Simon P Beshara, David G Jone. Cortical development of AMPA receptor trafficking proteins. Frontiers in molecular neuroscience. vol 5. 2012-10-02. PMID:22623912. |
changes in the number of ampa receptors and time spent at the synaptic surface are important factors of plasticity that directly affect long-term potentiation (ltp), long-term depression (ltd), synaptic scaling, and the excitatory-inhibitory (e/i) balance in the developing cortex. |
2012-10-02 |
2023-08-12 |
rat |
| Gabriela Antunes, Erik De Schutte. A stochastic signaling network mediates the probabilistic induction of cerebellar long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 27. 2012-09-18. PMID:22764236. |
cerebellar long-term depression (ltd) is a form of synaptic plasticity expressed as a reduction in the number of synaptic ampa receptors (ampars) in purkinje cells. |
2012-09-18 |
2023-08-12 |
Not clear |
| Brittany N Cazakoff, John G Howlan. AMPA receptor endocytosis in rat perirhinal cortex underlies retrieval of object memory. Learning & memory (Cold Spring Harbor, N.Y.). vol 18. issue 11. 2012-02-27. PMID:22005749. |
mechanisms consistent with long-term depression in the perirhinal cortex (prh) play a fundamental role in object recognition memory; however, whether ampa receptor endocytosis is involved in distinct phases of recognition memory is not known. |
2012-02-27 |
2023-08-12 |
rat |
| Peter van der Sluijs, Casper C Hoogenraa. New insights in endosomal dynamics and AMPA receptor trafficking. Seminars in cell & developmental biology. vol 22. issue 5. 2012-01-26. PMID:21843653. |
on induction of synaptic plasticity, internalized ampa receptors undergo endosomal sorting and cycle through early endosomes and recycling endosomes back to the plasma membrane (model for long-term potentiation) or target for degradation to the lysosomes (model for long-term depression). |
2012-01-26 |
2023-08-12 |
Not clear |
| Hey-Kyoung Lee, Alfredo Kirkwoo. AMPA receptor regulation during synaptic plasticity in hippocampus and neocortex. Seminars in cell & developmental biology. vol 22. issue 5. 2012-01-26. PMID:21856433. |
at least for the postsynaptic forms of ltp and long-term depression (ltd), regulation of ampa receptors (ampars) has emerged as a key mechanism. |
2012-01-26 |
2023-08-12 |
rabbit |
| Thomas M Sanderson, Graham L Collingridge, Stephen M Fitzjoh. Differential trafficking of AMPA receptors following activation of NMDA receptors and mGluRs. Molecular brain. vol 4. 2011-11-15. PMID:21794146. |
the removal of ampa receptors from synapses is a major component of long-term depression (ltd). |
2011-11-15 |
2023-08-12 |
Not clear |
| Kaiwen He, Angela Lee, Lihua Song, Patrick O Kanold, Hey-Kyoung Le. AMPA receptor subunit GluR1 (GluA1) serine-845 site is involved in synaptic depression but not in spine shrinkage associated with chemical long-term depression. Journal of neurophysiology. vol 105. issue 4. 2011-09-29. PMID:21307330. |
ampa receptor subunit glur1 (glua1) serine-845 site is involved in synaptic depression but not in spine shrinkage associated with chemical long-term depression. |
2011-09-29 |
2023-08-12 |
mouse |
| A Vazdarjanova, K Bunting, N Muthusamy, C Bergso. Calcyon upregulation in adolescence impairs response inhibition and working memory in adulthood. Molecular psychiatry. vol 16. issue 6. 2011-09-19. PMID:21403673. |
calcyon regulates activity-dependent internalization of α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate (ampa) glutamate receptors and long-term depression of excitatory synapses. |
2011-09-19 |
2023-08-12 |
mouse |
| Jianmin Zhang, Yue Wang, Zhikai Chi, Matthew J Keuss, Ying-Min Emily Pai, Ho Chul Kang, Joo-Ho Shin, Artem Bugayenko, Hong Wang, Yulan Xiong, Mikhail V Pletnikov, Mark P Mattson, Ted M Dawson, Valina L Dawso. The AAA+ ATPase Thorase regulates AMPA receptor-dependent synaptic plasticity and behavior. Cell. vol 145. issue 2. 2011-06-09. PMID:21496646. |
the synaptic insertion or removal of ampa receptors (ampar) plays critical roles in the regulation of synaptic activity reflected in the expression of long-term potentiation (ltp) and long-term depression (ltd). |
2011-06-09 |
2023-08-12 |
mouse |
| Sofia Jürgensen, Leandro L Antonio, Gabriela E A Mussi, Jordano Brito-Moreira, Theresa R Bomfim, Fernanda G De Felice, Emilio R Garrido-Sanabria, Ésper A Cavalheiro, Sergio T Ferreir. Activation of D1/D5 dopamine receptors protects neurons from synapse dysfunction induced by amyloid-beta oligomers. The Journal of biological chemistry. vol 286. issue 5. 2011-03-21. PMID:21115476. |
aβos have been shown to impact synapse function by inhibiting long term potentiation, facilitating the induction of long term depression and inducing internalization of both ampa and nmda glutamate receptors, critical players in plasticity mechanisms. |
2011-03-21 |
2023-08-12 |
Not clear |
| S Y Yu, D C Wu, R Z Zha. GluN2B subunits of the NMDA receptor contribute to the AMPA receptor internalization during long-term depression in the lateral amygdala of juvenile rats. Neuroscience. vol 171. issue 4. 2011-03-10. PMID:20884329. |
glun2b subunits of the nmda receptor contribute to the ampa receptor internalization during long-term depression in the lateral amygdala of juvenile rats. |
2011-03-10 |
2023-08-12 |
rat |