| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C K Thoeringer, U J Pfeiffer, G Rammes, F A Pamplona, S Moosmang, C T Wotja. Early life environment determines the development of adult phobic-like fear responses in BALB/cAnN mice. Genes, brain, and behavior. vol 9. issue 8. 2011-03-02. PMID:20659172. |
increased susceptibility for developing exaggerated fear responses was accompanied by decreased long-term depression and increased surface trafficking of the ampa receptor glur1 subunit at the level of the basolateral amygdala complex. |
2011-03-02 |
2023-08-12 |
mouse |
| Rüdiger Rudolf, Claudia Margarethe Bittins, Hans-Hermann Gerde. The role of myosin V in exocytosis and synaptic plasticity. Journal of neurochemistry. vol 116. issue 2. 2011-01-20. PMID:21077886. |
this review focuses on the role of myosin v in (i) axonal transport and stimulated exocytosis of large dense-core vesicles to regulate the secretion of neuroactive substances, (ii) tethering of the endoplasmic reticulum at cerebellar synapses to permit long-term depression, (iii) recycling of α-amino-3-hydroxy-5-methylisoxazole-4-propionate (ampa) receptors at hippocampal synapses during long-term potentiation, and (iv) recycling of nicotinic acetylcholine receptors at the neuromuscular junction. |
2011-01-20 |
2023-08-12 |
Not clear |
| Zachary M Jeanes, Tavanna R Buske, Richard A Morriset. In vivo chronic intermittent ethanol exposure reverses the polarity of synaptic plasticity in the nucleus accumbens shell. The Journal of pharmacology and experimental therapeutics. vol 336. issue 1. 2011-01-18. PMID:20947635. |
synaptic conditioning (low-frequency stimulation with concurrent postsynaptic depolarization) reliably depressed ampa epscs by nearly 30%; this accumbal long-term depression (ltd) was blocked by a nonselective n-methyl-d-aspartate (nmda) receptor antagonist (dl-2-amino-5-phosphonovaleric acid) and a selective nmda receptor 2b antagonist [r-(r*,s*)-α-(4-hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidine propanol]. |
2011-01-18 |
2023-08-12 |
mouse |
| Ami Citri, Samarjit Bhattacharyya, Cong Ma, Wade Morishita, Scarlett Fang, Josep Rizo, Robert C Malenk. Calcium binding to PICK1 is essential for the intracellular retention of AMPA receptors underlying long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 49. 2011-01-07. PMID:21147983. |
calcium binding to pick1 is essential for the intracellular retention of ampa receptors underlying long-term depression. |
2011-01-07 |
2023-08-12 |
Not clear |
| Ami Citri, Samarjit Bhattacharyya, Cong Ma, Wade Morishita, Scarlett Fang, Josep Rizo, Robert C Malenk. Calcium binding to PICK1 is essential for the intracellular retention of AMPA receptors underlying long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 49. 2011-01-07. PMID:21147983. |
nmda receptor (nmdar)-dependent long-term depression (ltd) in the hippocampus is mediated primarily by the calcium-dependent removal of ampa receptors (ampars) from the postsynaptic density. |
2011-01-07 |
2023-08-12 |
Not clear |
| Brad A Grueter, Gabor Brasnjo, Robert C Malenk. Postsynaptic TRPV1 triggers cell type-specific long-term depression in the nucleus accumbens. Nature neuroscience. vol 13. issue 12. 2011-01-06. PMID:21076424. |
using bacterial artificial chromosome transgenic mice, we found that synaptic activation of group i metabotropic glutamate receptors in nac msns in the indirect, but not direct, pathway led to the production of endocannabinoids, which activated presynaptic cb1 receptors to trigger endocannabinoid-mediated long-term depression (ecb-ltd) as well as postsynaptic transient receptor potential vanilloid 1 (trpv1) channels to trigger a form of ltd resulting from endocytosis of ampa receptors. |
2011-01-06 |
2023-08-12 |
mouse |
| Lauren E McElvain, Martha W Bagnall, Alexandra Sakatos, Sascha du La. Bidirectional plasticity gated by hyperpolarization controls the gain of postsynaptic firing responses at central vestibular nerve synapses. Neuron. vol 68. issue 4. 2011-01-06. PMID:21092864. |
pairing nerve activity with changes in postsynaptic voltage induced bidirectional synaptic plasticity in vestibular nucleus projection neurons: long-term potentiation relied on calcium-permeable ampa receptors and postsynaptic hyperpolarization, whereas long-term depression relied on nmda receptors and postsynaptic depolarization. |
2011-01-06 |
2023-08-12 |
Not clear |
| Cameron H Good, Carl R Lupic. Afferent-specific AMPA receptor subunit composition and regulation of synaptic plasticity in midbrain dopamine neurons by abused drugs. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 23. 2010-08-24. PMID:20534838. |
using a unique rat brain slice preparation, we found that ppn stimulation activates afferents targeting glur2-containing ampa receptors (ampar) on vta da neurons, and these afferents did not exhibit long-term depression (ltd). |
2010-08-24 |
2023-08-12 |
rat |
| Yi Peng, Jiang Zhao, Qin-Hua Gu, Rong-Qing Chen, Zhuo Xu, Jing-Zhi Yan, Shan-Hui Wang, Su-Yi Liu, Zheng Chen, Wei L. Distinct trafficking and expression mechanisms underlie LTP and LTD of NMDA receptor-mediated synaptic responses. Hippocampus. vol 20. issue 5. 2010-08-10. PMID:19489005. |
in a study of nmdar-mediated synaptic responses in hippocampal schaffer-ca1 synapses whose ampa receptor (ampar) activity is totally blocked, we uncovered differences between the trafficking mechanisms that underlie the long-term potentiation (ltp) and long-term depression (ltd) that can be induced in these cells under these conditions. |
2010-08-10 |
2023-08-12 |
Not clear |
| Chiung-Chun Huang, Cheng-Che Lee, Kuei-Sen Hs. The role of insulin receptor signaling in synaptic plasticity and cognitive function. Chang Gung medical journal. vol 33. issue 2. 2010-08-06. PMID:20438663. |
insulin has also recently been shown to regulate the endocytosis of 3-hydroxy-5-methylisoxazole-4-propionic acid (ampa) receptors, which causes long-term depression (ltd) of excitatory synaptic transmission. |
2010-08-06 |
2023-08-12 |
Not clear |
| Ralf Scholz, Sven Berberich, Louisa Rathgeber, Alexander Kolleker, Georg Köhr, Hans-Christian Korna. AMPA receptor signaling through BRAG2 and Arf6 critical for long-term synaptic depression. Neuron. vol 66. issue 5. 2010-07-19. PMID:20547133. |
long-term depression (ltd) reflects a sustained reduction of the synaptic ampa receptor content based on targeted clathrin-mediated endocytosis. |
2010-07-19 |
2023-08-12 |
Not clear |
| Zheng Li, Jihoon Jo, Jie-Min Jia, Shih-Ching Lo, Daniel J Whitcomb, Song Jiao, Kwangwook Cho, Morgan Shen. Caspase-3 activation via mitochondria is required for long-term depression and AMPA receptor internalization. Cell. vol 141. issue 5. 2010-06-17. PMID:20510932. |
caspase-3 activation via mitochondria is required for long-term depression and ampa receptor internalization. |
2010-06-17 |
2023-08-12 |
mouse |
| Yun Wang, Jing Wu, Zhiguo Wu, Qing Lin, Yun Yue, Li Fan. Regulation of AMPA receptors in spinal nociception. Molecular pain. vol 6. 2010-06-10. PMID:20092646. |
the ampa receptors present a unique characteristic in the mechanisms of subunit regulation during ltp (long-term potentiation) and ltd (long-term depression), which are involved in the trafficking, altered composition and phosphorylation of ampa receptor subunits. |
2010-06-10 |
2023-08-12 |
Not clear |
| Takahiro Yaguchi, Tetsu Nagata, Tomoyuki Nishizak. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine improves cognitive decline by enhancing long-term depression. Behavioural brain research. vol 204. issue 1. 2009-12-01. PMID:19482045. |
1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (pophtcho) (1 microm) enhanced long-term depression (ltd), a synaptic plasticity relevant to learning and memory, in the ca1 region of rat hippocampal slices, where expression of the alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (ampa) receptor subunit glur1 on the plasma membrane was decreased. |
2009-12-01 |
2023-08-12 |
rat |
| Malik Khelfaoui, Alice Pavlowsky, Andrew D Powell, Pamela Valnegri, Kenneth W Cheong, Yann Blandin, Maria Passafaro, John G R Jefferys, Jamel Chelly, Pierre Billuar. Inhibition of RhoA pathway rescues the endocytosis defects in Oligophrenin1 mouse model of mental retardation. Human molecular genetics. vol 18. issue 14. 2009-09-14. PMID:19401298. |
indeed disruption of ophn1 in mice reduces the endocytosis of synaptic vesicles and the post-synaptic alpha-amino-3-hydroxy-5-methylisoazol-4-propionate (ampa) receptor internalization, resulting in almost a complete loss of long-term depression in the hippocampus. |
2009-09-14 |
2023-08-12 |
mouse |
| Shunmoogum A Patten, Declan W Al. PKCgamma-induced trafficking of AMPA receptors in embryonic zebrafish depends on NSF and PICK1. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 16. 2009-05-29. PMID:19366675. |
the trafficking of ampa receptors (rs) to and from synaptic membranes is a key component underlying synaptic plasticity mechanisms such as long-term potentiation (ltp) and long-term depression (ltd), and is likely important for synaptic development in embryonic organisms. |
2009-05-29 |
2023-08-12 |
zebrafish |
| Houman Khosravani, Yunfeng Zhang, Gerald W Zampon. Cellular prion protein null mice display normal AMPA receptor mediated long term depression. Prion. vol 2. issue 2. 2009-03-19. PMID:19098438. |
cellular prion protein null mice display normal ampa receptor mediated long term depression. |
2009-03-19 |
2023-08-12 |
mouse |
| Houman Khosravani, Yunfeng Zhang, Gerald W Zampon. Cellular prion protein null mice display normal AMPA receptor mediated long term depression. Prion. vol 2. issue 2. 2009-03-19. PMID:19098438. |
here we show that prp-null mice show a normal response to long-term depression stimuli requiring ampa receptor activity, thus further supporting our previous findings of a selective action on nmda receptors among ionotropic glutamate receptors. |
2009-03-19 |
2023-08-12 |
mouse |
| Samarjit Bhattacharyya, Virginie Biou, Weifeng Xu, Oliver Schlüter, Robert C Malenk. A critical role for PSD-95/AKAP interactions in endocytosis of synaptic AMPA receptors. Nature neuroscience. vol 12. issue 2. 2009-02-27. PMID:19169250. |
the endocytosis of ampa receptors (ampars) underlies several forms of synaptic plasticity, including nmda receptor (nmdar)-dependent long-term depression (ltd), but the molecular mechanisms responsible for this trafficking remain unknown. |
2009-02-27 |
2023-08-12 |
rat |
| Alejandra M Pacchioni, Joseph Vallone, Paul F Worley, Peter W Kaliva. Neuronal pentraxins modulate cocaine-induced neuroadaptations. The Journal of pharmacology and experimental therapeutics. vol 328. issue 1. 2009-02-03. PMID:18840757. |
narp and np1 enhance synaptogenesis and glutamate signaling by clustering ampa receptors, whereas npr contributes to removing ampa receptors during group i metabotropic glutamate receptor-dependent long-term depression. |
2009-02-03 |
2023-08-12 |
mouse |