All Relations between long term depression and hippocampus

Publication Sentence Publish Date Extraction Date Species
Naoya Atarashi, Misaki Morishita, Shinji Matsud. Activation of innate immune receptor TLR9 by mitochondrial DNA plays essential roles in the chemical long-term depression of hippocampal neurons. The Journal of biological chemistry. 2024-02-14. PMID:38354781. activation of innate immune receptor tlr9 by mitochondrial dna plays essential roles in the chemical long-term depression of hippocampal neurons. 2024-02-14 2024-02-17 Not clear
Liam T Ralph, John Georgiou, Graham L Collingridge, Patrick Tidbal. Sex-dependence of synaptic depression induced by activation of metabotropic glutamate receptors in rat hippocampus. Brain and neuroscience advances. vol 8. 2024-02-01. PMID:38298523. we studied dhpg-induced long-term depression at the schaffer collateral-commissural pathway in area ca1 of hippocampal slices prepared from three separate age groups of sprague dawley rats. 2024-02-01 2024-02-03 rat
Hayuma Otsuka, Sachie Sasaki-Hamada, Hitoshi Ishibashi, Jun-Ichiro Ok. Hippocampal acetylcholine receptor activation-dependent long-term depression in streptozotocin-induced diabetic rats. Neuroscience letters. 2024-01-22. PMID:38253285. hippocampal acetylcholine receptor activation-dependent long-term depression in streptozotocin-induced diabetic rats. 2024-01-22 2024-01-25 rat
Priyanka D Pinky, Jenna Bloemer, Warren D Smith, Yifeng Du, Ryan T Heslin, Sharay E Setti, Jeremiah C Pfitzer, Kawsar Chowdhury, Hao Hong, Subhrajit Bhattacharya, Muralikrishnan Dhanasekaran, Alexander Dityatev, Miranda N Reed, Vishnu Suppiramania. Prenatal Cannabinoid Exposure Elicits Memory Deficits Associated with Reduced PSA-NCAM Expression, Altered Glutamatergic Signaling, and Adaptations in Hippocampal Synaptic Plasticity. Cells. vol 12. issue 21. 2023-11-10. PMID:37947603. hippocampal-dependent memory deficits in adolescent pce animals were associated with decreased long-term potentiation (ltp) and enhanced long-term depression (ltd) at hippocampal schaffer collateral-ca1 synapses, as well as an imbalance between glun2a- and glun2b-mediated signaling. 2023-11-10 2023-11-20 rat
Marc Dahlmanns, Maria Jesus Valero-Aracama, Jana Katharina Dahlmanns, Fang Zheng, Christian Alzheime. Tonic activin signaling shapes cellular and synaptic properties of CA1 neurons mainly in dorsal hippocampus. iScience. vol 26. issue 10. 2023-10-13. PMID:37829200. using transgenic mice with a forebrain-specific disruption of activin receptor signaling, we identified the pronounced dorsal-ventral gradient of activin a as a major factor determining the distinct neurophysiologic signatures of dorsal and ventral hippocampus, ranging from pyramidal cell firing, tuning of frequency-dependent synaptic facilitation, to long-term potentiation (ltp), long-term depression (ltd), and de-potentiation. 2023-10-13 2023-10-15 mouse
Thu-Huong Hoang, Denise Manahan-Vaugha. Differentiated somatic gene expression is triggered in the dorsal hippocampus and the anterior retrosplenial cortex by hippocampal synaptic plasticity prompted by spatial content learning. Brain structure & function. 2023-09-10. PMID:37690045. spatial content learning promotes the expression of hippocampal synaptic plasticity, particularly long-term depression (ltd). 2023-09-10 2023-10-07 rat
Jill Rocchetti, Caroline Fasano, Gregory Dal-Bo, Elisa Guma, Salah El Mestikawy, Tak-Pan Wong, Gohar Fakhfouri, Bruno Giro. Persistent extrasynaptic hyperdopaminergia in the mouse hippocampus induces plasticity and recognition memory deficits reversed by the atypical antipsychotic sulpiride. PloS one. vol 18. issue 8. 2023-08-25. PMID:37624765. in vitro application of gbr on hippocampal slices abolished long-term depression (ltd) of fepsp in temporal ca1. 2023-08-25 2023-09-07 mouse
Luisa Di Menna, Rosamaria Orlando, Giovanna D'Errico, Roxana Paula Ginerete, Agata Machaczka, Carmela M Bonaccorso, Andrea Arena, Michela Spatuzza, Roberta Celli, Marika Alborghetti, Eleonora Ciocca, Anna Rita Zuena, Maria Rosaria Scioli, Valeria Bruno, Giuseppe Battaglia, Ferdinando Nicoletti, Maria Vincenza Catani. Blunted type-5 metabotropic glutamate receptor-mediated polyphosphoinositide hydrolysis in two mouse models of monogenic autism. Neuropharmacology. 2023-07-01. PMID:37392820. the involvement of the mglu5 receptors in the pathophysiology of several forms of monogenic autism has been supported by numerous studies following the seminal observation that mglu5 receptor-dependent long-term depression was enhanced in the hippocampus of mice modeling the fragile-x syndrome (fxs). 2023-07-01 2023-08-14 mouse
Price Obot, Galadu Subah, Antonia Schonwald, Jian Pan, Libor Velíšek, Jana Velíšková, Patric K Stanton, Eliana Sceme. Astrocyte and Neuronal Panx1 Support Long-Term Reference Memory in Mice. ASN neuro. vol 15. 2023-06-27. PMID:37365910. field potential recordings in hippocampal slices of panx1-null mice revealed an attenuation of both long-term potentiation (ltp) of synaptic strength and long-term depression (ltd) at schaffer collateral-ca1 synapses without alterations of basal synaptic transmission or pre-synaptic paired-pulse facilitation. 2023-06-27 2023-08-14 mouse
Suhel Parvez, Binu Ramachandran, Medha Kaushik, Heena Tabassum, Julietta U Fre. Long-term depression induction and maintenance across regions of the apical branch of CA1 dendrites. Hippocampus. 2023-05-31. PMID:37254828. well known as the center for learning and memory, hippocampus is the crucial brain region to study synaptic plasticity in the context of cellular fundamental mechanisms such as long-term depression (ltd) and long-term potentiation (ltp). 2023-05-31 2023-08-14 rat
Ela Mishra, Mahendra Kumar Thaku. Mitophagy: A promising therapeutic target for neuroprotection during aging and age-related diseases. British journal of pharmacology. 2023-02-15. PMID:36792062. besides the maintenance of brain homeostasis, hippocampal mitophagy also helps in synapse formation, axonal development, dopamine release, and long-term depression. 2023-02-15 2023-08-14 Not clear
Price Obot, Galadu Subah, Antonia Schonwald, Jian Pan, Libor Velíšek, Jana Velíšková, Patric K Stanton, Eliana Sceme. Astrocyte and neuronal Panx1 support long-term reference memory in mice. bioRxiv : the preprint server for biology. 2023-01-30. PMID:36711845. field potential recordings in hippocampal slices of panx1-null mice revealed an attenuation of both long-term potentiation (ltp) of synaptic strength and long-term depression (ltd) at schaffer collateral - ca1 synapses without alterations basal synaptic transmission or pre-synaptic paired-pulse facilitation. 2023-01-30 2023-08-14 mouse
Zhengtao Hu, Tomas Ondrejcak, Pengpeng Yu, Yangyang Zhang, Yin Yang, Igor Klyubin, Sean P Kennelly, Michael J Rowan, Neng-Wei H. Do tau-synaptic long-term depression interactions in the hippocampus play a pivotal role in the progression of Alzheimer's disease? Neural regeneration research. vol 18. issue 6. 2022-12-01. PMID:36453396. do tau-synaptic long-term depression interactions in the hippocampus play a pivotal role in the progression of alzheimer's disease? 2022-12-01 2023-08-14 Not clear
Zhengtao Hu, Tomas Ondrejcak, Pengpeng Yu, Yangyang Zhang, Yin Yang, Igor Klyubin, Sean P Kennelly, Michael J Rowan, Neng-Wei H. Do tau-synaptic long-term depression interactions in the hippocampus play a pivotal role in the progression of Alzheimer's disease? Neural regeneration research. vol 18. issue 6. 2022-12-01. PMID:36453396. conversely, certain forms of long-term depression at hippocampal glutamatergic synapses require endogenous tau, in particular, phosphorylation at residue ser396. 2022-12-01 2023-08-14 Not clear
Guoxiang Fang, Ying Wan. Hippocampal CB1 Receptor mediates antidepressant-like effect of Synthetic Cannabinoid-HU210 in Acute Despair Reaction model in mice. Neuroscience letters. 2022-11-13. PMID:36372093. pretreatment with am251, an inhibitor of cb1r or inhibition of long-term depression (ltd) at hippocampal ca3-ca1 synapses by tat-glur2 attenuated the antidepressant like action of hu-210. 2022-11-13 2023-08-14 mouse
Hardy Hagena, Denise Manahan-Vaugha. Role of mGlu5 in Persistent Forms of Hippocampal Synaptic Plasticity and the Encoding of Spatial Experience. Cells. vol 11. issue 21. 2022-11-11. PMID:36359749. studies in freely behaving rodents have revealed that mglu5 plays a pivotal role in the stabilisation of hippocampal long-term potentiation (ltp) and long-term depression (ltd) that are tightly associated with the acquisition and retention of knowledge about spatial experience. 2022-11-11 2023-08-14 Not clear
Débora Buendía, Tatiana Guncay, Macarena Oyanedel, Makarena Lemus, Alejandro Weinstein, Álvaro O Ardiles, José Marcos, Adriana Fernandes, Renato Zângaro, Pablo Muño. The Transcranial Light Therapy Improves Synaptic Plasticity in the Alzheimer's Disease Mouse Model. Brain sciences. vol 12. issue 10. 2022-10-27. PMID:36291206. sp, on the other hand, was evaluated using four electrophysiological parameters from the schaffer-ca1 collateral hippocampal synapses: excitatory field potentials (fepsp), paired pulse facilitation (ppf), long-term depression (ltd), and long-term potentiation (ltp). 2022-10-27 2023-08-14 mouse
Jiandong Sun, Yan Liu, Xiaoning Hao, Michel Baudry, Xiaoning B. Lack of UBE3A-Mediated Regulation of Synaptic SK2 Channels Contributes to Learning and Memory Impairment in the Female Mouse Model of Angelman Syndrome. Neural plasticity. vol 2022. 2022-10-14. PMID:36237484. like in male as mice, long-term potentiation (ltp) was significantly reduced while long-term depression (ltd) was enhanced at hippocampal ca3-ca1 synapses of female as mice, as compared to female wt mice. 2022-10-14 2023-08-14 mouse
Braulio Munoz, Brandon M Fritz, Fuqin Yin, Brady K Atwoo. HCN1 channels mediate mu opioid receptor long-term depression at insular cortex inputs to the dorsal striatum. The Journal of physiology. 2022-10-01. PMID:36181477. dorsal striatal cannabinoid long-term depression requires mtor signaling, similar to hippocampal cannabinoid long-term depression, but dorsal striatal mu opioid long-term depression does not require mtor signaling. 2022-10-01 2023-08-14 Not clear
Wei Sun, Yang Yang, Xiao Chen, Yazi Mei, Xiaoliang Li, Lei A. Prenatal cyanuric acid exposure disrupts cognitive flexibility and mGluR1-mediated hippocampal long-term depression in male rats. Toxicology letters. 2022-09-24. PMID:36152796. prenatal cyanuric acid exposure disrupts cognitive flexibility and mglur1-mediated hippocampal long-term depression in male rats. 2022-09-24 2023-08-14 rat