| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Norman. Towards a new model for cellular pathophysiology in affective disorder. Acta neuropsychiatrica. vol 12. issue 3. 2016-03-16. PMID:26975257. |
we tested the modulation of hippocampal long-term plasticity, a model for learning and memory, by 5-ht and found a selective impairment of long-term depression resulting in a positive modification of synaptic network properties. |
2016-03-16 |
2023-08-13 |
Not clear |
| Yosuke Takei, Yayoi S Kikkawa, Nafiseh Atapour, Takao K Hensch, Nobutaka Hirokaw. Defects in Synaptic Plasticity, Reduced NMDA-Receptor Transport, and Instability of Postsynaptic Density Proteins in Mice Lacking Microtubule-Associated Protein 1A. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 47. 2016-03-14. PMID:26609151. |
the mice exhibited learning disabilities, which correlated with decreased long-term potentiation and long-term depression in the hippocampal neurons, as well as a concomitant reduction in the extent of nr-dependent epscs. |
2016-03-14 |
2023-08-13 |
mouse |
| Jenny I Szu, Devin K Binde. The Role of Astrocytic Aquaporin-4 in Synaptic Plasticity and Learning and Memory. Frontiers in integrative neuroscience. vol 10. 2016-03-04. PMID:26941623. |
in this review, we explore the current literature on aqp4 and its influence on long term potentiation (ltp) and long term depression (ltd) in the hippocampus as well as the potential relationship between aqp4 and in learning and memory. |
2016-03-04 |
2023-08-13 |
mouse |
| Huili Han, Yan Peng, Zhifang Don. D-Serine rescues the deficits of hippocampal long-term potentiation and learning and memory induced by sodium fluoroacetate. Pharmacology, biochemistry, and behavior. vol 133. 2016-03-03. PMID:25843400. |
it is reported that impairing glial functions with sodium fluoroacetate (fac) impaired hippocampal long-term depression (ltd) and spatial memory retrieval. |
2016-03-03 |
2023-08-13 |
Not clear |
| Huili Han, Zhifang Dong, Yunfang Jia, Rongrong Mao, Qixin Zhou, Yuexiong Yang, Liping Wang, Lin Xu, Jun Ca. Opioid addiction and withdrawal differentially drive long-term depression of inhibitory synaptic transmission in the hippocampus. Scientific reports. vol 5. 2016-02-23. PMID:25942289. |
opioid addiction and withdrawal differentially drive long-term depression of inhibitory synaptic transmission in the hippocampus. |
2016-02-23 |
2023-08-13 |
Not clear |
| Huili Han, Zhifang Dong, Yunfang Jia, Rongrong Mao, Qixin Zhou, Yuexiong Yang, Liping Wang, Lin Xu, Jun Ca. Opioid addiction and withdrawal differentially drive long-term depression of inhibitory synaptic transmission in the hippocampus. Scientific reports. vol 5. 2016-02-23. PMID:25942289. |
here, we reported that a single in vivo morphine exposure (sm) did not affect inhibitory long-term depression (i-ltd) in the hippocampus, compared with saline control; while repeated morphine exposure (rm) abolished this i-ltd. interestingly, opioid withdrawal for 3-5 days after repeated (rmw), but not a single morphine exposure (smw), largely enhanced i-ltd. more importantly, the i-ltd in single morphine treatment is dependent on presynaptic mechanism since it can be blocked by am251, a selective cannabinoid receptor 1 antagonist. |
2016-02-23 |
2023-08-13 |
Not clear |
| Deng-Xin Zhang, Shan Jiang, Li-Na Yu, Feng-Jiang Zhang, Qing Zhuang, Min Ya. The effect of sevoflurane on the cognitive function of rats and its association with the inhibition of synaptic transmission. International journal of clinical and experimental medicine. vol 8. issue 11. 2016-02-17. PMID:26885010. |
to observe the effects of different concentrations of sevoflurane on synaptotagmin 1 (syt1) expression, synaptic long term depression (ltd), and paired pulse depression (ppd) in the rat hippocampus as well as to investigate the association between these effects and the cognitive function of rats. |
2016-02-17 |
2023-08-13 |
rat |
| Dave Jappy, Fliza Valiullina, Andreas Draguhn, Andrei Rozo. GABABR-Dependent Long-Term Depression at Hippocampal Synapses between CB1-Positive Interneurons and CA1 Pyramidal Cells. Frontiers in cellular neuroscience. vol 10. 2016-02-09. PMID:26858602. |
gababr-dependent long-term depression at hippocampal synapses between cb1-positive interneurons and ca1 pyramidal cells. |
2016-02-09 |
2023-08-13 |
Not clear |
| J Bohacek, M Farinelli, O Mirante, G Steiner, K Gapp, G Coiret, M Ebeling, G Durán-Pacheco, A L Iniguez, F Manuella, J-L Moreau, I M Mansu. Pathological brain plasticity and cognition in the offspring of males subjected to postnatal traumatic stress. Molecular psychiatry. vol 20. issue 5. 2016-01-19. PMID:25092246. |
long-term potentiation is abolished and long-term depression is enhanced in the hippocampus, and these defects are associated with impaired long-term memory in both the exposed fathers and their offspring. |
2016-01-19 |
2023-08-13 |
mouse |
| Shuxi Liu, Yue Wang, Paul F Worley, Mark P Mattson, Nicholas Gaian. The canonical Notch pathway effector RBP-J regulates neuronal plasticity and expression of GABA transporters in hippocampal networks. Hippocampus. vol 25. issue 5. 2016-01-13. PMID:25515406. |
here, we report that conditional disruption of rbp-j in the postnatal hippocampus leads to defects in long-term potentiation, long-term depression, and in learning and memory. |
2016-01-13 |
2023-08-13 |
Not clear |
| Jinzhong Jeremy Goh, Denise Manahan-Vaugha. Role of inhibitory autophosphorylation of calcium/calmodulin-dependent kinase II (αCAMKII) in persistent (>24 h) hippocampal LTP and in LTD facilitated by novel object-place learning and recognition in mice. Behavioural brain research. vol 285. 2015-12-14. PMID:24480420. |
persistent forms of synaptic plasticity in the hippocampus, such as long-term potentiation (ltp) and long-term depression (ltd) are particularly of interest, as evidence is accumulating that they are expressed as a consequence of, or at the very least in association with, hippocampus-dependent novel learning events. |
2015-12-14 |
2023-08-12 |
mouse |
| Neng-Wei Hu, Andrew J Nicoll, Dainan Zhang, Alexandra J Mably, Tiernan O'Malley, Silvia A Purro, Cassandra Terry, John Collinge, Dominic M Walsh, Michael J Rowa. mGlu5 receptors and cellular prion protein mediate amyloid-β-facilitated synaptic long-term depression in vivo. Nature communications. vol 5. 2015-12-14. PMID:24594908. |
here we describe how aβ facilitates nmdar-independent long-term depression of synaptic transmission in the hippocampus in vivo. |
2015-12-14 |
2023-08-12 |
Not clear |
| Jill Rocchetti, Elsa Isingrini, Gregory Dal Bo, Sara Sagheby, Aurore Menegaux, François Tronche, Daniel Levesque, Luc Moquin, Alain Gratton, Tak Pan Wong, Marcelo Rubinstein, Bruno Giro. Presynaptic D2 dopamine receptors control long-term depression expression and memory processes in the temporal hippocampus. Biological psychiatry. vol 77. issue 6. 2015-11-30. PMID:24742619. |
presynaptic d2 dopamine receptors control long-term depression expression and memory processes in the temporal hippocampus. |
2015-11-30 |
2023-08-13 |
Not clear |
| Argel Aguilar-Valles, Edna Matta-Camacho, Arkady Khoutorsky, Christos Gkogkas, Karim Nader, Jean-Claude Lacaille, Nahum Sonenber. Inhibition of Group I Metabotropic Glutamate Receptors Reverses Autistic-Like Phenotypes Caused by Deficiency of the Translation Repressor eIF4E Binding Protein 2. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 31. 2015-11-05. PMID:26245973. |
augmented hippocampal mglur-induced long-term depression (ltd; or chemically induced mglur-ltd) in eif4ebp2(-/-) mice was rescued by mglur1 or mglur5 antagonists. |
2015-11-05 |
2023-08-13 |
mouse |
| Eric S Sweet, Bernadette Saunier-Rebori, Zhenyu Yue, Robert D Blitze. The Parkinson's Disease-Associated Mutation LRRK2-G2019S Impairs Synaptic Plasticity in Mouse Hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 32. 2015-11-05. PMID:26269629. |
through electrophysiological analysis of the schaffer collateral-ca1 synapse in dorsal hippocampus, we find that overexpression of lrrk2-g2019s increases basal synaptic efficiency through a postsynaptic mechanism, and disrupts long-term depression. |
2015-11-05 |
2023-08-13 |
mouse |
| Robert Alan Mans, Brian A Warmus, Caroline C Smith, Lori L McMaho. An acetylcholinesterase inhibitor, eserine, induces long-term depression at CA3-CA1 synapses in the hippocampus of adult rats. Journal of neurophysiology. vol 112. issue 10. 2015-10-19. PMID:25143547. |
an acetylcholinesterase inhibitor, eserine, induces long-term depression at ca3-ca1 synapses in the hippocampus of adult rats. |
2015-10-19 |
2023-08-13 |
rat |
| Toshiyuki Mizui, Yasuyuki Ishikawa, Haruko Kumanogoh, Maria Lume, Tomoya Matsumoto, Tomoko Hara, Shigeto Yamawaki, Masami Takahashi, Sadao Shiosaka, Chiaki Itami, Koichi Uegaki, Mart Saarma, Masami Kojim. BDNF pro-peptide actions facilitate hippocampal LTD and are altered by the common BDNF polymorphism Val66Met. Proceedings of the National Academy of Sciences of the United States of America. vol 112. issue 23. 2015-09-25. PMID:26015580. |
interestingly, we found that the bdnf pro-peptide directly facilitates hippocampal long-term depression (ltd), requiring the activation of glun2b-containing nmda receptors and the pan-neurotrophin receptor p75(ntr). |
2015-09-25 |
2023-08-13 |
human |
| Zsuzsanna Callaerts-Vegh, Tariq Ahmed, Ben Vermaercke, Peter Marynen, Detlef Balschun, Guy Froyen, Rudi D'Hoog. Nxf7 deficiency impairs social exploration and spatio-cognitive abilities as well as hippocampal synaptic plasticity in mice. Frontiers in behavioral neuroscience. vol 9. 2015-07-28. PMID:26217206. |
this distinct neurocognitive phenotype was accompanied by impaired hippocampal long-term potentiation (ltp), while long-term depression (ltd) was not affected by nxf7 deficiency. |
2015-07-28 |
2023-08-13 |
mouse |
| Taulant Bacaj, Mohiuddin Ahmad, Sandra Jurado, Robert C Malenka, Thomas C Südho. Synaptic Function of Rab11Fip5: Selective Requirement for Hippocampal Long-Term Depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 19. 2015-07-27. PMID:25972173. |
synaptic function of rab11fip5: selective requirement for hippocampal long-term depression. |
2015-07-27 |
2023-08-13 |
mouse |
| Valentina Wiescholleck, Denise Manahan-Vaugha. Antagonism of D1/D5 receptors prevents long-term depression (LTD) and learning-facilitated LTD at the perforant path-dentate gyrus synapse in freely behaving rats. Hippocampus. vol 24. issue 12. 2015-07-22. PMID:25112177. |
hippocampal synaptic plasticity, in the form of long-term potentiation (ltp) and long-term depression (ltd), enables spatial memory formation, whereby ltp and ltd are likely to contribute different elements to the resulting spatial representation. |
2015-07-22 |
2023-08-13 |
rat |