| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Beatrice Pöschel, Denise Manahan-Vaugha. Persistent (>24h) long-term depression in the dentate gyrus of freely moving rats is not dependent on activation of NMDA receptors, L-type voltage-gated calcium channels or protein synthesis. Neuropharmacology. vol 52. issue 1. 2007-03-02. PMID:16899259. |
hippocampal long-term depression (ltd) comprises a persistent reduction of synaptic strength that is typically induced by low frequency stimulation (lfs). |
2007-03-02 |
2023-08-12 |
rat |
| Yue Wang, Jennifer Mackes, Stephen Chan, Norman J Haughey, Zhihong Guo, Xin Ouyang, Katsutoshi Furukawa, Donald K Ingram, Mark P Mattso. Impaired long-term depression in P2X3 deficient mice is not associated with a spatial learning deficit. Journal of neurochemistry. vol 99. issue 5. 2007-01-23. PMID:17074061. |
despite the deficit in hippocampal long-term depression, p2x3ko mice performed normally in water maze tests of spatial learning, suggesting that long-term depression is not critical for this type of hippocampus-dependent learning and memory. |
2007-01-23 |
2023-08-12 |
mouse |
| Aya Ito-Ishida, Wataru Kakegawa, Michisuke Yuzak. ERK1/2 but not p38 MAP kinase is essential for the long-term depression in mouse cerebellar slices. The European journal of neuroscience. vol 24. issue 6. 2007-01-05. PMID:17004925. |
in the hippocampus, three different mapk subfamilies, extracellular signal-regulated kinase 1/2 (erk1/2), p38 mapk and c-jun nh2-terminal protein kinase (jnk), selectively regulate activity-dependent glutamate receptor trafficking during long-term potentiation (ltp), long-term depression (ltd), and depotentiation after ltp, respectively. |
2007-01-05 |
2023-08-12 |
mouse |
| Meina Wang, Ya Yang, Zhifang Dong, Jun Cao, Lin X. NR2B-containing N-methyl-D-aspartate subtype glutamate receptors regulate the acute stress effect on hippocampal long-term potentiation/long-term depression in vivo. Neuroreport. vol 17. issue 12. 2006-10-18. PMID:16951582. |
behavioral stress facilitates long-term depression but impairs long-term potentiation in the hippocampus. |
2006-10-18 |
2023-08-12 |
rat |
| Meina Wang, Ya Yang, Zhifang Dong, Jun Cao, Lin X. NR2B-containing N-methyl-D-aspartate subtype glutamate receptors regulate the acute stress effect on hippocampal long-term potentiation/long-term depression in vivo. Neuroreport. vol 17. issue 12. 2006-10-18. PMID:16951582. |
recent evidence in vitro demonstrates that the nr2b-containing n-methyl-d-aspartate subtype glutamate receptor antagonist ro25-6981 prevents the behavioral stress-facilitated hippocampal long-term depression. |
2006-10-18 |
2023-08-12 |
rat |
| Meina Wang, Ya Yang, Zhifang Dong, Jun Cao, Lin X. NR2B-containing N-methyl-D-aspartate subtype glutamate receptors regulate the acute stress effect on hippocampal long-term potentiation/long-term depression in vivo. Neuroreport. vol 17. issue 12. 2006-10-18. PMID:16951582. |
it is, however, unknown whether ro25-6981 influences hippocampal long-term depression and long-term potentiation induction in vivo under stressful condition. |
2006-10-18 |
2023-08-12 |
rat |
| Meina Wang, Ya Yang, Zhifang Dong, Jun Cao, Lin X. NR2B-containing N-methyl-D-aspartate subtype glutamate receptors regulate the acute stress effect on hippocampal long-term potentiation/long-term depression in vivo. Neuroreport. vol 17. issue 12. 2006-10-18. PMID:16951582. |
here, we found that infusion of ro25-6981 (2.3 microg in 6 microl, intracerebroventricular for 10 min) 30 min before low-frequency stimulation prevented the facilitation of hippocampal long-term depression by acute stress in anesthetized adult rats. |
2006-10-18 |
2023-08-12 |
rat |
| Meina Wang, Ya Yang, Zhifang Dong, Jun Cao, Lin X. NR2B-containing N-methyl-D-aspartate subtype glutamate receptors regulate the acute stress effect on hippocampal long-term potentiation/long-term depression in vivo. Neuroreport. vol 17. issue 12. 2006-10-18. PMID:16951582. |
these results suggest that the nr2b-containing n-methyl-d-aspartate subtype glutamate receptors are crucial for the effects of behavioral stress on hippocampal long-term depression and long-term potentiation in vivo. |
2006-10-18 |
2023-08-12 |
rat |
| I G Sil'ki. [What mechanisms underlie involvement of different NMDA receptor subunits in the induction of hippocampal long-term potentiation and long-term depression?]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 56. issue 3. 2006-10-13. PMID:16869279. |
[what mechanisms underlie involvement of different nmda receptor subunits in the induction of hippocampal long-term potentiation and long-term depression?]. |
2006-10-13 |
2023-08-12 |
Not clear |
| L Lecourtier, O Deschaux, C Arnaud, A Chessel, P H Kelly, R Garci. Habenula lesions alter synaptic plasticity within the fimbria-accumbens pathway in the rat. Neuroscience. vol 141. issue 2. 2006-10-04. PMID:16716523. |
as the habenular nuclei have been shown to influence the release of many neurotransmitters, both in the hippocampus and the nucleus accumbens, we examined in this study the effects of bilateral habenula lesions on the plasticity of the fimbria-nucleus accumbens pathway, by means of the long-term depression phenomenon in freely moving rats. |
2006-10-04 |
2023-08-12 |
rat |
| Lenora J Volk, Christine A Daly, Kimberly M Hube. Differential roles for group 1 mGluR subtypes in induction and expression of chemically induced hippocampal long-term depression. Journal of neurophysiology. vol 95. issue 4. 2006-09-25. PMID:16421200. |
differential roles for group 1 mglur subtypes in induction and expression of chemically induced hippocampal long-term depression. |
2006-09-25 |
2023-08-12 |
mouse |
| P V Nguye. Comparative plasticity of brain synapses in inbred mouse strains. The Journal of experimental biology. vol 209. issue Pt 12. 2006-08-16. PMID:16731805. |
comparative electrophysiological data obtained from several inbred mouse strains are reviewed here to highlight the following key notions: (1) synaptic plasticity is influenced by the genetic backgrounds of inbred mice; (2) the plasticity of hippocampal synapses in inbred mice is ;tuned' to particular temporal patterns of activity; (3) long-term potentiation, but not long-term depression, is a cellular correlate of behavioural memory performance in some strains; (4) synaptic phenotyping of inbred mouse strains can identify cellular models of memory impairment that can be used to elucidate mechanisms that may cause specific memory deficits. |
2006-08-16 |
2023-08-12 |
mouse |
| Neal Lemon, Denise Manahan-Vaugha. Dopamine D1/D5 receptors gate the acquisition of novel information through hippocampal long-term potentiation and long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 29. 2006-08-14. PMID:16855100. |
dopamine d1/d5 receptors gate the acquisition of novel information through hippocampal long-term potentiation and long-term depression. |
2006-08-14 |
2023-08-12 |
rat |
| Neal Lemon, Denise Manahan-Vaugha. Dopamine D1/D5 receptors gate the acquisition of novel information through hippocampal long-term potentiation and long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 29. 2006-08-14. PMID:16855100. |
hippocampal synaptic plasticity, in the form of long-term potentiation (ltp) and long-term depression (ltd), has been implicated in both spatial memory formation as well as novelty acquisition. |
2006-08-14 |
2023-08-12 |
rat |
| Wei Xiong, Ljubomir Z Kojic, Lanjing Zhang, Shiv S Prasad, Robert Douglas, Yutian Wang, Max S Cynade. Anisomycin activates p38 MAP kinase to induce LTD in mouse primary visual cortex. Brain research. vol 1085. issue 1. 2006-08-10. PMID:16581040. |
it has been used to block the late phase of long-term potentiation (ltp) and long-term depression (ltd) in hippocampus. |
2006-08-10 |
2023-08-12 |
mouse |
| Yukitoshi Izumi, Yves P Auberson, Charles F Zorumsk. Zinc modulates bidirectional hippocampal plasticity by effects on NMDA receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 27. 2006-07-25. PMID:16822975. |
in the ca1 region of rat hippocampal slices, we observed that low micromolar concentrations of zinc depress nmdar synaptic responses by 40-50% and inhibit long-term depression (ltd) but not long-term potentiation (ltp). |
2006-07-25 |
2023-08-12 |
rat |
| Lisa Bjartmar, Andrew D Huberman, Erik M Ullian, René C Rentería, Xiaoqin Liu, Weifeng Xu, Jennifer Prezioso, Michael W Susman, David Stellwagen, Caleb C Stokes, Richard Cho, Paul Worley, Robert C Malenka, Sherry Ball, Neal S Peachey, David Copenhagen, Barbara Chapman, Masaru Nakamoto, Ben A Barres, Mark S Peri. Neuronal pentraxins mediate synaptic refinement in the developing visual system. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 23. 2006-07-07. PMID:16763034. |
other developmental processes, such as pathfinding of rgcs at the optic chiasm and hippocampal long-term potentiation and long-term depression, appeared normal in np-deficient mice. |
2006-07-07 |
2023-08-12 |
mouse |
| Elena D Nosyreva, Kimberly M Hube. Metabotropic receptor-dependent long-term depression persists in the absence of protein synthesis in the mouse model of fragile X syndrome. Journal of neurophysiology. vol 95. issue 5. 2006-06-28. PMID:16452252. |
metabotropic glutamate receptor-dependent long-term depression (mglur-ltd) in hippocampal area ca1 is a form of synaptic plasticity that relies on dendritic protein synthesis. |
2006-06-28 |
2023-08-12 |
mouse |
| Jing Qian, Jeffrey L Noebel. Exocytosis of vesicular zinc reveals persistent depression of neurotransmitter release during metabotropic glutamate receptor long-term depression at the hippocampal CA3-CA1 synapse. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 22. 2006-06-23. PMID:16738253. |
exocytosis of vesicular zinc reveals persistent depression of neurotransmitter release during metabotropic glutamate receptor long-term depression at the hippocampal ca3-ca1 synapse. |
2006-06-23 |
2023-08-12 |
Not clear |
| Jing Qian, Jeffrey L Noebel. Exocytosis of vesicular zinc reveals persistent depression of neurotransmitter release during metabotropic glutamate receptor long-term depression at the hippocampal CA3-CA1 synapse. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 22. 2006-06-23. PMID:16738253. |
a long-standing controversy in hippocampal synaptic plasticity involves the site of long-term depression (ltd) at these synapses. |
2006-06-23 |
2023-08-12 |
Not clear |