| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Joana Gonçalves-Ribeiro, Carolina Campos Pina, Ana Maria Sebastião, Sandra Henriques Va. Glutamate Transporters in Hippocampal LTD/LTP: Not Just Prevention of Excitotoxicity. Frontiers in cellular neuroscience. vol 13. 2020-09-29. PMID:31447647. |
in this review, we will focus on the role of the increase in glutamate uptake that occurs during long-term potentiation (ltp) in the hippocampus, as well as on the impairment of long-term depression (ltd) under the same conditions. |
2020-09-29 |
2023-08-13 |
Not clear |
| Tiffany J Petrisko, Jenna Bloemer, Priyanka D Pinky, Sriraja Srinivas, Ryan T Heslin, Yifeng Du, Sharay E Setti, Hao Hong, Vishnu Suppiramaniam, Gregory W Konat, Miranda N Ree. Neuronal CXCL10/CXCR3 Axis Mediates the Induction of Cerebral Hyperexcitability by Peripheral Viral Challenge. Frontiers in neuroscience. vol 14. 2020-09-28. PMID:32265633. |
the pic-mediated abolishment of hippocampal long-term depression (ltd) was also restored after administration of amg487. |
2020-09-28 |
2023-08-13 |
mouse |
| Soledad Domínguez, Christophe Clément Rey, Ludivine Therreau, Aurélien Fanton, Dominique Massotte, Laure Verret, Rebecca Ann Piskorowski, Vivien Chevaleyr. Maturation of PNN and ErbB4 Signaling in Area CA2 during Adolescence Underlies the Emergence of PV Interneuron Plasticity and Social Memory. Cell reports. vol 29. issue 5. 2020-09-25. PMID:31665627. |
we find that a long-term depression of inhibitory transmission (iltd) from parvalbumin-expressing (pv+) interneurons in the hippocampal area cornu ammonis 2 (ca2) is absent in young mice but emerges at the end of adolescence. |
2020-09-25 |
2023-08-13 |
mouse |
| Rafael Falcón-Moya, Mikel Pérez-Rodríguez, José Prius-Mengual, Yuniesky Andrade-Talavera, Luis E Arroyo-García, Rocío Pérez-Artés, Pedro Mateos-Aparicio, Sónia Guerra-Gomes, João Filipe Oliveira, Gonzalo Flores, Antonio Rodríguez-Moren. Astrocyte-mediated switch in spike timing-dependent plasticity during hippocampal development. Nature communications. vol 11. issue 1. 2020-09-21. PMID:32873805. |
presynaptic spike timing-dependent long-term depression (t-ltd) at hippocampal ca3-ca1 synapses is evident until the 3 |
2020-09-21 |
2023-08-13 |
Not clear |
| Adrián Martín-Segura, Tariq Ahmed, Álvaro Casadomé-Perales, Irene Palomares-Perez, Ernest Palomer, Axelle Kerstens, Sebastian Munck, Detlef Balschun, Carlos G Dott. Age-associated cholesterol reduction triggers brain insulin resistance by facilitating ligand-independent receptor activation and pathway desensitization. Aging cell. vol 18. issue 3. 2020-09-14. PMID:30884121. |
using long-term depression (ltd) induced by application of insulin to hippocampal slices as a read-out, we found that the decline in insulin function during aging could be monitored as a progressive impairment of insulin-ltd. |
2020-09-14 |
2023-08-13 |
mouse |
| Wangyong Shin, Kyungdeok Kim, Benjamin Serraz, Yi Sul Cho, Doyoun Kim, Muwon Kang, Eun-Jae Lee, Hyejin Lee, Yong Chul Bae, Pierre Paoletti, Eunjoon Ki. Early correction of synaptic long-term depression improves abnormal anxiety-like behavior in adult GluN2B-C456Y-mutant mice. PLoS biology. vol 18. issue 4. 2020-07-27. PMID:32353004. |
in grin2b+/c456y mice, glun2b protein levels were strongly reduced in association with decreased hippocampal nmdar currents and nmdar-dependent long-term depression (ltd) but unaltered long-term potentiation, indicative of mutation-induced protein degradation and ltd sensitivity. |
2020-07-27 |
2023-08-13 |
mouse |
| Thomas Maurin, Francesca Melancia, Marielle Jarjat, Liliana Castro, Lara Costa, Sébastien Delhaye, Anouar Khayachi, Sara Castagnola, Elia Mota, Audrey Di Giorgio, Michela Servadio, Malgorzata Drozd, Gwénola Poupon, Sara Schiavi, Lara Sardone, Stéphane Azoulay, Lucia Ciranna, Stéphane Martin, Pierre Vincent, Viviana Trezza, Barbara Bardon. Involvement of Phosphodiesterase 2A Activity in the Pathophysiology of Fragile X Syndrome. Cerebral cortex (New York, N.Y. : 1991). vol 29. issue 8. 2020-07-15. PMID:30137253. |
here, we pharmacologically inhibited pde2a in fmr1-ko mice and observed a rescue both of the maturity of dendritic spines and of the exaggerated hippocampal mglur-dependent long-term depression. |
2020-07-15 |
2023-08-13 |
mouse |
| Mikel Pérez-Rodríguez, Luis E Arroyo-García, José Prius-Mengual, Yuniesky Andrade-Talavera, José A Armengol, Eva M Pérez-Villegas, Paloma Duque-Feria, Gonzalo Flores, Antonio Rodríguez-Moren. Adenosine Receptor-Mediated Developmental Loss of Spike Timing-Dependent Depression in the Hippocampus. Cerebral cortex (New York, N.Y. : 1991). vol 29. issue 8. 2020-07-15. PMID:30169759. |
presynaptic spike timing-dependent long-term depression (t-ltd) exists in the hippocampus, which depends on the activation of nmdars and that probably fulfills a role in synaptic refinement. |
2020-07-15 |
2023-08-13 |
mouse |
| Spencer K Cooke, Jacob Russin, Kristen Moulton, Jeffrey Nadel, Inna Loutaev, Qinhua Gu, Zheng Li, Carolyn Beebe Smit. Effects of the presence and absence of amino acids on translation, signaling, and long-term depression in hippocampal slices from Fmr1 knockout mice. Journal of neurochemistry. vol 151. issue 6. 2020-06-11. PMID:31539452. |
effects of the presence and absence of amino acids on translation, signaling, and long-term depression in hippocampal slices from fmr1 knockout mice. |
2020-06-11 |
2023-08-13 |
mouse |
| Kevin Lee, Yukti Vyas, Craig C Garner, Johanna M Montgomer. Autism-associated Shank3 mutations alter mGluR expression and mGluR-dependent but not NMDA receptor-dependent long-term depression. Synapse (New York, N.Y.). vol 73. issue 8. 2020-04-30. PMID:30868621. |
we also induced mglur-dependent synaptic plasticity (r,s-3,5-dihydroxyphenylglycine [dhpg]-induced long-term depression [ltd]) as well as n-methyl-d-aspartate receptor (nmdar)-dependent ltd. asd-associated mutations in shank3 differentially interfered with the ability of cultured hippocampal neurons to express mglur5 and mglur1 at synapses. |
2020-04-30 |
2023-08-13 |
Not clear |
| Lei An, Jia Li, Le Luo, Peidong Huang, Peidong Liu, Chunzhi Tang, Wei Su. Prenatal melamine exposure impairs cognitive flexibility and hippocampal synaptic plasticity in adolescent and adult female rats. Pharmacology, biochemistry, and behavior. vol 186. 2020-04-02. PMID:31518600. |
long-term potentiation (ltp) and long-term depression (ltd) were recorded from the hippocampal schaffer collaterals to the ca1 area. |
2020-04-02 |
2023-08-13 |
rat |
| Lucia Privitera, Ellen L Hogg, Matthias Gaestel, Mark J Wall, Sonia A L Corrê. The MK2 cascade regulates mGluR-dependent synaptic plasticity and reversal learning. Neuropharmacology. vol 155. 2020-02-28. PMID:31129151. |
here we demonstrate that the p38 mapk/mapk-activated protein kinase 2 (mk2) cascade is required to maintain the precise tuning of long-term potentiation and long-term depression at ca1 synapses of the hippocampus which is correlated with efficient reversal learning. |
2020-02-28 |
2023-08-13 |
mouse |
| Iryna Hlushchenko, Pirta Hotulaine. Chemical LTD, but not LTP, induces transient accumulation of gelsolin in dendritic spines. Biological chemistry. vol 400. issue 9. 2020-02-17. PMID:31280237. |
here, we tested gelsolin's response to the induction of chemical long-term potentiation (cltp) or long-term depression (cltd) in cultured rat hippocampal neurons. |
2020-02-17 |
2023-08-13 |
rat |
| Xin Wu, Dong-Hui Wang, Ning-Ning Sun, Shao-Hua Su, Song-Jiang Zhang, Jian-Feng Ga. [Effects of different concentrations of calcitonin gene-related peptide on long-term depression of hippocampus in mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 71. issue 6. 2020-01-15. PMID:31879739. |
[effects of different concentrations of calcitonin gene-related peptide on long-term depression of hippocampus in mice]. |
2020-01-15 |
2023-08-13 |
mouse |
| Xin Wu, Dong-Hui Wang, Ning-Ning Sun, Shao-Hua Su, Song-Jiang Zhang, Jian-Feng Ga. [Effects of different concentrations of calcitonin gene-related peptide on long-term depression of hippocampus in mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 71. issue 6. 2020-01-15. PMID:31879739. |
the purpose of this study was to explore the effects of calcitonin gene-related peptide (cgrp) on the long-term depression (ltd) of hippocampus in mice. |
2020-01-15 |
2023-08-13 |
mouse |
| Marwa Yousef, Ercan Babür, Sumeyra Delibaş, Burak Tan, Ayşenur Çimen, Nurcan Dursun, Cem Süe. Adult-Onset Hypothyroidism Alters the Metaplastic Properties of Dentate Granule Cells by Decreasing Akt Phosphorylation. Journal of molecular neuroscience : MN. vol 68. issue 4. 2019-12-10. PMID:31069661. |
the expression of homosynaptic long-term depression (ltd) governs the subsequent induction of long-term potentiation (ltp) at hippocampal synapses. |
2019-12-10 |
2023-08-13 |
rat |
| P.-W. Gean, F.-C. Chang, P.-L. Yi, J.-H. Lin, J.-J. Tsa. Activation of Metabotropic Glutamate Receptors in Conjunction with Postsynaptic Depolarization Triggers a Long-Term Depression of the N-Methyl-D-Aspartate Receptor-Mediated Synaptic Potential in the Rat Hippocampus. Journal of biomedical science. vol 2. issue 2. 2019-11-20. PMID:11725053. |
activation of metabotropic glutamate receptors in conjunction with postsynaptic depolarization triggers a long-term depression of the n-methyl-d-aspartate receptor-mediated synaptic potential in the rat hippocampus. |
2019-11-20 |
2023-08-12 |
human |
| Pedro Cisternas, Paulina Salazar, Felipe G Serrano, Carla Montecinos-Oliva, Sebastián B Arredondo, Lorena Varela-Nallar, Salesa Barja, Carlos P Vio, Fernando Gomez-Pinilla, Nibaldo C Inestros. Fructose consumption reduces hippocampal synaptic plasticity underlying cognitive performance. Biochimica et biophysica acta. vol 1852. issue 11. 2019-11-20. PMID:26300486. |
there was a dramatic deterioration in the capacity of the hippocampus to sustain synaptic plasticity in the forms of long-term potentiation (ltp) and long-term depression (ltd). |
2019-11-20 |
2023-08-13 |
mouse |
| Jirapas Sripetchwandee, Hiranya Pintana, Piangkwan Sa-Nguanmoo, Chiraphat Boonnag, Wasana Pratchayasakul, Nipon Chattipakorn, Siriporn C Chattipakor. Comparative effects of sex hormone deprivation on the brain of insulin-resistant rats. The Journal of endocrinology. 2019-11-20. PMID:30689543. |
at the end of the experiments, rats were decapitated and their brains were collected to determine brain mitochondrial function, brain oxidative stress, hippocampal plasticity, insulin-induced long-term depression, dendritic spine density, and cognition. |
2019-11-20 |
2023-08-13 |
rat |
| Jirapas Sripetchwandee, Hiranya Pintana, Piangkwan Sa-Nguanmoo, Chiraphat Boonnag, Wasana Pratchayasakul, Nipon Chattipakorn, Siriporn C Chattipakor. Comparative effects of sex hormone deprivation on the brain of insulin-resistant rats. The Journal of endocrinology. 2019-11-20. PMID:30689543. |
we found that male and female rats fed a high-fat diet developed obese-insulin resistance by week 8 and brain defects via elevated brain oxidative stress, brain mitochondrial dysfunction, impaired insulin-induced long-term depression, hippocampal dysplasticity, reduced dendritic spine density, and cognitive decline by week 12. |
2019-11-20 |
2023-08-13 |
rat |