Patricia Soriano Roque, Carolina Thörn Perez, Mehdi Hooshmandi, Calvin Wong, Mohammad Javad Eslamizade, Shilan Heshmati, Nicole Brown, Vijendra Sharma, Kevin C Lister, Vanessa Magalie Goyon, Laura E Neagu-Lund, Cathy Shen, Nicolas Daccache, Hiroaki Sato, Tamaki Sato, Jeffrey S Mogil, Karim Nader, Christos G Gkogkas, Mihaela D Iordanova, Masha Prager-Khoutorsky, Heidi M McBride, Jean-Claude Lacaille, Linda Wykes, Thomas Schricker, Arkady Khoutorsk. Parvalbumin interneuron loss mediates repeated anesthesia-induced memory deficits in mice. The Journal of clinical investigation. 2022-11-17. PMID:36394958. |
preventing the loss of parvalbumin neurons by deleting a pro-apoptotic protein mapl (mitochondrial anchored protein ligase) selectively in parvalbumin neurons rescued anesthesia-induced deficits in pyramidal cell inhibition, and hippocampus-dependent long-term memory. |
2022-11-17 |
2023-08-14 |
mouse |