| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jodi M Gilman, Max T Curran, Vanessa Calderon, Randi M Schuster, A Eden Evin. Altered Neural Processing to Social Exclusion in Young Adult Marijuana Users. Biological psychiatry. Cognitive neuroscience and neuroimaging. vol 1. issue 2. 2019-11-20. PMID:26977454. |
controls, but not marijuana users, demonstrated significant activation in the insula, a region associated with negative emotion, when being excluded from the game. |
2019-11-20 |
2023-08-13 |
human |
| Travis M Moschak, Xuefei Wang, Regina M Carell. A Neuronal Ensemble in the Rostral Agranular Insula Tracks Cocaine-Induced Devaluation of Natural Reward and Predicts Cocaine Seeking. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 38. issue 39. 2019-10-21. PMID:30126972. |
one brain region implicated in those processes is the rostral agranular insular cortex (raic), although precisely how this region encodes negative affect associated with drug seeking is unknown. |
2019-10-21 |
2023-08-13 |
rat |
| Robin Shao, Way K W Lau, Mei-Kei Leung, Tatia M C Le. Subgenual anterior cingulate-insula resting-state connectivity as a neural correlate to trait and state stress resilience. Brain and cognition. vol 124. 2019-02-11. PMID:29758439. |
accumulating evidence indicates important roles of the subgenual anterior cingulate cortex and rostral limbic regions such as the anterior insula, in regulating stress-related affective responses and negative affect states in general. |
2019-02-11 |
2023-08-13 |
human |
| Robin Shao, Way K W Lau, Mei-Kei Leung, Tatia M C Le. Subgenual anterior cingulate-insula resting-state connectivity as a neural correlate to trait and state stress resilience. Brain and cognition. vol 124. 2019-02-11. PMID:29758439. |
we found that while the low-resilience group displayed higher trait negative affect and perceived greater task-related stress, only the high-resilience group showed increase of negative affect, along with greater decrease of left subgenual anterior cingulate-right anterior insula connectivity, following stress induction. |
2019-02-11 |
2023-08-13 |
human |
| Ya Zheng, Qi Li, Moqian Tian, Weizhi Nan, Guochun Yang, Jin Liang, Xun Li. Deficits in voluntary pursuit and inhibition of risk taking in sensation seeking. Human brain mapping. vol 38. issue 12. 2018-06-19. PMID:28885754. |
importantly, during the voluntary inhibition of risk taking, hss relative to lss showed greater fmri responses in brain areas implicated in cognitive control (the bilateral anterior cingulate cortex) and negative emotion (the right anterior insula). |
2018-06-19 |
2023-08-13 |
Not clear |
| Fang Wang, Xiaolong Jing, Jingyu Yang, Huan Wang, Rongwu Xiang, Wenyan Han, Xinxin Liu, Chunfu W. The role of the insular cortex in naloxone-induced conditioned place aversion in morphine-dependent mice. Physiological research. vol 65. issue 4. 2017-04-03. PMID:26988162. |
since the insular cortex is a key brain structure involved in the modulation of negative emotions, we investigated whether the integrity of the insular cortex was important for motivational aversion associated with morphine withdrawal as well as whether this kind of negative emotion induced neuroadaptation in the insular cortex. |
2017-04-03 |
2023-08-13 |
mouse |
| Costanza Papagno, Alberto Pisoni, Giulia Mattavelli, Alessandra Casarotti, Alessandro Comi, Francesca Fumagalli, Mirta Vernice, Enrica Fava, Marco Riva, Lorenzo Bell. Specific disgust processing in the left insula: New evidence from direct electrical stimulation. Neuropsychologia. vol 84. 2016-12-16. PMID:26836143. |
therefore, upon these intra-operative evidences, we argue for a selective role of the left insula in disgust recognition, although a (non significant) decrease in the recognition of other negative emotions was found. |
2016-12-16 |
2023-08-13 |
Not clear |
| Trevor Steward, Maria Picó-Pérez, Fernanda Mata, Ignacio Martínez-Zalacaín, Marta Cano, Oren Contreras-Rodríguez, Fernando Fernández-Aranda, Murat Yucel, Carles Soriano-Mas, Antonio Verdejo-Garcí. Emotion Regulation and Excess Weight: Impaired Affective Processing Characterized by Dysfunctional Insula Activation and Connectivity. PloS one. vol 11. issue 3. 2016-08-02. PMID:27003840. |
when instructed to regulate negative emotions by means of cognitive reappraisal, participants with excess weight displayed persistently heightened activation in the right anterior insula. |
2016-08-02 |
2023-08-13 |
human |
| Trevor Steward, Maria Picó-Pérez, Fernanda Mata, Ignacio Martínez-Zalacaín, Marta Cano, Oren Contreras-Rodríguez, Fernando Fernández-Aranda, Murat Yucel, Carles Soriano-Mas, Antonio Verdejo-Garcí. Emotion Regulation and Excess Weight: Impaired Affective Processing Characterized by Dysfunctional Insula Activation and Connectivity. PloS one. vol 11. issue 3. 2016-08-02. PMID:27003840. |
decreased responsivity was also found in right anterior insula, the orbitofrontal cortex and cerebellum during negative emotion experience in participants with excess weight. |
2016-08-02 |
2023-08-13 |
human |
| Trevor Steward, Maria Picó-Pérez, Fernanda Mata, Ignacio Martínez-Zalacaín, Marta Cano, Oren Contreras-Rodríguez, Fernando Fernández-Aranda, Murat Yucel, Carles Soriano-Mas, Antonio Verdejo-Garcí. Emotion Regulation and Excess Weight: Impaired Affective Processing Characterized by Dysfunctional Insula Activation and Connectivity. PloS one. vol 11. issue 3. 2016-08-02. PMID:27003840. |
our findings support contentions that excess weight is linked to an abnormal pattern of neural activation and connectivity during the experience and regulation of negative emotions, with the insula playing a key role in these alterations. |
2016-08-02 |
2023-08-13 |
human |
| Wan-Ling Tseng, Laura A Thomas, Elizabeth Harkins, Daniel S Pine, Ellen Leibenluft, Melissa A Brotma. Neural correlates of masked and unmasked face emotion processing in youth with severe mood dysregulation. Social cognitive and affective neuroscience. vol 11. issue 1. 2016-08-01. PMID:26137973. |
insula, phg, superior temporal gyrus and thalamus) manifests as hyper-sensitivity toward negative emotions and hypo-sensitivity toward positive emotions may be important in the etiology and maintenance of irritability, aggression and depressive symptoms in smd. |
2016-08-01 |
2023-08-13 |
human |
| Yu-Chu Yeh, Chung-Wei Lin, Wei-Chin Hsu, Wen-Jui Kuo, Yu-Chen Cha. Associated and dissociated neural substrates of aesthetic judgment and aesthetic emotion during the appreciation of everyday designed products. Neuropsychologia. vol 73. 2016-04-14. PMID:25998491. |
the study identified the following main findings: (a) normative beauty and subjective beauty both involved the left anterior cingulate cortex (acc); (b) subjective beauty and positive emotion both involved the right acc; (c) subjective beauty and negative emotion both involved the precuneus; (d) subjective ugliness and negative emotion both involved the right inferior frontal gyrus; (e) subjective ugliness alone additionally activated the insula; and (f) subjective beauty alone additionally activated the caudate. |
2016-04-14 |
2023-08-13 |
human |
| Nora C Vetter, Maximilian Pilhatsch, Sarah Weigelt, Stephan Ripke, Michael N Smolk. Mid-adolescent neurocognitive development of ignoring and attending emotional stimuli. Developmental cognitive neuroscience. vol 14. 2016-03-07. PMID:26093849. |
activation of the anterior insula increased across ages for attending positive and ignoring negative emotions. |
2016-03-07 |
2023-08-13 |
human |
| Sahba Besharati, Stephanie J Forkel, Michael Kopelman, Mark Solms, Paul M Jenkinson, Aikaterini Fotopoulo. The affective modulation of motor awareness in anosognosia for hemiplegia: behavioural and lesion evidence. Cortex; a journal devoted to the study of the nervous system and behavior. vol 61. 2015-09-08. PMID:25481471. |
additionally, the insula, putamen and anterior periventricular white matter were associated with less awareness change following the negative emotion induction. |
2015-09-08 |
2023-08-13 |
Not clear |
| Sylvia A Morelli, Jared B Torre, Naomi I Eisenberge. The neural bases of feeling understood and not understood. Social cognitive and affective neuroscience. vol 9. issue 12. 2015-07-20. PMID:24396002. |
ventral striatum and middle insula), while not feeling understood activated neural regions previously associated with negative affect (i.e. |
2015-07-20 |
2023-08-12 |
human |
| M D Wheelock, K R Sreenivasan, K H Wood, L W Ver Hoef, Gopikrishna Deshpande, D C Knigh. Threat-related learning relies on distinct dorsal prefrontal cortex network connectivity. NeuroImage. vol 102 Pt 2. 2015-07-16. PMID:25111474. |
ventromedial pfc, amygdala, and insula) varied with negative affect (i.e. |
2015-07-16 |
2023-08-13 |
Not clear |
| Rhiannon Jones, Joydeep Bhattachary. Alpha activity in the insula accompanies the urge to neutralize in sub-clinical obsessive-compulsive participants. Journal of behavioral addictions. vol 1. issue 3. 2015-07-14. PMID:26165459. |
between-condition comparisons in the high-oc group revealed significantly greater alpha activity in the insula and vlpfc in the negative than the positive condition, which was significantly correlated with both urge to neutralize and later decrease in negative affect. |
2015-07-14 |
2023-08-13 |
human |
| Bryan T Denny, Jin Fan, Xun Liu, Stephanie Guerreri, Sarah Jo Mayson, Liza Rimsky, Antonia S New, Larry J Siever, Harold W Koenigsber. Insula-amygdala functional connectivity is correlated with habituation to repeated negative images. Social cognitive and affective neuroscience. vol 9. issue 11. 2015-07-01. PMID:24170933. |
posterior insula activation during image presentation was correlated with greater negative affect ratings for novel presentations of negative images. |
2015-07-01 |
2023-08-12 |
human |
| Michael P I Becker, Alexander M Nitsch, Ralf Schlösser, Kathrin Koch, Claudia Schachtzabel, Gerd Wagner, Wolfgang H R Miltner, Thomas Straub. Altered emotional and BOLD responses to negative, positive and ambiguous performance feedback in OCD. Social cognitive and affective neuroscience. vol 9. issue 8. 2015-04-10. PMID:23893850. |
findings indicate that both negative and ambiguous performance feedbacks are associated with abnormal negative emotions and altered brain activation, in particular increased insula activation, while activation in the putamen and vmpfc does not differentiate between feedback types in ocd patients. |
2015-04-10 |
2023-08-12 |
Not clear |
| Olga M Klimecki, Susanne Leiberg, Matthieu Ricard, Tania Singe. Differential pattern of functional brain plasticity after compassion and empathy training. Social cognitive and affective neuroscience. vol 9. issue 6. 2015-01-16. PMID:23576808. |
in response to videos depicting human suffering, empathy training, but not memory training (control group), increased negative affect and brain activations in anterior insula and anterior midcingulate cortex-brain regions previously associated with empathy for pain. |
2015-01-16 |
2023-08-12 |
human |