| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Giorgio R Merlo, Stefano Mantero, Ambra A Zaghetto, Paolo Peretto, Sara Paina, Marianna Gozz. The role of Dlx homeogenes in early development of the olfactory pathway. Journal of molecular histology. vol 38. issue 4. 2007-10-19. PMID:17588208. |
olfactory receptor neurons (orn) in the olfactory placodes (op) extend axons towards the forebrain (fb); with innervation taking place at a later time following degradation of the basement membrane. |
2007-10-19 |
2023-08-12 |
Not clear |
| Ambra A Zaghetto, Sara Paina, Stefano Mantero, Natalia Platonova, Paolo Peretto, Serena Bovetti, Adam Puche, Stefano Piccolo, Giorgio R Merl. Activation of the Wnt-beta catenin pathway in a cell population on the surface of the forebrain is essential for the establishment of olfactory axon connections. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 36. 2007-10-02. PMID:17804636. |
these data reveal a novel function for wnt signaling in the establishment of periphery-cns olfactory connections and highlight a complex interplay between cells of different embryonic origin for orn axon connectivity. |
2007-10-02 |
2023-08-12 |
mouse |
| Cory M Root, Julia L Semmelhack, Allan M Wong, Jorge Flores, Jing W Wan. Propagation of olfactory information in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 28. 2007-09-27. PMID:17596338. |
we found a strong link between pn firing and dendritic calcium elevation, the latter of which is tightly correlated with calcium activity in orn axons, supporting the idea of glomerular propagation of olfactory information. |
2007-09-27 |
2023-08-12 |
drosophila_melanogaster |
| Christine Baly, Josiane Aioun, Karine Badonnel, Marie-Christine Lacroix, Didier Durieux, Claire Schlegel, Roland Salesse, Monique Caillo. Leptin and its receptors are present in the rat olfactory mucosa and modulated by the nutritional status. Brain research. vol 1129. issue 1. 2007-03-22. PMID:17169337. |
altogether, these results strongly suggested that leptin, acting as an endocrine or a paracrine factor, could be an important regulator of olfactory function, as a neuromodulator of the olfactory message in cilia of mature olfactory receptors neurons (orn), but also for the homeostasis of this complex tissue, acting on differentiating neurons and on sustentacular cells. |
2007-03-22 |
2023-08-12 |
rat |
| Anandasankar Ray, Wynand van der Goes van Naters, Takashi Shiraiwa, John R Carlso. Mechanisms of odor receptor gene choice in Drosophila. Neuron. vol 53. issue 3. 2007-03-15. PMID:17270733. |
we use computational algorithms and mutational analysis to define positive and negative regulatory elements that are required for selection of odor receptor (or) genes in the proper olfactory organ of drosophila, and we identify an element that is essential for selection in one orn class. |
2007-03-15 |
2023-08-12 |
drosophila_melanogaster |
| Lora B Sweeney, Africa Couto, Ya-Hui Chou, Daniela Berdnik, Barry J Dickson, Liqun Luo, Takaki Komiyam. Temporal target restriction of olfactory receptor neurons by Semaphorin-1a/PlexinA-mediated axon-axon interactions. Neuron. vol 53. issue 2. 2007-02-27. PMID:17224402. |
sema-1a acts nonautonomously to control orn axon-axon interactions, in contrast to its cell-autonomous function in olfactory projection neurons. |
2007-02-27 |
2023-08-12 |
drosophila_melanogaster |
| P Pahn Pataramekin, Esmail Meisam. Cytochrome oxidase staining reveals functionally important activity bands in the olfactory epithelium of newborn rat. Journal of neurocytology. vol 34. issue 3-5. 2006-10-19. PMID:16841167. |
our findings agree with ultrastructural studies showing a presence of mitochondria in knobs, basal portions of orn dendrites and in oe supporting cell apices, suggesting that apical regions of both olfactory and supporting cells near the surfaces are metabolically most active, in odorant detection, signal processing, and detoxification, the latter for supporting cells. |
2006-10-19 |
2023-08-12 |
rat |
| Brian W Lipscomb, Leslie P Tolber. Temporally staggered glomerulus development in the moth Manduca sexta. Chemical senses. vol 31. issue 3. 2006-09-22. PMID:16407570. |
glomeruli, neuropilar structures composed of olfactory receptor neuron (orn) axon terminals and central neuron dendrites, are a common feature of olfactory systems. |
2006-09-22 |
2023-08-12 |
Not clear |
| Jessica L MacDonald, Christopher S Y Gin, A Jane Roskam. Stage-specific induction of DNA methyltransferases in olfactory receptor neuron development. Developmental biology. vol 288. issue 2. 2006-03-24. PMID:16288735. |
dnmt3b is restricted to mitotic olfactory progenitors, whereas dnmt3a is expressed only in post-mitotic immature neurons prior to orn terminal maturation, coincident with histone deacetylase 2 (hdac2), a key downstream effector of methylation-dependent chromatin condensation. |
2006-03-24 |
2023-08-12 |
Not clear |
| Hayato Sasaki, Roseann Berlin, Harriet Bake. Transient expression of tyrosine hydroxylase promoter/reporter gene constructs in the olfactory epithelium of transgenic mice. Journal of neurocytology. vol 33. issue 6. 2006-03-10. PMID:16217623. |
as only a subpopulation of the cells contained olfactory marker protein, indicative of orn maturation, the transgene expressing cells were likely immature neuronal precursors. |
2006-03-10 |
2023-08-12 |
mouse |
| Crestina L Beites, Shimako Kawauchi, Candice E Crocker, Anne L Calo. Identification and molecular regulation of neural stem cells in the olfactory epithelium. Experimental cell research. vol 306. issue 2. 2005-07-26. PMID:15925585. |
we review data suggesting that (1) the orn lineage contains three distinct proliferating cell types--a stem cell and two populations of transit amplifying cells; (2) in established oe, these three cell types are present within the basal cell compartment of the epithelium; and (3) the stem cell that gives rise ultimately to orns may also generate two glial cell types of the primary olfactory pathway: sustentacular cells (sus), which lie within oe proper; and olfactory ensheathing cells (oec), which envelope the olfactory nerve. |
2005-07-26 |
2023-08-12 |
Not clear |
| Aaron L Goldman, Wynand Van der Goes van Naters, Derek Lessing, Coral G Warr, John R Carlso. Coexpression of two functional odor receptors in one neuron. Neuron. vol 45. issue 5. 2005-04-12. PMID:15748842. |
here we construct a receptor-to-neuron map for an entire olfactory organ in drosophila and find that two receptor genes are coexpressed in one class of orn. |
2005-04-12 |
2023-08-12 |
drosophila_melanogaster |
| Detlev Schild, Ivan Manzin. Cascades of response vectors of olfactory receptor neurons in Xenopus laevis tadpoles. The European journal of neuroscience. vol 20. issue 8. 2004-12-21. PMID:15450090. |
we first show that, on the one hand, the number of 204 orn classes (out of 283 recorded orns) cannot be explained by a random expression pattern of olfactory receptors (ors). |
2004-12-21 |
2023-08-12 |
xenopus_laevis |
| Anne Hansen, Karl T Anderson, Thomas E Finge. Differential distribution of olfactory receptor neurons in goldfish: structural and molecular correlates. The Journal of comparative neurology. vol 477. issue 4. 2004-10-21. PMID:15329885. |
the olfactory system of many terrestrial vertebrates comprises a main olfactory organ and a vomeronasal organ each containing a morphologically distinct type of olfactory receptor neuron (orn). |
2004-10-21 |
2023-08-12 |
Not clear |
| Carmen Quero, Josep Bau, Angel Guerrero, Michel Reno. Responses of the olfactory receptor neurons of the corn stalk borer Sesamia nonagrioides to components of the pheromone blend and their inhibition by a trifluoromethyl ketone analogue of the main component. Pest management science. vol 60. issue 7. 2004-10-18. PMID:15260305. |
two types of olfactory hairs and three types of olfactory receptor neurons (orn) have been characterized on the antennae of male sesamia nonagrioides lef for the first time. |
2004-10-18 |
2023-08-12 |
Not clear |
| Takaki Komiyama, John R Carlson, Liqun Lu. Olfactory receptor neuron axon targeting: intrinsic transcriptional control and hierarchical interactions. Nature neuroscience. vol 7. issue 8. 2004-09-30. PMID:15247920. |
here we show in drosophila that the pou transcription factor acj6 controls the axon targeting specificity of a subset of orn classes, as defined by the olfactory receptors that they express. |
2004-09-30 |
2023-08-12 |
drosophila_melanogaster |
| Ivan Manzini, Detlev Schil. Classes and narrowing selectivity of olfactory receptor neurons of Xenopus laevis tadpoles. The Journal of general physiology. vol 123. issue 2. 2004-09-28. PMID:14744986. |
we discuss the narrowing of orn selectivity over stages in the context of expression of olfactory receptors. |
2004-09-28 |
2023-08-12 |
xenopus_laevis |
| Catherine M Cowan, A Jane Roskam. Caspase-3 and caspase-9 mediate developmental apoptosis in the mouse olfactory system. The Journal of comparative neurology. vol 474. issue 1. 2004-07-06. PMID:15156583. |
in the mouse olfactory system, caspase-3 and -9 are expressed in olfactory receptor neurons (orns) of adult mice, and their selective retrograde activation drives orn apoptosis following ablation of their target, the olfactory bulb (ob). |
2004-07-06 |
2023-08-12 |
mouse |
| Curtis William Balmer, Anthony-Samuel LaManti. Loss of Gli3 and Shh function disrupts olfactory axon trajectories. The Journal of comparative neurology. vol 472. issue 3. 2004-05-24. PMID:15065125. |
loss of gli3 or shh function does not compromise several aspects of olfactory receptor neuron (orn) and olfactory ensheathing cell maturation; however, directed outgrowth of orn axons and their initial targeting to the telencephalon is altered. |
2004-05-24 |
2023-08-12 |
Not clear |
| Curtis William Balmer, Anthony-Samuel LaManti. Loss of Gli3 and Shh function disrupts olfactory axon trajectories. The Journal of comparative neurology. vol 472. issue 3. 2004-05-24. PMID:15065125. |
thus, two genes that influence induction and subsequent differentiation of craniofacial structures and the forebrain have distinct consequences for orn axon growth during the initial genesis of the olfactory pathway. |
2004-05-24 |
2023-08-12 |
Not clear |