| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Emre Mısır, Güvem Gümüş Aka. Synaptic dysfunction in schizophrenia. Synapse (New York, N.Y.). 2023-05-21. PMID:37210696. |
schizophrenia is a chronic disease presented with psychotic symptoms, negative symptoms, impairment in the reward system, and widespread neurocognitive deterioration. |
2023-05-21 |
2023-08-14 |
Not clear |
| Erin K Moran, Caroline Prevost, Adam J Culbreth, Deanna M Barc. Effort-cost decision-making in psychotic and mood disorders. Journal of psychopathology and clinical science. 2023-04-20. PMID:37079841. |
we found that people with schizophrenia and bipolar disorder showed a reduced willingness to expend physical effort at high reward values relative to controls, while as a group, those with depression showed no differences relative to controls. |
2023-04-20 |
2023-08-14 |
human |
| Susanna L Fryer, Tobias F Marton, Brian J Roach, Clay B Holroyd, Samantha V Abram, Ken J Lau, Judith M Ford, John R McQuaid, Daniel H Mathalo. Alpha Event-Related Desynchronization During Reward Processing in Schizophrenia. Biological psychiatry. Cognitive neuroscience and neuroimaging. 2023-04-12. PMID:37045705. |
alpha event-related desynchronization during reward processing in schizophrenia. |
2023-04-12 |
2023-08-14 |
Not clear |
| Susanna L Fryer, Tobias F Marton, Brian J Roach, Clay B Holroyd, Samantha V Abram, Ken J Lau, Judith M Ford, John R McQuaid, Daniel H Mathalo. Alpha Event-Related Desynchronization During Reward Processing in Schizophrenia. Biological psychiatry. Cognitive neuroscience and neuroimaging. 2023-04-12. PMID:37045705. |
alterations in the brain's reward system may underlie motivation and pleasure deficits in schizophrenia (sz). |
2023-04-12 |
2023-08-14 |
Not clear |
| Xuan Wang, Yinghao Zhang, Jia Huang, Yi Wang, Yanzhe Niu, Simon S Y Lui, Li Hui, Raymond C K Cha. Revisiting reward impairments in schizophrenia spectrum disorders: a systematic review and meta-analysis for neuroimaging findings. Psychological medicine. 2023-03-30. PMID:36994747. |
abnormal reward functioning is central to anhedonia and amotivation symptoms of schizophrenia (scz). |
2023-03-30 |
2023-08-14 |
Not clear |
| Paola Fuentes-Claramonte, Maria Angeles Garcia-Leon, Pilar Salgado-Pineda, Núria Ramiro, Joan Soler-Vidal, Maria Llanos Torres, Ramon Cano, Isabel Argila-Plaza, Francesco Panicali, Carmen Sarri, Núria Jaurrieta, Manel Sánchez, Ester Boix-Quintana, Auria Albacete, Teresa Maristany, Salvador Sarró, Joaquim Raduà, Peter J McKenna, Raymond Salvador, Edith Pomarol-Clote. Do the negative symptoms of schizophrenia reflect reduced responsiveness to reward? Examination using a reward prediction error (RPE) task. Psychological medicine. 2023-03-29. PMID:36987680. |
do the negative symptoms of schizophrenia reflect reduced responsiveness to reward? |
2023-03-29 |
2023-08-14 |
Not clear |
| Huaigui Liu, Wei Li, Nana Liu, Jie Tang, Lixin Sun, Jiayuan Xu, Yuan Ji, Yingying Xie, Hao Ding, Zhaoxiang Ye, Chunshui Yu, Wen Qi. Structural covariances of prefrontal subregions selectively associate with dopamine-related gene coexpression and schizophrenia. Cerebral cortex (New York, N.Y. : 1991). 2023-03-19. PMID:36935097. |
moreover, based on a schizophrenia postmortem expression dataset, we found that the da genes coexpression of schizophrenia was significantly reduced between the middle frontal gyrus and hippocampus, in which 21 da genes showed significantly unsynchronized expression changes, and the 21 genes' brain expression were enriched in brain activity invoked by working memory, reward, speech production, and episodic memory. |
2023-03-19 |
2023-08-14 |
human |
| Ryan Sai Ting Chu, Co Co Ho Yi Tong, Corine Sau Man Wong, Wing Chung Chang, Wesley Chor Yin Tang, Charlotte Cheuk Lok Chan, Simon S Y Lui, Lai Ming Hui, Yi Nam Suen, Kit Wa Chan, Ho Ming Lee, Eric Yu Hai Che. Effort-based decision making in schizotypy and its relationship with amotivation and psychosocial functioning. Frontiers in psychiatry. vol 14. 2023-03-06. PMID:36873206. |
suboptimal effort-based decision-making with reduced willingness to expend effort for high-probability/high-value reward is observed in schizophrenia patients and is related to diminished motivation, but is understudied in schizotypy. |
2023-03-06 |
2023-08-14 |
Not clear |
| John R Purcell, Joshua W Brown, Rachel L Tullar, Bess F Bloomer, Dae-Jin Kim, Alexandra B Moussa-Tooks, Katherine Dolan-Bennett, Brianna M Bangert, Krista M Wisner, Nancy B Lundin, Brian F O'Donnell, William P Hetric. Insular and Striatal Correlates of Uncertain Risky Reward Pursuit in Schizophrenia. Schizophrenia bulletin. 2023-03-04. PMID:36869757. |
insular and striatal correlates of uncertain risky reward pursuit in schizophrenia. |
2023-03-04 |
2023-08-14 |
human |
| Mette Ødegaard Nielsen, Egill Rostrup, Rikke Hilker, Christian Legind, Simon Anhøj, Trevor William Robbins, Barbara J Sahakian, Birgitte Fagerlund, Birte Glenthø. Reward Processing as an Indicator of Vulnerability or Compensatory Resilience in Psychoses? Results From a Twin Study. Biological psychiatry global open science. vol 3. issue 1. 2023-01-30. PMID:36712565. |
findings of reward disturbances in unaffected relatives of patients with schizophrenia suggest reward disturbances as an endophenotype for schizophrenia. |
2023-01-30 |
2023-08-14 |
Not clear |
| Jianguang Zeng, Jiangnan Yan, Hengyi Cao, Yueyue Su, Yuan Song, Ya Luo, Xun Yan. Neural substrates of reward anticipation and outcome in schizophrenia: a meta-analysis of fMRI findings in the monetary incentive delay task. Translational psychiatry. vol 12. issue 1. 2022-10-16. PMID:36244990. |
dysfunction of the mesocorticolimbic dopaminergic reward system is a core feature of schizophrenia (sz), yet its precise contributions to different stages of reward processing and their relevance to disease symptomology are not fully understood. |
2022-10-16 |
2023-08-14 |
Not clear |
| Thanh P Le, Michael F Green, Junghee Lee, Peter E Clayson, Amy M Jimenez, Eric A Reavis, Jonathan K Wynn, William P Hora. Aberrant reward processing to positive versus negative outcomes across psychotic disorders. Journal of psychiatric research. vol 156. 2022-10-06. PMID:36201975. |
several studies of reward processing in schizophrenia have shown reduced sensitivity to positive, but not negative, outcomes although inconsistencies have been reported. |
2022-10-06 |
2023-08-14 |
Not clear |
| Thanh P Le, Michael F Green, Junghee Lee, Peter E Clayson, Amy M Jimenez, Eric A Reavis, Jonathan K Wynn, William P Hora. Aberrant reward processing to positive versus negative outcomes across psychotic disorders. Journal of psychiatric research. vol 156. 2022-10-06. PMID:36201975. |
the current findings suggest reward processing disturbances, particularly decreased sensitivity to positive outcomes, extend beyond schizophrenia to a broader spectrum of psychotic disorders and relate to important clinical outcomes. |
2022-10-06 |
2023-08-14 |
Not clear |
| Mariia Kaliuzhna, Matthias Kirschner, Philippe N Tobler, Stefan Kaise. Comparing adaptive coding of reward in bipolar I disorder and schizophrenia. Human brain mapping. 2022-09-16. PMID:36111883. |
comparing adaptive coding of reward in bipolar i disorder and schizophrenia. |
2022-09-16 |
2023-08-14 |
human |
| Mariia Kaliuzhna, Matthias Kirschner, Philippe N Tobler, Stefan Kaise. Comparing adaptive coding of reward in bipolar I disorder and schizophrenia. Human brain mapping. 2022-09-16. PMID:36111883. |
deficits in neural processing of reward have been described in both bipolar disorder (bd) and schizophrenia (sz), but it remains unclear to what extent these deficits are caused by similar mechanisms. |
2022-09-16 |
2023-08-14 |
human |
| Stephen J Kaar, Ilinca Angelescu, Matthew M Nour, Tiago Reis Marques, Alice Sharman, Anil Sajjala, John Hutchison, Philip McGuire, Charles Large, Oliver D Howe. The effects of AUT00206, a novel Kv3.1/3.2 potassium channel modulator, on task-based reward system activation: a test of mechanism in schizophrenia. Psychopharmacology. 2022-09-12. PMID:36094619. |
the effects of aut00206, a novel kv3.1/3.2 potassium channel modulator, on task-based reward system activation: a test of mechanism in schizophrenia. |
2022-09-12 |
2023-08-14 |
human |
| Stephen J Kaar, Ilinca Angelescu, Matthew M Nour, Tiago Reis Marques, Alice Sharman, Anil Sajjala, John Hutchison, Philip McGuire, Charles Large, Oliver D Howe. The effects of AUT00206, a novel Kv3.1/3.2 potassium channel modulator, on task-based reward system activation: a test of mechanism in schizophrenia. Psychopharmacology. 2022-09-12. PMID:36094619. |
the pathophysiology of schizophrenia involves abnormal reward processing, thought to be due to disrupted striatal and dopaminergic function. |
2022-09-12 |
2023-08-14 |
human |
| Felix Brandl, Franziska Knolle, Mihai Avram, Claudia Leucht, Igor Yakushev, Josef Priller, Stefan Leucht, Sibylle Ziegler, Klaus Wunderlich, Christian Sor. Negative symptoms, striatal dopamine, and model-free reward decision-making in schizophrenia. Brain : a journal of neurology. 2022-07-25. PMID:35875972. |
negative symptoms, striatal dopamine, and model-free reward decision-making in schizophrenia. |
2022-07-25 |
2023-08-14 |
human |
| Felix Brandl, Franziska Knolle, Mihai Avram, Claudia Leucht, Igor Yakushev, Josef Priller, Stefan Leucht, Sibylle Ziegler, Klaus Wunderlich, Christian Sor. Negative symptoms, striatal dopamine, and model-free reward decision-making in schizophrenia. Brain : a journal of neurology. 2022-07-25. PMID:35875972. |
we hypothesized that in patients with schizophrenia during psychotic remission, impaired influences of both model-based and model-free reward predictions on decision-making ('reward prediction influence', rpi) underlie negative symptoms. |
2022-07-25 |
2023-08-14 |
human |
| Sugai Liang, Yue Wu, Li Hanxiaoran, Andrew J Greenshaw, Tao L. Anhedonia in Depression and Schizophrenia: Brain Reward and Aversion Circuits. Neuropsychiatric disease and treatment. vol 18. 2022-07-15. PMID:35836582. |
anhedonia in depression and schizophrenia: brain reward and aversion circuits. |
2022-07-15 |
2023-08-14 |
Not clear |