| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marek Lapka, Chrysostomos Charalambous, Anna Khryakova, Alina Certilina, Jiri Novotny, Lucie Hejnova, Magdalena Sustkova-Fiserov. Ghrelin/GHS-R1A antagonism in memory test and its effects on central molecular signaling involved in addiction in rats. Pharmacology, biochemistry, and behavior vol issue 2023 36870422 |
these results imply, that the ghs-r1a antagonist/jmv2959 might reduce/prevent some of the memory-linked molecular changes elicited by methamphetamine addiction within brain structures associated with memory (hipp), reward (nac), and motivation (mpfc), which may contribute to the previously observed significant jmv2959-induced reduction of the methamphetamine self-administration and drug-seeking behavior in the same animals. |
2023-03-04 |
2023-03-06 |
rat |
| Eric Y Choi, Daniela Franco, Catherine A Stapf, Madeleine Gordin, Amanda Chow, Kara K Cover, Ramesh Chandra, Mary Kay Lob. Inducible CRISPR Epigenome Systems Mimic Cocaine Induced Bidirectional Regulation of Nab2 and Egr3. The Journal of neuroscience : the official journal of the Society for Neuroscience vol issue 2023 36849419 |
the nucleus accumbens (nac) is a major brain hub mediating reward behavior. |
2023-02-27 |
2023-03-06 |
Not clear |
| Hillary A Wadsworth, Elizabeth Q Anderson, Benjamin M Williams, Joakim W Ronstr\\xc3\\xb6m, Janna K Moen, Anna M Lee, J Michael McIntosh, Jie Wu, Jordan T Yorgason, Scott C Steffense. Role of \\xce\\xb16-Nicotinic Receptors in Alcohol-Induced GABAergic Synaptic Transmission and Plasticity to Cholinergic Interneurons in the Nucleus Accumbens. Molecular neurobiology vol issue 2023 36802012 |
the prevailing view is that enhancement of dopamine (da) transmission in the mesolimbic system, consisting of da neurons in the ventral tegmental area (vta) that project to the nucleus accumbens (nac), underlies the reward properties of ethanol (etoh) and nicotine (nic). |
2023-02-21 |
2023-03-06 |
mouse |
| Gaowei Chen, Shishi Lai, Guo Bao, Jincan Ke, Xiaogao Meng, Shanshan Lu, Xiaocong Wu, Hua Xu, Fengyi Wu, Yu Xu, Fang Xu, Guo-Qiang Bi, Guangdun Peng, Kuikui Zhou, Yingjie Zh. Distinct reward processing by subregions of the nucleus accumbens. Cell reports vol 42 issue 2 2023 36753418 |
the nucleus accumbens (nac) plays an important role in motivation and reward processing. |
2023-02-08 |
2023-03-06 |
Not clear |
| Gaowei Chen, Shishi Lai, Guo Bao, Jincan Ke, Xiaogao Meng, Shanshan Lu, Xiaocong Wu, Hua Xu, Fengyi Wu, Yu Xu, Fang Xu, Guo-Qiang Bi, Guangdun Peng, Kuikui Zhou, Yingjie Zh. Distinct reward processing by subregions of the nucleus accumbens. Cell reports vol 42 issue 2 2023 36753418 |
however, how reward is encoded in individual nac neurons remains unclear. |
2023-02-08 |
2023-03-06 |
Not clear |
| Gaowei Chen, Shishi Lai, Guo Bao, Jincan Ke, Xiaogao Meng, Shanshan Lu, Xiaocong Wu, Hua Xu, Fengyi Wu, Yu Xu, Fang Xu, Guo-Qiang Bi, Guangdun Peng, Kuikui Zhou, Yingjie Zh. Distinct reward processing by subregions of the nucleus accumbens. Cell reports vol 42 issue 2 2023 36753418 |
using in\xc2\xa0vivo single-cell resolution calcium imaging, we find diverse patterns of reward encoding in the medial and lateral shell subdivision of the nac (nacmed and naclat, respectively). |
2023-02-08 |
2023-03-06 |
Not clear |
| Qiang Lyu, Hecun Zou, Li Luo, Wei Liu, Xiang He, Fei-Fei Shan. The Role of eIF5A1 in LPS-Induced Neuronal Remodeling of the Nucleus Accumbens in the Depression. Journal of integrative neuroscience vol 22 issue 1 2023 36722231 |
the nucleus accumbens (nac) is a key region in the brain that integrates reward signals. |
2023-02-01 |
2023-03-06 |
Not clear |
| Julianna Cavallaro, Jenna Yeisley, Ba\\xc5\\x9fak Akdo\\xc7\\xa7an, Joseph Floeder, Peter D Balsam, Eduardo F Gall. Dopamine D2 receptors in nucleus accumbens cholinergic interneurons increase impulsive choice. bioRxiv : the preprint server for biology vol issue 2023 36711450 |
here, we show that d2r upregulation in cins of the mouse nac increases impulsive choice as measured in a delay discounting task without affecting reward magnitude sensitivity or interval timing. |
2023-01-30 |
2023-01-31 |
mouse |
| Yu-Chen Chan, Tai-Li Cho. Effective connectivity of the amygdala during the consumption of erotic, sexual humor, and monetary rewards with a DCM-PEB approach. PloS one vol 17 issue 12 2022 36580445 |
the amygdala, nac, and lofc are major dopaminergic targets with known roles in the reward circuitry. |
2022-12-29 |
2023-01-30 |
Not clear |
| Hong Zhou, Jiayu Zhu, Jie Jia, Wei Xiang, Hualing Peng, Yuejin Zhang, Bo Liu, Yangling Mu, Yisheng L. The antidepressant effect of nucleus accumbens deep brain stimulation is mediated by parvalbumin-positive interneurons in the dorsal dentate gyrus. Neurobiology of stress vol 21 issue 2022 36532368 |
the nucleus accumbens (nac) is a crucial region in the reward circuit and is related to anhedonia, the pivotal symptom of major depression disorder (mdd). |
2022-12-19 |
2023-01-30 |
mouse |
| He Chen, Limei Chen, Zhirong Yuan, Jiajie Yuan, Yitong Li, Yuesi Xu, Jieyi Wu, Lu Zhang, Guohua Wang, Juan L. Glutamate receptor-interacting protein 1 in D1- and D2-dopamine receptor-expressing medium spiny neurons differentially regulates cocaine acquisition, reinstatement, and associated spine plasticity. Frontiers in cellular neuroscience vol 16 issue 2022 36406750 |
in the nac, d1-medium spiny neurons (msns) encode cocaine reward, whereas d2-msns encode aversive responses in drug addiction. |
2022-11-21 |
2023-01-30 |
Not clear |
| Wanqi Che. Neural circuits provide insights into reward and aversion. Frontiers in neural circuits vol 16 issue 2022 36389177 |
the aim of this paper is to summarize the latest findings on the mechanisms of the neural circuits associated with reward and aversion in a review of previous studies with a focus on the ventral tegmental area (vta), nucleus accumbens (nac), and basal forebrain (bf). |
2022-11-17 |
2023-01-30 |
Not clear |
| Xuansong Mao, Kolter B Grigsby, Taylor J Kelty, Nathan R Kerr, Thomas E Childs, Frank W Boot. Transcriptomic analysis reveals novel molecular signaling networks in response to nucleus accumbens AP-1 inhibition in rats selectively bred for low voluntary wheel running behavior. Neuroscience vol issue 2022 36395916 |
transcriptome analysis of the nucleus accumbens (nac; a brain region critical for pa reward and motivation) was performed to further determine molecular responses to intra-nac ap-1 inhibition in these rat lines. |
2022-11-17 |
2023-01-30 |
rat |
| Jinlan Zhao, Lihong Ye, Zuyi Liu, Yongfei Cui, Di Deng, Shasha Bai, Lei Yang, Yafei Shi, Zhongqiu Liu, Rong Zhan. Protective Effects of Resveratrol on Adolescent Social Isolation-Induced Anxiety-Like Behaviors via Modulating Nucleus Accumbens Spine Plasticity and Mitochondrial Function in Female Rats. Nutrients vol 14 issue 21 2022 36364807 |
the nucleus accumbens (nac) is an important reward center implicated in psychiatric disorders. |
2022-11-11 |
2023-01-30 |
rat |
| William C Griffin, Marcelo F Lopez, John J Woodward, Howard C Becke. Alcohol Dependence and the Ventral Hippocampal Influence on Alcohol Drinking in Male Mice. Alcohol (Fayetteville, N.Y.) vol issue 2022 36328184 |
facilitated by its connectivity with other parts of the brain such as the nucleus accumbens (nac), the ventral hippocampus (vhc) supports many behaviors, including those related to reward seeking and addiction. |
2022-11-03 |
2023-01-30 |
mouse |
| Kuikui Zhou, Hua Xu, Shanshan Lu, Shaolei Jiang, Guoqiang Hou, Xiaofei Deng, Miao He, Yingjie Zh. Reward and aversion processing by input-defined parallel nucleus accumbens circuits in mice. Nature communications vol 13 issue 1 2022 36271048 |
the nucleus accumbens (nac) is critical in mediating reward seeking and is also involved in negative emotion processing, but the cellular and circuitry mechanisms underlying such opposing behaviors remain elusive. |
2022-10-21 |
2023-01-30 |
mouse |
| Bowen Tan, Tobias N\\xc3\\xb6bauer, Caleb J Browne, Eric J Nestler, Alipasha Vaziri, Jeffrey M Friedma. Dynamic processing of hunger and thirst by common mesolimbic neural ensembles. Proceedings of the National Academy of Sciences of the United States of America vol 119 issue 43 2022 36252036 |
the nucleus accumbens (nac) is a canonical reward center that regulates feeding and drinking but it is not known whether these behaviors are mediated by same or different neurons. |
2022-10-17 |
2023-01-30 |
mouse |
| Bowen Tan, Tobias N\\xc3\\xb6bauer, Caleb J Browne, Eric J Nestler, Alipasha Vaziri, Jeffrey M Friedma. Dynamic processing of hunger and thirst by common mesolimbic neural ensembles. Proceedings of the National Academy of Sciences of the United States of America vol 119 issue 43 2022 36252036 |
in aggregate, these data show that a highly overlapping set of d1 and d2 neurons in nac detect food and water reward and elicit concordant responses to hunger and thirst. |
2022-10-17 |
2023-01-30 |
mouse |
| Tong-Yu Liang, Hua Zhou, Yan-Gang Su. Distinct roles of dopamine receptor subtypes in the nucleus accumbens during itch signal processing. The Journal of neuroscience : the official journal of the Society for Neuroscience vol issue 2022 36241382 |
ventral tegmental area (vta) dopaminergic neurons, which are well known for their central roles in reward and motivation-related behaviors, have been shown to participate in itch processing via their projection to the nucleus accumbens (nac). |
2022-10-14 |
2023-01-30 |
mouse |
| Daozhong Jin, Hong Chen, Shao-Rui Chen, Hui-Lin Pa. \\xce\\xb12\\xce\\xb4-1 Protein drives opioid-induced conditioned reward and synaptic NMDA receptor hyperactivity in the nucleus accumbens. Journal of neurochemistry vol issue 2022 36222452 |
glutamate nmda receptors (nmdars) in the nucleus accumbens (nac) are critically involved in drug dependence and reward. |
2022-10-12 |
2023-01-30 |
mouse |