| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaolong Peng, Dillon J Connolly, Falon Sutton, John Robinson, Brenna Baker-Vogel, Edward B Short, Bashar W Badra. Non-invasive suppression of the human nucleus accumbens (NAc) with transcranial focused ultrasound (tFUS) modulates the reward network: a pilot study. Frontiers in human neuroscience. vol 18. 2024-04-17. PMID:38628972. |
non-invasive suppression of the human nucleus accumbens (nac) with transcranial focused ultrasound (tfus) modulates the reward network: a pilot study. |
2024-04-17 |
2024-04-19 |
human |
| Xiaolong Peng, Dillon J Connolly, Falon Sutton, John Robinson, Brenna Baker-Vogel, Edward B Short, Bashar W Badra. Non-invasive suppression of the human nucleus accumbens (NAc) with transcranial focused ultrasound (tFUS) modulates the reward network: a pilot study. Frontiers in human neuroscience. vol 18. 2024-04-17. PMID:38628972. |
the nucleus accumbens (nac) is a key node of the brain reward circuit driving reward-related behavior. |
2024-04-17 |
2024-04-19 |
human |
| Xiaolong Peng, Dillon J Connolly, Falon Sutton, John Robinson, Brenna Baker-Vogel, Edward B Short, Bashar W Badra. Non-invasive suppression of the human nucleus accumbens (NAc) with transcranial focused ultrasound (tFUS) modulates the reward network: a pilot study. Frontiers in human neuroscience. vol 18. 2024-04-17. PMID:38628972. |
however, there is currently no evidence showing how the brain activity of nac and brain functional connectivity within the reward network neuromodulated by tfus on the nac. |
2024-04-17 |
2024-04-19 |
human |
| Philipp Mews, Lucas Sosnick, Ashik Gurung, Simone Sidoli, Eric J Nestle. Decoding cocaine-induced proteomic adaptations in the mouse nucleus accumbens. Science signaling. vol 17. issue 832. 2024-04-16. PMID:38626009. |
the nucleus accumbens (nac), a region that is integral to the brain's reward circuitry, plays a crucial role in the initiation and continuation of maladaptive behaviors that are intrinsic to cud. |
2024-04-16 |
2024-04-19 |
mouse |
| Hannah F Waguespack, Jessica T Jacobs, Janis Park, Carolina Campos-Rodriguez, Rafael S Maior, Patrick A Forcelli, Ludise Malkov. Pharmacological inhibition of the nucleus accumbens increases dyadic social interaction in macaques. eNeuro. 2024-04-04. PMID:38575350. |
the nucleus accumbens (nac) is a central component of the brain circuitry that mediates motivated behavior, including reward processing. |
2024-04-04 |
2024-04-07 |
Not clear |
| Shelby Travaglianti, Ahmed Alotaibi, Woonyen Wong, Magid Abou-Gharbia, Wayne Childers, Youssef Sar. Effects of novel GLT-1 modulator, MC-100093, on neuroinflammatory and neurotrophic biomarkers in mesocorticolimbic brain regions of male alcohol preferring rats exposed chronically to ethanol. Brain research bulletin. 2024-04-03. PMID:38570076. |
chronic ethanol consumption can lead to increased extracellular glutamate concentrations in key reward brain regions, such as medial prefrontal cortex (mpfc) and nucleus accumbens (nac), and consequently leading to oxidative stress and neuroinflammation. |
2024-04-03 |
2024-04-06 |
rat |
| Florian Schoukroun, Katia Befort, Romain Bourd. The rostromedial tegmental nucleus gates fat overconsumption through ventral tegmental area output in male rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2024-04-03. PMID:38570645. |
similar to addictive drugs, such foods activate the brain's reward circuit, involving mesolimbic dopaminergic projections from the ventral tegmental area (vta) to the nucleus accumbens (nac) and the prefrontal cortex. |
2024-04-03 |
2024-04-06 |
rat |
| Freddyson J Martínez-Rivera, Leanne M Holt, Angélica Minier-Toribio, Molly Estill, Szu-Ying Yeh, Solange Tofani, Rita Futamura, Caleb J Browne, Philipp Mews, Li Shen, Eric J Nestle. Transcriptional characterization of cocaine withdrawal versus extinction within nucleus accumbens. bioRxiv : the preprint server for biology. 2024-04-01. PMID:38559084. |
cocaine use disorder (cud) exemplifies this phenomenon in which neurobiological modifications hijack brain reward regions such as the nucleus accumbens (nac) to manifest craving and withdrawal-like symptoms. |
2024-04-01 |
2024-04-04 |
rat |
| Pan Zhang, Yangke Mao, Liangchao Gao, Zilei Tian, Ruirui Sun, Yuqi He, Peihong Ma, Beihong Dou, Yuan Chen, Xiabing Zhang, Zhaoxuan He, Tao Yin, Fang Zen. Abnormal functional connectivity of the reward circuit associated with early satiety in patients with postprandial distress syndrome. Appetite. vol 197. 2024-03-29. PMID:38552365. |
to investigate the correlation between reward circuit and symptom severity of pds patients, seed (nucleus accumbens, nac, a key node in the reward circuit) based resting-state functional connectivity (fc) was applied in the neuroimaging data analysis. |
2024-03-29 |
2024-04-01 |
Not clear |
| Alaa Khayat, Rami Yak. Activation of nucleus accumbens projections to the ventral tegmental area alters molecular signaling and neurotransmission in the reward system. Frontiers in molecular neuroscience. vol 17. 2024-03-26. PMID:38528956. |
the nucleus accumbens (nac) and the ventral tegmental area (vta) are integral brain regions involved in reward processing and motivation, including responses to drugs of abuse. |
2024-03-26 |
2024-03-28 |
Not clear |
| Roman Walle, Anna Petitbon, Giulia R Fois, Christophe Varin, Enrica Montalban, Lola Hardt, Andrea Contini, Maria Florencia Angelo, Mylène Potier, Rodrigue Ortole, Asma Oummadi, Véronique De Smedt-Peyrusse, Roger A Adan, Bruno Giros, Francis Chaouloff, Guillaume Ferreira, Alban de Kerchove d'Exaerde, Fabien Ducrocq, François Georges, Pierre Trifilief. Nucleus accumbens D1- and D2-expressing neurons control the balance between feeding and activity-mediated energy expenditure. Nature communications. vol 15. issue 1. 2024-03-22. PMID:38514654. |
using chemogenetic manipulations in male mice, we found that activity of dopamine d1 receptor-expressing neurons of the nac core subregion facilitated effort for a food reward as well as voluntary exercise, but decreased food intake, while d2-expressing neurons have opposite effects. |
2024-03-22 |
2024-03-24 |
mouse |
| Julia M Kirkland, Erin L Edgar, Ishan Patel, Paul Feustel, Sophie Belin, Ashley M Kope. Synaptic pruning during adolescence shapes adult social behavior in both males and females. Developmental psychobiology. vol 66. issue 3. 2024-03-04. PMID:38433422. |
the nucleus accumbens (nac) is an intermediate reward relay center that develops during adolescence and mediates both social behaviors and dopaminergic signaling. |
2024-03-04 |
2024-03-06 |
human |
| Nicholas Pintori, Alessandro Piva, Francesca Mottarlini, Fernando Castillo Díaz, Coralie Maggi, Lucia Caffino, Fabio Fumagalli, Cristiano Chiamuler. Brief exposure to enriched environment rapidly shapes the glutamate synapses in the rat brain: A metaplastic fingerprint. The European journal of neuroscience. 2024-02-20. PMID:38378276. |
adult male sprague-dawley rats were exposed to ee for 22 h and the expression of critical elements of the glutamate synapse was measured 2 h after the end of ee in the medial prefrontal cortex (mpfc), nucleus accumbens (nac) and hippocampus (hipp) brain areas, which are critical for reward and memory. |
2024-02-20 |
2024-02-23 |
rat |
| Catarina Deseyve, Ana Verónica Domingues, Tawan T A Carvalho, Gisela Armada, Raquel Correia, Natacha Vieitas-Gaspar, Marcelina Wezik, Luísa Pinto, Nuno Sousa, Bárbara Coimbra, Ana João Rodrigues, Carina Soares-Cunh. Nucleus accumbens neurons dynamically respond to appetitive and aversive associative learning. Journal of neurochemistry. 2024-02-06. PMID:38317429. |
this association is partially mediated by the nucleus accumbens (nac), a key brain region of the reward circuit that is mainly composed by gabaergic medium spiny neurons (msns), that express either dopamine receptor d1 or d2. |
2024-02-06 |
2024-02-09 |
mouse |
| R Heijkoop, J F Lalanza, M Solanas, A Álvarez-Monell, A Subias-Gusils, R M Escorihuela, E M S Snoere. Changes in reward-induced neural activity upon Cafeteria Diet consumption. Physiology & behavior. 2024-02-02. PMID:38307359. |
to this end, rats were exposed to a 6-week diet with either standard chow, or ad libitum daily access to caf diet, 30% restricted but daily access to caf diet, or one-day-a-week (intermittent) ad libitum access to caf diet, after which c-fos expression in the nucleus accumbens (nac), prefrontal cortex (pfc), and ventral tegmental area (vta) following consumption of a caf reward of choice was examined. |
2024-02-02 |
2024-02-05 |
rat |
| Leanne M Holt, Trevonn M Gyles, Eric M Parise, Angelica Minier-Toribio, Tamara Markovic, Matthew Rivera, Szu-Ying Yeh, Eric J Nestle. Astrocytic CREB in nucleus accumbens promotes susceptibility to chronic stress. bioRxiv : the preprint server for biology. 2024-01-31. PMID:38293227. |
despite this, little is known about the transcriptional responses to stress of astrocytes within the nucleus accumbens (nac), a key brain reward region, and their influence on behavioral outcomes. |
2024-01-31 |
2024-02-02 |
human |
| Khairunisa Mohamad Ibrahim, Nicolas Massaly, Hye-Jean Yoon, Rossana Sandoval, Allie J Widman, Robert J Heuermann, Sidney Williams, William Post, Sulan Pathiranage, Tania Lintz, Azra Zec, Ashley Park, Waylin Yu, Thomas L Kash, Robert W Gereau, Jose A Moró. Dorsal hippocampus to nucleus accumbens projections drive reinforcement via activation of accumbal dynorphin neurons. Nature communications. vol 15. issue 1. 2024-01-29. PMID:38286800. |
the nucleus accumbens (nac), a central structure in the mesolimbic reward pathway, integrates the salience of aversive and rewarding stimuli. |
2024-01-29 |
2024-02-01 |
Not clear |
| Runxin Lv, Min Cai, Nailong Tang, Yifan Shi, Yuyu Zhang, Nian Liu, Tianle Han, Yaochi Zhang, Huaning Wan. Active versus sham DLPFC-NAc rTMS for depressed adolescents with anhedonia using resting-state functional magnetic resonance imaging (fMRI): a study protocol for a randomized placebo-controlled trial. Trials. vol 25. issue 1. 2024-01-13. PMID:38218932. |
previous researches have revealed a link between anhedonia and abnormalities within the reward circuitry, making the nucleus accumbens (nac) a potential target for treatment. |
2024-01-13 |
2024-01-16 |
Not clear |
| Seyedeh-Najmeh Katebi, Anahita Torkaman-Boutorabi, Esmail Riahi, Abbas Haghparas. N-acetylcysteine attenuates accumbal core neuronal activity in response to morphine in the reinstatement of morphine CPP in morphine extinguished rats. Progress in neuro-psychopharmacology & biological psychiatry. 2024-01-12. PMID:38215930. |
the nucleus accumbens (nac) plays a crucial role in the brain's reward system, with the nucleus accumbens core (nacore) specifically implicated in compulsive drug seeking and relapse. |
2024-01-12 |
2024-01-15 |
rat |
| Timothy J Onofrychuk, Ashton L Heidt, Spencer N Orvold, Quentin Greba, John G Howlan. Nucleus accumbens core dopamine D2 receptors are required for performance of the odor span task in male rats. Psychopharmacology. 2024-01-06. PMID:38183429. |
while the role of the nac core in reward and effort-based decision making is well established, its role in working memory (wm) processes is incompletely understood. |
2024-01-06 |
2024-01-09 |
rat |