| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mathilde C C Guillaumin, Paulius Viskaitis, Eva Bracey, Denis Burdakov, Daria Peleg-Raibstei. Disentangling the role of NAc D1 and D2 cells in hedonic eating. Molecular psychiatry. 2023-07-04. PMID:37402855. |
here, we probed the roles of nac d1 and d2 cells in these processes using cell-specific recording and optogenetic manipulation in diverse behavioral paradigms that disentangle reward traits of 'liking' and 'wanting' related to food choice and overeating in healthy mice. |
2023-07-04 |
2023-08-14 |
mouse |
| Laura Santana Cordón, Domingo Afonso-Oramas, Alejandro Lemus Mesa, Miriam González-Gómez, Pedro Barroso-Chine. Morphological study of neuropeptide Y expression in human and mouse anterior insular cortex: overexpression in the insular cortex and nucleus accumbens in obese mice on a long-term obesogenic diet. Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft. 2023-06-24. PMID:37355144. |
brain reward circuits are altered in response to continued intake, in particular the dopaminergic projections from the ventral tegmental area (vta) to the nac. |
2023-06-24 |
2023-08-14 |
mouse |
| Federica Lucantonio, Shuwen Li, Jaden Lu, Jacob Roeglin, Leonardo Bontempi, Brenda C Shields, Carlos A Zarate, Michael R Tadross, Marco Pignatell. Ketamine rescues anhedonia by cell-type and input specific adaptations in the Nucleus Accumbens. bioRxiv : the preprint server for biology. 2023-06-19. PMID:37333325. |
here, we show that the nucleus accumbens (nac), a major hub of the reward circuitry, is essential for ketamine's effect in rescuing anhedonia in mice subjected to chronic stress, a critical risk factor in the genesis of depression in humans. |
2023-06-19 |
2023-08-14 |
mouse |
| David Levcik, Adam H Sugi, Marcelo Aguilar-Rivera, José A Pochapski, Gabriel Baltazar, Laura N Pulido, Cyrus Villas Boas, Romulo Fuentes-Flores, Saleem M Nicola, Claudio Da Cunh. Nucleus accumbens shell neurons encode the kinematics of reward approach locomotion. Neuroscience. 2023-06-17. PMID:37330195. |
the nucleus accumbens (nac) is considered an interface between motivation and action, with nac neurons playing an important role in promoting reward approach. |
2023-06-17 |
2023-08-14 |
rat |
| David Levcik, Adam H Sugi, Marcelo Aguilar-Rivera, José A Pochapski, Gabriel Baltazar, Laura N Pulido, Cyrus Villas Boas, Romulo Fuentes-Flores, Saleem M Nicola, Claudio Da Cunh. Nucleus accumbens shell neurons encode the kinematics of reward approach locomotion. Neuroscience. 2023-06-17. PMID:37330195. |
these findings suggest that these three classes of nac neurons influence the time course of speed changes during locomotor approach to reward. |
2023-06-17 |
2023-08-14 |
rat |
| Kyle D Ketchesin, Darius D Becker-Krail, Xiangning Xue, Rashaun S Wilson, TuKiet T Lam, Kenneth R Williams, Angus C Nairn, George C Tseng, Ryan W Loga. Differential Effects of Cocaine and Morphine on the Diurnal Regulation of the Mouse Nucleus Accumbens Proteome. Journal of proteome research. 2023-06-13. PMID:37311105. |
repeated use of substances such as psychostimulants and opioids may lead to significant alterations in molecular rhythms in the nucleus accumbens (nac), a brain region central to reward and motivation. |
2023-06-13 |
2023-08-14 |
mouse |
| Zhaosong Chu, Lijin Yuan, Mengxin He, Yuqi Cheng, Yi Lu, Xiufeng Xu, Zonglin She. Atrophy of bilateral nucleus accumbens in melancholic depression. Neuroreport. vol 34. issue 10. 2023-06-04. PMID:37270840. |
evidence from previous literature suggests that the nucleus accumbens (nac), hippocampus, and amygdala play critical roles in the reward circuit. |
2023-06-04 |
2023-08-14 |
human |
| Pengbo Jing, Qiang Sha. Exogenous oxytocin microinjection into the nucleus accumbens shell attenuates social dominance in group-housed male mice. Physiology & behavior. 2023-06-03. PMID:37270150. |
the nucleus accumbens (nac), a part of the brain's limbic system, is involved in a variety of brain functions, including reward motivation and social hierarchy. |
2023-06-03 |
2023-08-14 |
mouse |
| Ruijie Jin, Shanbin Sun, Yang Hu, Hongfei Zhang, Xiangrong Su. Neuropeptides Modulate Feeding via the Dopamine Reward Pathway. Neurochemical research. 2023-05-26. PMID:37233918. |
the reward system comprises the ventral tegmental area (vta), nucleus accumbens (nac), hypothalamus, and limbic system. |
2023-05-26 |
2023-08-14 |
Not clear |
| Ruijie Jin, Shanbin Sun, Yang Hu, Hongfei Zhang, Xiangrong Su. Neuropeptides Modulate Feeding via the Dopamine Reward Pathway. Neurochemical research. 2023-05-26. PMID:37233918. |
according to recent literature, neuropeptides released from the hypothalamus and other brain regions regulate reward feeding predominantly through dopaminergic neurons projecting from the vta to the nac. |
2023-05-26 |
2023-08-14 |
Not clear |
| Julianna Cavallaro, Jenna Yeisley, Başak Akdoǧan, Ronald E Salazar, Joseph R Floeder, Peter D Balsam, Eduardo F Gall. Dopamine D2 receptors in nucleus accumbens cholinergic interneurons increase impulsive choice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-05-23. PMID:37221325. |
here, we show that d2r upregulation in cins of the mouse nac increases impulsive choice as measured in a delay discounting task without affecting reward magnitude sensitivity or interval timing. |
2023-05-23 |
2023-08-14 |
mouse |
| Julia M Kirkland, Erin L Edgar, Ishan Patel, Ashley M Kope. Impaired microglia-mediated synaptic pruning in the nucleus accumbens during adolescence results in persistent dysregulation of familiar, but not novel social interactions in sex-specific ways. bioRxiv : the preprint server for biology. 2023-05-19. PMID:37205324. |
the nucleus accumbens (nac) is an intermediate reward relay center that develops during adolescence and mediates both social behaviors and dopaminergic signaling. |
2023-05-19 |
2023-08-14 |
human |
| J M Kirkland, Ishan Patel, Monali S Ardeshna, Ashley M Kope. Microglial synaptic pruning in the nucleus accumbens during adolescence sex-specifically influences splenic immune outcomes. bioRxiv : the preprint server for biology. 2023-05-19. PMID:37205376. |
we published that microglia-mediated synaptic pruning occurs in the nucleus accumbens (nac) reward region during adolescence to mediate social development in male and female rats. |
2023-05-19 |
2023-08-14 |
rat |
| J M Kirkland, Ishan Patel, Ashley M Kope. Microglia-mediated synaptic pruning in the nucleus accumbens during adolescence: A preliminary study of the proteomic consequences and putative female-specific pruning target. bioRxiv : the preprint server for biology. 2023-05-19. PMID:37205455. |
we published that microglia-c3-mediated synaptic pruning also occurs in the nucleus accumbens (nac) reward region during adolescence to mediate social development in male and female rats. |
2023-05-19 |
2023-08-14 |
rat |
| Cheng-Bo He, Yuan Jin, Yan Li, Qian Zhang, Bai Yang, Mang Xu, Juan Yang, Xi-Nan Yi, Yu-Lin Dong, Jian Wang, Yun-Qing L. Collateral projections from the ventral tegmental area/substantia nigra pars compacta to the nucleus accumbens and insular cortex in the rat. Anatomical science international. 2023-05-10. PMID:37160827. |
previous studies demonstrated that the vta/snc to nucleus accumbens (nac) pathway is critical in reward and motivation. |
2023-05-10 |
2023-08-14 |
rat |
| Cristina E Maria-Rios, Geoffrey G Murphy, Jonathan D Morro. Subregional Differences in Medium Spiny Neuron Intrinsic Excitability Properties between Nucleus Accumbens Core and Shell in Male Rats. eNeuro. 2023-05-08. PMID:37156609. |
the nucleus accumbens (nac) is known for its central role in reward and motivation (day and carelli, 2007; floresco, 2015; salgado and kaplitt, 2015). |
2023-05-08 |
2023-08-14 |
rat |
| Parth Bhatia, Lite Yang, Jay X J Luo, Mengyi Xu, William Rentha. Epigenomic profiling of mouse nucleus accumbens at single-cell resolution. Molecular and cellular neurosciences. 2023-05-03. PMID:37137383. |
the nucleus accumbens (nac) is a key brain region involved in reward processing and is linked to multiple neuropsychiatric conditions such as substance use disorder, depression, and chronic pain. |
2023-05-03 |
2023-08-14 |
mouse |
| Michał Sobstyl, Angelika Stapińska-Synie. Deep brain stimulation of the medial forebrain bundle for treatment-resistant depression - a narrative literature review. Postepy psychiatrii neurologii. vol 30. issue 3. 2023-04-21. PMID:37082768. |
the main nucleus of the reward circuit is the nucleus accumbens (nac), which plays a critical role in reward-seeking behavior, motivation, and addiction. |
2023-04-21 |
2023-08-14 |
Not clear |
| Zahra Ebrahimi, Nazanin Kahvandi, Elahe Shahriari, Alireza Komaki, Seyed Asaad Karimi, Marzieh Naderishahab, Maryam Sharifi, Abdolrahman Sarih. VU0155041, a positive allosteric modulator of mGluR4, in the nucleus accumbens facilitates extinction and inhibits the reinstatement of morphine-induced conditioned place preference in male rats. Brain research bulletin. 2023-03-30. PMID:36997034. |
nucleus accumbens (nac) neurons appear to be at the hub of the reward circuit. |
2023-03-30 |
2023-08-14 |
rat |
| Zahra Fatahi, Mohammad Fatahi, Mirmohammadali Mirramezani Alizamini, Ahmad Ghorbani, Mohammad Ismail Zibaii, Abbas Haghparas. Exogenous Cannabinoids Impair Effort-Related Decision-Making via Affecting Neural Synchronization between the Anterior Cingulate Cortex and Nucleus Accumbens. Brain sciences. vol 13. issue 3. 2023-03-29. PMID:36979223. |
in this study, neural synchronization and functional connectivity between the nac and acc while endeavor-related decision-making and reaching reward were evaluated. |
2023-03-29 |
2023-08-14 |
Not clear |