All Relations between risk-taking and medial prefrontal cortex

Publication Sentence Publish Date Extraction Date Species
Ate Bijlsma, Evelien E Birza, Tara C Pimentel, Janneke P M Maranus, Marieke J J M van Gaans, José G Lozeman-van T Klooster, Annemarie J M Baars, E J Marijke Achterberg, Heidi M B Lesscher, Corette J Wierenga, Louk J M J Vanderschure. Opportunities for risk-taking during play alters cognitive performance and prefrontal inhibitory signalling in rats of both sexes. The European journal of neuroscience. 2024-03-21. PMID:38511534. here, we tested in rats how opportunities for risk-taking during play affect the development of cognitive and emotional capacities and medial prefrontal cortex (mpfc) function, a brain structure important for risk-based decision making. 2024-03-21 2024-03-23 rat
Christy R Rogers, Virnaliz Jimenez, Amanda Benjamin, Karen D Rudolph, Eva H Telze. The Effect of Parents and Peers on the Neural Correlates of Risk Taking and Antisocial Behavior During Adolescence. Journal of youth and adolescence. 2023-05-30. PMID:37249810. high parent-adolescent closeness in early adolescence predicted lower antisocial behavior for girls in later adolescence via lower affiliation with deviant peer groups and less activation of the medial prefrontal cortex during risk taking. 2023-05-30 2023-08-14 Not clear
Chenyu Lv, Qiang Wang, Chuansheng Chen, Gui Xue, Qinghua H. Activation patterns of the dorsal medial prefrontal cortex and frontal pole predict individual differences in decision impulsivity. Brain imaging and behavior. vol 15. issue 1. 2021-04-27. PMID:32248386. the present study theorizes on and examines whether the activation patterns of the dorsal medial prefrontal cortex (dmpfc) and the frontal pole (fp) during the risk-taking "cups task", as captured in the scanner, can predict the delay discounting rate (k) based on an intertemporal decision task performed outside the scanner. 2021-04-27 2023-08-13 Not clear
Dana Lengel, Jimmy W Huh, Jessica R Barson, Ramesh Raghupath. Progesterone treatment following traumatic brain injury in the 11-day-old rat attenuates cognitive deficits and neuronal hyperexcitability in adolescence. Experimental neurology. vol 330. 2021-02-01. PMID:32335121. this was accompanied by an increase in intrinsic excitability and frequency of spontaneous excitatory post-synaptic currents (epscs), and a decrease in the frequency of spontaneous inhibitory post-synaptic currents in layer 2/3 neurons within the medial prefrontal cortex (pfc), a region that is implicated in both object recognition and risk-taking behaviors. 2021-02-01 2023-08-13 rat
Thiago Wendt Viola, Luis Eduardo Wearick-Silva, Kerstin C Creutzberg, Érika Kestering-Ferreira, Rodrigo Orso, Anderson Centeno-Silva, Lucas Albrechet-Souza, Paul R Marshall, Xiang Li, Timothy W Bredy, Marco A Riva, Rodrigo Grassi-Oliveir. Postnatal impoverished housing impairs adolescent risk-assessment and increases risk-taking: A sex-specific effect associated with histone epigenetic regulation of Crfr1 in the medial prefrontal cortex. Psychoneuroendocrinology. vol 99. 2019-05-31. PMID:30172072. postnatal impoverished housing impairs adolescent risk-assessment and increases risk-taking: a sex-specific effect associated with histone epigenetic regulation of crfr1 in the medial prefrontal cortex. 2019-05-31 2023-08-13 mouse
Jay V Deng, Caitlin A Orsini, Kristy G Shimp, Barry Setlo. MeCP2 Expression in a Rat Model of Risky Decision Making. Neuroscience. vol 369. 2019-02-18. PMID:29155278. in experiment 1, expression of mecp2 as assessed by immunoblotting in the medial prefrontal cortex (mpfc), but not the striatum, was inversely correlated with the degree of preference for the large, risky reward (risk taking) seven days after the last rdt test. 2019-02-18 2023-08-13 rat
Jing Yu, Rui Li, Yuhua Guo, Fang Fang, Suhuan Duan, Xu Le. Resting-State Functional Connectivity Within Medial Prefrontal Cortex Mediates Age Differences in Risk Taking. Developmental neuropsychology. vol 42. issue 3. 2017-12-12. PMID:28471240. resting-state functional connectivity within medial prefrontal cortex mediates age differences in risk taking. 2017-12-12 2023-08-13 human
Patricia Muñoz-Villegas, Verónica Mireya Rodríguez, Magda Giordano, Jorge Juáre. Risk-taking, locomotor activity and dopamine levels in the nucleus accumbens and medial prefrontal cortex in male rats treated prenatally with alcohol. Pharmacology, biochemistry, and behavior. vol 153. 2017-08-25. PMID:28011337. risk-taking, locomotor activity and dopamine levels in the nucleus accumbens and medial prefrontal cortex in male rats treated prenatally with alcohol. 2017-08-25 2023-08-13 rat
Victor Vorobyev, Myoung Soo Kwon, Dagfinn Moe, Riitta Parkkola, Heikki Hämäläine. Risk-Taking Behavior in a Computerized Driving Task: Brain Activation Correlates of Decision-Making, Outcome, and Peer Influence in Male Adolescents. PloS one. vol 10. issue 6. 2016-02-29. PMID:26052943. when groups were defined by actual task performance, risk-taking activated two areas in the left medial prefrontal cortex (pfc) significantly more in low than in high risk-takers. 2016-02-29 2023-08-13 human
Jianmin Zeng, Qinglin Zhang, Changming Chen, Rongjun Yu, Qiyong Gon. An fMRI study on sunk cost effect. Brain research. vol 1519. 2014-01-23. PMID:23665393. higher sunk cost only increased activity of some brain areas (mainly lateral frontal and parietal cortices, which are involved in risk-taking), whereas lower incremental cost mainly increased activity of some brain areas (including striatum and medial prefrontal cortex, which are sensitive to rewards). 2014-01-23 2023-08-12 human
Emily E Barkley-Levenson, Linda Van Leijenhorst, Adriana Galvá. Behavioral and neural correlates of loss aversion and risk avoidance in adolescents and adults. Developmental cognitive neuroscience. vol 3. 2013-06-12. PMID:23245222. during risk-seeking behavior, adolescent activation in medial prefrontal cortex (mpfc) was negatively correlated with self-reported likelihood of risk taking. 2013-06-12 2023-08-12 human
Nicholas W Simon, Karienn S Montgomery, Blanca S Beas, Marci R Mitchell, Candi L LaSarge, Ian A Mendez, Cristina Bañuelos, Colin M Vokes, Aaron B Taylor, Rebecca P Haberman, Jennifer L Bizon, Barry Setlo. Dopaminergic modulation of risky decision-making. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 48. 2012-02-09. PMID:22131407. d1 mrna expression in both nucleus accumbens shell and insular cortex was positively associated with risk-taking, while d2 mrna expression in orbitofrontal and medial prefrontal cortex predicted risk preference in opposing nonlinear patterns. 2012-02-09 2023-08-12 rat
Bernadette M Cortese, Todd R Mitchell, Matthew P Galloway, Kristen E Prevost, Jidong Fang, Gregory J Moore, Thomas W Uhd. Region-specific alteration in brain glutamate: possible relationship to risk-taking behavior. Physiology & behavior. vol 99. issue 4. 2010-05-12. PMID:20006966. an inverse relationship between glutamate in the medial prefrontal cortex and risk taking in the epm and a positive association between the ratio of glutamate in the hippocampus to medial prefrontal cortex and risk taking was revealed. 2010-05-12 2023-08-12 rat