| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Antón Barreiro-Iglesias, Verona Villar-Cerviño, Begoña Villar-Cheda, Ramón Anadón, María Celina Rodici. Neurochemical characterization of sea lamprey taste buds and afferent gustatory fibers: presence of serotonin, calretinin, and CGRP immunoreactivity in taste bud bi-ciliated cells of the earliest vertebrates. The Journal of comparative neurology. vol 511. issue 4. 2008-12-30. PMID:18831528. |
neurochemical characterization of sea lamprey taste buds and afferent gustatory fibers: presence of serotonin, calretinin, and cgrp immunoreactivity in taste bud bi-ciliated cells of the earliest vertebrates. |
2008-12-30 |
2023-08-12 |
Not clear |
| Antón Barreiro-Iglesias, Verona Villar-Cerviño, Begoña Villar-Cheda, Ramón Anadón, María Celina Rodici. Neurochemical characterization of sea lamprey taste buds and afferent gustatory fibers: presence of serotonin, calretinin, and CGRP immunoreactivity in taste bud bi-ciliated cells of the earliest vertebrates. The Journal of comparative neurology. vol 511. issue 4. 2008-12-30. PMID:18831528. |
neuroactive substances such as serotonin and other monoamines have been suggested to be involved in the transmission of gustatory signals from taste bud cells to afferent fibers. |
2008-12-30 |
2023-08-12 |
Not clear |
| Antón Barreiro-Iglesias, Verona Villar-Cerviño, Begoña Villar-Cheda, Ramón Anadón, María Celina Rodici. Neurochemical characterization of sea lamprey taste buds and afferent gustatory fibers: presence of serotonin, calretinin, and CGRP immunoreactivity in taste bud bi-ciliated cells of the earliest vertebrates. The Journal of comparative neurology. vol 511. issue 4. 2008-12-30. PMID:18831528. |
we used immunofluorescence methods with antibodies raised against serotonin, tyrosine hydroxylase (th), gamma-aminobutyric acid (gaba), glutamate, calcitonin gene-related peptide (cgrp), neuropeptide y (npy), calretinin, and acetylated alpha-tubulin to characterize the neurochemistry and innervation of taste buds in the sea lamprey, petromyzon marinus l. for localization of proliferative cells in taste buds we used bromodeoxyuridine labeling and proliferating cell nuclear antigen immunohistochemistry. |
2008-12-30 |
2023-08-12 |
Not clear |
| Antón Barreiro-Iglesias, Verona Villar-Cerviño, Begoña Villar-Cheda, Ramón Anadón, María Celina Rodici. Neurochemical characterization of sea lamprey taste buds and afferent gustatory fibers: presence of serotonin, calretinin, and CGRP immunoreactivity in taste bud bi-ciliated cells of the earliest vertebrates. The Journal of comparative neurology. vol 511. issue 4. 2008-12-30. PMID:18831528. |
this suggests that serotonin participates in the transmission of gustatory signals and indicates that this substance appeared early on in vertebrate evolution. |
2008-12-30 |
2023-08-12 |
Not clear |
| Yi-Jen Huang, Yutaka Maruyama, Kuo-Shyan Lu, Elizabeth Pereira, Stephen D Rope. Mouse taste buds release serotonin in response to taste stimuli. Chemical senses. vol 30 Suppl 1. 2008-10-01. PMID:15738184. |
mouse taste buds release serotonin in response to taste stimuli. |
2008-10-01 |
2023-08-12 |
mouse |
| Yijen A Huang, Yutaka Maruyama, Robert Stimac, Stephen D Rope. Presynaptic (Type III) cells in mouse taste buds sense sour (acid) taste. The Journal of physiology. vol 586. issue 12. 2008-08-21. PMID:18420705. |
using calcium imaging on single isolated taste cells and with biosensor cells to identify neurotransmitter release, we show that presynaptic (type iii) cells specifically respond to acid taste stimulation and release serotonin. |
2008-08-21 |
2023-08-12 |
mouse |
| Abdelghani El-Yassimi, Aziz Hichami, Philippe Besnard, Naim Akhtar Kha. Linoleic acid induces calcium signaling, Src kinase phosphorylation, and neurotransmitter release in mouse CD36-positive gustatory cells. The Journal of biological chemistry. vol 283. issue 19. 2008-06-17. PMID:18321850. |
these results altogether demonstrate that la binds to mouse cd36-positive gustatory cells, induces src-ptks phosphorylation, triggers calcium signaling, and evokes the release of 5-hydroxytryptamine and noradrenalin, which in turn may be implicated in the downstream signaling to the afferent nerve fibers, thus transmitting the output signal from taste buds to the central nervous system. |
2008-06-17 |
2023-08-12 |
mouse |
| Shinji Kataoka, Ruibiao Yang, Yoshiro Ishimaru, Hiroaki Matsunami, Jean Sévigny, John C Kinnamon, Thomas E Finge. The candidate sour taste receptor, PKD2L1, is expressed by type III taste cells in the mouse. Chemical senses. vol 33. issue 3. 2008-06-11. PMID:18156604. |
the pkd2l1-positive cells are immunoreactive for neural cell adhesion molecule, serotonin, pgp-9.5 (ubiquitin carboxy-terminal transferase), and chromogranin a, all of which are present in type iii taste cells. |
2008-06-11 |
2023-08-12 |
mouse |
| Melissa L Caras, Kimberly MacKenzie, Benjamin Rodwin, Donald B Kat. Investigating the motivational mechanism of altered saline consumption following 5-HT(1A) manipulation. Behavioral neuroscience. vol 122. issue 2. 2008-06-03. PMID:18410179. |
the precise role played by serotonin (5-ht) in taste--an issue of great interest given the involvement of serotonin in human sensory and eating disorders--is a matter of considerable debate, perhaps because of the variety of methodologies that have been brought to bear by different researchers. |
2008-06-03 |
2023-08-12 |
human |
| Takashi Suzuk. Cellular mechanisms in taste buds. The Bulletin of Tokyo Dental College. vol 48. issue 4. 2008-05-30. PMID:18360101. |
serotonin (5-ht) plays a role in cell-to-cell transmission of taste signals. |
2008-05-30 |
2023-08-12 |
human |
| Takashi Suzuk. Cellular mechanisms in taste buds. The Bulletin of Tokyo Dental College. vol 48. issue 4. 2008-05-30. PMID:18360101. |
findings on 5-ht and atp suggest that various different transmitters and receptors are present in taste buds. |
2008-05-30 |
2023-08-12 |
human |
| Gennady Dvoryanchikov, Seth M Tomchik, Nirupa Chaudhar. Biogenic amine synthesis and uptake in rodent taste buds. The Journal of comparative neurology. vol 505. issue 3. 2007-12-12. PMID:17879273. |
although adenosine triphosphate (atp) is known to be an afferent transmitter in the peripheral taste system, serotonin (5-ht) and norepinephrine (ne) have also been proposed as candidate neurotransmitters and have been detected immunocytochemically in mammalian taste cells. |
2007-12-12 |
2023-08-12 |
Not clear |
| Gennady Dvoryanchikov, Seth M Tomchik, Nirupa Chaudhar. Biogenic amine synthesis and uptake in rodent taste buds. The Journal of comparative neurology. vol 505. issue 3. 2007-12-12. PMID:17879273. |
to understand the significance of biogenic amines in taste, we evaluated the ability of taste cells to synthesize, transport, and package 5-ht and ne. |
2007-12-12 |
2023-08-12 |
Not clear |
| Gennady Dvoryanchikov, Seth M Tomchik, Nirupa Chaudhar. Biogenic amine synthesis and uptake in rodent taste buds. The Journal of comparative neurology. vol 505. issue 3. 2007-12-12. PMID:17879273. |
we show by reverse transcriptase-polymerase chain reaction and immunofluorescence microscopy that the enzymes for 5-ht synthesis, tryptophan hydroxylase (tph) and aromatic amino acid decarboxylase (aadc) are expressed in taste cells. |
2007-12-12 |
2023-08-12 |
Not clear |
| Gennady Dvoryanchikov, Seth M Tomchik, Nirupa Chaudhar. Biogenic amine synthesis and uptake in rodent taste buds. The Journal of comparative neurology. vol 505. issue 3. 2007-12-12. PMID:17879273. |
taste buds also robustly express plasma membrane transporters for 5-ht and ne. |
2007-12-12 |
2023-08-12 |
Not clear |
| Gennady Dvoryanchikov, Seth M Tomchik, Nirupa Chaudhar. Biogenic amine synthesis and uptake in rodent taste buds. The Journal of comparative neurology. vol 505. issue 3. 2007-12-12. PMID:17879273. |
in summary, we postulate that aminergic presynaptic taste cells synthesize only 5-ht, whereas ne (perhaps secreted by sympathetic fibers) may be concentrated and repackaged for secretion. |
2007-12-12 |
2023-08-12 |
Not clear |
| Stephen D Rope. Signal transduction and information processing in mammalian taste buds. Pflugers Archiv : European journal of physiology. vol 454. issue 5. 2007-11-13. PMID:17468883. |
once a taste signal is generated in a taste cell, the subsequent steps involve secretion of neurotransmitters, including atp and serotonin. |
2007-11-13 |
2023-08-12 |
Not clear |
| Stephen D Rope. Signal transduction and information processing in mammalian taste buds. Pflugers Archiv : European journal of physiology. vol 454. issue 5. 2007-11-13. PMID:17468883. |
in contrast, taste cells that do have synapses release serotonin in response to gustatory stimulation. |
2007-11-13 |
2023-08-12 |
Not clear |
| Stephen D Rope. Signal transduction and information processing in mammalian taste buds. Pflugers Archiv : European journal of physiology. vol 454. issue 5. 2007-11-13. PMID:17468883. |
finally, atp secreted from receptor cells also acts on neighboring taste cells to stimulate their release of serotonin. |
2007-11-13 |
2023-08-12 |
Not clear |
| Yi-Jen Huang, Yutaka Maruyama, Gennady Dvoryanchikov, Elizabeth Pereira, Nirupa Chaudhari, Stephen D Rope. The role of pannexin 1 hemichannels in ATP release and cell-cell communication in mouse taste buds. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 15. 2007-10-17. PMID:17389364. |
atp further stimulates other taste cells to release a second transmitter, serotonin. |
2007-10-17 |
2023-08-12 |
mouse |