| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| William A Goddard, Ravinder Abro. 3-Dimensional structures of G protein-coupled receptors and binding sites of agonists and antagonists. The Journal of nutrition. vol 137. issue 6 Suppl 1. 2007-08-06. PMID:17513420. |
these receptors play a critical role in cell communications (dopamine, histamine, epinephrine, and serotonin) and in sensing the outside world (vision, smell, taste, and pain). |
2007-08-06 |
2023-08-12 |
human |
| Yuji Seta, Shinji Kataoka, Takashi Toyono, Kuniaki Toyoshim. Immunohistochemical localization of aromatic L-amino acid decarboxylase in mouse taste buds and developing taste papillae. Histochemistry and cell biology. vol 127. issue 4. 2007-07-16. PMID:17211625. |
our results of double staining with aadc and taste cell markers indicate that only the type iii cells could convert 5-hydroxytryptophan (5-htp) to serotonin within taste buds. |
2007-07-16 |
2023-08-12 |
mouse |
| Takeshi Suwabe, Robert M Bradle. Effects of 5-hydroxytryptamine and substance P on neurons of the inferior salivatory nucleus. Journal of neurophysiology. vol 97. issue 4. 2007-07-10. PMID:17267757. |
these data show that 5-ht and sp excite most of the isn neurons innervating the lingual von ebner glands possibly modulating the synaptic drive to these neurons derived from afferent gustatory input. |
2007-07-10 |
2023-08-12 |
Not clear |
| Kate Sutherland, Richard L Young, Nicole J Cooper, Michael Horowitz, L Ashley Blacksha. Phenotypic characterization of taste cells of the mouse small intestine. American journal of physiology. Gastrointestinal and liver physiology. vol 292. issue 5. 2007-07-06. PMID:17290008. |
intestinal taste modalities may be signaled by these enteroendocrine cells via the release of 5-ht, glp-1, or coexpressed mediators or by brush cells via a nonnitrergic mediator in distinct regions of the intestine. |
2007-07-06 |
2023-08-12 |
mouse |
| Huazhi Ma, Ruibiao Yang, Stacey M Thomas, John C Kinnamo. Qualitative and quantitative differences between taste buds of the rat and mouse. BMC neuroscience. vol 8. 2007-02-13. PMID:17207280. |
in the present study we have used antisera directed against plcbeta2, alpha-gustducin, serotonin (5-ht), pgp 9.5 and synaptobrevin-2 to determine the percentages of taste cells expressing these markers in taste buds in both rodent species. |
2007-02-13 |
2023-08-12 |
mouse |
| Daniela Rüedi-Bettschen, Weining Zhang, Holger Russig, Boris Ferger, Anna Weston, Else-Marie Pedersen, Joram Feldon, Christopher R Pryc. Early deprivation leads to altered behavioural, autonomic and endocrine responses to environmental challenge in adult Fischer rats. The European journal of neuroscience. vol 24. issue 10. 2007-01-30. PMID:17156212. |
relative to nh and eh, which exhibited remarkably similar phenotypes, ed led, principally in males, to chronic traits of: reduced motivation for and consumption of gustatory reward; increased activity in the pre-test and test phases of the forced swim test; reduced coping behaviour in an aversive environment; attenuated plasma corticosterone stress response to a normal plasma acth stress response; increased hypertensive response to a novel environment; and increased prefrontal cortical serotonin. |
2007-01-30 |
2023-08-12 |
human |
| Tom P Heath, Jan K Melichar, David J Nutt, Lucy F Donaldso. Human taste thresholds are modulated by serotonin and noradrenaline. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 49. 2006-12-29. PMID:17151269. |
human taste thresholds are modulated by serotonin and noradrenaline. |
2006-12-29 |
2023-08-12 |
human |
| Tom P Heath, Jan K Melichar, David J Nutt, Lucy F Donaldso. Human taste thresholds are modulated by serotonin and noradrenaline. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 49. 2006-12-29. PMID:17151269. |
circumstances in which serotonin (5-ht) and noradrenaline (na) are altered, such as in anxiety or depression, are associated with taste disturbances, indicating the importance of these transmitters in the determination of taste thresholds in health and disease. |
2006-12-29 |
2023-08-12 |
human |
| Tom P Heath, Jan K Melichar, David J Nutt, Lucy F Donaldso. Human taste thresholds are modulated by serotonin and noradrenaline. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 49. 2006-12-29. PMID:17151269. |
measurement of taste function in healthy humans before and after a 5-ht reuptake inhibitor, na reuptake inhibitor, or placebo showed that enhancing 5-ht significantly reduced the sucrose taste threshold by 27% and the quinine taste threshold by 53%. |
2006-12-29 |
2023-08-12 |
human |
| Tom P Heath, Jan K Melichar, David J Nutt, Lucy F Donaldso. Human taste thresholds are modulated by serotonin and noradrenaline. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 49. 2006-12-29. PMID:17151269. |
we show that 5-ht and na participate in setting taste thresholds, that human taste in normal healthy subjects is plastic, and that modulation of these neurotransmitters has distinct effects on different taste modalities. |
2006-12-29 |
2023-08-12 |
human |
| Rafael Ortíz-Alvarado, Omar Guzmán-Quevedo, Rosalio Mercado-Camargo, Thomas Haertle, Caroline Vignes, Francisco Bolaños-Jiméne. Expression of tryptophan hydroxylase in developing mouse taste papillae. FEBS letters. vol 580. issue 22. 2006-11-09. PMID:16989820. |
these results point to the synthesis of 5-ht in gustatory papillae, and allow one to hypothesize that the development of taste buds might be modulated by serotonin. |
2006-11-09 |
2023-08-12 |
mouse |
| Petr Zach, Zach Petr, Jiri Krivanek, Krivanek Jiri, Karel Vales, Vales Kare. Serotonin and dopamine in the parabrachial nucleus of rats during conditioned taste aversion learning. Behavioural brain research. vol 170. issue 2. 2006-09-14. PMID:16603254. |
serotonin and dopamine in the parabrachial nucleus of rats during conditioned taste aversion learning. |
2006-09-14 |
2023-08-12 |
rat |
| Petr Zach, Zach Petr, Jiri Krivanek, Krivanek Jiri, Karel Vales, Vales Kare. Serotonin and dopamine in the parabrachial nucleus of rats during conditioned taste aversion learning. Behavioural brain research. vol 170. issue 2. 2006-09-14. PMID:16603254. |
a microdialysis technique was used to monitor changes in serotonin (5-ht), 5-hydroxyindole acetic acid (5-hiaa) and dopamine (da) in the extracellular space of the parabrachial nucleus (pbn) of rats to estimate the contribution of these neurotransmitter systems to the acquisition of conditioned taste aversion (cta). |
2006-09-14 |
2023-08-12 |
rat |
| S D Rope. Cell communication in taste buds. Cellular and molecular life sciences : CMLS. vol 63. issue 13. 2006-08-22. PMID:16732426. |
there is strong evidence that serotonin and atp play a role in cell-to-cell signaling and sensory output in the gustatory end organs. |
2006-08-22 |
2023-08-12 |
Not clear |
| Dianna L Bartel, Susan L Sullivan, Elise G Lavoie, Jean Sévigny, Thomas E Finge. Nucleoside triphosphate diphosphohydrolase-2 is the ecto-ATPase of type I cells in taste buds. The Journal of comparative neurology. vol 497. issue 1. 2006-07-26. PMID:16680780. |
to determine which of the three taste cell types expresses this enzyme, double-label assays were performed with antisera directed against the glial glutamate/aspartate transporter (glast), the transduction pathway proteins phospholipase cbeta2 (plcbeta2) or the g-protein subunit alpha-gustducin, and serotonin (5ht) as markers of type i, ii, and iii taste cells, respectively. |
2006-07-26 |
2023-08-12 |
mouse |
| Kevin B Freeman, Kenner C Rice, Anthony L Rile. Assessment of monoamine transporter inhibition in the mediation of cocaine-induced conditioned taste aversion. Pharmacology, biochemistry, and behavior. vol 82. issue 3. 2006-03-02. PMID:16337262. |
using the conditioned taste aversion (cta) preparation, the present study examined the role of monoamine uptake inhibition in cocaine's aversive effects by comparing cocaine to three reuptake inhibitors with relative specificity for the transporters of dopamine (dat; gbr 12909), norepinephrine (net; desipramine) and serotonin (sert; clomipramine). |
2006-03-02 |
2023-08-12 |
rat |
| Ellen A Walker, Stephen J Kohut, Richard W Hass, Edward K Brown, Anupama Prabandham, Timothy Lefeve. Selective and nonselective serotonin antagonists block the aversive stimulus properties of MK212 and m-chlorophenylpiperazine (mCPP) in mice. Neuropharmacology. vol 49. issue 8. 2006-01-17. PMID:16165167. |
in the present study, the capacities of two 5-ht(2c) agonists, mk212 and mcpp, to produce conditioned taste aversions in mice were evaluated. |
2006-01-17 |
2023-08-12 |
mouse |
| Ellen A Walker, Stephen J Kohut, Richard W Hass, Edward K Brown, Anupama Prabandham, Timothy Lefeve. Selective and nonselective serotonin antagonists block the aversive stimulus properties of MK212 and m-chlorophenylpiperazine (mCPP) in mice. Neuropharmacology. vol 49. issue 8. 2006-01-17. PMID:16165167. |
acquisition of conditioned taste aversions was blocked by nonselective serotonin antagonists cyproheptadine, bromo-lsd, metergoline, methysergide and mianserin. |
2006-01-17 |
2023-08-12 |
mouse |
| Ellen A Walker, Stephen J Kohut, Richard W Hass, Edward K Brown, Anupama Prabandham, Timothy Lefeve. Selective and nonselective serotonin antagonists block the aversive stimulus properties of MK212 and m-chlorophenylpiperazine (mCPP) in mice. Neuropharmacology. vol 49. issue 8. 2006-01-17. PMID:16165167. |
selective 5-ht(2b/2c) antagonist sb206,553 blocked both mk212- and mcpp-induced conditioned taste aversion although selective 5-ht(2b/2c) antagonist sb200,646 only blocked mcpp-induced conditioned taste aversion. |
2006-01-17 |
2023-08-12 |
mouse |
| Ellen A Walker, Stephen J Kohut, Richard W Hass, Edward K Brown, Anupama Prabandham, Timothy Lefeve. Selective and nonselective serotonin antagonists block the aversive stimulus properties of MK212 and m-chlorophenylpiperazine (mCPP) in mice. Neuropharmacology. vol 49. issue 8. 2006-01-17. PMID:16165167. |
taken together, these data indicate that the serotonin agonists mk212 and mcpp produce conditioned taste aversion and that these effects are mediated predominantly through 5-ht(2c) receptors. |
2006-01-17 |
2023-08-12 |
mouse |