| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Stefan K Maier, Hannes Hahne, Amin Moghaddas Gholami, Benjamin Balluff, Stephan Meding, Cédrik Schoene, Axel K Walch, Bernhard Kuste. Comprehensive identification of proteins from MALDI imaging. Molecular & cellular proteomics : MCP. vol 12. issue 10. 2014-05-09. PMID:23782541. |
we introduce a generic method that removes this issue by systematically identifying the proteins embedded in the maldi matrix using a combination of bottom-up and top-down proteomics. |
2014-05-09 |
2023-08-12 |
human |
| Stefan K Maier, Hannes Hahne, Amin Moghaddas Gholami, Benjamin Balluff, Stephan Meding, Cédrik Schoene, Axel K Walch, Bernhard Kuste. Comprehensive identification of proteins from MALDI imaging. Molecular & cellular proteomics : MCP. vol 12. issue 10. 2014-05-09. PMID:23782541. |
top-down analysis of the matrix proteome identified 124 mostly n- and c-terminally fragmented proteins indicating considerable protein processing activity in tissues. |
2014-05-09 |
2023-08-12 |
human |
| Gobind Das, Manohar Chirumamilla, Andrea Toma, Anisha Gopalakrishnan, Remo Proietti Zaccaria, Alessandro Alabastri, Marco Leoncini, Enzo Di Fabrizi. Plasmon based biosensor for distinguishing different peptides mutation states. Scientific reports. vol 3. 2014-02-26. PMID:23652645. |
periodic and reproducible gold nanocuboids with various matrix dimensions and with different inter-particle gaps were fabricated by means of top-down technique. |
2014-02-26 |
2023-08-12 |
Not clear |
| James W Reinhardt, Daniel A Krakauer, Keith J Gooc. Complex matrix remodeling and durotaxis can emerge from simple rules for cell-matrix interaction in agent-based models. Journal of biomechanical engineering. vol 135. issue 7. 2014-01-21. PMID:23722647. |
using a top-down approach, an agent-based model was developed within netlogo where cells and extracellular matrix (ecm) fibers were composed of multiple agents to create deformable structures capable of exerting, reacting to, and transmitting mechanical force. |
2014-01-21 |
2023-08-12 |
Not clear |
| Alessandra Pinna, Barbara Lasio, Massimo Piccinini, Benedetta Marmiroli, Heinz Amenitsch, Paolo Falcaro, Yasuaki Tokudome, Luca Malfatti, Plinio Innocenz. Combining top-down and bottom-up routes for fabrication of mesoporous titania films containing ceria nanoparticles for free radical scavenging. ACS applied materials & interfaces. vol 5. issue 8. 2013-10-25. PMID:23484882. |
nanocomposite thin films formed by mesoporous titania layers loaded with ceria nanoparticles have been obtained by combining bottom-up self-assembly synthesis of a titania matrix with top-down hard x-ray lithography of nanocrystalline cerium oxide. |
2013-10-25 |
2023-08-12 |
Not clear |
| Tingli Lu, Yuhui Li, Tao Che. Techniques for fabrication and construction of three-dimensional scaffolds for tissue engineering. International journal of nanomedicine. vol 8. 2013-09-16. PMID:23345979. |
in the conventional "top-down" approach, cells are seeded onto a biocompatible and biodegradable scaffold, in which cells are expected to populate in the scaffold and create their own extracellular matrix. |
2013-09-16 |
2023-08-12 |
Not clear |
| Chima O Oluigbo, Asem Salma, Ali R Reza. Targeting the affective and cognitive aspects of chronic neuropathic pain using basal forebrain neuromodulation: rationale, review and proposal. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 19. issue 9. 2012-12-27. PMID:22771143. |
we have reviewed the limitations of the present treatment strategies for chronic pain, neurophysiology of somatosensory transmission and nociception, mechanisms of neuropathic pain, the concept of a "pain matrix" and the "top-down" modulation of pain, and the cognitive affective role in processing of the pain experience. |
2012-12-27 |
2023-08-12 |
Not clear |
| Giovanni D'Andrea, Antonello D'Arrigo, Maurizio Dalle Carbonare, Alberta Leo. Pathogenesis of migraine: role of neuromodulators. Headache. vol 52. issue 7. 2012-11-27. PMID:22671857. |
in view of this, we propose that migraine attacks derive from a top-down dysfunctional process that initiates in the frontal lobe in a hyperexcitable and hypoenergetic brain, thereafter progressing downstream resulting in abnormally activated nuclei of the pain matrix. |
2012-11-27 |
2023-08-12 |
Not clear |
| M-Marsel Mesula. Attentional and confusional States. Continuum (Minneapolis, Minn.). vol 16. issue 4 Behavioral Neurology. 2012-10-02. PMID:22810518. |
focal lesions that interfere with the bottom-up or top-down regulation of attention, or multifocal partial lesions that interrupt multiple domain-specific processing pathways, can disrupt the attentional matrix and give rise to the acute confusional state syndrome. |
2012-10-02 |
2023-08-12 |
Not clear |
| Francesco Urciuolo, Giorgia Imparato, Angela Guaccio, Benedetto Mele, Paolo A Nett. Novel strategies to engineering biological tissue in vitro. Methods in molecular biology (Clifton, N.J.). vol 811. 2012-02-21. PMID:22042683. |
in top-down approaches, the cells are expected to populate the scaffold and create the appropriate extracellular matrix and microarchitecture often with the aid of a bioreactor that furnish the set of stimuli required for an optimal cellular viability. |
2012-02-21 |
2023-08-12 |
Not clear |
| Franz-Georg Hanisc. Top-down sequencing of O-glycoproteins by in-source decay matrix-assisted laser desorption ionization mass spectrometry for glycosylation site analysis. Analytical chemistry. vol 83. issue 12. 2011-11-09. PMID:21526855. |
the top-down sequencing on the protein level by maldi-ms is based on the in-source decay (isd) of intact glycoproteins induced by hydrogen radical transfer from the matrix. |
2011-11-09 |
2023-08-12 |
human |
| G D'Andrea, A Leo. Pathogenesis of migraine: from neurotransmitters to neuromodulators and beyond. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 31 Suppl 1. 2010-08-17. PMID:20464574. |
we believe that migraine attacks derive from a top-down dysfunctional process that initiates in a hyperexcitable and hypoenergetic brain in the frontal lobe and downstream in abnormally activated nuclei of the pain matrix. |
2010-08-17 |
2023-08-12 |
Not clear |
| Jonathan M Borku. Chronic headaches and the neurobiology of somatization. Current pain and headache reports. vol 14. issue 1. 2010-07-21. PMID:20425215. |
underlying mechanisms may include encoding of similar experiences (eg, depression, loss, pain-distress) in overlapping patterns of activation, failure of common regulatory mechanisms, direct top-down activation of the pain matrix, and changes in descending pain facilitatory and inhibitory tone. |
2010-07-21 |
2023-08-12 |
Not clear |
| Jiro Kurat. [A potential role of functional magnetic resonance imaging in the diagnosis of pain]. Masui. The Japanese journal of anesthesiology. vol 58. issue 11. 2009-12-29. PMID:19928501. |
the top-down component of pain matrix also explains basic neuroimaging findings on the anticipation, empathy, and placebo effects of pain, and on the cortical trigger of the descending pain inhibitory system. |
2009-12-29 |
2023-08-12 |
Not clear |
| Christopher A Brown, Ben Seymour, Wael El-Deredy, Anthony K P Jone. Confidence in beliefs about pain predicts expectancy effects on pain perception and anticipatory processing in right anterior insula. Pain. vol 139. issue 2. 2009-01-13. PMID:18584963. |
we hypothesized that confidence is associated with anticipatory activation of areas of the pain matrix involved with top-down modulation of pain. |
2009-01-13 |
2023-08-12 |
human |
| Loïc Quinton, Kevin Demeure, Rowan Dobson, Nicolas Gilles, Valérie Gabelica, Edwin De Pau. New method for characterizing highly disulfide-bridged peptides in complex mixtures: application to toxin identification from crude venoms. Journal of proteome research. vol 6. issue 8. 2008-09-26. PMID:17580849. |
this work presents an lc-maldi approach allowing (1) a rapid classification of toxins according to their number of disulfide bonds and (2) a rapid top-down sequencing of the toxins using a new maldi matrix enhancing in-source decay (isd). |
2008-09-26 |
2023-08-12 |
Not clear |
| Kevin Demeure, Loïc Quinton, Valérie Gabelica, Edwin De Pau. Rational selection of the optimum MALDI matrix for top-down proteomics by in-source decay. Analytical chemistry. vol 79. issue 22. 2008-01-07. PMID:17939742. |
rational selection of the optimum maldi matrix for top-down proteomics by in-source decay. |
2008-01-07 |
2023-08-12 |
Not clear |
| Julie Hardoui. Protein sequence information by matrix-assisted laser desorption/ionization in-source decay mass spectrometry. Mass spectrometry reviews. vol 26. issue 5. 2007-10-19. PMID:17492750. |
the in-source decay (isd) occurring in a matrix assisted laser desorption/ionization (maldi) source appears an interesting analytical tool to obtain n-terminal sequence, to identify proteins and to characterize ptms by a "top-down" strategy. |
2007-10-19 |
2023-08-12 |
Not clear |
| Peng Pan, Scott A McLucke. Electrospray ionization of protein mixtures at low pH. Analytical chemistry. vol 75. issue 6. 2003-10-10. PMID:12659214. |
protein matrix effects in electrospray ionization are particularly relevant to the development of top-down protein identification methodologies involving protein mixtures, whereby whole protein ions are subjected to tandem mass spectrometry. |
2003-10-10 |
2023-08-12 |
Not clear |