| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shuang Ding, Zhuowei Shi, Kaiping Huang, Xiao Fan, Xiujuan Li, Helin Zheng, Longlun Wang, Zichun Yan, Jinhua Ca. Aberrant white matter microstructure detected by automatic fiber quantification in pediatric myelin oligodendrocyte glycoprotein antibody-associated disease. Multiple sclerosis and related disorders. vol 84. 2024-02-14. PMID:38354445. |
myelin oligodendrocyte glycoprotein antibody-associated diseases (mogad) is an idiopathic inflammatory demyelinating disorder in children, for which the precise damage patterns of the white matter (wm) fibers remain unclear. |
2024-02-14 |
2024-02-17 |
Not clear |
| Minji Bang, Yul Heo, Tai Kiu Choi, Sang-Hyuk Le. Positive Effects of Uric Acid on White Matter Microstructures and Treatment Response in Patients With Schizophrenia. Schizophrenia bulletin. 2024-02-01. PMID:38300803. |
oxidative stress is a key factor causing wm damage by hindering oligodendrocyte development and myelin maturation. |
2024-02-01 |
2024-02-04 |
Not clear |
| Takahiro Shimizu, Stuart G Nayar, Matthew Swire, Yi Jiang, Matthew Grist, Malte Kaller, Cassandra Sampaio Baptista, David M Bannerman, Heidi Johansen-Berg, Katsutoshi Ogasawara, Koujiro Tohyama, Huiliang Li, William D Richardso. Oligodendrocyte dynamics dictate cognitive performance outcomes of working memory training in mice. Nature communications. vol 14. issue 1. 2023-10-14. PMID:37838794. |
oligodendrocyte dynamics dictate cognitive performance outcomes of working memory training in mice. |
2023-10-14 |
2023-11-08 |
mouse |
| Costanza Ferrari Bardile, Carola I Radulescu, Mahmoud A Poulad. Oligodendrocyte pathology in Huntington's disease: from mechanisms to therapeutics. Trends in molecular medicine. 2023-08-17. PMID:37591764. |
white matter (wm) structures, representing myelin-rich regions of the brain, are profoundly affected in hd, and recent findings reveal oligodendroglia dysfunction as an early pathological event. |
2023-08-17 |
2023-09-07 |
Not clear |
| Huiyang Wang, Yueyang Liu, Zhenkun Guo, Minghui Cui, Peng Pang, Jingyu Yang, Chunfu W. Enhancement of oligodendrocyte autophagy alleviates white matter injury and cognitive impairment induced by chronic cerebral hypoperfusion in rats. Acta pharmaceutica Sinica. B. vol 13. issue 5. 2023-05-30. PMID:37250159. |
by the 14th day, abnormal accumulation of autophagy substrate, lysosomal dysfunction, and the activation of mechanistic target of rapamycin (mtor) pathway were observed in wm, paralleled with mature oligodendrocyte death. |
2023-05-30 |
2023-08-14 |
rat |
| Tania Campos-Ordoñez, Susana González-Granero, Marielena Eudave-Patiño, Jonathan Buriticá, Vicente Herranz-Pérez, José M García-Verdugo, Oscar Gonzalez-Pere. Normal pressure hydrocephalus decreases the proliferation of oligodendrocyte progenitor cells and the expression of CNPase and MOG proteins in the corpus callosum before behavioral deficits occur. Experimental neurology. 2023-04-19. PMID:37075967. |
this study aims to determine whether 60- or 120-day nph disrupts the cytoarchitecture and functioning of white matter (wm) and oligodendrocyte precursor cells (opcs) and establish whether these changes are reversible after hydrocephalus treatment. |
2023-04-19 |
2023-08-14 |
mouse |
| Shiji Deng, Shu Shu, Lili Zhai, Shengnan Xia, Xiang Cao, Huiya Li, Xinyu Bao, Pinyi Liu, Yun X. Optogenetic Stimulation of mPFC Alleviates White Matter Injury-Related Cognitive Decline after Chronic Ischemia through Adaptive Myelination. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2022-12-19. PMID:36529961. |
here, bilateral carotid artery stenosis (bcas) is used to model ischemic wmi-related cognitive impairment and uncover that optogenetic and chemogenetic activation of glutamatergic neurons in the medial prefrontal cortex (mpfc) promote the differentiation of oligodendrocyte precursor cells (opcs) in the corpus callosum, leading to improvements in myelin repair and working memory. |
2022-12-19 |
2023-08-14 |
Not clear |
| Markus M Hilscher, Christoffer Mattsson Langseth, Petra Kukanja, Chika Yokota, Mats Nilsson, Gonçalo Castelo-Branc. Spatial and temporal heterogeneity in the lineage progression of fine oligodendrocyte subtypes. BMC biology. vol 20. issue 1. 2022-05-24. PMID:35610641. |
here, we apply in situ sequencing (iss) to simultaneously probe the expression of 124 marker genes of distinct oligodendrocyte populations, providing comprehensive maps of the corpus callosum, cingulate, motor, and somatosensory cortex in the brain, as well as gray matter (gm) and white matter (wm) regions in the spinal cord, at postnatal (p10), juvenile (p20), and young adult (p60) stages. |
2022-05-24 |
2023-08-13 |
Not clear |
| Kang Peng, Sravanthi Koduri, Fenghui Ye, Jinting Yang, Richard F Keep, Guohua Xi, Ya Hu. A timeline of oligodendrocyte death and proliferation following experimental subarachnoid hemorrhage. CNS neuroscience & therapeutics. 2022-02-12. PMID:35150055. |
this study investigates temporal changes in the corpus callosum (cc), including wm edema and oligodendrocyte death after sah, and the role of lipocalin-2 (lcn2) in those changes. |
2022-02-12 |
2023-08-13 |
Not clear |
| I Ferrer, P Andrés-Benit. White matter alterations in Alzheimer's disease without concomitant pathologies. Neuropathology and applied neurobiology. vol 46. issue 7. 2021-10-28. PMID:32255227. |
this study analyses oligodendrocyte and myelin markers in the frontal wm in a series of ad cases without clinical or pathological co-morbidities. |
2021-10-28 |
2023-08-13 |
Not clear |
| Dongdong Liu, Yushu Dong, Gen Li, Zheng Zou, Guangzhi Hao, Hua Feng, Pengyu Pan, Guobiao Lian. Melatonin Attenuates White Matter Injury via Reducing Oligodendrocyte Apoptosis After Subarachnoid Hemorrhage in Mice. Turkish neurosurgery. vol 30. issue 5. 2021-06-28. PMID:32705666. |
to determine whether melatonin (mlt) mitigates white matter (wm) injury by attenuating nod-like receptor family pyrin domain-containing 3 (nlrp3)-associated oligodendrocyte apoptosis after subarachnoid hemorrhage (sah). |
2021-06-28 |
2023-08-13 |
mouse |
| Isidro Ferrer, Pol Andrés-Benito, Maria Victoria Zelaya, Maria Elena Erro Aguirre, Margarita Carmona, Karina Ausín, Mercedes Lachén-Montes, Joaquín Fernández-Irigoyen, Enrique Santamaría, José Antonio Del Ri. Familial globular glial tauopathy linked to MAPT mutations: molecular neuropathology and seeding capacity of a prototypical mixed neuronal and glial tauopathy. Acta neuropathologica. vol 139. issue 4. 2021-05-17. PMID:31907603. |
globular glial tauopathy (ggt) is a progressive neurodegenerative disease involving the grey matter and white matter (wm) and characterized by neuronal deposition of hyper-phosphorylated, abnormally conformed, truncated, oligomeric 4rtau in neurons and in glial cells forming typical globular astrocyte and oligodendrocyte inclusions (gais and gois, respectively) and coiled bodies. |
2021-05-17 |
2023-08-13 |
mouse |
| Isidro Ferrer, Pol Andrés-Benito, Maria Victoria Zelaya, Maria Elena Erro Aguirre, Margarita Carmona, Karina Ausín, Mercedes Lachén-Montes, Joaquín Fernández-Irigoyen, Enrique Santamaría, José Antonio Del Ri. Familial globular glial tauopathy linked to MAPT mutations: molecular neuropathology and seeding capacity of a prototypical mixed neuronal and glial tauopathy. Acta neuropathologica. vol 139. issue 4. 2021-05-17. PMID:31907603. |
expression of oligodendrocyte markers olig1 and olig2mrna, and myelin-related genes mbp, plp1, cnp, mag, mal, mog, and mobp are significantly decreased in wm; cnpase, plp1, and mbp antibodies reveal reduction and disruption of myelinated fibres; and smi31 antibodies mark axonal damage in the wm. |
2021-05-17 |
2023-08-13 |
mouse |
| Andra L Dingman, Krista M Rodgers, Robert M Dietz, Sean P Hickey, Alexandra P Frazier, Amy C Clevenger, Joan C Yonchek, Richard J Traystman, Wendy B Macklin, Paco S Herso. Oligodendrocyte Progenitor Cell Proliferation and Fate after White Matter Stroke in Juvenile and Adult Mice. Developmental neuroscience. 2020-10-30. PMID:30861520. |
we utilized a model of focal ischemic wm injury to determine the oligodendrocyte (ol) response to focal wm ischemic injury in juvenile and adult mice. |
2020-10-30 |
2023-08-13 |
mouse |
| Ming Tong, Howard Gonzalez-Navarrete, Tyler Kirchberg, Billy Gotama, Emine B Yalcin, Jared Kay, Suzanne M de la Mont. Ethanol-Induced White Matter Atrophy Is Associated with Impaired Expression of Aspartyl-Asparaginyl- Journal of drug and alcohol research. vol 6. 2020-10-01. PMID:29204305. |
ethanol-induced white matter atrophy is associated with impaired expression of aspartyl-asparaginyl- alcohol-induced white matter (wm) degeneration is linked to cognitive-motor deficits and impairs insulin/insulin-like growth factor (igf) and notch networks regulating oligodendrocyte function. |
2020-10-01 |
2023-08-13 |
Not clear |
| José J Miguel-Hidalg. Molecular Neuropathology of Astrocytes and Oligodendrocytes in Alcohol Use Disorders. Frontiers in molecular neuroscience. vol 11. 2020-09-30. PMID:29615864. |
in addition, alcoholism alters the expression of astrocyte and myelin proteins and of oligodendrocyte transcription factors important for the maintenance and plasticity of myelin sheaths in wm and gm. |
2020-09-30 |
2023-08-13 |
human |
| Siren Tønnesen, Tobias Kaufmann, Nhat Trung Doan, Dag Alnæs, Aldo Córdova-Palomera, Dennis van der Meer, Jaroslav Rokicki, Torgeir Moberget, Tiril P Gurholt, Unn K Haukvik, Torill Ueland, Trine Vik Lagerberg, Ingrid Agartz, Ole A Andreassen, Lars T Westly. White matter aberrations and age-related trajectories in patients with schizophrenia and bipolar disorder revealed by diffusion tensor imaging. Scientific reports. vol 8. issue 1. 2019-11-14. PMID:30237410. |
supported by histological and genetic evidence implicating myelin, neuroinflammation and oligodendrocyte dysfunction in schizophrenia spectrum disorders (sz), diffusion tensor imaging (dti) studies have consistently shown white matter (wm) abnormalities when compared to healthy controls (hc). |
2019-11-14 |
2023-08-13 |
Not clear |
| Shubei Ma, Jianyi Wang, Yanling Wang, Xuejiao Dai, Fei Xu, Xuguang Gao, Joycelyne Johnson, Na Xu, Rehana K Leak, Xiaoming Hu, Yumin Luo, Jun Che. Diabetes Mellitus Impairs White Matter Repair and Long-Term Functional Deficits After Cerebral Ischemia. Stroke. vol 49. issue 10. 2019-09-10. PMID:30355111. |
high glucose concentrations may shift microglia/macrophage polarization toward a proinflammatory phenotype, significantly impairing oligodendrocyte precursor cell differentiation and wm repair. |
2019-09-10 |
2023-08-13 |
mouse |
| Prakasham Rumajogee, Svetlana Altamentova, Lijun Li, Junyi Li, Jian Wang, Alan Kuurstra, Mohamad Khazaei, Stephanie Beldick, Ravi S Menon, Derek van der Kooy, Michael G Fehling. Exogenous Neural Precursor Cell Transplantation Results in Structural and Functional Recovery in a Hypoxic-Ischemic Hemiplegic Mouse Model. eNeuro. vol 5. issue 5. 2019-04-19. PMID:30713997. |
a regular pathobiological hallmark of cp is oligodendrocyte maturation impairment resulting in white matter (wm) injury and reduced axonal myelination. |
2019-04-19 |
2023-08-13 |
mouse |
| Demetra P Kelenis, Emma Hart, Morgan Edwards-Fligner, Jane E Johnson, Tou Yia Vu. ASCL1 regulates proliferation of NG2-glia in the embryonic and adult spinal cord. Glia. vol 66. issue 9. 2019-02-12. PMID:29683222. |
long-term clonal lineage analysis reveals that the progeny of single ascl1+ oligodendrocyte progenitors (olps) and ng2-glia are primarily restricted to the gm or wm, even though they undergo extensive proliferation to give rise to large clusters of ols in the postnatal spinal cord. |
2019-02-12 |
2023-08-13 |
Not clear |