| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jin Ri Hong, Hyunah Choo, Ghilsoo Na. Neuropathic pain-alleviating effects of pyrazole-conjugated arylsulfonamides as 5-HT Bioorganic & medicinal chemistry letters. vol 27. issue 17. 2017-09-13. PMID:28729057. |
neuropathic pain-alleviating effects of pyrazole-conjugated arylsulfonamides as 5-ht a novel series of arylsulfonylaminomethyl-3-(1-phenyl-5-isopropyl)pyrazoles was evaluated for serotonin receptor subtype 6 (5-ht |
2017-09-13 |
2023-08-13 |
Not clear |
| Guangchen Ji, Wei Zhang, Lenin Mahimainathan, Madhusudhanan Narasimhan, Takaki Kiritoshi, Xiuzhen Fan, Jigong Wang, Thomas A Green, Volker Neugebaue. 5-HT The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 6. 2017-07-27. PMID:28011743. |
the cea receives excitatory and inhibitory inputs from the basolateral nucleus (bla) and serotonin receptor subtype 5-ht |
2017-07-27 |
2023-08-13 |
Not clear |
| Jemma L Trick, Sivapalan Chelvaniththilan, Gianni Klesse, Prafulla Aryal, E Jayne Wallace, Stephen J Tucker, Mark S P Sanso. Functional Annotation of Ion Channel Structures by Molecular Simulation. Structure (London, England : 1993). vol 24. issue 12. 2017-06-28. PMID:27866853. |
using the serotonin receptor (5-ht |
2017-06-28 |
2023-08-13 |
Not clear |
| Nick J Spencer, Damien J Keatin. Is There a Role for Endogenous 5-HT in Gastrointestinal Motility? How Recent Studies Have Changed Our Understanding. Advances in experimental medicine and biology. vol 891. 2017-06-20. PMID:27379639. |
then, perhaps one of the most startling of all observations was the discovery that selective 5-ht receptor antagonists actually have the same inhibitory effects on peristalsis and the migrating complex in segments of intestine that had been depleted of all endogenous 5-ht. |
2017-06-20 |
2023-08-13 |
Not clear |
| Fayrouz El Maddah, Stefan Kehraus, Mamona Nazir, Celso Almeida, Gabriele M Köni. Insights into the Biosynthetic Origin of 3-(3-Furyl)alanine in Stachylidium sp. 293 K04 Tetrapeptides. Journal of natural products. vol 79. issue 11. 2017-06-09. PMID:27786475. |
293 k04 produces the n-methylated peptides endolide a (1) and endolide b (2), showing affinity for the vasopressin receptor 1a and serotonin receptor 5ht |
2017-06-09 |
2023-08-13 |
Not clear |
| Daniel Wacker, Sheng Wang, John D McCorvy, Robin M Betz, A J Venkatakrishnan, Anat Levit, Katherine Lansu, Zachary L Schools, Tao Che, David E Nichols, Brian K Shoichet, Ron O Dror, Bryan L Rot. Crystal Structure of an LSD-Bound Human Serotonin Receptor. Cell. vol 168. issue 3. 2017-05-29. PMID:28129538. |
the prototypical hallucinogen lsd acts via serotonin receptors, and here we describe the crystal structure of lsd in complex with the human serotonin receptor 5-ht |
2017-05-29 |
2023-08-13 |
human |
| M Wierucka-Rybak, M Wolak, M Juszczak, J Drobnik, E Bojanowsk. The inhibitory effect of combination treatment with leptin and cannabinoid CB1 receptor agonist on food intake and body weight gain is mediated by serotonin 1B and 2C receptors. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 67. issue 3. 2017-05-09. PMID:27512006. |
to investigate whether serotonin interacts with leptin and endocannabinoids to affect food intake and body weight, we administered 5-hydroxytryptamine(ht)1b and 5-hydroxytryptamine(ht)2c serotonin receptor antagonists (3 mg/kg gr 127935 and 0.5 mg/kg sb 242084, respectively) to male wistar rats treated simultaneously with leptin (100 μg/kg) and the cb1 receptor inverse agonist am 251 (1 mg/kg) for 3 days. |
2017-05-09 |
2023-08-13 |
rat |
| Takeshi Tsuruta, Shinichi Saito, Yosuke Osaki, Akihiro Hamada, Ayako Aoki-Yoshida, Kei Sonoyam. Organoids as an ex vivo model for studying the serotonin system in the murine small intestine and colon epithelium. Biochemical and biophysical research communications. vol 474. issue 1. 2017-05-08. PMID:27105910. |
reverse transcription-polymerase chain reaction (rt-pcr) analysis showed that small intestinal and colonic organoids express mrnas encoding tryptophan hydroxylase-1 (tph1) (the rate-limiting enzyme of 5-ht synthesis), serotonin reuptake transporter (sert), 5-ht receptor (htr)2a, htr2b, and htr4. |
2017-05-08 |
2023-08-13 |
Not clear |
| Imane Moutkine, Emily Quentin, Bruno P Guiard, Luc Maroteaux, Stephane Dol. Heterodimers of serotonin receptor subtypes 2 are driven by 5-HT The Journal of biological chemistry. vol 292. issue 15. 2017-04-28. PMID:28258217. |
heterodimers of serotonin receptor subtypes 2 are driven by 5-ht the serotonin receptor subtypes 2 comprise 5-ht |
2017-04-28 |
2023-08-13 |
Not clear |
| Nilgun Gurbuz, Mehmet Resit Asoglu, Ahmed A Ashour, Salama Salama, Gokhan S Kilic, Bulent Ozpola. A selective serotonin 5-HT European journal of obstetrics, gynecology, and reproductive biology. vol 206. 2017-04-20. PMID:27669395. |
in this study, we investigated the impact of serotonin receptor 5-ht |
2017-04-20 |
2023-08-13 |
Not clear |
| Zhong-Min Wu, Li-Hua Yang, Rong Cui, Gui-Lian Ni, Feng-Tian Wu, Yong Lian. Contribution of Hippocampal 5-HT Cellular and molecular neurobiology. vol 37. issue 4. 2017-04-17. PMID:27324798. |
while certain 5-ht receptor subtypes are likely critical for the symptoms of ptsd, few studies have examined the role of 5-ht |
2017-04-17 |
2023-08-13 |
Not clear |
| Yasuhiro Nakamura, Kazue Ise, Yuto Yamazaki, Fumiyoshi Fujishima, Keely M McNamara, Hironobu Sasan. Serotonin receptor 4 (5-hydroxytryptamine receptor Type 4) regulates expression of estrogen receptor beta and cell migration in hormone-naive prostate cancer. Indian journal of pathology & microbiology. vol 60. issue 1. 2017-03-13. PMID:28195088. |
among these, increased expression of serotonin receptor especially that of 5-hydroxytryptamine receptor type 4 (5-htr4) has been recently proposed to be involved in autocrine/paracrine mechanisms of castration-resistant prostate cancer, but the presence and clinical significance of 5-htr4 in hormone-naive prostate cancer (hnpc) and its interaction with hormonal signaling pathways have remained virtually unknown. |
2017-03-13 |
2023-08-13 |
Not clear |
| Cigdem Selli, Metiner Tosu. Effects of cyclopiazonic acid and dexamethasone on serotonin-induced calcium responses in vascular smooth muscle cells. Journal of physiology and biochemistry. vol 72. issue 2. 2017-03-06. PMID:26944908. |
furthermore, 5-ht receptor antagonist methysergide partially inhibited cpa-potentiated 5-ht contractions. |
2017-03-06 |
2023-08-13 |
rat |
| X G Zhang, H Zhang, X L Liang, Q Liu, H Y Wang, B Cao, J Cao, S Liu, Y J Long, W Y Xie, D Z Pen. Epigenetic mechanism of maternal post-traumatic stress disorder in delayed rat offspring development: dysregulation of methylation and gene expression. Genetics and molecular research : GMR. vol 15. issue 3. 2017-02-27. PMID:27706597. |
enzyme-linked immunosorbent assays showed that serotonin receptor (5-ht) and dopamine levels were significantly lower in ptsd offsprings than in control offsprings. |
2017-02-27 |
2023-08-13 |
rat |
| Guiqin Xie, Wanhong Zuo, Liangzhi Wu, Wenting Li, Wei Wu, Alex Bekker, Jiang-Hong Y. Serotonin modulates glutamatergic transmission to neurons in the lateral habenula. Scientific reports. vol 6. 2017-02-17. PMID:27033153. |
type 2 and 3 serotonin receptor antagonists attenuated serotonin's potentiation. |
2017-02-17 |
2023-08-13 |
rat |
| Jasmine Siew Min Chia, Ahmad Akira Omar Farouk, Azam Shah Mohamad, Mohd Roslan Sulaiman, Enoch Kumar Perima. Zerumbone alleviates chronic constriction injury-induced allodynia and hyperalgesia through serotonin 5-HT receptors. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 83. 2017-02-06. PMID:27570173. |
further investigation with 5-ht receptor antagonists methiothepin (5-ht |
2017-02-06 |
2023-08-13 |
mouse |
| Jo Sourbron, Henning Schneider, Angéla Kecskés, Yusu Liu, Ellen M Buening, Lieven Lagae, Ilse Smolders, Peter de Witt. Serotonergic Modulation as Effective Treatment for Dravet Syndrome in a Zebrafish Mutant Model. ACS chemical neuroscience. vol 7. issue 5. 2017-01-27. PMID:26822114. |
in a clinical study, add-on treatment with fenfluramine, a potent 5-hydroxytryptamine (5-ht) releaser activating multiple 5-ht receptor subtypes, made 70% of ds children seizure free. |
2017-01-27 |
2023-08-13 |
human |
| Peter J Gagolewicz, Hans C Dringenber. Age-Dependent Switch of the Role of Serotonergic 5-HT1A Receptors in Gating Long-Term Potentiation in Rat Visual Cortex In Vivo. Neural plasticity. vol 2016. 2016-12-30. PMID:27247804. |
while 5-ht application (0.1-10 mm) itself did not alter ltp levels, the broad-acting 5-ht receptor antagonists methiothepin (1 mm) resulted in a clear facilitation of ltp in adult animals, an effect that was mimicked by the selective 5-ht1a receptor antagonist way 100635 (1 mm). |
2016-12-30 |
2023-08-13 |
rat |
| C L Muller, A M J Anacker, J Veenstra-VanderWeel. The serotonin system in autism spectrum disorder: From biomarker to animal models. Neuroscience. vol 321. 2016-12-13. PMID:26577932. |
a knock-in mouse model of one of these variants, sert gly56ala, recapitulates the hyperserotonemia biomarker and shows increased brain serotonin clearance, increased serotonin receptor sensitivity, and altered social, communication, and repetitive behaviors. |
2016-12-13 |
2023-08-13 |
mouse |
| Ryo Hotta, Lily Cheng, Hannah K Graham, Nandor Nagy, Jaime Belkind-Gerson, George Mattheolabakis, Mansoor M Amiji, Allan M Goldstei. Delivery of enteric neural progenitors with 5-HT4 agonist-loaded nanoparticles and thermosensitive hydrogel enhances cell proliferation and differentiation following transplantation in vivo. Biomaterials. vol 88. 2016-12-13. PMID:26922325. |
since serotonin (5-ht) promotes enteric neuronal growth during embryonic development, we hypothesized that serotonin receptor agonism would augment growth of neurons from transplanted enscs. |
2016-12-13 |
2023-08-13 |
mouse |