| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jacob Sutton, Jeff Stroup, Mo So. Linezolid-induced serotonin toxicity in a patient not taking monoamine oxidase inhibitors or serotonin receptor antagonists. Proceedings (Baylor University. Medical Center). vol 29. issue 2. 2016-04-01. PMID:27034576. |
linezolid-induced serotonin toxicity in a patient not taking monoamine oxidase inhibitors or serotonin receptor antagonists. |
2016-04-01 |
2023-08-13 |
Not clear |
| Wenjing Law, Leah M Wuescher, Amanda Ortega, Vera M Hapiak, Patricia R Komuniecki, Richard Komunieck. Heterologous Expression in Remodeled C. elegans: A Platform for Monoaminergic Agonist Identification and Anthelmintic Screening. PLoS pathogens. vol 11. issue 4. 2016-03-29. PMID:25928899. |
specifically, 5-ht paralyzed c. elegans 5-ht receptor null animals expressing either nematode, insect or human orthologues of a key gαo-coupled 5-ht1-like receptor in the cholinergic motor neurons. |
2016-03-29 |
2023-08-13 |
human |
| Gordon F Buchanan, Haleigh R Smith, Amanda MacAskill, George B Richerso. 5-HT2A receptor activation is necessary for CO2-induced arousal. Journal of neurophysiology. vol 114. issue 1. 2016-03-28. PMID:25925320. |
these data identify the 5-ht(2a) receptor as an important mediator of co2-induced arousal and suggest that, while 5-ht neurons can be independently activated to drive co2-induced arousal, in the absence of 5-ht neurons and endogenous 5-ht, 5-ht receptor activation can act in a permissive fashion to facilitate co2-induced arousal via another as yet unidentified chemosensor system. |
2016-03-28 |
2023-08-13 |
mouse |
| Ross D Hoehn, David Nichols, Hartmut Neven, Sabre Kai. Neuroreceptor activation by vibration-assisted tunneling. Scientific reports. vol 5. 2016-02-29. PMID:25909758. |
we found that non-endogenous agonists of the serotonin receptor share a particular iet spectral aspect both amongst each other and with the serotonin molecule: a peak whose intensity scales with the known agonist potencies. |
2016-02-29 |
2023-08-13 |
Not clear |
| H Lefebvre, C Duparc, G Prévost, M C Zennaro, J Bertherat, E Louise. Paracrine control of steroidogenesis by serotonin in adrenocortical neoplasms. Molecular and cellular endocrinology. vol 408. 2016-02-08. PMID:25433205. |
in the human adrenal gland, 5-ht, released by subcapsular mast cells, stimulates corticosteroid production through a paracrine mode of communication which involves 5-ht receptor type 4 (5-ht4) primarily located in zona glomerulosa. |
2016-02-08 |
2023-08-13 |
human |
| John D McCorvy, Bryan L Rot. Structure and function of serotonin G protein-coupled receptors. Pharmacology & therapeutics. vol 150. 2016-02-08. PMID:25601315. |
the first serotonin crystal structures not only provide the first evidence of serotonin receptor topography but also provide mechanistic explanations into functional selectivity or biased agonism. |
2016-02-08 |
2023-08-13 |
Not clear |
| Yasuyuki Nakamura, Jun Ishii, Akihiko Kond. Applications of yeast-based signaling sensor for characterization of antagonist and analysis of site-directed mutants of the human serotonin 1A receptor. Biotechnology and bioengineering. vol 112. issue 9. 2016-01-20. PMID:25850571. |
the monoamine neurotransmitter serotonin (5-ht) regulates a wide spectrum of human physiology through the 5-ht receptor family. |
2016-01-20 |
2023-08-13 |
human |
| Scott F Leiser, Hillary Miller, Ryan Rossner, Marissa Fletcher, Alison Leonard, Melissa Primitivo, Nicholas Rintala, Fresnida J Ramos, Dana L Miller, Matt Kaeberlei. Cell nonautonomous activation of flavin-containing monooxygenase promotes longevity and health span. Science (New York, N.Y.). vol 350. issue 6266. 2016-01-12. PMID:26586189. |
this prolongevity signal requires the serotonin biosynthetic enzyme tph-1 in neurons and the serotonin receptor ser-7 in the intestine. |
2016-01-12 |
2023-08-13 |
mouse |
| Haritha Durairaj, Michael D Steury, Narayanan Parameswara. Paroxetine differentially modulates LPS-induced TNFα and IL-6 production in mouse macrophages. International immunopharmacology. vol 25. issue 2. 2016-01-04. PMID:25744603. |
to determine if the effects of paroxetine are mediated via modulation of the 5-ht system, we treated macrophages with 5-ht or 5-ht receptor antagonist (ly215840) in the presence of lps and/or paroxetine. |
2016-01-04 |
2023-08-13 |
mouse |
| Jimena Laporta, Kimberly P Keil, Chad M Vezina, Laura L Hernande. Peripheral serotonin regulates maternal calcium trafficking in mammary epithelial cells during lactation in mice. PloS one. vol 9. issue 10. 2015-12-28. PMID:25299122. |
mammary expression of serotonin receptor isoform 2b and its downstream pathways (plcβ3, pkc and map-erk1/2) are also decreased by serotonin deficiency, which might explain the numerous phenotypic alterations described above. |
2015-12-28 |
2023-08-13 |
mouse |
| J Laporta, L L Hernande. Serotonin receptor expression is dynamic in the liver during the transition period in Holstein dairy cows. Domestic animal endocrinology. vol 51. 2015-11-24. PMID:25528206. |
here, we explore circulating patterns of 5-ht and characterize the hepatic 5-ht receptor and glucose transporter profiles around calving in multiparous holstein dairy cows (n = 6, average lactation = 4 ± 1.9). |
2015-11-24 |
2023-08-13 |
cattle |
| M Gertrude Gutierrez, Noah Malmstad. Human serotonin receptor 5-HT(1A) preferentially segregates to the liquid disordered phase in synthetic lipid bilayers. Journal of the American Chemical Society. vol 136. issue 39. 2015-10-28. PMID:25211019. |
human serotonin receptor 5-ht(1a) preferentially segregates to the liquid disordered phase in synthetic lipid bilayers. |
2015-10-28 |
2023-08-13 |
human |
| Michael Aschermann, Pavel Jans. [Drug therapy of pulmonary arterial hypertension in 2014]. Vnitrni lekarstvi. vol 60. issue 4. 2015-10-26. PMID:24985985. |
anti-inflammatory agents: inhibitor of elastase, antagonist of b cells, immunosuppressive agents, inhibitor of hdac1; 3. agents affecting metabolism: nitrites, ppar antagonists, antioxidants, serotonin receptor antagonist and serotonin transporter blockers, statins, inhibitors of rho-kinase; 4. apoptosis inductors of smooth muscle cells: tyrosine-kinase inhibitors, elastase inhibitors; 5. agents influencing vascular regeneration: apelin, treatment targeted to endothelial cells, replacement of bmpr2. |
2015-10-26 |
2023-08-13 |
Not clear |
| Y Yu, D-Q Cao, H-Y Xu, M Sun, Z-L Huang, W-H Yung, N Lu, Y Huan. 5-HT3A receptors are required in long-term depression and AMPA receptor internalization. Neuroscience. vol 278. 2015-10-20. PMID:25130560. |
5-hydroxytrytamine (serotonin) type 3a receptors (5-ht3ars), as the only ligand-gated ion channels in the serotonin receptor family, are known to regulate neuronal excitation and release of gaba in hippocampal interneurons. |
2015-10-20 |
2023-08-13 |
mouse |
| Vaibhav P Pai, Laura L Hernandez, Malinda A Stull, Nelson D Horsema. The type 7 serotonin receptor, 5-HT 7 , is essential in the mammary gland for regulation of mammary epithelial structure and function. BioMed research international. vol 2015. 2015-10-12. PMID:25664318. |
the type 7 serotonin receptor, 5-ht 7 , is essential in the mammary gland for regulation of mammary epithelial structure and function. |
2015-10-12 |
2023-08-13 |
mouse |
| Natascha Nebel, Simone Maschauer, Amelie L Bartuschat, Stefanie K Fehler, Harald Hübner, Peter Gmeiner, Torsten Kuwert, Markus R Heinrich, Olaf Prante, Carsten Hock. Synthesis and evaluation of fluoro substituted pyridinylcarboxamides and their phenylazo analogues for potential dopamine D3 receptor PET imaging. Bioorganic & medicinal chemistry letters. vol 24. issue 23. 2015-10-06. PMID:25453796. |
they also exhibit considerable selectivity over the other dopamine receptor subtypes and noteworthy selectivity over the structurally related serotonin receptor subtypes 5-ht(1a) and 5-ht₂, offering potential radiotracers for positron emission tomography. |
2015-10-06 |
2023-08-13 |
Not clear |
| Sahar Mohammadi, Habibolah Khazaie, Ziba Rahimi, Asad Vaisi-Raygani, Newsha Zargooshi, Zohreh Rahim. The serotonin transporter (5-HTTLPR) but not serotonin receptor (5-HT2C Cys23Ser) variant is associated with bipolar I disorder in Kurdish population from Western Iran. Neuroscience letters. vol 590. 2015-09-14. PMID:25596490. |
the serotonin transporter (5-httlpr) but not serotonin receptor (5-ht2c cys23ser) variant is associated with bipolar i disorder in kurdish population from western iran. |
2015-09-14 |
2023-08-13 |
Not clear |
| Francisco García-Oscos, Oswaldo Torres-Ramírez, Lu Dinh, Luis Galindo-Charles, Elsy Arlene Pérez Padilla, Juan Carlos Pineda, Marco Atzori, Humberto Salgad. Activation of 5-HT receptors inhibits GABAergic transmission by pre-and post-synaptic mechanisms in layer II/III of the juvenile rat auditory cortex. Synapse (New York, N.Y.). vol 69. issue 3. 2015-09-10. PMID:25482075. |
to determine which the serotonin receptors were involved in this effect, we studied the influence of specific 5-ht receptor agonists and antagonists on ɣ-aminobutyric acid (gaba)ergic synaptic transmission. |
2015-09-10 |
2023-08-13 |
rat |
| Elizabeth P Baue. Serotonin in fear conditioning processes. Behavioural brain research. vol 277. 2015-09-08. PMID:25078294. |
the serotonergic system can be manipulated by administering serotonin receptor agonists and antagonists, as well as selective serotonin reuptake inhibitors (ssris), and these can have significant effects on emotional learning and memory. |
2015-09-08 |
2023-08-13 |
Not clear |
| Ashish Dhir, Jayrajsinh Sarvaiy. The efficacy of vortioxetine for the treatment of major depressive disorder. Expert review of neurotherapeutics. vol 14. issue 12. 2015-09-01. PMID:25418918. |
these mechanisms include property to inhibit serotonin reuptake via inhibiting serotonin transporters and acting on multiple serotonin receptor subtypes. |
2015-09-01 |
2023-08-13 |
Not clear |