| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marlene S William. Platelets and depression in cardiovascular disease: A brief review of the current literature. World journal of psychiatry. vol 2. issue 6. 2014-06-24. PMID:24175177. |
to date studies show increased serotonin response, increased platelet serotonin receptor density, decreased serotonin transporter binding, and decreased platelet serotonin levels in individuals with depression. |
2014-06-24 |
2023-08-12 |
Not clear |
| Susana Aznar, Anders B Klei. Regulating prefrontal cortex activation: an emerging role for the 5-HT₂A serotonin receptor in the modulation of emotion-based actions? Molecular neurobiology. vol 48. issue 3. 2014-06-18. PMID:23696058. |
recent animal and human functional magnetic resonance studies have pointed to a specific involvement of the 5-hydroxytryptamine (5-ht)2a serotonin receptor in the pfc feedback regulatory projection onto the amygdala. |
2014-06-18 |
2023-08-12 |
human |
| Manfred Göther. Serotonin discovery and stepwise disclosure of 5-HT receptor complexity over four decades. Part I. General background and discovery of serotonin as a basis for 5-HT receptor identification. Pharmacological reports : PR. vol 65. issue 4. 2014-06-13. PMID:24145072. |
serotonin discovery and stepwise disclosure of 5-ht receptor complexity over four decades. |
2014-06-13 |
2023-08-12 |
dog |
| Manfred Göther. Serotonin discovery and stepwise disclosure of 5-HT receptor complexity over four decades. Part I. General background and discovery of serotonin as a basis for 5-HT receptor identification. Pharmacological reports : PR. vol 65. issue 4. 2014-06-13. PMID:24145072. |
general background and discovery of serotonin as a basis for 5-ht receptor identification. |
2014-06-13 |
2023-08-12 |
dog |
| Jan E Lim, Cosima S Porteus, Nicholas J Bernie. Serotonin directly stimulates cortisol secretion from the interrenals in goldfish. General and comparative endocrinology. vol 192. 2014-06-10. PMID:24013027. |
thus, in goldfish, 5-ht can directly stimulate cortisol secretion from the interrenals via multiple 5-ht receptor subtypes and the chromaffin cells may be involved in the paracrine regulation of cortisol secretion via 5-ht. |
2014-06-10 |
2023-08-12 |
Not clear |
| Nathalie M Goodfellow, Derya Sargin, Mark S Ansorge, Jay A Gingrich, Evelyn K Lamb. Mice with compromised 5-HTT function lack phosphotyrosine-mediated inhibitory control over prefrontal 5-HT responses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 17. 2014-06-09. PMID:24760870. |
here, we found and characterized a deregulation of prefrontal 5-ht receptor electrophysiological signaling in mouse models of disrupted serotonin transporter (5-htt) function, a risk factor for emotional and cognitive disturbances. |
2014-06-09 |
2023-08-13 |
mouse |
| Hanne D Hansen, Matthias M Herth, Anders Ettrup, Valdemar L Andersen, Szabolcs Lehel, Agnete Dyssegaard, Jesper L Kristensen, Gitte M Knudse. Radiosynthesis and in vivo evaluation of novel radioligands for PET imaging of cerebral 5-HT7 receptors. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 55. issue 4. 2014-06-02. PMID:24566002. |
the serotonin (5-hydroxytryptamine [5-ΗΤ]) 7 receptor (5-ht7r) is the most recently discovered 5-ht receptor, and its physiologic and possible pathophysiologic roles are not fully elucidated. |
2014-06-02 |
2023-08-12 |
Not clear |
| Enza Lacivita, Paola De Giorgio, Daniela Patarnello, Mauro Niso, Nicola A Colabufo, Francesco Berardi, Roberto Perrone, Grzegorz Satala, Beata Duszynska, Andrzej J Bojarski, Marcello Leopold. Towards metabolically stable 5-HT7 receptor ligands: a study on 1-arylpiperazine derivatives and related isosters. Experimental brain research. vol 230. issue 4. 2014-05-27. PMID:23571499. |
serotonin 7 (5-hydroxytryptamine7 or 5-ht7) is the most recently identified serotonin receptor. |
2014-05-27 |
2023-08-12 |
human |
| Silvia Franzellitti, Sara Buratti, Marco Capolupo, Bowen Du, Samuel P Haddad, C Kevin Chambliss, Bryan W Brooks, Elena Fabbr. An exploratory investigation of various modes of action and potential adverse outcomes of fluoxetine in marine mussels. Aquatic toxicology (Amsterdam, Netherlands). vol 151. 2014-05-22. PMID:24361074. |
because fx acts as a selective serotonin (5-ht) re-uptake inhibitor increasing serotonergic neurotransmission at mammalian synapses, cell signaling alterations triggered by 5-ht receptor occupations were assessed. |
2014-05-22 |
2023-08-12 |
Not clear |
| Georgina de Foubert, Ahmad A Khundakar, Tyra S Zetterströ. Effects of repeated 5-HT₆ receptor stimulation on BDNF gene expression and cell survival. Neuroscience letters. vol 553. 2014-05-08. PMID:23981663. |
regarding 5-ht active drugs, the 5-ht receptor behind these effects remains unidentified. |
2014-05-08 |
2023-08-12 |
Not clear |
| Takahiro Kato, Seiji Kajiyama, Hiroshi Hamada, Masashi Kawamot. Long-term administration of fluvoxamine attenuates neuropathic pain and involvement of spinal serotonin receptors in diabetic model rats. Hiroshima journal of medical sciences. vol 62. issue 4. 2014-05-06. PMID:24597211. |
in addition, the involvement of spinal serotonin (5-ht) receptors in long-term fluvoxamine treatment was studied by intrathecal administration of 5-ht receptor antagonists. |
2014-05-06 |
2023-08-12 |
rat |
| Charles P Mercado, Maritza V Quintero, Yicong Li, Preeti Singh, Alicia K Byrd, Krajang Talabnin, Mayumi Ishihara, Parastoo Azadi, Nancy J Rusch, Balagurunathan Kuberan, Luc Maroteaux, Fusun Kili. A serotonin-induced N-glycan switch regulates platelet aggregation. Scientific reports. vol 3. 2014-04-28. PMID:24077408. |
the highest level of neu5gc was observed in platelets of 5-ht-infused, 5-ht transporter-knock out mice, suggesting that the surface delineated 5-ht receptor on platelets may promote cmah catalytic activity. |
2014-04-28 |
2023-08-12 |
mouse |
| Florent Viguier, Benoît Michot, Michel Hamon, Sylvie Bourgoi. Multiple roles of serotonin in pain control mechanisms--implications of 5-HT₇ and other 5-HT receptor types. European journal of pharmacology. vol 716. issue 1-3. 2014-04-24. PMID:23500207. |
multiple roles of serotonin in pain control mechanisms--implications of 5-ht₇ and other 5-ht receptor types. |
2014-04-24 |
2023-08-12 |
rat |
| Florent Viguier, Benoît Michot, Michel Hamon, Sylvie Bourgoi. Multiple roles of serotonin in pain control mechanisms--implications of 5-HT₇ and other 5-HT receptor types. European journal of pharmacology. vol 716. issue 1-3. 2014-04-24. PMID:23500207. |
the discovery of multiple 5-ht receptor subtypes allowed possible explanations to this dual action at the periphery versus the central nervous system (cns) since both excitatory and inhibitory effects can be exerted through 5-ht activation of different 5-ht receptors. |
2014-04-24 |
2023-08-12 |
rat |
| Niki Antypa, Alessandro Serretti, Dan Rujesc. Serotonergic genes and suicide: a systematic review. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 10. 2014-04-24. PMID:23742855. |
in this paper, we review evidence from studies examining the association between various serotonergic genes (tryptophan hydroxylase genes: tph1; tph2, serotonin transporter gene: 5-httlpr in slc6a4, serotonin receptor genes: htr1a, htr2a, htr1b, htr2c and monoamine oxidase a gene: maoa) and suicidal behavior. |
2014-04-24 |
2023-08-12 |
Not clear |
| Alan L Pehrson, Thomas Cremers, Cecile Bétry, Marieke G C van der Hart, Laerke Jørgensen, Mathias Madsen, Nasser Haddjeri, Bjarke Ebert, Connie Sanche. Lu AA21004, a novel multimodal antidepressant, produces regionally selective increases of multiple neurotransmitters--a rat microdialysis and electrophysiology study. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 2. 2014-04-21. PMID:22612991. |
preclinical research suggests that 5-ht receptor subtypes, including 5-ht1a, 5-ht1b, 5-ht3, and 5-ht7 receptors as well as the 5-ht transporter (sert), may have important roles in treating depression. |
2014-04-21 |
2023-08-12 |
rat |
| Marie E Gibbs, Leif Hert. Serotonin mediation of early memory formation via 5-HT2B receptor-induced glycogenolysis in the day-old chick. Frontiers in pharmacology. vol 5. 2014-04-18. PMID:24744730. |
the non-selective 5-ht receptor antagonist methiothepin and the selective 5-ht2b/c receptor antagonist sb221284 both inhibited memory, suggesting actions of serotonin on at least two different receptor subtypes. |
2014-04-18 |
2023-08-13 |
chicken |
| Kwangmi Ki. Neuroimmunological mechanism of pruritus in atopic dermatitis focused on the role of serotonin. Biomolecules & therapeutics. vol 20. issue 6. 2014-04-15. PMID:24009842. |
it is still questionable whether these serotonergic drugs exert the immunosuppressive effects via serotonin receptor or serotonin transporter. |
2014-04-15 |
2023-08-12 |
human |
| M S Hoffman, G S Mitchel. Spinal 5-HT7 receptors and protein kinase A constrain intermittent hypoxia-induced phrenic long-term facilitation. Neuroscience. vol 250. 2014-04-04. PMID:23850591. |
since serotonin released near phrenic motor neurons may activate multiple serotonin receptor subtypes, we tested the hypothesis that 5-ht7 receptor activation contributes to aih-induced pltf. |
2014-04-04 |
2023-08-12 |
rat |
| Janardhan P Bhattarai, Juan Roa, Allan E Herbison, Seong Kyu Ha. Serotonin acts through 5-HT1 and 5-HT2 receptors to exert biphasic actions on GnRH neuron excitability in the mouse. Endocrinology. vol 155. issue 2. 2014-03-20. PMID:24265447. |
studies using 5-ht receptor antagonists demonstrated that the activation of 5-ht(1a) receptors mediated the inhibitory responses, whereas the excitation was mediated by the activation of 5-ht(2a) receptors. |
2014-03-20 |
2023-08-12 |
mouse |