| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Elena V Mitroshina, Ekaterina A Marasanova, Maria V Vedunov. Functional Dimerization of Serotonin Receptors: Role in Health and Depressive Disorders. International journal of molecular sciences. vol 24. issue 22. 2023-11-25. PMID:38003611. |
the objective of this review is to consolidate the current understanding of interactions within the 5-ht receptor family and between 5-ht receptors and members of other receptor families. |
2023-11-25 |
2023-11-28 |
Not clear |
| Philip J Cowe. SSRIs in the Treatment of Depression: A Pharmacological CUL-DE-SAC? Current topics in behavioral neurosciences. 2023-11-03. PMID:37922101. |
attempts to supplement serotonin reuptake activity with actions at serotonin receptor sub-types have not yet yielded substantial benefits; however, vortioxetine may provide more utility in the management of cognitive impairment. |
2023-11-03 |
2023-11-08 |
Not clear |
| Qiyi You, Qijun Li, Liyuan Lv, Zhihua Lin, Yinghui Dong, Hanhan Ya. Genome-Wide Identification of 5-HT Receptor Gene Family in Razor Clam Animals : an open access journal from MDPI. vol 13. issue 20. 2023-10-30. PMID:37893932. |
genome-wide identification of 5-ht receptor gene family in razor clam serotonin (5-ht) is primarily distributed in the gastrointestinal and central nervous systems, where it plays a crucial role in regulating various physiological functions such as digestion, reproduction and establishing animal emotions. |
2023-10-30 |
2023-11-08 |
Not clear |
| Dhamyaa Abed Najm Al-Halboosi, Olena Savchenko, Lora K Heisler, Sergiy Sylantye. Modulation of GABA release by 5-HT Neuropharmacology. 2023-10-12. PMID:37827445. |
agonists of the 1b subtype of metabotropic serotonin receptor (5-ht |
2023-10-12 |
2023-10-15 |
Not clear |
| Apeksha Parajulee, Kuglae Ki. Structural studies of serotonin receptor family. BMB reports. 2023-10-11. PMID:37817438. |
understanding the structure, functions and pharmacology of the serotonin receptor family is essential for unraveling the complexities of serotonin signaling and developing targeted therapeutics for neuropsychiatric disorders. |
2023-10-11 |
2023-10-15 |
Not clear |
| Michael Hrabak, Connor Moon, Carlos A Bolaños-Guzmán, Heinz Steine. Vilazodone, a Selective Serotonin Reuptake Inhibitor with Diminished Impact on Methylphenidate-Induced Gene Regulation in the Striatum: Role of 5-HT1A Receptor. Molecular neurobiology. 2023-10-08. PMID:37807008. |
vilazodone differs from prototypical ssris in that, in addition to blocking serotonin reuptake, it acts as a partial agonist at the 5-ht1a serotonin receptor subtype. |
2023-10-08 |
2023-10-15 |
rat |
| Daisuke Kondo, Ruriko Suzuki, Ayako Matsumura, Hitomi Meguri, Masahiko Tanaka, Makoto Itakura, Naohide Hirashim. Methiothepin downregulates SNAP-23 and inhibits degranulation of rat basophilic leukemia cells and mouse bone marrow-derived mast cells. European journal of immunology. 2023-09-22. PMID:37736882. |
although antigen stimulation induces release of histamine and serotonin (5-ht) by exocytosis and mast cells express several types of 5-ht receptor, the detailed role of these receptors remains unclear. |
2023-09-22 |
2023-10-07 |
mouse |
| Min-Kyung Joo, Yoon-Jung Shin, Dong-Hyun Ki. Cefaclor causes vagus nerve-mediated depression-like symptoms with gut dysbiosis in mice. Scientific reports. vol 13. issue 1. 2023-09-19. PMID:37726354. |
alterations in central serotonin and 5-ht receptor expression are implicated in the pathogenesis of anxiety and depression, which are highly comorbid with gastrointestinal disorders. |
2023-09-19 |
2023-10-07 |
mouse |
| Min-Kyung Joo, Yoon-Jung Shin, Dong-Hyun Ki. Cefaclor causes vagus nerve-mediated depression-like symptoms with gut dysbiosis in mice. Scientific reports. vol 13. issue 1. 2023-09-19. PMID:37726354. |
cefaclor reduced serotonin levels and fluctuated 5-ht receptor mrna expressions such as htr1a, htr1b, and htr6 in the hippocampus. |
2023-09-19 |
2023-10-07 |
mouse |
| Yu Miyahara, Hideki Funahashi, Ayaka Haruta-Tsukamoto, Yoichiro Kogoh, Anna Kanemaru-Kawazoe, Yoji Hirano, Toshikazu Nishimori, Yasushi Ishid. Differential contribution of 5-HT Biological & pharmaceutical bulletin. 2023-09-18. PMID:37722878. |
differential contribution of 5-ht the involvement of serotonin (5-ht) and/or noradrenaline in acute pruriceptive processing in the central nervous system (cns) has been reported using antidepressants, such as milnacipran, a serotonin and noradrenaline reuptake inhibitor, and mirtazapine, a noradrenergic and specific serotonergic antidepressant; however, the roles of 5-ht receptor family in acute pruriceptive processing have not been fully elucidated in the cns. |
2023-09-18 |
2023-10-07 |
Not clear |
| Doaa Ghorab, Ejlal M Abu-El-Rub, Mohamed Hamdi Gharaibeh, Alaa Yehya, Ramada R Khasawneh, Laila M Matalqah, Ahmed Mohamed Helal. Neurological Effects of Combining Low Toxic Dose of Tramadol and Nicotine: An Animal Model Evidence of Endoplasmic Reticulum Stress. BioMed research international. vol 2023. 2023-08-18. PMID:37593523. |
serotonin receptor blockers such as olanzapine may increase systemic serotonin levels and need further investigation to utterly pinpoint their roles in managing mood disorders. |
2023-08-18 |
2023-09-07 |
rat |
| Juliana Regina Chamlian Zucare Penno, Daniele Pereira Santos-Bezerra, Ana Mercedes Cavaleiro, Ana Maria da Silva Sousa, Tatiana Assunção Zaccara, Rafaela Alkmin da Costa, Rossana Pulcineli Vieira Francisco, Maria Lucia Correa-Giannell. Variant rs17619600 in the gene encoding serotonin receptor 2B (HTR2B) increases the risk of gestational diabetes mellitus: a case-control study. European journal of medical research. vol 28. issue 1. 2023-07-21. PMID:37480094. |
serotonin participates in beta cell adaptation, acting downstream of the prolactin pathway; the blocking of serotonin receptor b (htr2b) signaling in pregnant mice impaired beta cell expansion and caused glucose intolerance. |
2023-07-21 |
2023-08-14 |
mouse |
| Yéssica P López-Echeverri, Kelly J Cardona-Londoño, Jhonny F Garcia-Aguirre, Mary Orrego-Cardoz. Effects of serotonin transporter and receptor polymorphisms on depression. Revista Colombiana de psiquiatria (English ed.). 2023-07-15. PMID:37453823. |
serotonin is highly implicated in the regulation of emotional state and the execution of cognitive tasks, so much so that the serotonin transporter genes (5-htt, slc6a4) and the serotonin receptor genes (htr1a, htr1b, htr2a) have become the perfect candidates when studying the effects that these genes and their polymorphic variations have on depression characteristics. |
2023-07-15 |
2023-08-14 |
Not clear |
| Paria Motahari, Katayoun Katebi, Fatemeh Pournaghi-Azar, Masoumeh Jabbarzade. Association between 5-Hydroxytryptamine Receptor 2A Gene (rs6313 and rs4941573) Polymorphism and Sleep Bruxism: A Meta-analysis. Sleep science (Sao Paulo, Brazil). vol 16. issue 2. 2023-07-10. PMID:37425969. |
even though the association between the, 5-hydroxytryptamine 2a (5-htr2a) serotonin receptor gene polymorphism and sleep bruxism has been investigated, inconsistent findings have been discovered. |
2023-07-10 |
2023-08-14 |
human |
| Zhelun Peng, Qiu Man, Lu Meng, Sheng Wang, Hao Cai, Chuansheng Zhang, Xianyao Li, Heng Wang, Guiyu Zh. A PITX2-HTR1B pathway regulates the asymmetric development of female gonads in chickens. PNAS nexus. vol 2. issue 6. 2023-06-30. PMID:37388922. |
forcibly activating serotonin receptor 5-hydroxytryptamine receptor 1b (htr1b) signaling could induce ovarian gene expression and cell proliferation to partially rescue the degeneration of the right gonad. |
2023-06-30 |
2023-08-14 |
Not clear |
| Qiqi Zhang, Yifang Chang, Changying Zheng, Lijuan Su. Identification and Expression Profiling of the 5-HT Receptor Gene in Insects. vol 14. issue 6. 2023-06-27. PMID:37367324. |
identification and expression profiling of the 5-ht receptor gene in it has been found that 5-hydroxytryptamine (5-ht) modulates the feeding of some insects, and this phenomenon was found in |
2023-06-27 |
2023-08-14 |
Not clear |
| Yuan Pei, Xin Wen, Sheng-Chao Guo, Zhi-Shuai Yang, Ru Zhang, Peng Xiao, Jin-Peng Su. Structural insight into the selective agonist ST1936 binding of serotonin receptor 5-HT6. Biochemical and biophysical research communications. vol 671. 2023-06-16. PMID:37327704. |
the serotonin receptor 5-ht |
2023-06-16 |
2023-08-14 |
Not clear |
| Aida Shahraki, Jana Selent, Peter Kol. On the construction of LIECE models for the serotonin receptor 5-HT[Formula: see text]R. Journal of computer-aided molecular design. 2023-06-13. PMID:37312012. |
on the construction of liece models for the serotonin receptor 5-ht[formula: see text]r. computer-aided approaches to ligand design need to balance accuracy with speed. |
2023-06-13 |
2023-08-14 |
Not clear |
| Pengxin Jiang, Shilin Fang, Nini Huang, Weiqun L. The excitatory effect of 5-HT Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 2023-06-03. PMID:37269940. |
in this study, the effect of 5-ht on the firing activity of dahlgren cells was explored in terms of changes in firing frequency and firing pattern using multicellular recording electrophysiology ex vivo, and the role of several 5-ht receptor subtypes in the regulation was determined. |
2023-06-03 |
2023-08-14 |
Not clear |
| Arushi Chauhan, Jitender Singh, Namrata Sangwan, Radhika Dhawan, Pramod K Avt. An Atomic Level Investigation of Sodium Ions Regulating Agonist and Antagonist Binding in the Active Site of a Novel Target 5HT Cell biochemistry and biophysics. 2023-06-02. PMID:37266904. |
an atomic level investigation of sodium ions regulating agonist and antagonist binding in the active site of a novel target 5ht the study investigates the movement of sodium ions inside the ligand-binding pocket of the class-a gpcr serotonin receptor (5ht |
2023-06-02 |
2023-08-14 |
Not clear |