All Relations between 5-ht receptor and serotonin

Publication Sentence Publish Date Extraction Date Species
Reza Rajabalizadeh, Mahboobeh Ghasemzadeh Rahbardar, Hossein Hosseinzade. Medicinal herbs in treating chemotherapy-induced nausea and vomiting: A review. Phytotherapy research : PTR. 2022-07-16. PMID:35841194. in this manuscript, the antiemetic mechanisms of several herbal medicines and their preparations such as zingiber officinale (5-ht, nk-1 receptor and muscarinic antagonist activity), mentha spicata (5-ht antagonist activity), scutellaria baicalensis (antioxidant activity), persumac (useful in delayed phase through antioxidant, anti-inflammatory, and anti-contractile properties) and rikkunshito (supportive in acute and delayed phase through 5-ht receptor antagonist activity) have been reviewed to show their potential effects on decreasing cinv and attract scientists attention to formulate more herbal medicine to alleviate cinv in cancer patients. 2022-07-16 2023-08-14 Not clear
Keaton A Unroe, Jessica L Maltman, Elizabeth A Shupe, Sarah M Clinto. Disrupted serotonin system development via early life antidepressant exposure impairs maternal care and increases serotonin receptor expression in adult female offspring. Developmental psychobiology. vol 64. issue 6. 2022-06-24. PMID:35748633. these results demonstrate that early alterations to 5-ht signaling through ssri exposure may disrupt nurturing parental behaviors and 5-ht receptor expression in affected female rat offspring. 2022-06-24 2023-08-14 rat
Minhee Kim, Wonil Choi, Jihyeon Yoon, Byung-Kwan Jeong, Suvarna H Pagire, Haushabhau S Pagire, Jungsun Park, Jung Eun Nam, Chang Joo Oh, Jae-Han Jeon, Seong Soon Kim, Byung Hoi Lee, Jin Sook Song, Myung Ae Bae, In-Kyu Lee, Hail Kim, Jin Hee Ah. Synthesis and biological evaluation of tyrosine derivatives as peripheral 5HT European journal of medicinal chemistry. vol 239. 2022-06-22. PMID:35732081. among serotonin receptor subtypes, 5ht 2022-06-22 2023-08-14 Not clear
Amber N Edinoff, Juliana M Fort, Christina Singh, Sarah E Wagner, Jessica R Rodriguez, Catherine A Johnson, Elyse M Cornett, Kevin S Murnane, Adam M Kaye, Alan D Kay. Alternative Options for Complex, Recurrent Pain States Using Cannabinoids, Psilocybin, and Ketamine: A Narrative Review of Clinical Evidence. Neurology international. vol 14. issue 2. 2022-06-01. PMID:35645354. psilocybin, commonly known as "magic mushrooms", works at the serotonin receptor, 5-ht 2022-06-01 2023-08-13 Not clear
Emanuela Dyrmishi, Marco De Pieri, Marco Ferrari, Rafael Traber, Matteo Preve, Luca De Peri, Emilio Boll. Case Report: Long-Acting Oral Cariprazine. Frontiers in psychiatry. vol 13. 2022-05-16. PMID:35573352. cariprazine is a partial agonist at dopamine receptors d2 and d3 and serotonin receptor 5ht1a and an antagonist at serotonin receptors 5ht2b and 5ht2a. 2022-05-16 2023-08-13 Not clear
Nina M Beltran, Jeremiah Ramos, Antonio Landavazo, Bruce Blough, Katherine M Serafin. Eating a High Fat Diet Enhances Sensitivity of Rats to 5-HT FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35555947. to test the hypothesis that eating a high fat diet enhances sensitivity of rats to 5-ht syndrome, male (n=16) and female (n=16) rats eating high fat (60% kcal from fat) or standard (17% kcal from fat) laboratory chow were tested once weekly with cumulative doses of 5-ht receptor agonists, including 8-oh-dpat (0.01-1.0 mg/kg, s.c.), lorcaserin (1.0-32.0 mg/kg, i.p.) 2022-05-13 2023-08-13 rat
Vinay K Sharma, Xuyu Yang, Soo-Kyung Kim, Amirhossain Maafi, Lan Xiao, Aska Inoue, William A Goddard, Y P Lo. 5HTR1E receptor interacts with Neurotrophic factor-α1 and serotonin to activate two distinct signaling pathways. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35557446. we have identified 5-hydroxytryptamine receptor 1e (5htr1e), a gi coupled serotonin receptor, as an extracellular binding partner of nfα1/cpe. 2022-05-13 2023-08-13 Not clear
Elizabeth A Bartlett, Francesca Zanderigo, Denise Shieh, Jeffrey Miller, Patrick Hurley, Harry Rubin-Falcone, Maria A Oquendo, M Elizabeth Sublette, R Todd Ogden, J John Man. Serotonin transporter binding in major depressive disorder: impact of serotonin system anatomy. Molecular psychiatry. 2022-04-29. PMID:35487966. we now investigate 5-htt binding in mdd in two novel ways: (1) use of a 5-htt tract-based analysis examining binding along serotonergic axons; and (2) using the copenhagen university hospital neurobiology research unit (nru) 5-ht atlas, based on brain-wide binding patterns of multiple serotonin receptor types. 2022-04-29 2023-08-13 Not clear
Ann Jane Tierney, Madelyn Haller, Leah Grossman, Hannah Grote, Natalie Marcus-Baue. Serotonergic modulation of appetitive and ingestive behavior in crayfish. Behavioral neuroscience. 2022-03-31. PMID:35357863. we examined the modulation of feeding behavior in crayfish by administering serotonin and two serotonin receptor ligands, mianserin and 5-carboxamidotryptamine. 2022-03-31 2023-08-13 Not clear
Georg A Petroian. Hyperthermia and Serotonin: The Quest for a "Better Cyproheptadine". International journal of molecular sciences. vol 23. issue 6. 2022-03-25. PMID:35328784. based on the theoretical model presented the "ideal" antidote against serotonin syndrome hyperthermia appears to be an antagonist at the 5-ht receptor subtypes 2, 4 and 6 and an agonist at the receptor subtypes 1, 3 and 7. 2022-03-25 2023-08-13 Not clear
Nadeem, Shumaila Usman, Rehan Imad, Uzair Nisar, Irfan Khan, Ghulam Abba. Pre-weaning fluoxetine exposure caused anti-depressant like behavior at adulthood via perturbing tryptophan metabolism in rats. Metabolic brain disease. 2022-03-18. PMID:35303245. additionally, the brain tryptophan, 5-ht (5-hydroxytryptamine) and its metabolite 5-hiaa (5-hydroxyindoleacetic acid) levels were quantified using enzyme linked immunosorbent assay (elisa), while expression of sert (serotonin receptor), 5-ht 2022-03-18 2023-08-13 rat
Nikita Deo, Gregory Redpat. Serotonin Receptor and Transporter Endocytosis Is an Important Factor in the Cellular Basis of Depression and Anxiety. Frontiers in cellular neuroscience. vol 15. 2022-03-14. PMID:35280519. ssris predominantly inhibit sert, preventing serotonin uptake to enhance 5-ht receptor signaling, while hallucinogenic compounds directly activate specific 5-ht receptors, altering their interaction with endocytic adaptor proteins to induce alternate signaling outcomes. 2022-03-14 2023-08-13 Not clear
Robert W Garvey, Enza Lacivita, Mauro Niso, Beata Duszyńska, Paul E Harris, Marcello Leopold. Design, synthesis, and characterization of a novel fluoroprobe for live human islet cell imaging of serotonin 5-HT1A receptor. ChemMedChem. 2022-03-14. PMID:35286016. among the 5-ht receptor subtype found in pancreatic islets, serotonin receptor 1a (5-ht 1a ) demonstrates a unique ability to inhibit beta-cell insulin secretion. 2022-03-14 2023-08-13 human
Xiao Cui Yuan, Yu-Ying Wang, Li-Xia Tian, Xiang-Ji Yan, Yi-Xiao Guo, Yu-Long Zhao, Sani Sa'idu Baba, Hong Jia, Hui-Sheng Wang, Man Li, Fu-Quan Hu. Spinal 5-HT2A Receptor is Involved in Electroacupuncture Inhibition of Chronic Pain. Molecular pain. 2022-03-04. PMID:35240891. however, it is still unclear which among the 5-ht receptor subtype is involved in ea evoked 5-ht mediated inhibition of chronic pain in the dorsal spinal cord. 2022-03-04 2023-08-13 mouse
Avital Fischer, Hedy S Rennert, Gad Renner. Selective serotonin reuptake inhibitors associated with increased mortality risk in breast cancer patients in Northern Israel. International journal of epidemiology. 2022-02-08. PMID:35134960. recent investigation demonstrated serotonin receptor (5-htr2b) expression in the breast and serotonin production as an indicator of poor breast cancer prognosis. 2022-02-08 2023-08-13 Not clear
Lingna Guo, Wenxuan Dai, Zhengrong Xu, Qiaoyi Liang, Eliot T Miller, Shengju Li, Xia Gao, Maude W Baldwin, Renjie Chai, Qian L. Evolution of brain-expressed biogenic amine receptors into olfactory trace amine-associated receptors. Molecular biology and evolution. 2022-01-12. PMID:35021231. we further identify ligands for 61 orphan tarls and taars from sea lamprey, shark, ray-finned fishes, and mammals, as well as novel ligands for two 5-hydroxytryptamine receptor 4 (htr4) orthologs, a serotonin receptor subtype closely related to taars. 2022-01-12 2023-08-13 Not clear
Emma Aaldijk, Yannick Vermeire. The role of serotonin within the microbiota-gut-brain axis in the development of Alzheimer's disease: a narrative review. Ageing research reviews. 2022-01-06. PMID:34990844. of interest, preclinical studies point to serotonergic alterations, either induced via selective serotonin reuptake inhibitors or serotonin receptor (ant)agonists, in mitigating ad brain neuropathology next to its clinical symptoms, the latter being supported by a handful of human intervention trials. 2022-01-06 2023-08-13 mouse
Faranak Vahid-Ansari, Paul R Alber. Rewiring of the Serotonin System in Major Depression. Frontiers in psychiatry. vol 12. 2022-01-03. PMID:34975594. in this review, we survey the possible 5-ht receptor mechanisms that could mediate 5-ht rewiring and assess the evidence that 5-ht-mediated brain rewiring is impacting recovery from mental illness. 2022-01-03 2023-08-13 Not clear
Eline Pottie, Christophe P Stov. In vitro assays for the functional characterization of (psychedelic) substances at the serotonin receptor 5-HT Journal of neurochemistry. 2022-01-03. PMID:34978711. in vitro assays for the functional characterization of (psychedelic) substances at the serotonin receptor 5-ht serotonergic psychedelics are substances that induce alterations in mood, perception and thought, and have the activation of serotonin (5-ht) 2a receptors (5-ht 2022-01-03 2023-08-13 Not clear
Shingo Nakamura, Takahiro Nonaka, Shuji Komatsu, Toshihiko Yamada, Tatsuo Yamamot. Oral acetaminophen-induced spinal 5-hydroxytriyptamine release produces analgesic effects in the rat formalin test. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 146. 2021-12-27. PMID:34959121. in this study, we examined whether acetaminophen and am404 induce spinal 5-ht release and the mechanism through which spinal 5-ht receptor activation exerts analgesic effects in a rat formalin test in an inflammatory pain model. 2021-12-27 2023-08-13 rat