| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Amber N Edinoff, Juliana M Fort, Joshua J Woo, Christopher D Causey, Caroline R Burroughs, Elyse M Cornett, Adam M Kaye, Alan D Kay. Selective Serotonin Reuptake Inhibitors and Clozapine: Clinically Relevant Interactions and Considerations. Neurology international. vol 13. issue 3. 2021-10-02. PMID:34564289. |
the preferential targeting of serotonin receptor (sert) by selective serotonin reuptake inhibitors (ssris) has offered an opportunity to reduce the range of these side effects and improve patient adherence to pharmacotherapy. |
2021-10-02 |
2023-08-13 |
Not clear |
| Chen-Xin Li, Ying Zheng, Hong Zhu, Cheng-Wu Li, Zhang He, Cong Wang, Jian-Hua Ding, Gang Hu, Ming L. β-arrestin 2 is essential for fluoxetine-mediated promotion of hippocampal neurogenesis in a mouse model of depression. Acta pharmacologica Sinica. vol 42. issue 5. 2021-09-27. PMID:33526871. |
emerging evidence suggests that fluoxetine can directly combine with the 5-ht receptor, which is a member of the g protein-coupled receptor (gpcr) family, in addition to suppressing the serotonin transporter. |
2021-09-27 |
2023-08-13 |
mouse |
| Yang Yang, Lijing Zhang, Jiaojiao Yu, Zhaobin Ma, Moxiang Li, Jin Wang, Pengcheng Hu, Jia Zou, Xueying Liu, Ying Liu, Su An, Cheng Xiang, Xiaoxi Guo, Qian Hao, Tian-Rui X. A Novel 5-HT Frontiers in pharmacology. vol 12. 2021-09-25. PMID:34552493. |
a novel 5-ht the serotonin receptor 5-ht |
2021-09-25 |
2023-08-13 |
Not clear |
| April Contreras, Matthew Khumnark, Rochelle M Hines, Dustin J Hine. Behavioral arrest and a characteristic slow waveform are hallmark responses to selective 5-HT Scientific reports. vol 11. issue 1. 2021-09-23. PMID:33479368. |
behavioral arrest and a characteristic slow waveform are hallmark responses to selective 5-ht perception, emotion, and mood are powerfully modulated by serotonin receptor (5-htr) agonists including hallucinogens. |
2021-09-23 |
2023-08-13 |
Not clear |
| Dan Domocos, Tudor Selescu, Laura Cristina Ceafalan, Mirela Iodi Carstens, Earl Carstens, Alexandru Babe. Role of 5-HT1A and 5-HT3 receptors in serotonergic activation of sensory neurons in relation to itch and pain behavior in the rat. Journal of neuroscience research. vol 98. issue 10. 2021-09-17. PMID:32537854. |
using a combination of in vitro (calcium and voltage imaging and patch-clamp) and in vivo behavioral methods, we used both male and female wistar rats to provide evidence for the involvement of two 5-ht receptor subtypes, 5-ht1a and 5-ht3, in mediating the sustained and transient effects, respectively, of 5-ht on rat primary afferent neurons involved in pain and itch processing. |
2021-09-17 |
2023-08-13 |
rat |
| Zahid Parvez Sukhan, Yusin Cho, Md Rajib Sharker, Shaharior Hossen, Sung-Ju Rha, Kang Hee Kh. Effective accumulative temperature affects gonadal maturation by controlling expression of GnRH, GnRH receptor, serotonin receptor and APGWamide gene in Pacific abalone, Haliotis discus hannai during broodstock conditioning in hatcheries. Journal of thermal biology. vol 100. 2021-09-10. PMID:34503784. |
to understand the molecular mechanism underlying the regulation of gonadal maturation and reproduction of haliotis discus hannai exposed to eat and induced spawning period, changes in expression of neuroendocrine genes encoding two gonadotropin releasing hormone (hdh-gnrh, gnrh-like peptide), gnrh receptor (hdhgnrh-r), serotonin receptor (5-ht |
2021-09-10 |
2023-08-13 |
Not clear |
| Caiyun Sun, Yang Qiu, Qin Ren, Xiao Zhang, Baolong Cao, Yi Zou, Juan Li, Jiannan Zhang, Yajun Wan. Molecular Cloning and Functional Characterization of Three 5-HT Receptor Genes ( Genes. vol 12. issue 6. 2021-08-27. PMID:34207786. |
molecular cloning and functional characterization of three 5-ht receptor genes ( the serotonin (5-hydroxytryptamine, 5-ht) signaling system is involved in a variety of physiological functions, including the control of cognition, reward, learning, memory, and vasoconstriction in vertebrates. |
2021-08-27 |
2023-08-13 |
Not clear |
| Marie Hagbom, Arash Hellysaz, Claudia Istrate, Johan Nordgren, Sumit Sharma, Felipe Meira de-Faria, Karl-Eric Magnusson, Lennart Svensso. The 5-HT Journal of virology. vol 95. issue 15. 2021-08-25. PMID:33980599. |
serotonin is released during rotavirus infection, and antagonists to the serotonin receptor subtype 3 (5-ht |
2021-08-25 |
2023-08-13 |
Not clear |
| Cory A Massey, Samantha J Thompson, Ryan W Ostrom, Janice Drabek, Olafur A Sveinsson, Torbjörn Tomson, Elisabeth A Haas, Othon J Mena, Alica M Goldman, Jeffrey L Noebel. X-linked serotonin 2C receptor is associated with a non-canonical pathway for sudden unexpected death in epilepsy. Brain communications. vol 3. issue 3. 2021-08-17. PMID:34396109. |
accordingly, the g protein-coupled, membrane serotonin receptor 5-ht |
2021-08-17 |
2023-08-13 |
mouse |
| Trevor Sharp, Nicholas M Barne. Central 5-HT receptors and their function; present and future. Neuropharmacology. vol 177. 2021-08-12. PMID:32522572. |
since our review of central 5-ht receptors and their function twenty years ago, no new 5-ht receptor has been discovered and there is little evidence that this situation will change in the near future. |
2021-08-12 |
2023-08-13 |
human |
| Trevor Sharp, Nicholas M Barne. Central 5-HT receptors and their function; present and future. Neuropharmacology. vol 177. 2021-08-12. PMID:32522572. |
such highlights include extensive mapping of 5-ht receptors in both animal and human brain, culminating in readily-accessible brain atlases of 5-ht receptor distribution, as well as emerging data on how 5-ht receptors are distributed within complex neural circuits. |
2021-08-12 |
2023-08-13 |
human |
| Trevor Sharp, Nicholas M Barne. Central 5-HT receptors and their function; present and future. Neuropharmacology. vol 177. 2021-08-12. PMID:32522572. |
much more needs to be discovered and understood by 5-ht neuropharmacologists, not least how the diverse signalling effects of so many 5-ht receptor types interact with complex neural circuits to generate neurophysiological changes which ultimately lead to altered cognitions and behaviour. |
2021-08-12 |
2023-08-13 |
human |
| Rose E Presby, Renee A Rotolo, Erin M Hurley, Sarah M Ferrigno, Cayla E Murphy, Haley P McMullen, Pranally A Desai, Emma M Zorda, Felicita B Kuperwasser, Carla Carratala-Ros, Merce Correa, John D Salamon. Sex differences in lever pressing and running wheel tasks of effort-based choice behavior in rats: Suppression of high effort activity by the serotonin transport inhibitor fluoxetine. Pharmacology, biochemistry, and behavior. vol 202. 2021-08-10. PMID:33493546. |
the serotonin receptor mediating the suppressive effects of fluoxetine is uncertain, because serotonin antagonists with different patterns of receptor selectivity failed to reverse the effects of fluoxetine. |
2021-08-10 |
2023-08-13 |
rat |
| Hao Chen, Feng Wang, Xuan Ni, Yi Rigui, Yuxia Bai, Liang Xu, Jingfeng Yang, Xuefu Zhang, Jiang Deng, Jiawei Li, Xiaoyu Yin, Wuliji Ao, Kevin W H Kwok, Wu Don. Aconitine disrupts serotonin neurotransmission via 5-hydroxytryptamine receptor in zebrafish embryo. Journal of applied toxicology : JAT. vol 41. issue 3. 2021-07-12. PMID:33085127. |
experimental results showed that aconitine exposure (1, 10, and 100 μm) increased frequency of coiling behavior in zebrafish embryos in a dose-dependent manner and this effect can be triggered by either exposure to 5-hydroxytryptamine 1a (5-ht1a) receptor agonist (±)-8-hydroxy-2-(dipropylamino)tetralin (8-oh-dpat) or overexpression of serotonin receptor 5-htr1ab. |
2021-07-12 |
2023-08-13 |
zebrafish |
| Simon Bennet Sonnenberg, Jonah Rauer, Christoph Göhr, Nataliya Gorinski, Sophie Kristin Schade, Dalia Abdel Galil, Vladimir Naumenko, André Zeug, Stephan C Bischoff, Evgeni Ponimaskin, Daria Gusev. The 5-HT Journal of cell science. vol 134. issue 4. 2021-07-12. PMID:33536244. |
here, we uncovered a signaling pathway involving the adhesion molecule l1cam (l1) and serotonin receptor 5-ht |
2021-07-12 |
2023-08-13 |
Not clear |
| Jieon Lee, Diana Avramets, Byungsun Jeon, Hyunah Cho. Modulation of Serotonin Receptors in Neurodevelopmental Disorders: Focus on 5-HT7 Receptor. Molecules (Basel, Switzerland). vol 26. issue 11. 2021-07-12. PMID:34199418. |
from this point of view, we noticed the correlation between serotonin receptor subtype 7 (5-ht |
2021-07-12 |
2023-08-13 |
Not clear |
| Johana L Rivera-Fonseca, Nelly González-Rivas, M V Basavanag Unnamatla, Marco A García-Eleno, Horacio Reyes, L Germán López-Valdez, David Corona-Becerril, Erick Cuevas-Yañe. Synthesis and Development of Indole Based 5-HT3 Receptor Antagonists as Anti-Emetic Drugs in Oncology: An Update. Current medicinal chemistry. 2021-07-09. PMID:34238146. |
an important group of anti-emetic drugs used in the treatment of nausea and vomiting after chemotherapy contains an indole moiety in their structures, working as 5-hydroxytryptamine type 3 serotonin receptor antagonist (5-ht3). |
2021-07-09 |
2023-08-13 |
Not clear |
| Kazuhiro Mio, Shoko Fujimura, Masaki Ishihara, Masahiro Kuramochi, Hiroshi Sekiguchi, Tai Kubo, Yuji C Sasak. Living-Cell Diffracted X-ray Tracking Analysis Confirmed Internal Salt Bridge Is Critical for Ligand-Induced Twisting Motion of Serotonin Receptors. International journal of molecular sciences. vol 22. issue 10. 2021-07-02. PMID:34067933. |
the serotonin receptor subtype 2a (5-ht |
2021-07-02 |
2023-08-13 |
Not clear |
| Y V M Lages, A D Rossi, T E Krahe, J Landeira-Fernande. Effect of chronic unpredictable mild stress on the expression profile of serotonin receptors in rats and mice: a meta-analysis. Neuroscience and biobehavioral reviews. vol 124. 2021-06-25. PMID:33524415. |
evidence from animal studies has reported a variety of results regarding the effects of chronic unpredictable mild stress (cums) on serotonin signaling pathways and 5-ht receptor subtypes. |
2021-06-25 |
2023-08-13 |
mouse |
| Elina T L'Estrade, Maria Erlandsson, Fraser G Edgar, Tomas Ohlsson, Gitte M Knudsen, Matthias M Hert. Towards selective CNS PET imaging of the 5-HT Neuropharmacology. vol 172. 2021-06-21. PMID:31669129. |
towards selective cns pet imaging of the 5-ht since its discovery in 1993, the serotonin receptor subtype 7 (5-ht |
2021-06-21 |
2023-08-13 |
Not clear |