| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fernando E Padovan-Neto, Santanna Patterson, Nivea M F Voelkner, Feras Altwal, Joel A Beverley, Anthony R West, Heinz Steine. Selective Regulation of 5-HT1B Serotonin Receptor Expression in the Striatum by Dopamine Depletion and Repeated L-DOPA Treatment: Relationship to L-DOPA-Induced Dyskinesias. Molecular neurobiology. vol 57. issue 2. 2020-11-05. PMID:31468338. |
to further investigate the effects of dopamine and agonists on 5-ht receptors, we assessed the expression of 5-ht1b and other serotonin receptor subtypes in the striatum after unilateral dopamine depletion by 6-ohda and subsequent treatment with l-dopa (5 mg/kg; 4 weeks). |
2020-11-05 |
2023-08-13 |
Not clear |
| He-Fei Li, Jun-Feng Liu, Ke Zhang, Yong Fen. Expression of serotonin receptors in human lower esophageal sphincter. Experimental and therapeutic medicine. vol 9. issue 1. 2020-10-01. PMID:25452775. |
the aim of this study was to explore the expression of multiple types of 5-ht receptor (5-ht |
2020-10-01 |
2023-08-13 |
human |
| Nadine Herr, Christoph Bode, Daniel Duerschmie. The Effects of Serotonin in Immune Cells. Frontiers in cardiovascular medicine. vol 4. 2020-10-01. PMID:28775986. |
the functions of serotonin are mediated by members of the 7 known mammalian serotonin receptor subtype classes (15 known subtypes), the serotonin transporter (sert), and by covalent binding of serotonin to different effector proteins. |
2020-10-01 |
2023-08-13 |
Not clear |
| Dasiel O Borroto-Escuela, Xiang Li, Alexander O Tarakanov, David Savelli, Manuel Narváez, Kirill Shumilov, Yuniesky Andrade-Talavera, Antonio Jimenez-Beristain, Bartosz Pomierny, Zaida Díaz-Cabiale, Riccardo Cuppini, Patrizia Ambrogini, Maria Lindskog, Kjell Fux. Existence of Brain 5-HT1A-5-HT2A Isoreceptor Complexes with Antagonistic Allosteric Receptor-Receptor Interactions Regulating 5-HT1A Receptor Recognition. ACS omega. vol 2. issue 8. 2020-10-01. PMID:28920103. |
studies on serotonin-selective reuptake inhibitors have established that disturbances in the ascending 5-ht neuron systems and their 5-ht receptor subtypes and collateral networks to the forebrain contribute to the etiology of major depression and are targets for treatment. |
2020-10-01 |
2023-08-13 |
Not clear |
| Steffen Vogelgesang, Marcus Niebert, Anne M Bischoff, Swen Hülsmann, Till Manzk. Persistent Expression of Serotonin Receptor 5b Alters Breathing Behavior in Male MeCP2 Knockout Mice. Frontiers in molecular neuroscience. vol 11. 2020-10-01. PMID:29515365. |
mecp2-deficient mice, which recapitulate this breathing phenotype, show a dysregulated, persistent expression of g-protein-coupled serotonin receptor 5-ht |
2020-10-01 |
2023-08-13 |
mouse |
| Wanchao Yin, X Edward Zhou, Dehua Yang, Parker W de Waal, Meitian Wang, Antao Dai, Xiaoqing Cai, Chia-Ying Huang, Ping Liu, Xiaoxi Wang, Yanting Yin, Bo Liu, Yu Zhou, Jiang Wang, Hong Liu, Martin Caffrey, Karsten Melcher, Yechun Xu, Ming-Wei Wang, H Eric Xu, Yi Jian. Crystal structure of the human 5-HT Cell discovery. vol 4. 2020-10-01. PMID:29560272. |
crystal structure of the human 5-ht 5-hydroxytryptamine (5-ht, also known as serotonin) regulates many physiological processes through the 5-ht receptor family. |
2020-10-01 |
2023-08-13 |
human |
| Man Jin, Yali Mo, Kaisheng Ye, Mingxian Chen, Yi Liu, Cao H. Efficacy of serotonin receptor agonists in the treatment of functional dyspepsia: a meta-analysis. Archives of medical science : AMS. vol 15. issue 1. 2020-10-01. PMID:30697251. |
functional dyspepsia (fd) is typically treated with serotonin receptor (5-ht) agonists such as cisapride, mosapride, tegaserod and tandospirone citrate. |
2020-10-01 |
2023-08-13 |
Not clear |
| William J Scotton, Lisa J Hill, Adrian C Williams, Nicholas M Barne. Serotonin Syndrome: Pathophysiology, Clinical Features, Management, and Potential Future Directions. International journal of tryptophan research : IJTR. vol 12. 2020-10-01. PMID:31523132. |
it is characterised by a dose-relevant spectrum of clinical findings related to the level of free serotonin (5-hydroxytryptamine [5-ht]), or 5-ht receptor activation (predominantly the 5-ht |
2020-10-01 |
2023-08-13 |
Not clear |
| Andreas Walther, Christoph Peter, Nevin Yilmaz, Werner Schmidt, Eike Martin, Heinfried Schmid. Influence of serotonin-receptor antagonism on mast cell activation during endotoxemia. Pathophysiology : the official journal of the International Society for Pathophysiology. vol 8. issue 3. 2020-09-30. PMID:12039647. |
conclusions: serotonin receptor antagonism using the 5-ht(1/2/7)-receptor antagonist methysergide or the 5-ht(2a)-receptor antagonist ketanserin reduces endotoxin-induced mast cell activation in-vivo, most probably via the 5-ht(2a)-receptor subtype. |
2020-09-30 |
2023-08-12 |
rat |
| A Ganesh Kumar, K Balamurugan, R Vijaya Raghavan, G Dharani, R Kirubagara. Studies on the antifungal and serotonin receptor agonist activities of the secondary metabolites from piezotolerant deep-sea fungus Mycology. vol 10. issue 2. 2020-09-30. PMID:31069123. |
studies on the antifungal and serotonin receptor agonist activities of the secondary metabolites from piezotolerant deep-sea fungus the potent antifungal agent sesquiterpenes and serotonin 5-ht |
2020-09-30 |
2023-08-13 |
Not clear |
| Md Sharif Shajib, Usha Chauhan, Salman Adeeb, Yeshale Chetty, David Armstrong, Smita L S Halder, John K Marshall, Waliul I Kha. Characterization of Serotonin Signaling Components in Patients with Inflammatory Bowel Disease. Journal of the Canadian Association of Gastroenterology. vol 2. issue 3. 2020-09-30. PMID:31294376. |
secreted 5-ht regulates various gut functions through diverse 5-ht receptor (5-htr) families, and 5-ht transporter (5-htt) sequesters its activity via uptake into surrounding cells. |
2020-09-30 |
2023-08-13 |
Not clear |
| Motohiro Okada, Kouji Fukuyama, Ruri Okubo, Takashi Shiroyama, Yuto Ued. Lurasidone Sub-Chronically Activates Serotonergic Transmission via Desensitization of 5-HT1A and 5-HT7 Receptors in Dorsal Raphe Nucleus. Pharmaceuticals (Basel, Switzerland). vol 12. issue 4. 2020-09-30. PMID:31590422. |
following systemic and local administrations of lurasidone, mk801 and 5-ht receptor modulators, we determined releases of 5-ht in dorsal raphe nucleus (drn), mediodorsal thalamic nucleus (mdtn) and medial prefrontal cortex (mpfc) and γ-aminobutyric acid (gaba) in drn using multiprobe microdialysis with ultra-high-performance liquid chromatography (uhplc). |
2020-09-30 |
2023-08-13 |
Not clear |
| Kei Odai, Tohru Sugimoto, Etsuro It. Biophysics and physicobiology. vol 16. 2020-09-30. PMID:31608202. |
these complicated functions of 5-ht are supported by several 5-ht receptor and 5-ht transporter subtypes. |
2020-09-30 |
2023-08-13 |
Not clear |
| Yessenia Ballou, Alexandria Rivas, Andres Belmont, Luv Patel, Clarissa N Amaya, Shane Lipson, Thuraieh Khayou, Erin B Dickerson, Zeina Nahleh, Brad A Brya. 5-HT serotonin receptors modulate mitogenic signaling and impact tumor cell viability. Molecular and clinical oncology. vol 9. issue 3. 2020-09-29. PMID:30155245. |
previous studies have provided evidence that elevated serotonin (5-ht) and serotonin receptor levels may contribute to oncogenic progression, yet little is known regarding the mechanism by which this occurs. |
2020-09-29 |
2023-08-13 |
Not clear |
| Yessenia Ballou, Alexandria Rivas, Andres Belmont, Luv Patel, Clarissa N Amaya, Shane Lipson, Thuraieh Khayou, Erin B Dickerson, Zeina Nahleh, Brad A Brya. 5-HT serotonin receptors modulate mitogenic signaling and impact tumor cell viability. Molecular and clinical oncology. vol 9. issue 3. 2020-09-29. PMID:30155245. |
the data demonstrated that serotonin receptor mrnas and proteins are expressed across diverse cancer types, and that serotonin stimulation of tumor cells activates oncogenic signaling mediators including components of the akt, creb, gsk3, and mapk pathways. |
2020-09-29 |
2023-08-13 |
Not clear |
| Yann Develle, Hugues Leblon. Biphasic Effect of Buspirone on the H-Reflex in Acute Spinal Decerebrated Mice. Frontiers in cellular neuroscience. vol 13. 2020-09-28. PMID:32009904. |
buspirone, a partial serotonin receptor agonist (5-ht |
2020-09-28 |
2023-08-13 |
mouse |
| Jin-Young Lee, Changwon Yang, Whasun Lim, Gwonhwa Son. Methiothepin Suppresses Human Ovarian Cancer Cell Growth by Repressing Mitochondrion-Mediated Metabolism and Inhibiting Angiogenesis In Vivo. Pharmaceutics. vol 12. issue 7. 2020-09-28. PMID:32698407. |
serotonin has cell growth-promoting functions in a variety of carcinomas, but the effect of serotonin receptor antagonists on ovarian cancer cells is unknown. |
2020-09-28 |
2023-08-13 |
human |
| Jirasuda Nakeim, Napamanee Kornthong, Jirawat Saetan, Supawadee Duangprom, Prasert Sobhon, Prapee Sretarugs. Presence of serotonin and its receptor in the central nervous system and ovary and molecular cloning of the novel crab serotonin receptor of the blue swimming crab, Portunus pelagicus. Acta histochemica. vol 122. issue 1. 2020-09-24. PMID:31708231. |
presence of serotonin and its receptor in the central nervous system and ovary and molecular cloning of the novel crab serotonin receptor of the blue swimming crab, portunus pelagicus. |
2020-09-24 |
2023-08-13 |
Not clear |
| Jirasuda Nakeim, Napamanee Kornthong, Jirawat Saetan, Supawadee Duangprom, Prasert Sobhon, Prapee Sretarugs. Presence of serotonin and its receptor in the central nervous system and ovary and molecular cloning of the novel crab serotonin receptor of the blue swimming crab, Portunus pelagicus. Acta histochemica. vol 122. issue 1. 2020-09-24. PMID:31708231. |
due to the presence of 5-ht receptor we suggest that 5-ht acts primarily at the cns and ovary, thus implicating its role in reproduction especially in the development of oocytes though its exact function in this crab needed to be explored further. |
2020-09-24 |
2023-08-13 |
Not clear |
| Deblina Dey, Vipan K Parihar, Gergely G Szabo, Peter M Klein, Jenny Tran, Jonathan Moayyad, Faizy Ahmed, Quynh-Anh Nguyen, Alexandria Murry, David Merriott, Brandon Nguyen, Jodi Goldman, Maria C Angulo, Daniele Piomelli, Ivan Soltesz, Janet E Baulch, Charles L Limol. Neurological Impairments in Mice Subjected to Irradiation and Chemotherapy. Radiation research. vol 193. issue 5. 2020-09-14. PMID:32134362. |
relevant to the known roles of the serotonin axis in mood disorders, we found that 5ht1a serotonin receptor levels were decreased by ∼50% in the hippocampus at both early and late time points, and a 37% decrease in serotonin levels was observed at 15 weeks postirradiation. |
2020-09-14 |
2023-08-13 |
mouse |