| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Kaur Gill, Y Bansal, R Bhandari, S Kaur, J Kaur, R Singh, A Kuhad, A Kuha. Gepirone hydrochloride: a novel antidepressant with 5-HT1A agonistic properties. Drugs of today (Barcelona, Spain : 1998). vol 55. issue 7. 2019-07-31. PMID:31347611. |
gepirone is a drug of the azapirone group which is a 5-ht1a receptor agonist belonging to the buspirone family. |
2019-07-31 |
2023-08-13 |
Not clear |
| A Kaur Gill, Y Bansal, R Bhandari, S Kaur, J Kaur, R Singh, A Kuhad, A Kuha. Gepirone hydrochloride: a novel antidepressant with 5-HT1A agonistic properties. Drugs of today (Barcelona, Spain : 1998). vol 55. issue 7. 2019-07-31. PMID:31347611. |
clinical studies have shown that gepirone has differential action at pre- and postsynaptic 5-ht1a receptors. |
2019-07-31 |
2023-08-13 |
Not clear |
| Nausheen Alam, Rahila Naja. Buspirone attenuates methylphenidate-induced growth inhibition. Pakistan journal of pharmaceutical sciences. vol 30. issue 2. 2019-07-01. PMID:28649058. |
repeated administration of buspirone attenuates the effectiveness of somatodendritic 5-ht1a receptors. |
2019-07-01 |
2023-08-13 |
Not clear |
| Nausheen Alam, Rahila Naja. Buspirone attenuates methylphenidate-induced growth inhibition. Pakistan journal of pharmaceutical sciences. vol 30. issue 2. 2019-07-01. PMID:28649058. |
it is suggested that buspirone may oppose methylphenidate-induced growth inhibition by decreasing the sensitivity of somatodendritic 5-ht1a receptors. |
2019-07-01 |
2023-08-13 |
Not clear |
| Darakhshan Jabeen Haleem, Shazia Nawaz, Tabinda Salma. Dopamine and serotonin metabolism associated with morphine reward and its inhibition with buspirone: A study in the rat striatum. Pharmacology, biochemistry, and behavior. vol 170. 2019-03-22. PMID:29782941. |
results suggest that 5-ht1a receptor dependent modulation of dopamine neurotransmission in the cn and nac is involved in the modulation of the rewarding effects of morphine in buspirone co-treated animals. |
2019-03-22 |
2023-08-13 |
rat |
| Gregory T Collins, Charles P Franc. Effects of lorcaserin and buspirone, administered alone and as a mixture, on cocaine self-administration in male and female rhesus monkeys. Experimental and clinical psychopharmacology. vol 26. issue 5. 2018-12-11. PMID:29952618. |
two such drugs, lorcaserin (belviq; a drug with serotonin [5-ht]2c receptor agonist properties) and buspirone (buspar; a drug with 5-ht1a receptor partial agonist and dopamine d3/d4 receptor antagonist properties) can produce modest decreases in cocaine self-administration in rhesus monkeys. |
2018-12-11 |
2023-08-13 |
monkey |
| I P Butkevich, V A Mikhailenko, E A Vershinina, M K Astapov. [INVOLVEMENT OF 5-HT1A RECEPTORS IN LONG-TERM INFLUENCE OF INFLAMMATORY PAIN AND STRESS IN EARLY AGE ON REACTIVITY OF NOCICEPTIVE SYSTEM]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 102. issue 8. 2018-10-02. PMID:30193202. |
to study the involvement of 5-ht1a receptors in the long-term impact of neonatal effects on pain sensitivity we used a chronic injection of 5-ht1a receptor agonist buspirone during the prepuberal period of rats which as newborn experienced similar impacts (control, injection of saline). |
2018-10-02 |
2023-08-13 |
rat |
| I P Butkevich, V A Mikhailenko, E A Vershinina, M K Astapov. [INVOLVEMENT OF 5-HT1A RECEPTORS IN LONG-TERM INFLUENCE OF INFLAMMATORY PAIN AND STRESS IN EARLY AGE ON REACTIVITY OF NOCICEPTIVE SYSTEM]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 102. issue 8. 2018-10-02. PMID:30193202. |
thus, effects of buspirone found in this study suggest that 5-ht1a receptors are involved in the long-term influence of the studied adverse neonatal impacts on the reactivity of the nociceptive system. |
2018-10-02 |
2023-08-13 |
rat |
| Manato Kotani, Naoko Urushino, Itaru Natsutani, Yuji Ogi, Kazuhito Iked. Effects of the 5-HT1A receptor agonists buspirone and 8-OH-DPAT on pupil size in common marmosets. Behavioural pharmacology. vol 28. issue 4. 2018-03-06. PMID:27922541. |
effects of the 5-ht1a receptor agonists buspirone and 8-oh-dpat on pupil size in common marmosets. |
2018-03-06 |
2023-08-13 |
Not clear |
| Manato Kotani, Naoko Urushino, Itaru Natsutani, Yuji Ogi, Kazuhito Iked. Effects of the 5-HT1A receptor agonists buspirone and 8-OH-DPAT on pupil size in common marmosets. Behavioural pharmacology. vol 28. issue 4. 2018-03-06. PMID:27922541. |
in this study, we constructed a system for measuring changes in pupil size using an infrared eye-tracking camera and evaluated the effects on pupil size of the 5-ht1a receptor agonists buspirone, 8-oh-dpat and buspirone active metabolite 1-(2-pyrimidinyl) piperazine. |
2018-03-06 |
2023-08-13 |
Not clear |
| Manato Kotani, Naoko Urushino, Itaru Natsutani, Yuji Ogi, Kazuhito Iked. Effects of the 5-HT1A receptor agonists buspirone and 8-OH-DPAT on pupil size in common marmosets. Behavioural pharmacology. vol 28. issue 4. 2018-03-06. PMID:27922541. |
the 5-ht1a receptor antagonist way 100635 completely blocked both buspirone and 8-oh-dpat-induced miosis, whereas 1-(2-pyrimidinyl) piperazine had no effect on pupil size. |
2018-03-06 |
2023-08-13 |
Not clear |
| O A Lyubashina, I I Busygina, S S Panteleev, A D Nozdrache. Antinociceptive effect of the agonist of 5-HT1A receptors buspirone in the model of abdominal pain in dogs. Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections. vol 473. issue 1. 2018-02-23. PMID:28508197. |
antinociceptive effect of the agonist of 5-ht1a receptors buspirone in the model of abdominal pain in dogs. |
2018-02-23 |
2023-08-13 |
Not clear |
| O A Lyubashina, I I Busygina, S S Panteleev, A D Nozdrache. Antinociceptive effect of the agonist of 5-HT1A receptors buspirone in the model of abdominal pain in dogs. Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections. vol 473. issue 1. 2018-02-23. PMID:28508197. |
we have demonstrated that activation of 5-ht1a receptors with buspirone promotes visceral analgesia in awake dogs. |
2018-02-23 |
2023-08-13 |
Not clear |
| Hiroyuki Arakaw. Involvement of serotonin and oxytocin in neural mechanism regulating amicable social signal in male mice: Implication for impaired recognition of amicable cues in BALB/c strain. Behavioral neuroscience. vol 131. issue 2. 2017-11-09. PMID:28301190. |
systemic administration of buspirone (5-ht1a agonist) to stimulus mice also increased approach in b6 recipient mice, whereas a nasal ot antagonist infusion followed by systemic buspirone injection of stimulus mice blocked this buspirone-induced approach in b6 recipient mice. |
2017-11-09 |
2023-08-13 |
mouse |
| George P Karamanolis, Stylianos Panopoulos, Konstantinos Denaxas, Anastasios Karlaftis, Alexandra Zorbala, Dimitrios Kamberoglou, Spiros D Ladas, Petros P Sfikaki. The 5-HT1A receptor agonist buspirone improves esophageal motor function and symptoms in systemic sclerosis: a 4-week, open-label trial. Arthritis research & therapy. vol 18. 2017-11-08. PMID:27586891. |
the 5-ht1a receptor agonist buspirone improves esophageal motor function and symptoms in systemic sclerosis: a 4-week, open-label trial. |
2017-11-08 |
2023-08-13 |
Not clear |
| George P Karamanolis, Stylianos Panopoulos, Konstantinos Denaxas, Anastasios Karlaftis, Alexandra Zorbala, Dimitrios Kamberoglou, Spiros D Ladas, Petros P Sfikaki. The 5-HT1A receptor agonist buspirone improves esophageal motor function and symptoms in systemic sclerosis: a 4-week, open-label trial. Arthritis research & therapy. vol 18. 2017-11-08. PMID:27586891. |
acute administration of the oral 5-ht1a receptor agonist buspirone, which is commonly used as an anxiolytic drug, may improve compromised lower esophageal sphincter function. |
2017-11-08 |
2023-08-13 |
Not clear |
| Jigna Rajesh Kumar, Ramamoorthy Rajkumar, Liying Corinne Lee, Gavin S Daw. Nucleus incertus contributes to an anxiogenic effect of buspirone in rats: Involvement of 5-HT1A receptors. Neuropharmacology. vol 110. issue Pt A. 2017-07-10. PMID:27436722. |
nucleus incertus contributes to an anxiogenic effect of buspirone in rats: involvement of 5-ht1a receptors. |
2017-07-10 |
2023-08-13 |
rat |
| Jigna Rajesh Kumar, Ramamoorthy Rajkumar, Liying Corinne Lee, Gavin S Daw. Nucleus incertus contributes to an anxiogenic effect of buspirone in rats: Involvement of 5-HT1A receptors. Neuropharmacology. vol 110. issue Pt A. 2017-07-10. PMID:27436722. |
we hypothesized that the ni may play a role in the neuropharmacology of buspirone, a clinical anxiolytic which is a 5-ht1a receptor partial agonist and a d2 receptor antagonist. |
2017-07-10 |
2023-08-13 |
rat |
| Jigna Rajesh Kumar, Ramamoorthy Rajkumar, Liying Corinne Lee, Gavin S Daw. Nucleus incertus contributes to an anxiogenic effect of buspirone in rats: Involvement of 5-HT1A receptors. Neuropharmacology. vol 110. issue Pt A. 2017-07-10. PMID:27436722. |
opposing the 5-ht1a agonism but not the d2 antagonism of buspirone in the ni attenuated the anxiogenic effects of systemic buspirone. |
2017-07-10 |
2023-08-13 |
rat |
| Jigna Rajesh Kumar, Ramamoorthy Rajkumar, Liying Corinne Lee, Gavin S Daw. Nucleus incertus contributes to an anxiogenic effect of buspirone in rats: Involvement of 5-HT1A receptors. Neuropharmacology. vol 110. issue Pt A. 2017-07-10. PMID:27436722. |
in conclusion, 5-ht1a receptors in the ni contribute to the anxiogenic effect of an acute high dose of buspirone in rats and may be functionally relevant to physiological anxiety. |
2017-07-10 |
2023-08-13 |
rat |