| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kyoji Okita, Akihiro Shiina, Michiko Nakazato, Masaomi Iy. Tandospirone, a 5-HT1A partial agonist is effective in treating anorexia nervosa: a case series. Annals of general psychiatry. vol 12. issue 1. 2013-03-26. PMID:23497393. |
a 22-year-old female patient with anr and a 23-year-old female patient with anbp were treated successfully with the 5-ht1a partial agonist tandospirone. |
2013-03-26 |
2023-08-12 |
Not clear |
| M Di Stefano, A Papathanasopoulos, K Blondeau, R Vos, V Boecxstaens, R Farré, N Rommel, J Tac. Effect of buspirone, a 5-HT1A receptor agonist, on esophageal motility in healthy volunteers. Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus. vol 25. issue 5. 2012-12-05. PMID:22050410. |
effect of buspirone, a 5-ht1a receptor agonist, on esophageal motility in healthy volunteers. |
2012-12-05 |
2023-08-12 |
human |
| D F Avgustinovich, M K Fomin. [Effects of buspirone on the behavior of female mice in a model of social discomfort]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 98. issue 6. 2012-10-09. PMID:23013007. |
females who had reduced of 5-ht1a receptor sensitivity after 30 day of maintenance in social discomfort conditions also showed a decreased sensitivity on chronic buspirone administration. |
2012-10-09 |
2023-08-12 |
mouse |
| C T Dourish, G A Kennett, G Curzo. The 5-HT1A agonists 8-OH-DPAT, buspirone and ipsapirone attenuate stress-induced anorexia in rats. Journal of psychopharmacology (Oxford, England). vol 1. issue 1. 2012-10-02. PMID:22158750. |
the 5-ht1a agonists 8-oh-dpat, buspirone and ipsapirone attenuate stress-induced anorexia in rats. |
2012-10-02 |
2023-08-12 |
rat |
| K S Panickar, N McNaughto. Dose-response analysis of the effects of buspirone on rearing in rats. Journal of psychopharmacology (Oxford, England). vol 5. issue 1. 2012-10-02. PMID:22282122. |
together with data in the literature, the results suggest that 5-ht1a agonists affect rearing at lower doses than ambulation; that the effects of buspirone in the open field are similar to classical anxiolytics; and that changes in rearing may be more closely related to anxiolytic than muscle relaxant, anti-convulsant and other gaba-mediated effects of the classical anxiolytics. |
2012-10-02 |
2023-08-12 |
rat |
| S Antonato. [The role of serotonergic 2C receptors in neurobiology and treatment of eating disorders]. Psychiatrike = Psychiatriki. vol 18. issue 1. 2012-10-02. PMID:22466431. |
20 groups of male wistar rats, 8 animals each, were intraperitoneal injected 0.05-4.0 mg/kg buspirone (5-ht1a agonist), 1.0 and 3.0 mg/kg mesulergine (5-ht2c antagonist with dopaminergic properties), 5.0 and 10.0 mg/kg m-chlorophenylpiperazine (m-cpp) (5-ht2c/1b agonist) and combinations of mesulergine with buspirone or m-cpp, as well as buspirone with m-cpp at same doses. |
2012-10-02 |
2023-08-12 |
rat |
| S Antonato. [The role of serotonergic 2C receptors in neurobiology and treatment of eating disorders]. Psychiatrike = Psychiatriki. vol 18. issue 1. 2012-10-02. PMID:22466431. |
buspirone due to its action on 5-ht1a autoreceptors seems to affect diet selection indirectly, since its effect on carbohydrate intake is reversed by m-cpp. |
2012-10-02 |
2023-08-12 |
rat |
| Irina P Butkevich, Viktor A Mikhailenko, Elena A Vershinina, Vladimir A Otellin, Anna Maria Alois. Buspirone before prenatal stress protects against adverse effects of stress on emotional and inflammatory pain-related behaviors in infant rats: age and sex differences. Brain research. vol 1419. 2012-08-03. PMID:21937026. |
we recently showed that maternal buspirone, a 5-ht1a receptor agonist, protects against the adverse effects of in utero stress on depression and pain in adult rat offspring. |
2012-08-03 |
2023-08-12 |
rat |
| Irina P Butkevich, Viktor A Mikhailenko, Elena A Vershinina, Vladimir A Otellin, Anna Maria Alois. Buspirone before prenatal stress protects against adverse effects of stress on emotional and inflammatory pain-related behaviors in infant rats: age and sex differences. Brain research. vol 1419. 2012-08-03. PMID:21937026. |
our finding of opposite influences of prenatal stress and buspirone before prenatal stress on formalin-induced pain during the interphase indicates that functional maturity of the descending serotonergic inhibitory system occurs in late infancy males (11-day-olds), and 5-ht1a receptors participate in this process. |
2012-08-03 |
2023-08-12 |
rat |
| Mei Huang, Masakuni Horiguchi, Anna R Felix, Herbert Y Meltze. 5-HT1A and 5-HT7 receptors contribute to lurasidone-induced dopamine efflux. Neuroreport. vol 23. issue 7. 2012-08-02. PMID:22415605. |
further, subeffective doses of the 5-ht1a receptor agonist, tandospirone (0.2 mg/kg), or the 5-ht7 antagonist, sb269970 (0.3 mg/kg), potentiated the ability of a subeffective dose of lurasidone (0.1 mg/kg) to increase da efflux in the prefrontal cortex. |
2012-08-02 |
2023-08-12 |
rat |
| Takashi Uehara, Hiroko Itoh, Tadasu Matsuoka, Dan Rujescu, Just Genius, Tomonori Seo, Tomiki Sumiyosh. Effect of transient blockade of N-methyl-D-aspartate receptors at neonatal stage on stress-induced lactate metabolism in the medial prefrontal cortex of adult rats: role of 5-HT1A receptor agonism. Synapse (New York, N.Y.). vol 66. issue 5. 2012-07-09. PMID:22213269. |
this study was undertaken to determine (1) if transient blockade of n-methyl-d-aspartate receptors during the neonatal stage inhibit energy demands in response to stress, as measured by extracellular lactate concentrations, in the mpfc at the young adult stage, and (2) if tandospirone, a 5-ht1a partial agonist, reverses the effect of the neonatal insult on energy metabolism. |
2012-07-09 |
2023-08-12 |
rat |
| Takashi Uehara, Hiroko Itoh, Tadasu Matsuoka, Dan Rujescu, Just Genius, Tomonori Seo, Tomiki Sumiyosh. Effect of transient blockade of N-methyl-D-aspartate receptors at neonatal stage on stress-induced lactate metabolism in the medial prefrontal cortex of adult rats: role of 5-HT1A receptor agonism. Synapse (New York, N.Y.). vol 66. issue 5. 2012-07-09. PMID:22213269. |
the mk-801-induced suppression of footshock stress-induced lactate production in the mpfc was attenuated by tandospirone at 1.0mg/kg/day, but not 0.1 or 5.0 mg/kg/day, which is an effect antagonized by coadministration of way-100635, a selective 5-ht1a antagonist. |
2012-07-09 |
2023-08-12 |
rat |
| D F Avgustinovich, G B Vishnevetskai. [Effects of chronic buspirone treatment on female mice exposed to the long-lasting psychoemotional influence]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 97. issue 2. 2011-07-19. PMID:21598679. |
the effects of chronic treatment (30 days) with the 5-ht1a receptor partial agonist buspirone (0.05, 1 and 10 mg/kg i.p.) |
2011-07-19 |
2023-08-12 |
mouse |
| Paul R Albert, Brice Le Françoi. Modifying 5-HT1A Receptor Gene Expression as a New Target for Antidepressant Therapy. Frontiers in neuroscience. vol 4. 2011-07-14. PMID:20661455. |
several 5-ht1a receptor agonists (buspirone, flesinoxan, ipsapirone) that preferentially desensitize 5-ht1a autoreceptors have been tested for augmentation of antidepressant drugs with mixed results. |
2011-07-14 |
2023-08-12 |
Not clear |
| Bruno Aouizerate, Dominique Guehl, Emmanuel Cuny, Alain Rougier, Pierre Burbaud, Jean Tignol, Bernard Bioula. Updated overview of the putative role of the serotoninergic system in obsessive-compulsive disorder. Neuropsychiatric disease and treatment. vol 1. issue 3. 2011-05-17. PMID:18568072. |
in contrast, neither mk-212 (6-chloro-2-[1-piperazinyl]-pyrazine), a 5ht1a and 5ht2c receptor agonist, nor ipsapirone or buspirone, which acts as an agonist to 5ht1a receptors, have any effect on oc symptom severity. |
2011-05-17 |
2023-08-12 |
Not clear |
| I Butkevich, V Mikhailenko, E Vershinina, P Semionov, G Makukhina, V Otelli. Maternal buspirone protects against the adverse effects of in utero stress on emotional and pain-related behaviors in offspring. Physiology & behavior. vol 102. issue 2. 2011-04-25. PMID:21056051. |
in the present study we test the hypothesis that injections of buspirone, a 5-ht1a agonist, to rat dams before restraint stress during the last week of pregnancy (between pregnant days 15 and 20) can improve the characteristics of emotional and inflammatory pain-related behaviors in the adult offspring. |
2011-04-25 |
2023-08-12 |
rat |
| Ali Ghaleiha, Ahmad Ali Noorbala, Farhad Farnaghi, Mohammad Hajiazim, Shahin Akhondzade. A double-blind, randomized, and placebo-controlled trial of buspirone added to risperidone in patients with chronic schizophrenia. Journal of clinical psychopharmacology. vol 30. issue 6. 2011-02-22. PMID:21105281. |
the role of partial agonism at 5-ht1a receptors in general and of buspirone in particular remains unclear in the treatment of negative symptoms of schizophrenia. |
2011-02-22 |
2023-08-12 |
Not clear |
| Elsa Maria Valdizán, Elena Castro, Angel Pazo. Agonist-dependent modulation of G-protein coupling and transduction of 5-HT1A receptors in rat dorsal raphe nucleus. The international journal of neuropsychopharmacology. vol 13. issue 7. 2011-01-10. PMID:19895724. |
in order to evaluate the possible existence of agonist-directed trafficking for 5-ht1a autoreceptors in the rat dorsal raphe nucleus, we studied their activation by two agonists with a different profile of efficacy [(+)8-oh-dpat and buspirone], addressing simultaneously the identification of the specific galpha subtypes ([35s]gtpgammas labelling and immunoprecipitation) involved and the subsequent changes in camp formation. |
2011-01-10 |
2023-08-12 |
rat |
| I P Butkevich, V A Mikhaĭlenko, E A Vershinina, P O Semenov, V A Otelli. [Effects of prenatal influences of buspirone and stress on indices of inflammatory pain response and depressive behaviour in adult rats]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 96. issue 4. 2010-07-13. PMID:20564960. |
new data on complex realization of anxiolytic, antidepressive and antinociceptive effects of prenatal injections of a 5-ht1a agonist buspirone were obtained in prenatally stressed adult rats. |
2010-07-13 |
2023-08-12 |
rat |
| b' Esther G\\xc3\\xb3mez-Gil, Ricard Navin\\xc3\\xa9s, M Jes\\xc3\\xbas Mart\\xc3\\xadnez De Osaba, Maribel D\\xc3\\xadaz-Ricart, Gin\\xc3\\xa9s Escolar, Manel Salamero, Roc\\xc3\\xado Mart\\xc3\\xadn-Santos, Ana Gal\\xc3\\xa1n, Crist\\xc3\\xb3bal Gast\\xc3\\xb. Hormonal responses to the 5-HT1A agonist buspirone in remitted endogenous depressive patients after long-term imipramine treatment. Psychoneuroendocrinology. vol 35. issue 4. 2010-06-17. PMID:19762159.' |
hormonal responses to the 5-ht1a agonist buspirone in remitted endogenous depressive patients after long-term imipramine treatment. |
2010-06-17 |
2023-08-12 |
Not clear |