All Relations between 5-ht receptor 1a and dorsal raphe

Publication Sentence Publish Date Extraction Date Species
F Lejeune, M J Milla. Induction of burst firing in ventral tegmental area dopaminergic neurons by activation of serotonin (5-HT)1A receptors: WAY 100,635-reversible actions of the highly selective ligands, flesinoxan and S 15535. Synapse (New York, N.Y.). vol 30. issue 2. 1998-11-16. PMID:9723787. this study examined the influence of the highly selective 5-ht1a receptor ligands, flesinoxan, s 15535, and way 100,635, upon the electrical activity of dopaminergic neurons in the ventral tegmental area (vta), as compared to serotonergic neurons in the dorsal raphe nucleus (drn) of anesthetized rats. 1998-11-16 2023-08-12 rat
R M Sibug, J C Compaan, O C Meijer, J Van der Gugten, B Olivier, E R De Kloe. Flesinoxan treatment reduces 5-HT1A receptor mRNA in the dentate gyrus independently of high plasma corticosterone levels. European journal of pharmacology. vol 353. issue 2-3. 1998-11-13. PMID:9726650. flesinoxan administration resulted in a significant, dose-dependent downregulation of 5-ht1a receptor mrna in the dentate gyrus and dorsal raphe nucleus. 1998-11-13 2023-08-12 rat
H H Hansen, J D Mikkelse. Long-term effects on serotonin transporter mRNA expression of chronic neonatal exposure to a serotonin reuptake inhibitor. European journal of pharmacology. vol 352. issue 2-3. 1998-11-04. PMID:9716368. alterations in the activity of the central 5-ht system are important in understanding the pathophysiology of depression, and therefore, we examined whether this model was associated with changes in the expression of 5-ht1a receptor, 5-ht1b receptor, and 5-ht transporter mrna in the dorsal raphe nucleus and the hippocampus. 1998-11-04 2023-08-12 rat
H H Hansen, J D Mikkelse. Long-term effects on serotonin transporter mRNA expression of chronic neonatal exposure to a serotonin reuptake inhibitor. European journal of pharmacology. vol 352. issue 2-3. 1998-11-04. PMID:9716368. the expression of 5-ht transporter, 5-ht1a receptor, and 5-ht1b receptor mrna was examined in the dorsal raphe nucleus and in the ca1 of the hippocampus by means of quantitative in situ hybridisation histochemistry. 1998-11-04 2023-08-12 rat
J Dong, C de Montigny, P Blie. Full agonistic properties of BAY x 3702 on presynaptic and postsynaptic 5-HT1A receptors electrophysiological studies in the rat hippocampus and dorsal raphe. The Journal of pharmacology and experimental therapeutics. vol 286. issue 3. 1998-10-08. PMID:9732384. full agonistic properties of bay x 3702 on presynaptic and postsynaptic 5-ht1a receptors electrophysiological studies in the rat hippocampus and dorsal raphe. 1998-10-08 2023-08-12 rat
J Dong, C de Montigny, P Blie. Full agonistic properties of BAY x 3702 on presynaptic and postsynaptic 5-HT1A receptors electrophysiological studies in the rat hippocampus and dorsal raphe. The Journal of pharmacology and experimental therapeutics. vol 286. issue 3. 1998-10-08. PMID:9732384. the present studies evaluated the effects of acute and long-term administration of the 5-ht1a agonist bay x 3702 on the responsiveness of dorsal raphe 5-ht neurons and of dorsal hippocampus ca3 pyramidal neurons. 1998-10-08 2023-08-12 rat
M Carli, P Bonalumi, R Samani. Stimulation of 5-HT1A receptors in the dorsal raphe reverses the impairment of spatial learning caused by intrahippocampal scopolamine in rats. The European journal of neuroscience. vol 10. issue 1. 1998-10-08. PMID:9753130. stimulation of 5-ht1a receptors in the dorsal raphe reverses the impairment of spatial learning caused by intrahippocampal scopolamine in rats. 1998-10-08 2023-08-12 rat
M Carli, P Bonalumi, R Samani. Stimulation of 5-HT1A receptors in the dorsal raphe reverses the impairment of spatial learning caused by intrahippocampal scopolamine in rats. The European journal of neuroscience. vol 10. issue 1. 1998-10-08. PMID:9753130. this study investigated the effect of stimulating 5-ht1a receptors in the dorsal raphe on the impairment of learning caused by 4 microg/microl scopolamine injected in the ca1 region of the dorsal hippocampus in rats performing a two-platform spatial discrimination task. 1998-10-08 2023-08-12 rat
M Carli, P Bonalumi, R Samani. Stimulation of 5-HT1A receptors in the dorsal raphe reverses the impairment of spatial learning caused by intrahippocampal scopolamine in rats. The European journal of neuroscience. vol 10. issue 1. 1998-10-08. PMID:9753130. at 1 (but not 0.2) microg/0.5 microl administered in the dorsal raphe on each acquisition training day 5 min before bilateral intrahippocampal injection of 4 microg/microl scopolamine, 8-hydroxy-2-(di-n-propylamino) tetralin (8-oh-dpat), a 5-ht1a receptor agonist, had no effect on choice accuracy and latency or errors of omission but completely antagonized the impairment of choice accuracy by intrahippocampal scopolamine. 1998-10-08 2023-08-12 rat
M Carli, P Bonalumi, R Samani. Stimulation of 5-HT1A receptors in the dorsal raphe reverses the impairment of spatial learning caused by intrahippocampal scopolamine in rats. The European journal of neuroscience. vol 10. issue 1. 1998-10-08. PMID:9753130. administered into the dorsal raphe at 0.2 and 1 microg/0.5 microl, way 100635, a 5-ht1a receptor antagonist, had no effect on rats' performance or on the impairment caused by intrahippocampal scopolamine but dose-dependently antagonized the effect of 1 microg/0.5 microl 8-oh-dpat on the scopolamine-induced deficit. 1998-10-08 2023-08-12 rat
M Carli, P Bonalumi, R Samani. Stimulation of 5-HT1A receptors in the dorsal raphe reverses the impairment of spatial learning caused by intrahippocampal scopolamine in rats. The European journal of neuroscience. vol 10. issue 1. 1998-10-08. PMID:9753130. the results show that stimulation of presynaptic 5-ht1a receptors in the dorsal raphe reverses the deficit caused by intrahippocampal scopolamine, probably by facilitating the transfer of facilitatory information from the entorhinal cortex to the hippocampus. 1998-10-08 2023-08-12 rat
L G Larsson, C Stenfors, S B Ros. Differential regional antagonism of 8-OH-DPAT-induced decrease in serotonin synthesis by two 5-HT1A receptor antagonists. European journal of pharmacology. vol 346. issue 2-3. 1998-09-16. PMID:9652362. since previous studies by others have indicated that the reserve of somatodendritic 5-ht1a receptors is greater in dorsal raphe nucleus innervating frontal cortex and striatum than in median raphe nucleus which mainly innervates hippocampus, the observed different regional potency of the two 5-ht1a receptor antagonists may be explained by this difference in the 5-ht1a receptor reserve. 1998-09-16 2023-08-12 rat
R Corradetti, N Laaris, N Hanoun, A M Laporte, E Le Poul, M Hamon, L Lanfume. Antagonist properties of (-)-pindolol and WAY 100635 at somatodendritic and postsynaptic 5-HT1A receptors in the rat brain. British journal of pharmacology. vol 123. issue 3. 1998-04-13. PMID:9504386. studies were performed on 5-ht1a receptors located on 5-hydroxytryptaminergic neurones in the dorsal raphe nucleus (drn) and on pyramidal cells in the ca1 and ca3 regions of the hippocampus in rat brain slices. 1998-04-13 2023-08-12 rat
J De Vry, R Schohe-Loop, H G Heine, J M Greuel, F Mauler, B Schmidt, H Sommermeyer, T Glase. Characterization of the aminomethylchroman derivative BAY x 3702 as a highly potent 5-hydroxytryptamine1A receptor agonist. The Journal of pharmacology and experimental therapeutics. vol 284. issue 3. 1998-04-09. PMID:9495870. in a rat brain slice preparation containing the dorsal raphe nucleus (drn), a model of somatodendritic 5-ht1a receptor function, bay x 3702 inhibited potently (1 nm) neuronal firing. 1998-04-09 2023-08-12 human
D S Dupuis, C Palmier, F C Colpaert, P J Pauwel. Autoradiography of serotonin 5-HT1A receptor-activated G proteins in guinea pig brain sections by agonist-stimulated [35S]GTPgammaS binding. Journal of neurochemistry. vol 70. issue 3. 1998-03-12. PMID:9489749. [35s]gtpgammas binding was stimulated by the mixed 5-ht1a/5-ht(1b/d) agonist l694247 in brain structures enriched in 5-ht1a binding sites, i.e., hippocampus (+140 +/- 14%), dorsal raphe (+70 +/- 8%), lateral septum (+52 +/- 12%), cingulate (+36 +/- 8%), and entorhinal cortex (+34 +/- 5%). 1998-03-12 2023-08-12 Not clear
H Razani, P B Hedlund, A C Hansson, K Fuxe, S O Ogre. 5-HT1A receptor activation: short-term effects on the mRNA expression of the 5-HT1A receptor and galanin in the raphe nuclei. Neuroreport. vol 8. issue 16. 1998-02-26. PMID:9427327. 8-oh-dpat increased the hybridization signal of the 5-ht1a receptor by 105% in the dorsal raphe nucleus (b7) 30 min after the injection. 1998-02-26 2023-08-12 Not clear
H Razani, P B Hedlund, A C Hansson, K Fuxe, S O Ogre. 5-HT1A receptor activation: short-term effects on the mRNA expression of the 5-HT1A receptor and galanin in the raphe nuclei. Neuroreport. vol 8. issue 16. 1998-02-26. PMID:9427327. the results also indicate a dissociation between the effects mediated by 5-ht1a receptor functions and those regulating the coexisting peptide galanin in the dorsal raphe. 1998-02-26 2023-08-12 Not clear
R Corradetti, A M Pugliese, E Le Poul, N Laaris, M Hamon, L Lanfume. Electrophysiological effects of WAY 100635, a new 5-HT1A receptor antagonist, on dorsal raphe nucleus serotoninergic neurones and CA1 pyramidal cells in vitro. Acta physiologica Hungarica. vol 84. issue 4. 1998-02-02. PMID:9328615. electrophysiological effects of way 100635, a new 5-ht1a receptor antagonist, on dorsal raphe nucleus serotoninergic neurones and ca1 pyramidal cells in vitro. 1998-02-02 2023-08-12 Not clear
R Corradetti, A M Pugliese, E Le Poul, N Laaris, M Hamon, L Lanfume. Electrophysiological effects of WAY 100635, a new 5-HT1A receptor antagonist, on dorsal raphe nucleus serotoninergic neurones and CA1 pyramidal cells in vitro. Acta physiologica Hungarica. vol 84. issue 4. 1998-02-02. PMID:9328615. the novel 5-ht1a receptor antagonist way 100635 [(n-(2-(-4(2-metoxyphenyl)-1-piperazinyl)ethyl)-n-(2-pyridinyl)cyc lohexane carboxamide)] has been tested on 5-ht1a receptor-mediated inhibition of firing and intracellularly recorded hyperpolarisation of serotoninergic cells of the dorsal raphe nucleus (drn) and on hyperpolarisation of hippocampal ca1 pyramidal cells. 1998-02-02 2023-08-12 Not clear
R Ciccocioppo, I Panocka, C Polidori, C T Dourish, M Mass. Blockade of pre- and post-synaptic 5-HT1A receptors does not modify the effect of fluoxetine or 5-hydroxytryptophan on ethanol and food intake in rats. Psychopharmacology. vol 134. issue 1. 1998-01-27. PMID:9399367. blockade of presynaptic 5-ht1a receptors after injection of (+)way100135, 0.1 or 1 microgram/rat, into the dorsal raphe did not significantly modify ethanol, food or total fluid intake. 1998-01-27 2023-08-12 rat