All Relations between 5-ht receptor 1a and dorsal raphe

Publication Sentence Publish Date Extraction Date Species
B Bjorvatn, S Fagerland, T Eid, R Ursi. Sleep/waking effects of a selective 5-HT1A receptor agonist given systemically as well as perfused in the dorsal raphe nucleus in rats. Brain research. vol 770. issue 1-2. 1998-01-21. PMID:9372206. sleep/waking effects of a selective 5-ht1a receptor agonist given systemically as well as perfused in the dorsal raphe nucleus in rats. 1998-01-21 2023-08-12 rat
B Bjorvatn, S Fagerland, T Eid, R Ursi. Sleep/waking effects of a selective 5-HT1A receptor agonist given systemically as well as perfused in the dorsal raphe nucleus in rats. Brain research. vol 770. issue 1-2. 1998-01-21. PMID:9372206. sleep/waking stages and behavior were studied following the selective 5-ht1a agonist 8-oh-dpat given subcutaneously (s.c.) (0.010-0.375 mg/kg) as well as perfused continuously (10 microm) for 6 h into the dorsal raphe nucleus (drn) using microdialysis. 1998-01-21 2023-08-12 rat
E Le Poul, N Laaris, M Hamon, L Lanfume. Fluoxetine-induced desensitization of somatodendritic 5-HT1A autoreceptors is independent of glucocorticoid(s). Synapse (New York, N.Y.). vol 27. issue 4. 1998-01-14. PMID:9372553. previous in vitro studies showed that glucocorticoid receptor activation (notably by corticosterone) could induce a functional desensitization of somatodendritic 5-ht1a autoreceptors in the dorsal raphe nucleus [laaris et al. 1998-01-14 2023-08-12 rat
L J Sim, R Xiao, S R Childer. In vitro autoradiographic localization of 5-HT1A receptor-activated G-proteins in the rat brain. Brain research bulletin. vol 44. issue 1. 1998-01-09. PMID:9288830. [35s]gtpgammas autoradiography, performed in brain sections with the 5-ht1a agonist 8-oh-dpat, revealed high levels of 5-ht1a-stimulated [35s]gtpgammas binding in the hippocampus, lateral septum, prelimbic cortex, entorhinal cortex, and dorsal raphe nucleus. 1998-01-09 2023-08-12 rat
J M Casanovas, M Lésourd, F Artiga. The effect of the selective 5-HT1A agonists alnespirone (S-20499) and 8-OH-DPAT on extracellular 5-hydroxytryptamine in different regions of rat brain. British journal of pharmacology. vol 122. issue 4. 1998-01-02. PMID:9375971. we have examined the effects of the systemic administration of the selective 5-ht1a agonist alnespirone (s-20499) on in vivo 5-hydroxytryptamine (5-ht) release in the dorsal raphe nucleus, the median raphe nucleus and four forebrain areas innervated differentially by both (dorsal striatum, frontal cortex, ventral hippocampus and dorsal hippocampus). 1998-01-02 2023-08-12 rat
J Dong, C de Montigny, P Blie. Effect of acute and repeated versus sustained administration of the 5-HT1A receptor agonist ipsapirone: electrophysiological studies in the rat hippocampus and dorsal raphe. Naunyn-Schmiedeberg's archives of pharmacology. vol 356. issue 3. 1997-10-27. PMID:9303566. effect of acute and repeated versus sustained administration of the 5-ht1a receptor agonist ipsapirone: electrophysiological studies in the rat hippocampus and dorsal raphe. 1997-10-27 2023-08-12 rat
J Dong, C de Montigny, P Blie. Effect of acute and repeated versus sustained administration of the 5-HT1A receptor agonist ipsapirone: electrophysiological studies in the rat hippocampus and dorsal raphe. Naunyn-Schmiedeberg's archives of pharmacology. vol 356. issue 3. 1997-10-27. PMID:9303566. the present study was aimed at examining the adaptation of presynaptic 5-ht1a autoreceptors in the dorsal raphe and of postsynaptic 5-ht1a receptors in the dorsal hippocampus during long-term administration of the 5-ht1a receptor agonist ipsapirone given either repeatedly or in a sustained fashion. 1997-10-27 2023-08-12 rat
M B Viana, F G Graeff, P A Löschman. Kainate microinjection into the dorsal raphe nucleus induces 5-HT release in the amygdala and periaqueductal gray. Pharmacology, biochemistry, and behavior. vol 58. issue 1. 1997-09-30. PMID:9264086. earlier results obtained in one of our laboratories showed that microinjection into the dorsal raphe nucleus (drn) of the excitatory amino acid kainic acid, the benzodiazepine (bzd) inverse agonist fg 7142, and the 5-ht1a receptor agonist 8-ohdpat changed the behavior of rats in the elevated t-maze, an animal model of anxiety. 1997-09-30 2023-08-12 rat
N Laaris, E Le Poul, M Hamon, L Lanfume. Stress-induced alterations of somatodendritic 5-HT1A autoreceptor sensitivity in the rat dorsal raphe nucleus--in vitro electrophysiological evidence. Fundamental & clinical pharmacology. vol 11. issue 3. 1997-09-04. PMID:9243251. stress-induced alterations of somatodendritic 5-ht1a autoreceptor sensitivity in the rat dorsal raphe nucleus--in vitro electrophysiological evidence. 1997-09-04 2023-08-12 rat
N Laaris, E Le Poul, M Hamon, L Lanfume. Stress-induced alterations of somatodendritic 5-HT1A autoreceptor sensitivity in the rat dorsal raphe nucleus--in vitro electrophysiological evidence. Fundamental & clinical pharmacology. vol 11. issue 3. 1997-09-04. PMID:9243251. somatodendritic 5-ht1a autoreceptors play a key role in the control of the electrical and metabolic activity of serotoninergic neurons in the dorsal raphe nucleus. 1997-09-04 2023-08-12 rat
N Laaris, E Le Poul, M Hamon, L Lanfume. Stress-induced alterations of somatodendritic 5-HT1A autoreceptor sensitivity in the rat dorsal raphe nucleus--in vitro electrophysiological evidence. Fundamental & clinical pharmacology. vol 11. issue 3. 1997-09-04. PMID:9243251. these data show that some forms of stress can reduce the 5-ht1a autoreceptor-dependent inhibitory control of the electrophysiological activity of serotoninergic neurons in the dorsal raphe nucleus. 1997-09-04 2023-08-12 rat
R G Johnson, D Fiorella, J C Winter, R A Rabi. [3H]8-OH-DPAT labels a 5-HT site coupled to inhibition of phosphoinositide hydrolysis in the dorsal raphe. European journal of pharmacology. vol 329. issue 1. 1997-08-22. PMID:9218690. the present study was undertaken to compare the properties of the [3h]8-oh-dpat (8-hydroxy-2-(di-n-propylamino)tetralin) binding site in the dorsal raphe nucleus with the hippocampal 5-ht1a receptor. 1997-08-22 2023-08-12 Not clear
R G Johnson, D Fiorella, J C Winter, R A Rabi. [3H]8-OH-DPAT labels a 5-HT site coupled to inhibition of phosphoinositide hydrolysis in the dorsal raphe. European journal of pharmacology. vol 329. issue 1. 1997-08-22. PMID:9218690. [3h]8-oh-dpat appears to bind to a single population of binding sites in both the hippocampus and the dorsal raphe nucleus, although the k(d) for the radioligand at the dorsal raphe site was five times that observed at the hippocampal 5-ht1a receptor. 1997-08-22 2023-08-12 Not clear
R G Johnson, D Fiorella, J C Winter, R A Rabi. [3H]8-OH-DPAT labels a 5-HT site coupled to inhibition of phosphoinositide hydrolysis in the dorsal raphe. European journal of pharmacology. vol 329. issue 1. 1997-08-22. PMID:9218690. similarly, although 5-ht and selective 5-ht1a receptor ligands displayed high affinity for the [3h]8-oh-dpat binding site in the dorsal raphe nucleus, the affinity at the dorsal raphe site was less than that observed at the hippocampal 5-ht1a receptor. 1997-08-22 2023-08-12 Not clear
R G Johnson, D Fiorella, J C Winter, R A Rabi. [3H]8-OH-DPAT labels a 5-HT site coupled to inhibition of phosphoinositide hydrolysis in the dorsal raphe. European journal of pharmacology. vol 329. issue 1. 1997-08-22. PMID:9218690. an inhibition of phosphoinositide hydrolysis in the dorsal raphe nucleus also was found with the putative 5-ht1a receptor selective ligands, flesinoxan and gepirone. 1997-08-22 2023-08-12 Not clear
R G Johnson, D Fiorella, J C Winter, R A Rabi. [3H]8-OH-DPAT labels a 5-HT site coupled to inhibition of phosphoinositide hydrolysis in the dorsal raphe. European journal of pharmacology. vol 329. issue 1. 1997-08-22. PMID:9218690. these studies demonstrate that the 8-oh-dpat binding site in the dorsal raphe nucleus displays a binding profile which is similar to the hippocampal 5-ht1a receptor, but unlike this 5-ht1a receptor the binding site in the dorsal raphe nucleus is negatively coupled to phosphoinositide turnover. 1997-08-22 2023-08-12 Not clear
A R Allen, A Singh, Z P Zhuang, M P Kung, H F Kung, I Luck. The 5-HT1A receptor antagonist p-MPPI blocks responses mediated by postsynaptic and presynaptic 5-HT1A receptors. Pharmacology, biochemistry, and behavior. vol 57. issue 1-2. 1997-07-30. PMID:9164586. pretreatment with p-mppi also blocked the ability of 8-oh-dpat to reduce extracellular 5-ht in the striatum, a response mediated by presynaptic 5-ht1a receptors in the dorsal raphe nucleus, but did not alter striatal 5-ht when administered alone. 1997-07-30 2023-08-12 Not clear
R K Raghupathi, P McGonigl. Differential effects of three acute stressors on the serotonin 5-HT1A receptor system in rat brain. Neuroendocrinology. vol 65. issue 4. 1997-07-18. PMID:9142996. analysis of presynaptic 5-ht1a receptors in the raphe nuclei revealed an increase in antagonist binding in the dorsal raphe following long swim stress. 1997-07-18 2023-08-12 rat
L Romero, F Artiga. Preferential potentiation of the effects of serotonin uptake inhibitors by 5-HT1A receptor antagonists in the dorsal raphe pathway: role of somatodendritic autoreceptors. Journal of neurochemistry. vol 68. issue 6. 1997-06-17. PMID:9166757. preferential potentiation of the effects of serotonin uptake inhibitors by 5-ht1a receptor antagonists in the dorsal raphe pathway: role of somatodendritic autoreceptors. 1997-06-17 2023-08-12 Not clear
L Romero, F Artiga. Preferential potentiation of the effects of serotonin uptake inhibitors by 5-HT1A receptor antagonists in the dorsal raphe pathway: role of somatodendritic autoreceptors. Journal of neurochemistry. vol 68. issue 6. 1997-06-17. PMID:9166757. together, these data suggest that dorsal raphe neurons projecting to striatum and frontal cortex are more sensitive to self-inhibition mediated by 5-ht1a autoreceptors than median raphe neurons projecting to the hippocampus. 1997-06-17 2023-08-12 Not clear