| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N Haddjeri, G Lucas, P Blie. Role of cholinergic and GABAergic systems in the feedback inhibition of dorsal raphe 5-HT neurons. Neuroreport. vol 11. issue 15. 2001-02-08. PMID:11059909. |
in the present study, the muscarinic (m) receptor antagonists atropine and scopolamine as well as the m2 receptor antagonist af-dx 116, but not the preferential m1 receptor antagonist pirenzepine, reduced the suppressant effect of the 5-ht1a receptor agonist 8-oh-dpat on the spontaneous firing activity of rat dorsal raphe 5-ht neurons. |
2001-02-08 |
2023-08-12 |
rat |
| E G Meloni, M Davi. Synergistic enhancement of the acoustic startle reflex by dopamine D1 and 5-HT1A agonists and corresponding changes in c-Fos expression in the dorsal raphe of rats. Psychopharmacology. vol 151. issue 4. 2001-01-18. PMID:11026743. |
synergistic enhancement of the acoustic startle reflex by dopamine d1 and 5-ht1a agonists and corresponding changes in c-fos expression in the dorsal raphe of rats. |
2001-01-18 |
2023-08-12 |
rat |
| J M Casanovas, O Berton, P Celada, F Artiga. In vivo actions of the selective 5-HT1A receptor agonist BAY x 3702 on serotonergic cell firing and release. Naunyn-Schmiedeberg's archives of pharmacology. vol 362. issue 3. 2001-01-05. PMID:10997727. |
we investigated the effects of the novel 5-ht1a receptor agonist bay x 3702 on the serotonergic function in rat brain using single unit recordings in the dorsal raphe nucleus (dr) of anesthetized rats and in vivo microdialysis in freely moving rats. |
2001-01-05 |
2023-08-12 |
rat |
| J F Czachura, K Rasmusse. Effects of acute and chronic administration of fluoxetine on the activity of serotonergic neurons in the dorsal raphe nucleus of the rat. Naunyn-Schmiedeberg's archives of pharmacology. vol 362. issue 3. 2001-01-05. PMID:10997729. |
these results support the hypothesis that desensitization of the 5-ht1a receptor and consequent recovery of firing of 5-ht cells in the dorsal raphe nucleus plays a role in the delayed therapeutic onset of fluoxetine. |
2001-01-05 |
2023-08-12 |
rat |
| L Arborelius, L Linnér, C Wallsten, S Ahlenius, T H Svensso. Partial 5-HT1A receptor agonist properties of (-)pindolol in combination with citalopram on serotonergic dorsal raphe cell firing in vivo. Psychopharmacology. vol 151. issue 1. 2000-12-28. PMID:10958120. |
partial 5-ht1a receptor agonist properties of (-)pindolol in combination with citalopram on serotonergic dorsal raphe cell firing in vivo. |
2000-12-28 |
2023-08-12 |
Not clear |
| V Fabre, C Beaufour, A Evrard, A Rioux, N Hanoun, K P Lesch, D L Murphy, L Lanfumey, M Hamon, M P Martre. Altered expression and functions of serotonin 5-HT1A and 5-HT1B receptors in knock-out mice lacking the 5-HT transporter. The European journal of neuroscience. vol 12. issue 7. 2000-09-19. PMID:10947809. |
specific labelling with radioligands and antibodies, and competitive rt-pcr, showed that 5-ht1a receptor protein and mrna levels were significantly decreased in the dorsal raphe nucleus (drn), increased in the hippocampus and unchanged in other forebrain areas of 5-htt-/- vs. 5-htt+/+ mice. |
2000-09-19 |
2023-08-12 |
mouse |
| J M Monti, D Mont. Role of dorsal raphe nucleus serotonin 5-HT1A receptor in the regulation of REM sleep. Life sciences. vol 66. issue 21. 2000-06-23. PMID:10823340. |
role of dorsal raphe nucleus serotonin 5-ht1a receptor in the regulation of rem sleep. |
2000-06-23 |
2023-08-12 |
Not clear |
| L Lanfumey, M C Pardon, N Laaris, C Joubert, N Hanoun, M Hamon, C Cohen-Salmo. 5-HT1A autoreceptor desensitization by chronic ultramild stress in mice. Neuroreport. vol 10. issue 16. 2000-02-28. PMID:10599847. |
this treatment produced a significant decrease in the potency of the 5-ht1a agonist ipsapirone to inhibit the electrical activity of serotoninergic neurons in the dorsal raphe nucleus, without modifying 5-ht1a receptor binding in various brain areas. |
2000-02-28 |
2023-08-12 |
mouse |
| C Davidson, J A Stamfor. Effect of chronic paroxetine treatment on 5-HT1B and 5-HT1D autoreceptors in rat dorsal raphe nucleus. Neurochemistry international. vol 36. issue 2. 2000-02-25. PMID:10676872. |
these data suggest that chronic paroxetine treatment may desensitise 5-ht1b autoreceptors in the dorsal raphe nucleus but that this effect is unmasked only when the dominant 5-ht1a autoreceptor control is antagonised. |
2000-02-25 |
2023-08-12 |
rat |
| E Le Poul, C Boni, N Hanoun, A M Laporte, N Laaris, J Chauveau, M Hamon, L Lanfume. Differential adaptation of brain 5-HT1A and 5-HT1B receptors and 5-HT transporter in rats treated chronically with fluoxetine. Neuropharmacology. vol 39. issue 1. 2000-02-18. PMID:10665824. |
electrophysiological recordings in brain slices showed that chronic fluoxetine treatment reduced the potency of the 5-ht1a agonist 8-hydroxy-2-(di-n-propylamino)tetralin to inhibit neuronal activity in the dorsal raphe nucleus, but did not affect 5-ht1a-evoked responses of ca1 pyramidal cells in the hippocampus. |
2000-02-18 |
2023-08-12 |
rat |
| G Juckel, U Hegerl, M Molnár, V Csépe, G Karmo. Auditory evoked potentials reflect serotonergic neuronal activity--a study in behaving cats administered drugs acting on 5-HT1A autoreceptors in the dorsal raphe nucleus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 21. issue 6. 2000-01-28. PMID:10633476. |
auditory evoked potentials reflect serotonergic neuronal activity--a study in behaving cats administered drugs acting on 5-ht1a autoreceptors in the dorsal raphe nucleus. |
2000-01-28 |
2023-08-12 |
Not clear |
| G Juckel, U Hegerl, M Molnár, V Csépe, G Karmo. Auditory evoked potentials reflect serotonergic neuronal activity--a study in behaving cats administered drugs acting on 5-HT1A autoreceptors in the dorsal raphe nucleus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 21. issue 6. 2000-01-28. PMID:10633476. |
the present study examines the effects of microinjection of a 5-ht1a agonist (8-oh-dpat) and a 5-ht1a antagonist (spiperone) into the dorsal raphe nucleus (drn) on aep recorded epidurally from the primary and secondary auditory cortex in behaving cats. |
2000-01-28 |
2023-08-12 |
Not clear |
| M Carli, C Balducci, M J Millan, P Bonalumi, R Samani. S 15535, a benzodioxopiperazine acting as presynaptic agonist and postsynaptic 5-HT1A receptor antagonist, prevents the impairment of spatial learning caused by intrahippocampal scopolamine. British journal of pharmacology. vol 128. issue 6. 2000-01-24. PMID:10578133. |
4 way 100635, a 5-ht1a receptor antagonist, injected into the dorsal raphe at 1.0 microg 0.5 microl-1 5 min before scopolamine, had no effect on choice accuracy and latency or errors of omission and did not modify the effect of scopolamine but completely antagonized the effect of s 15535 (1.0 mg kg-1) on scopolamine-induced impairment of choice accuracy. |
2000-01-24 |
2023-08-12 |
Not clear |
| M Carli, C Balducci, M J Millan, P Bonalumi, R Samani. S 15535, a benzodioxopiperazine acting as presynaptic agonist and postsynaptic 5-HT1A receptor antagonist, prevents the impairment of spatial learning caused by intrahippocampal scopolamine. British journal of pharmacology. vol 128. issue 6. 2000-01-24. PMID:10578133. |
5 the results confirm a previous report (carli et al., 1998) that stimulation of presynaptic 5-ht1a receptors in the dorsal raphe counteracts the deficit caused by intrahippocampal scopolamine, probably by facilitating the transfer of facilitatory information from the entorhinal cortex to the hippocampus. |
2000-01-24 |
2023-08-12 |
Not clear |
| A Evrard, A M Laporte, M Chastanet, R Hen, M Hamon, J Adrie. 5-HT1A and 5-HT1B receptors control the firing of serotoninergic neurons in the dorsal raphe nucleus of the mouse: studies in 5-HT1B knock-out mice. The European journal of neuroscience. vol 11. issue 11. 1999-12-28. PMID:10583471. |
5-ht1a and 5-ht1b receptors control the firing of serotoninergic neurons in the dorsal raphe nucleus of the mouse: studies in 5-ht1b knock-out mice. |
1999-12-28 |
2023-08-12 |
mouse |
| A Evrard, A M Laporte, M Chastanet, R Hen, M Hamon, J Adrie. 5-HT1A and 5-HT1B receptors control the firing of serotoninergic neurons in the dorsal raphe nucleus of the mouse: studies in 5-HT1B knock-out mice. The European journal of neuroscience. vol 11. issue 11. 1999-12-28. PMID:10583471. |
altogether, these data indicate that in the mouse, the firing of 5-ht neurons in the dorsal raphe nucleus is under both an inhibitory control through 5-ht1a receptors and an excitatory influence through 5-ht1b receptors. |
1999-12-28 |
2023-08-12 |
mouse |
| J S Sprouse, L S Reynolds, J P Braselton, H Rollema, S H Zor. Comparison of the novel antipsychotic ziprasidone with clozapine and olanzapine: inhibition of dorsal raphe cell firing and the role of 5-HT1A receptor activation. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 21. issue 5. 1999-11-15. PMID:10516958. |
comparison of the novel antipsychotic ziprasidone with clozapine and olanzapine: inhibition of dorsal raphe cell firing and the role of 5-ht1a receptor activation. |
1999-11-15 |
2023-08-12 |
rat |
| J S Sprouse, L S Reynolds, J P Braselton, H Rollema, S H Zor. Comparison of the novel antipsychotic ziprasidone with clozapine and olanzapine: inhibition of dorsal raphe cell firing and the role of 5-HT1A receptor activation. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 21. issue 5. 1999-11-15. PMID:10516958. |
the goal of the present study was to examine the 5-ht1a properties of ziprasidone in vivo using as a marker of central 5-ht1a activity the inhibition of firing of serotonin-containing neurons in the dorsal raphe nucleus. |
1999-11-15 |
2023-08-12 |
rat |
| S Herges, D A Taylo. Modulation of cocaine-induced locomotor activity, rears and head bobs by application of WAY100635 into the dorsal and median raphe nuclei of the rat. Naunyn-Schmiedeberg's archives of pharmacology. vol 360. issue 2. 1999-11-08. PMID:10494881. |
it may be suggested from these results that stimulation of somatodendritic 5-ht1a autoreceptors located in the dorsal raphe nucleus mediates an inhibitory effect on cocaine-induced locomotor activity and head bobs, whereas somatodendritic 5-ht1a autoreceptors in the median raphe nucleus are not involved in the inhibitory role of 5-ht on the stimulant effect of cocaine on locomotor activity and head bobs. |
1999-11-08 |
2023-08-12 |
rat |
| C Roberts, D F Boyd, D N Middlemiss, C Routledg. Enhancement of 5-HT1B and 5-HT1D receptor antagonist effects on extracellular 5-HT levels in the guinea-pig brain following concurrent 5-HT1A or 5-HT re-uptake site blockade. Neuropharmacology. vol 38. issue 9. 1999-10-25. PMID:10471095. |
the aim of the study was to further investigate the autoreceptor roles of the 5-ht1a, 5-ht1b and 5-ht1d receptors in the median vs dorsal raphe nuclei. |
1999-10-25 |
2023-08-12 |
Not clear |