| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Adam Wojtas, Agnieszka Bysiek, Agnieszka Wawrzczak-Bargiela, Marzena Maćkowiak, Krystyna Gołembiowsk. Limbic System Response to Psilocybin and Ketamine Administration in Rats: A Neurochemical and Behavioral Study. International journal of molecular sciences. vol 25. issue 1. 2024-01-11. PMID:38203271. |
the changes in d2, 5-ht1a and 5-ht2a receptor density in the nucleus accumbens and hippocampus were observed as a long-lasting effect. |
2024-01-11 |
2024-01-13 |
rat |
| Noelia Cantero-García, Antonio Flores-Burgess, Juan Pedro Pineda-Gómez, Laura Orio, Antonia Serrano, Zaida Díaz-Cabiale, Carmelo Milló. Galanin N-terminal fragment (1-15) reduces alcohol seeking and alcohol relapse in rats: Involvement of mesocorticolimbic system. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 153. 2022-09-09. PMID:36076594. |
notably, the mechanism of gal(1-15)-mediated actions involved changes in c-fos, dopamine receptors and 5ht1a expression in the ventral tegmental area, accumbens nucleus and prefrontal cortex. |
2022-09-09 |
2023-08-14 |
rat |
| Darakhshan Jabeen Haleem, Tabinda Salman, Shazia Nawaz, Huma Ikra. Co-treatment with low doses of buspirone prevents rewarding effects of methylphenidate and upregulates expression of 5-HT1A receptor mRNA in the nucleus accumbens. Behavioural brain research. vol 418. 2021-12-11. PMID:34752844. |
animals treated with mpd exhibit a downregulation of 5-ht1a receptor mrna in the nucleus accumbens which is also prevented in rats co-treated with 0.1 and 0.3 mg/kg but not 1.0 and 2.0 mg/kg buspirone. |
2021-12-11 |
2023-08-13 |
rat |
| Darakhshan Jabeen Haleem, Tabinda Salman, Shazia Nawaz, Huma Ikra. Co-treatment with low doses of buspirone prevents rewarding effects of methylphenidate and upregulates expression of 5-HT1A receptor mRNA in the nucleus accumbens. Behavioural brain research. vol 418. 2021-12-11. PMID:34752844. |
co-treatment with low doses of buspirone prevents rewarding effects of methylphenidate and upregulates expression of 5-ht1a receptor mrna in the nucleus accumbens. |
2021-12-11 |
2023-08-13 |
rat |
| Darakhshan Jabeen Haleem, Tabinda Salman, Shazia Nawaz, Huma Ikra. Co-treatment with low doses of buspirone prevents rewarding effects of methylphenidate and upregulates expression of 5-HT1A receptor mRNA in the nucleus accumbens. Behavioural brain research. vol 418. 2021-12-11. PMID:34752844. |
administration of buspirone in these doses is not rewarding in cpp test and upregulates 5-ht1a receptor mrna in the nucleus accumbens. |
2021-12-11 |
2023-08-13 |
rat |
| Kara A Clissold, Eugene Choi, Wayne E Prat. Serotonin 1A, 1B, and 7 receptors of the rat medial nucleus accumbens differentially regulate feeding, water intake, and locomotor activity. Pharmacology, biochemistry, and behavior. vol 112. 2014-07-16. PMID:24125784. |
food-deprived rats were given 2-h access to rat chow after stimulation of nucleus accumbens 5-ht1a, 5-ht1b, or 5-ht7 receptors, or blockade of the 5-ht1a or 5-ht1b receptors. |
2014-07-16 |
2023-08-12 |
rat |
| Mei Huang, John J Panos, Sunoh Kwon, Yoshihiro Oyamada, Lakshmi Rajagopal, Herbert Y Meltze. Comparative effect of lurasidone and blonanserin on cortical glutamate, dopamine, and acetylcholine efflux: role of relative serotonin (5-HT)2A and DA D2 antagonism and 5-HT1A partial agonism. Journal of neurochemistry. vol 128. issue 6. 2014-05-14. PMID:24164459. |
using microdialysis and ultra performance liquid chromatography-mass spectrometry/mass spectrometry, we compared the abilities of the typical apd, haloperidol, three aapds, blonanserin, lurasidone, and olanzapine, and a selective 5-ht1a partial agonist, tandospirone, and all, except haloperidol, were found to ameliorate the cognitive deficits produced by the n-methyl-d-aspartate antagonist, phencyclidine, altering the efflux of neurotransmitters and metabolites in the rat cortex and nucleus accumbens. |
2014-05-14 |
2023-08-12 |
rat |
| Man Li, Xiaofang Xue, Shuang Shao, Feng Shao, Weiwen Wan. Cognitive, emotional and neurochemical effects of repeated maternal separation in adolescent rats. Brain research. vol 1518. 2014-01-07. PMID:23623774. |
previous studies have reported that ms affected prepulse inhibition (ppi), anxiety-related behaviors, dopaminergic and serotonergic activity in adult rats, and in the present study, we investigated the effects of repeated (4h/day) maternal separation during postnatal days 1-21 on ppi and anxiety-related behaviors in an elevated plus maze, as well as dopamine d2 receptor (drd2) and 5-ht1a receptor expression in the medial prefrontal cortex (mpfc), nucleus accumbens (nac) and hippocampus in adolescent rats. |
2014-01-07 |
2023-08-12 |
rat |
| Katerina Zavitsanou, Victoria S Dalton, Adam K Walker, Cynthia S Weickert, Luba Sominsky, Deborah M Hodgso. Neonatal lipopolysaccharide treatment has long-term effects on monoaminergic and cannabinoid receptors in the rat. Synapse (New York, N.Y.). vol 67. issue 6. 2013-10-29. PMID:23389966. |
neonatal lps treatment caused a significant increase in dopamine d2 in the nucleus accumbens and olfactory tubercle, a decrease in 5ht1a receptor binding in the hippocampus ca1 and ventromedial hypothalamus. |
2013-10-29 |
2023-08-12 |
rat |
| Christine M Andrews, Hank F Kung, Irwin Luck. The 5-HT1A receptor modulates the effects of cocaine on extracellular serotonin and dopamine levels in the nucleus accumbens. European journal of pharmacology. vol 508. issue 1-3. 2005-07-14. PMID:15680262. |
taken together, these findings suggest that the 5-ht1a autoreceptor acts to modulate the effects of cocaine on both 5-ht and dopamine levels in the nucleus accumbens. |
2005-07-14 |
2023-08-12 |
Not clear |
| Christine M Andrews, Hank F Kung, Irwin Luck. The 5-HT1A receptor modulates the effects of cocaine on extracellular serotonin and dopamine levels in the nucleus accumbens. European journal of pharmacology. vol 508. issue 1-3. 2005-07-14. PMID:15680262. |
the 5-ht1a receptor modulates the effects of cocaine on extracellular serotonin and dopamine levels in the nucleus accumbens. |
2005-07-14 |
2023-08-12 |
Not clear |
| C P Müller, H Thönnessen, G Jocham, M Barros, C Tomaz, R J Carey, J P Husto. Cocaine-induced 'active immobility' and its modulation by the serotonin1A receptor. Behavioural pharmacology. vol 15. issue 7. 2005-02-17. PMID:15472570. |
two experiments with local activation of postsynaptic 5-ht1a receptors revealed that both nucleus accumbens and hippocampal 5-ht1a-receptor populations are involved in the expression of cocaine-induced ai. |
2005-02-17 |
2023-08-12 |
Not clear |
| I Nagaoka, M Sasa, S Yamawak. 5-HT1A receptor-mediated inhibition of nucleus accumbens neurons activated by stimulation of parafascicular nucleus of thalamus. Psychopharmacology. vol 135. issue 3. 1998-04-23. PMID:9498725. |
electrophysiological studies using chloral hydrate-anesthetized rats were performed to elucidate the role of serotonin1a (5-ht1a) receptors in the regulation of neuronal activity of nucleus accumbens (acc) neurons receiving input from the parafascicular nucleus of the thalamus (pf). |
1998-04-23 |
2023-08-12 |
rat |
| I Nagaoka, M Sasa, S Yamawak. 5-HT1A receptor-mediated inhibition of nucleus accumbens neurons activated by stimulation of parafascicular nucleus of thalamus. Psychopharmacology. vol 135. issue 3. 1998-04-23. PMID:9498725. |
5-ht1a receptor-mediated inhibition of nucleus accumbens neurons activated by stimulation of parafascicular nucleus of thalamus. |
1998-04-23 |
2023-08-12 |
rat |
| A Plaznik, R Stefański, M Jessa, M Nazar, A Bidzińsk. Central serotonergic system and mechanism of anxiolytic action. Acta physiologica Hungarica. vol 84. issue 4. 1998-02-02. PMID:9328628. |
the results clearly indicate that the hippocampus, rather than nucleus accumbens is involved in mediating anxiolytic-like effects of the 5-ht1a receptor agonists. |
1998-02-02 |
2023-08-12 |
Not clear |
| T Obradovic, K M Imel, S R Whit. Methylenedioxymethamphetamine-induced inhibition of neuronal firing in the nucleus accumbens is mediated by both serotonin and dopamine. Neuroscience. vol 74. issue 2. 1997-01-06. PMID:8865198. |
serotonin and serotonin agonists with relative selectivity for the receptor subtypes 5-ht1a, 5-ht1b, 5-ht2a/2c and 5-ht3 all significantly (p < 0.01) inhibited glutamate-evoked firing of cells in the nucleus accumbens compared to the effects of an acidic saline control solution (30-60 na, 60 s ejection currents for all). |
1997-01-06 |
2023-08-12 |
Not clear |
| G G Nomikos, L Arborelius, B B Höök, U Hacksell, T H Svensso. The 5-HT1A receptor antagonist (S)-UH-301 decreases dopamine release in the rat nucleus accumbens and striatum. Journal of neural transmission (Vienna, Austria : 1996). vol 103. issue 5. 1996-12-10. PMID:8811500. |
in this study we employed in vivo microdialysis to examine the effects of the selective 5-ht1a receptor antagonist (s)-5-fluoro-8-hydroxy-2-(dipropylamino)tetralin [(s)-uh-301] on extracellular concentrations of dopamine (da) and its metabolites dihydroxyphenylacetic acid (dopac) and homovanillic acid (hva) in the nucleus accumbens (nac) and dorsal striatum of awake freely moving rats. |
1996-12-10 |
2023-08-12 |
rat |
| G G Nomikos, L Arborelius, B B Höök, U Hacksell, T H Svensso. The 5-HT1A receptor antagonist (S)-UH-301 decreases dopamine release in the rat nucleus accumbens and striatum. Journal of neural transmission (Vienna, Austria : 1996). vol 103. issue 5. 1996-12-10. PMID:8811500. |
the 5-ht1a receptor antagonist (s)-uh-301 decreases dopamine release in the rat nucleus accumbens and striatum. |
1996-12-10 |
2023-08-12 |
rat |
| J Ichikawa, T Kuroki, M T Kitchen, H Y Meltze. R(+)-8-OH-DPAT, a 5-HT1A receptor agonist, inhibits amphetamine-induced dopamine release in rat striatum and nucleus accumbens. European journal of pharmacology. vol 287. issue 2. 1996-10-24. PMID:8749033. |
r(+)-8-oh-dpat, a 5-ht1a receptor agonist, inhibits amphetamine-induced dopamine release in rat striatum and nucleus accumbens. |
1996-10-24 |
2023-08-12 |
rat |
| A Płaźnik, W Kostowski, R Stefańsk. Limbic mechanisms of anxiolytics acting on 5-HT receptors. Polish journal of pharmacology. vol 46. issue 5. 1995-04-24. PMID:7894537. |
the role of brain serotonergic system innervating hippocampus and nucleus accumbens in the anxiolytic-like action of the 5-ht1a receptor agonists and 5-ht3 receptor antagonists, is discussed. |
1995-04-24 |
2023-08-12 |
Not clear |